verapamil has been researched along with Iron Overload in 8 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Liver fibrosis is the principal cause of morbidity and mortality in patients with iron overload." | 1.43 | Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis. ( Chang, Y; Chu, L; Chu, X; Gao, Y; Guo, H; Liu, Z; Wang, N; Zhang, J; Zhang, X; Zhang, Y; Zhao, X, 2016) |
| "Verapamil treatment reduced both cardiac (P < 0." | 1.37 | Interdependence of cardiac iron and calcium in a murine model of iron overload. ( Brewer, C; Otto-Duessel, M; Wood, JC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 1 |
| Lin, X | 1 |
| Pornprasert, S | 1 |
| Lü, X | 1 |
| Ran, B | 1 |
| Lin, Y | 1 |
| Shan, HL | 1 |
| Wang, Y | 1 |
| Wu, JW | 1 |
| Hang, PZ | 1 |
| Li, X | 1 |
| Sun, LH | 1 |
| Qi, JC | 1 |
| Mao, YY | 1 |
| Sun, ZD | 1 |
| Du, ZM | 1 |
| Zhang, Y | 4 |
| Wang, H | 1 |
| Cui, L | 1 |
| Liu, Y | 1 |
| Chu, X | 2 |
| Liu, Z | 2 |
| Zhang, J | 2 |
| Chu, L | 2 |
| Zhao, X | 1 |
| Chang, Y | 1 |
| Zhang, X | 1 |
| Guo, H | 1 |
| Wang, N | 1 |
| Gao, Y | 1 |
| Sugishita, K | 1 |
| Asakawa, M | 1 |
| Usui, S | 1 |
| Takahashi, T | 1 |
| Otto-Duessel, M | 1 |
| Brewer, C | 1 |
| Wood, JC | 1 |
| Kumfu, S | 1 |
| Chattipakorn, S | 1 |
| Fucharoen, S | 1 |
| Chattipakorn, N | 1 |
| Oudit, GY | 1 |
| Sun, H | 1 |
| Trivieri, MG | 1 |
| Koch, SE | 1 |
| Dawood, F | 1 |
| Ackerley, C | 1 |
| Yazdanpanah, M | 1 |
| Wilson, GJ | 1 |
| Schwartz, A | 1 |
| Liu, PP | 1 |
| Backx, PH | 1 |
8 other studies available for verapamil and Iron Overload
| Article | Year |
|---|---|
L-type calcium channel blockers decrease the iron overload-mediated oxidative stress in renal epithelial cells by reducing iron accumulation.
Topics: Apoptosis; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cation Transport Proteins; E | 2020 |
Verapamil reverses cardiac iron overload in streptozocin-induced diabetic rats.
Topics: Animals; Anti-Arrhythmia Agents; Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus, Experim | 2013 |
Continuing treatment with Salvia miltiorrhiza injection attenuates myocardial fibrosis in chronic iron-overloaded mice.
Topics: Animals; Collagen Type I; Collagen Type III; Deferoxamine; Drugs, Chinese Herbal; Endomyocardial Fib | 2015 |
Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis.
Topics: Animals; Apoptosis; Calcium Channel Blockers; Cell Line; Collagen; Deferoxamine; Diltiazem; Hepatic | 2016 |
A case of iron overload cardiomyopathy: beneficial effects of iron chelating agent and calcium channel blocker on left ventricular dysfunction.
Topics: Aged, 80 and over; Calcium Channel Blockers; Cardiomyopathies; Deferoxamine; Ferritins; Humans; Iron | 2009 |
Interdependence of cardiac iron and calcium in a murine model of iron overload.
Topics: Animals; Calcitriol; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, | 2011 |
Ferric iron uptake into cardiomyocytes of β-thalassemic mice is not through calcium channels.
Topics: Animals; Azoles; beta-Thalassemia; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-T | 2013 |
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy.
Topics: Amlodipine; Animals; Biological Transport; Calcium Channel Blockers; Calcium Channels; Cardiomyopath | 2003 |