Page last updated: 2024-10-24

verapamil and Left Ventricular Outflow Obstruction

verapamil has been researched along with Left Ventricular Outflow Obstruction in 12 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"The pericardial effusion was interpreted as part of a postcardiotomy syndrome."1.30[Transitory left ventricular outflow tract obstruction after mitral valve reconstruction]. ( Hauber, J; Rein, JG; Sigel, H, 1999)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (75.00)18.2507
2000's1 (8.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sorajja, P1
Ommen, SR1
Nishimura, RA1
Cotrim, CA1
Adame, PR1
Pereira, HH1
Maron, BJ2
McKenna, WJ2
Danielson, GK1
Kappenberger, LJ1
Kuhn, HJ1
Seidman, CE2
Shah, PM1
Spencer, WH1
Spirito, P2
Ten Cate, FJ1
Wigle, ED1
Tamborini, G1
Pepi, M1
Susini, G1
Salvi, L1
Fiorentini, C1
Tendera, M2
Schneeweiss, A1
Bartoszewski, A1
Polonski, L2
Wodniecki, J2
Salamon, A1
Sherrid, MV1
Gunsburg, DZ1
Pearle, G1
Hauber, J1
Rein, JG1
Sigel, H1
Fananapazir, L1
Cannon, RO1
Tripodi, D1
Panza, JA1
Wheeldon, NM1
Pringle, TH1
Lipworth, BJ1
Kardaszewicz, P1
Gerstenblith, G1
Schulman, SP1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy[NCT04133532]Phase 422 participants (Actual)Interventional2020-03-05Completed
Correlation Between Myocardial Deformation and Coronary Artery Morphology in Patients With Hypertrophic Cardiomyopathy and Analysis of Genetic Factors:A Prospective, Single-center, Case-control Study[NCT04830787]302 participants (Actual)Observational2017-12-01Completed
Obstructive Hypertrophic Cardiomyopathy (HCM) in Children: Natural History and Results of Dual Chamber (DDD) Pacemaker Therapy[NCT00001396]Phase 1100 participants Interventional1993-10-06Completed
Long-Term Results of DDD Pacing in Obstructive Hypertrophic Cardiomyopathy[NCT00001530]120 participants Observational1996-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for verapamil and Left Ventricular Outflow Obstruction

ArticleYear
American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European S
    Journal of the American College of Cardiology, 2003, Nov-05, Volume: 42, Issue:9

    Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Pacing, Artificial;

2003
American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European S
    Journal of the American College of Cardiology, 2003, Nov-05, Volume: 42, Issue:9

    Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Pacing, Artificial;

2003
American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European S
    Journal of the American College of Cardiology, 2003, Nov-05, Volume: 42, Issue:9

    Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Pacing, Artificial;

2003
American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European S
    Journal of the American College of Cardiology, 2003, Nov-05, Volume: 42, Issue:9

    Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Pacing, Artificial;

2003
The management of hypertrophic cardiomyopathy.
    The New England journal of medicine, 1997, Mar-13, Volume: 336, Issue:11

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Cardiac Pacing, Artificial; Cardiomyopathy, Hypert

1997

Trials

1 trial available for verapamil and Left Ventricular Outflow Obstruction

ArticleYear
Influence of left ventricular mass regression on cardiac function in hypertensive elderly individuals.
    European journal of clinical pharmacology, 1990, Volume: 39 Suppl 1

    Topics: Aged; Atenolol; Cardiomegaly; Double-Blind Method; Humans; Hypertension; Middle Aged; Physical Exert

1990

Other Studies

9 other studies available for verapamil and Left Ventricular Outflow Obstruction

ArticleYear
Symptomatic obstructive hypertrophic cardiomyopathy.
    Circulation. Cardiovascular interventions, 2013, Oct-01, Volume: 6, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Cardiomyopathy, Hypertrophic; Diagnosis, Differential; Disease-Fr

2013
Exercise echocardiography in hypertrophic cardiomyopathy-upright evaluation needed.
    The American journal of cardiology, 2011, Apr-01, Volume: 107, Issue:7

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Drug Therapy, C

2011
Reversal of cardiogenic shock and severe mitral regurgitation through verapamil in hypertensive hypertrophic cardiomyopathy.
    Chest, 1993, Volume: 104, Issue:1

    Topics: Aged; Aortic Aneurysm, Abdominal; Aortic Rupture; Cardiomyopathy, Hypertrophic; Humans; Hypertension

1993
The acute response of left ventricular filling dynamics to intravenous verapamil predicts the changes in exercise tolerance after oral verapamil therapy in patients with hypertrophic cardiomyopathy.
    European heart journal, 1993, Volume: 14, Issue:3

    Topics: Administration, Oral; Adult; Aged; Cardiomyopathy, Hypertrophic; Diastole; Exercise Tolerance; Femal

1993
Mid-systolic drop in left ventricular ejection velocity in obstructive hypertrophic cardiomyopathy--the lobster claw abnormality.
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 1997, Volume: 10, Issue:7

    Topics: Acceleration; Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Blood Flow Velocity; Calciu

1997
[Transitory left ventricular outflow tract obstruction after mitral valve reconstruction].
    Deutsche medizinische Wochenschrift (1946), 1999, Sep-24, Volume: 124, Issue:38

    Topics: Adrenergic beta-Antagonists; Adult; Echocardiography; Follow-Up Studies; Heart Valve Prosthesis Impl

1999
Impact of dual-chamber permanent pacing in patients with obstructive hypertrophic cardiomyopathy with symptoms refractory to verapamil and beta-adrenergic blocker therapy.
    Circulation, 1992, Volume: 85, Issue:6

    Topics: Adrenergic beta-Antagonists; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Hy

1992
Impact of dual-chamber permanent pacing in patients with obstructive hypertrophic cardiomyopathy with symptoms refractory to verapamil and beta-adrenergic blocker therapy.
    Circulation, 1992, Volume: 85, Issue:6

    Topics: Adrenergic beta-Antagonists; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Hy

1992
Impact of dual-chamber permanent pacing in patients with obstructive hypertrophic cardiomyopathy with symptoms refractory to verapamil and beta-adrenergic blocker therapy.
    Circulation, 1992, Volume: 85, Issue:6

    Topics: Adrenergic beta-Antagonists; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Hy

1992
Impact of dual-chamber permanent pacing in patients with obstructive hypertrophic cardiomyopathy with symptoms refractory to verapamil and beta-adrenergic blocker therapy.
    Circulation, 1992, Volume: 85, Issue:6

    Topics: Adrenergic beta-Antagonists; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Hy

1992
Obstructive left ventricular hypertrophy. Reversibility of outflow tract obstruction by drug therapy.
    The Quarterly journal of medicine, 1992, Volume: 84, Issue:304

    Topics: Aged; Aged, 80 and over; Atenolol; Echocardiography, Doppler; Female; Humans; Hypertrophy, Left Vent

1992
Evolution of the electrocardiographic changes in patients with hypertrophic cardiomyopathy.
    Clinical cardiology, 1991, Volume: 14, Issue:11

    Topics: Adolescent; Adult; Age Factors; Cardiomyopathy, Hypertrophic; Causality; Child; Echocardiography; El

1991