verapamil has been researched along with Intracranial Aneurysm in 12 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (
| Excerpt | Relevance | Reference |
|---|---|---|
| "High-dose IA verapamil treatment is well-tolerated in the high-risk aneurysmal subarachnoid hemorrhage population that experience severe, symptomatic CVS with good functional outcomes at follow-up." | 8.02 | The clinical impact and safety profile of high-dose intra-arterial verapamil treatment for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Esplin, N; Gigliotti, MJ; Mao, G; Sexton, K, 2021) |
| "According to angiorraphy cerebral vasospasm in acute rupture of an aneurysm is detected in 50-70% of cases, and the risk of ischemia on it's background is 19-46%." | 5.39 | [Intra-arterial injection of verapamil in treatment of cerebral vasospasm in a patient with acute subarachnoid hemorrhage from an aneurysm: case report]. ( Éliava, ShSh; Iakovlev, SB; Lubnin, AIu; Mikeladze, KG; Shekhtman, OD; Tabasaranskiĭ, TF, 2013) |
| "The first results of intracisternal administration of verapamil for the prevention and treatment of cerebral vasospasm (CVS) in patients in the acute period of subarachnoid hemorrhage (SAH) after microsurgical clipping of cerebral aneurysms are presented." | 5.30 | [Intracisternal administration of verapamil for the prevention and treatment of vasospasm in patients after microsurgical treatment of cerebral aneurysms in the acute period of hemorrhage]. ( Baranich, AI; Belousova, OB; Eliava, SS; Gorozhanin, VA; Kheyreddin, AS; Konovalov, AN; Kurdyumova, NV; Mikeladze, KG; Okishev, DN; Pilipenko, YV; Savin, IA; Shekhtman, OD; Spiru, AM; Tabasaransky, TF; Varyukhina, MD; Vinogradov, EV, 2019) |
| "High-dose IA verapamil treatment is well-tolerated in the high-risk aneurysmal subarachnoid hemorrhage population that experience severe, symptomatic CVS with good functional outcomes at follow-up." | 4.02 | The clinical impact and safety profile of high-dose intra-arterial verapamil treatment for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Esplin, N; Gigliotti, MJ; Mao, G; Sexton, K, 2021) |
| " After receiving a nonselective slow infusion of verapamil, the patient developed an episode of extreme hypertension." | 3.75 | Near-complete resolution of angiographic cerebral vasospasm after extreme elevation of mean arterial pressure: case report. ( Dacey, RG; Derdeyn, CP; Diringer, MN; Moran, CJ; Ray, WZ; Zipfel, GJ, 2009) |
| "However, posterior reversible encephalopathy syndrome (PRES) is a hyperperfusion syndrome reported as a rare complication of IH that may confound this picture." | 1.42 | Posterior reversible encephalopathy syndrome with thalamic involvement during vasopressor treatment of vertebrobasilar vasospasm after subarachnoid hemorrhage. ( Dhar, R; Madaelil, TP, 2015) |
| "According to angiorraphy cerebral vasospasm in acute rupture of an aneurysm is detected in 50-70% of cases, and the risk of ischemia on it's background is 19-46%." | 1.39 | [Intra-arterial injection of verapamil in treatment of cerebral vasospasm in a patient with acute subarachnoid hemorrhage from an aneurysm: case report]. ( Éliava, ShSh; Iakovlev, SB; Lubnin, AIu; Mikeladze, KG; Shekhtman, OD; Tabasaranskiĭ, TF, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Pilipenko, YV | 1 |
| Varyukhina, MD | 1 |
| Eliava, SS | 1 |
| Belousova, OB | 1 |
| Savin, IA | 1 |
| Okishev, DN | 1 |
| Mikeladze, KG | 2 |
| Shekhtman, OD | 2 |
| Kheyreddin, AS | 1 |
| Konovalov, AN | 1 |
| Gorozhanin, VA | 1 |
| Spiru, AM | 1 |
| Kurdyumova, NV | 1 |
| Tabasaransky, TF | 1 |
| Baranich, AI | 1 |
| Vinogradov, EV | 1 |
| Mao, G | 1 |
| Gigliotti, MJ | 1 |
| Esplin, N | 1 |
| Sexton, K | 1 |
| Bizilis, JC | 1 |
| Simonin, A | 1 |
| Lind, CR | 1 |
| Pace, J | 1 |
| Nelson, J | 1 |
| Ray, A | 1 |
| Hu, Y | 1 |
| Folzenlogen, Z | 1 |
| Seinfeld, J | 1 |
| Kubes, S | 1 |
| Kumpe, D | 1 |
| Case, D | 1 |
| Roark, C | 1 |
| Éliava, ShSh | 1 |
| Lubnin, AIu | 1 |
| Tabasaranskiĭ, TF | 1 |
| Iakovlev, SB | 1 |
| Chen, SH | 1 |
| Grandhi, R | 1 |
| Deibert, CP | 1 |
| Jovin, TG | 1 |
| Gardner, PA | 1 |
| Ducruet, AF | 1 |
| Madaelil, TP | 1 |
| Dhar, R | 1 |
| Ray, WZ | 1 |
| Moran, CJ | 1 |
| Derdeyn, CP | 1 |
| Diringer, MN | 1 |
| Dacey, RG | 1 |
| Zipfel, GJ | 1 |
| Valença, MM | 1 |
| Andrade-Valença, LP | 1 |
| Martins, C | 1 |
| de Fátima Vasco Aragão, M | 1 |
| Batista, LL | 1 |
| Peres, MF | 1 |
| da Silva, WF | 1 |
| Keuskamp, J | 1 |
| Murali, R | 1 |
| Chao, KH | 1 |
| Handa, J | 1 |
| Shiino, A | 1 |
| Kidooka, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Intra-arterial Vasospasm Trial(iVAST)- A Multi-center Randomized Study[NCT01996436] | Phase 4 | 330 participants (Anticipated) | Interventional | 2016-08-29 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for verapamil and Intracranial Aneurysm
| Article | Year |
|---|---|
[Ca antagonists in neurosurgical practice].
Topics: Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cerebral Infarction; Disease Models, Anim | 1990 |
1 trial available for verapamil and Intracranial Aneurysm
| Article | Year |
|---|---|
[Intracisternal administration of verapamil for the prevention and treatment of vasospasm in patients after microsurgical treatment of cerebral aneurysms in the acute period of hemorrhage].
Topics: Humans; Intracranial Aneurysm; Subarachnoid Hemorrhage; Treatment Outcome; Vasodilator Agents; Vasos | 2019 |
10 other studies available for verapamil and Intracranial Aneurysm
| Article | Year |
|---|---|
The clinical impact and safety profile of high-dose intra-arterial verapamil treatment for cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Aneurysm, Ruptured; Anticonvulsants; Brain Ischemia; Dose-Response Relationship, Drug; Female; Funct | 2021 |
Delayed oculomotor nerve palsy associated with a ruptured anterior communicating aneurysm: Case report.
Topics: Aneurysm, Ruptured; Endovascular Procedures; Female; Humans; Intracranial Aneurysm; Middle Aged; Ocu | 2021 |
Verapamil-induced breakdown of the blood-brain barrier presenting as a transient right middle cerebral artery syndrome.
Topics: Blood-Brain Barrier; Carotid Artery, Internal; Cerebral Angiography; Computed Tomography Angiography | 2017 |
Use of the PulseRider Device in the Treatment of Ruptured Intracranial Aneurysms: A Case Series.
Topics: Abciximab; Adult; Aged; Aneurysm, Ruptured; Calcium Channel Blockers; Cerebral Angiography; Combined | 2019 |
[Intra-arterial injection of verapamil in treatment of cerebral vasospasm in a patient with acute subarachnoid hemorrhage from an aneurysm: case report].
Topics: Acute Disease; Aged; Aneurysm, Ruptured; Female; Humans; Intracranial Aneurysm; Subarachnoid Hemorrh | 2013 |
Coil herniation following intra-arterial verapamil infusion for the treatment of cerebral vasospasm: Case report and literature review.
Topics: Blood Vessel Prosthesis; Carotid Artery, Internal; Hemiplegia; Hernia; Humans; Infusions, Intra-Arte | 2015 |
Posterior reversible encephalopathy syndrome with thalamic involvement during vasopressor treatment of vertebrobasilar vasospasm after subarachnoid hemorrhage.
Topics: Humans; Intracranial Aneurysm; Magnetic Resonance Imaging; Male; Middle Aged; Phenylephrine; Posteri | 2015 |
Near-complete resolution of angiographic cerebral vasospasm after extreme elevation of mean arterial pressure: case report.
Topics: Calcium Channel Blockers; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Fema | 2009 |
Cluster headache and intracranial aneurysm.
Topics: Afferent Pathways; Calcium Channel Blockers; Carotid Artery, Internal; Cerebral Angiography; Cluster | 2007 |
High-dose intraarterial verapamil in the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Heart Rat | 2008 |