verapamil has been researched along with Intraocular Pressure in 18 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the influence of the calcium channel blocker verapamil on the development of glaucoma in the adrenalin-induced experimental model of glaucoma." | 7.72 | The influence of the calcium channel blocker verapamil on experimental glaucoma. ( Kashintseva, LT; Kopp, OP; Krizhanovsky, GN; Lipovetskaya, EM; Mikheytseva, IN, 2004) |
| "A novel technique is described in which the effect of the beta-adrenoceptor antagonists timolol and carteolol, and the vasodilators sodium nitroprusside (SNP) and verapamil on intraocular pressure (IOP) and the distribution of ocular flow in the bovine arterially perfused eye is investigated using radiolabelled microspheres." | 7.69 | Drug effects on intraocular pressure and vascular flow in the bovine perfused eye using radiolabelled microspheres. ( Carr, RD; Humphries, RG; Millar, JC; Wilson, WS, 1995) |
| " When applied topically, verapamil and nifedipine effectively lower intraocular pressure." | 7.69 | A complex interaction between topical verapamil and timolol on intraocular pressure in conscious rabbits. ( Garrido, M; Martínez de Ibarreta, MJ; Melena, J; Santafé, J; Segarra, J, 1996) |
| "We investigated the effect of the calcium channel blocker verapamil on intraocular pressure in human volunteers." | 7.67 | Sustained reduction of intraocular pressure in humans with the calcium channel blocker verapamil. ( Abelson, MB; Gilbert, CM; Smith, LM, 1988) |
| " The time-course of the ocular effects of topical verapamil and nifedipine as well as the dose-response relationship, were studied in conscious, normotensive rabbits." | 5.29 | The topical application of verapamil and nifedipine lowers intraocular pressure in conscious rabbits. ( Garrido, M; Martínez de Ibarreta, MJ; Santafé, J; Segarra, J, 1993) |
| "As glaucoma is one of the most significant causes of blindness, and administration of calcium channel blockers is effective in reducing intraocular pressure (IOP) in rabbits and patients with normotensive glaucoma, we administered topical verapamil 0." | 5.14 | Comparative study of topical application of timolol and verapamil in patients with glaucoma within 6 months. ( Boloorian, AA; Kianoush, S; Shayegan, MR, 2009) |
| "There were no significant differences in preoperative mean intraocular pressure, mean number of medications, and glaucoma severity between the verapamil and placebo groups." | 5.09 | Topical verapamil in glaucoma filtration surgery. ( Hughes, BA; Juzych, MS; Kardasis, CT; Keole, NS; Kim, C; Shin, DH, 2001) |
| "To investigate the effect of topical administration of the calcium channel blocker verapamil on intraocular pressure and retrobulbar hemodynamics." | 5.08 | Color Doppler ultrasound analysis of ocular circulation after topical calcium channel blocker. ( Feke, GT; Grosskreutz, CL; Hart, LJ; Netland, PA, 1995) |
| "Our purpose was to investigate the effects of the calcium channel blocker verapamil on intraocular pressure and blood circulation in the human optic nerve head." | 5.08 | Optic nerve head circulation after topical calcium channel blocker. ( Feke, GT; Fujio, N; Goger, DG; Konno, S; Netland, PA, 1996) |
| "25% verapamil on episcleral venous pressure (EVP) and intraocular pressure (IOP)." | 5.08 | Topical verapamil and episcleral venous pressure. ( Abreu, MM; Kim, YY; Netland, PA; Shin, DH, 1998) |
| "To study the influence of the calcium channel blocker verapamil on the development of glaucoma in the adrenalin-induced experimental model of glaucoma." | 3.72 | The influence of the calcium channel blocker verapamil on experimental glaucoma. ( Kashintseva, LT; Kopp, OP; Krizhanovsky, GN; Lipovetskaya, EM; Mikheytseva, IN, 2004) |
| "A novel technique is described in which the effect of the beta-adrenoceptor antagonists timolol and carteolol, and the vasodilators sodium nitroprusside (SNP) and verapamil on intraocular pressure (IOP) and the distribution of ocular flow in the bovine arterially perfused eye is investigated using radiolabelled microspheres." | 3.69 | Drug effects on intraocular pressure and vascular flow in the bovine perfused eye using radiolabelled microspheres. ( Carr, RD; Humphries, RG; Millar, JC; Wilson, WS, 1995) |
| "Verapamil, a calcium channel antagonist, causes a reduction of intraocular pressure in humans." | 3.69 | Verapamil increases outflow facility in the human eye. ( Erickson, KA; Netland, PA; Schroeder, A, 1995) |
| "Topical administration of three different calcium channel blockers (verapamil hydrochloride, diltiazem hydrochloride, or nifedipine) increased intraocular pressure transiently in rabbits." | 3.67 | Elevation of intraocular pressure by calcium channel blockers. ( Beatty, JF; Becker, B; Krupin, T; Nichols, PF, 1984) |
| "We investigated the effect of the calcium channel blocker verapamil on intraocular pressure in human volunteers." | 3.67 | Sustained reduction of intraocular pressure in humans with the calcium channel blocker verapamil. ( Abelson, MB; Gilbert, CM; Smith, LM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 12 (66.67) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shayegan, MR | 1 |
| Boloorian, AA | 1 |
| Kianoush, S | 1 |
| Mikheytseva, IN | 1 |
| Kashintseva, LT | 1 |
| Krizhanovsky, GN | 1 |
| Kopp, OP | 1 |
| Lipovetskaya, EM | 1 |
| Beatty, JF | 1 |
| Krupin, T | 1 |
| Nichols, PF | 1 |
| Becker, B | 1 |
| Netland, PA | 5 |
| Grosskreutz, CL | 1 |
| Feke, GT | 2 |
| Hart, LJ | 1 |
| Kaji, Y | 1 |
| Hiraki, S | 1 |
| Hirata, H | 1 |
| Ettl, A | 1 |
| Daxer, A | 1 |
| Hofmann, U | 1 |
| Segarra, J | 3 |
| Santafé, J | 3 |
| Garrido, M | 2 |
| Martínez de Ibarreta, MJ | 2 |
| Chaturvedi, N | 1 |
| Dreyer, EB | 1 |
| Millar, JC | 1 |
| Wilson, WS | 1 |
| Carr, RD | 1 |
| Humphries, RG | 1 |
| Erickson, KA | 1 |
| Schroeder, A | 1 |
| Liu, S | 1 |
| Araujo, SV | 1 |
| Spaeth, GL | 1 |
| Katz, LJ | 1 |
| Smith, M | 1 |
| Konno, S | 1 |
| Goger, DG | 1 |
| Fujio, N | 1 |
| Melena, J | 2 |
| Abreu, MM | 1 |
| Kim, YY | 1 |
| Shin, DH | 2 |
| Zalduegui, A | 1 |
| Arcocha, P | 1 |
| Kardasis, CT | 1 |
| Kim, C | 1 |
| Juzych, MS | 1 |
| Hughes, BA | 1 |
| Keole, NS | 1 |
| Green, K | 1 |
| Kim, K | 1 |
| Abelson, MB | 1 |
| Gilbert, CM | 1 |
| Smith, LM | 1 |
6 trials available for verapamil and Intraocular Pressure
| Article | Year |
|---|---|
Comparative study of topical application of timolol and verapamil in patients with glaucoma within 6 months.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Metho | 2009 |
Color Doppler ultrasound analysis of ocular circulation after topical calcium channel blocker.
Topics: Administration, Topical; Adult; Arteries; Blood Circulation; Ciliary Body; Double-Blind Method; Eye; | 1995 |
Lack of effect of calcium channel blockers on open-angle glaucoma.
Topics: Aged; Calcium Channel Blockers; Diltiazem; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middl | 1996 |
Optic nerve head circulation after topical calcium channel blocker.
Topics: Administration, Topical; Adult; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Intra | 1996 |
Topical verapamil and episcleral venous pressure.
Topics: Administration, Topical; Adult; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double | 1998 |
Topical verapamil in glaucoma filtration surgery.
Topics: Administration, Topical; Aged; Calcium Channel Blockers; Chemotherapy, Adjuvant; Chronic Disease; Do | 2001 |
12 other studies available for verapamil and Intraocular Pressure
| Article | Year |
|---|---|
The influence of the calcium channel blocker verapamil on experimental glaucoma.
Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Epinephrine; Glaucoma; Intraocular Pressu | 2004 |
Elevation of intraocular pressure by calcium channel blockers.
Topics: Administration, Oral; Administration, Topical; Animals; Aqueous Humor; Ascorbic Acid; Calcium Channe | 1984 |
[The effects of calcium antagonists on prostaglandin E2 reaction in rabbit eyes].
Topics: Animals; Aqueous Humor; Calcium Channel Blockers; Diltiazem; Dinoprostone; Eye; Eye Proteins; Intrao | 1994 |
Calcium channel blockers in the management of low-tension and open-angle glaucoma.
Topics: Administration, Topical; Animals; Aqueous Humor; Glaucoma, Open-Angle; Half-Life; Humans; Intraocula | 1993 |
The topical application of verapamil and nifedipine lowers intraocular pressure in conscious rabbits.
Topics: Administration, Topical; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Intraocular Press | 1993 |
Calcium channel blockers in the management of low-tension and open-angle glaucoma.
Topics: Administration, Oral; Aged; Aged, 80 and over; Calcium Channel Blockers; Diltiazem; Female; Follow-U | 1993 |
Drug effects on intraocular pressure and vascular flow in the bovine perfused eye using radiolabelled microspheres.
Topics: Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Carteolol; Cattle; Cerium Radioisotopes; | 1995 |
Verapamil increases outflow facility in the human eye.
Topics: Aged; Anterior Eye Segment; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Intr | 1995 |
A complex interaction between topical verapamil and timolol on intraocular pressure in conscious rabbits.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Dose-Respon | 1996 |
Topical verapamil lowers outflow facility in the rabbit eye.
Topics: Administration, Topical; Animals; Aqueous Humor; Calcium Channel Blockers; Female; Intraocular Press | 1999 |
Papaverine and verapamil interaction with prostaglandin E2 and delta9-Tetrahydrocannabinol in the eye.
Topics: Dronabinol; Drug Interactions; Intraocular Pressure; Papaverine; Prostaglandins E; Uvea; Vasomotor S | 1977 |
Sustained reduction of intraocular pressure in humans with the calcium channel blocker verapamil.
Topics: Administration, Topical; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Humans; Intraoc | 1988 |