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verapamil and Injury, Myocardial Reperfusion

verapamil has been researched along with Injury, Myocardial Reperfusion in 85 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"The administration of verapamil during the reperfusion phase of acute myocardial infarction can reduce the extent and severity of microvessel damage and limit myocardial dysfunction."9.09Early administration of verapamil after thrombolysis in acute anterior myocardial infarction. Effect on left ventricular remodeling and clinical outcome. VAMI Study Group. Verapamil Acute Myocardial Infarction. ( Biasco, MG; Boni, L; Brigiani, MS; Iliceto, S; Marangelli, V; Memmola, C; Rizzon, P; Scrutinio, D, 2000)
" In this study, we evaluated the ability of HO-4038, an N-hydroxypiperidine derivative of verapamil, on the modulation of myocardial tissue oxygenation (Po(2)), I/R injury, and key signaling molecules involved in cardioprotection in an in vivo rat model of acute myocardial infarction (MI)."7.75Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction. ( Bognar, B; Carnes, CA; Hideg, K; Kálai, T; Khan, M; Kuppusamy, P; Mohan, IK; Selvendiran, K; Sridhar, A; Wisel, S, 2009)
"During the ischemic period, the low (clinically relevant) dose of mibefradil prevented the fall of the ventricular fibrillation threshold, without depressing the maximal rate of pressure development of the left ventricle (LVmax dP/dt)."7.70Effects of mibefradil, a novel calcium channel blocking agent with T-type activity, in acute experimental myocardial ischemia: maintenance of ventricular fibrillation threshold without inotropic compromise. ( Hofmann, D; McCarthy, J; Muller, CA; Opie, LH; Peisach, M; Pineda, CA, 1998)
"This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion."7.70[Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999)
"The authors evaluated the effects of verapamil (Ve) and magnesium sulfate (Mg) on the electrophysiologic changes induced in dogs during acute myocardial ischemia and following reperfusion."7.69Effects of verapamil and magnesium sulfate on electrophysiologic changes during acute myocardial ischemia and following reperfusion in dogs: comparative effects of administration by intravenous and coronary sinus retroperfusion routes. ( Bando, S; Yamamoto, K, 1996)
"1."5.29Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs. ( Boulanger, CM; Kirchengast, M; Lee, JJ; Vanhoutte, PM, 1996)
"Arrhythmias were associated with prolongation of transmural conduction time (CT) and abbreviation of endocardial effective refractory period."5.28Verapamil prevents slowing of transmural conduction and suppresses arrhythmias in an isolated guinea pig ventricular model of ischemia and reperfusion. ( Ferrier, GR; Li, GR, 1992)
"Intracoronary verapamil restored myocardial perfusion in patients with angiographic no-reflow after PCI and lead to better functional recovery after acute myocardial infarction."5.12The effect of verapamil on the restoration of myocardial perfusion and functional recovery in patients with angiographic no-reflow after primary percutaneous coronary intervention. ( Baden, M; Fujitaka, K; Iwasaka, T; Nakamura, S; Sugiura, T; Tsuka, Y; Umemura, S; Yoshida, S, 2006)
"The administration of verapamil during the reperfusion phase of acute myocardial infarction can reduce the extent and severity of microvessel damage and limit myocardial dysfunction."5.09Early administration of verapamil after thrombolysis in acute anterior myocardial infarction. Effect on left ventricular remodeling and clinical outcome. VAMI Study Group. Verapamil Acute Myocardial Infarction. ( Biasco, MG; Boni, L; Brigiani, MS; Iliceto, S; Marangelli, V; Memmola, C; Rizzon, P; Scrutinio, D, 2000)
" In this study, we evaluated the ability of HO-4038, an N-hydroxypiperidine derivative of verapamil, on the modulation of myocardial tissue oxygenation (Po(2)), I/R injury, and key signaling molecules involved in cardioprotection in an in vivo rat model of acute myocardial infarction (MI)."3.75Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction. ( Bognar, B; Carnes, CA; Hideg, K; Kálai, T; Khan, M; Kuppusamy, P; Mohan, IK; Selvendiran, K; Sridhar, A; Wisel, S, 2009)
" Mibefradil was compared with (+/-)-verapamil for effects on ischaemia- and reperfusion-induced ventricular fibrillation (VF), and the role of ischaemia-selective L-channel block was examined."3.70Inadequate ischaemia-selectivity limits the antiarrhythmic efficacy of mibefradil during regional ischaemia and reperfusion in the rat isolated perfused heart. ( Curtis, MJ; Farkas, A; Qureshi, A, 1999)
"This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion."3.70[Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999)
"During the ischemic period, the low (clinically relevant) dose of mibefradil prevented the fall of the ventricular fibrillation threshold, without depressing the maximal rate of pressure development of the left ventricle (LVmax dP/dt)."3.70Effects of mibefradil, a novel calcium channel blocking agent with T-type activity, in acute experimental myocardial ischemia: maintenance of ventricular fibrillation threshold without inotropic compromise. ( Hofmann, D; McCarthy, J; Muller, CA; Opie, LH; Peisach, M; Pineda, CA, 1998)
"Contrast-enhanced magnetic resonance (MR) imaging was used to detect and quantify the extent of myocardial injury after a brief coronary occlusion and reperfusion in response to verapamil treatment in a rat model of left ventricular hypertrophy (LVH)."3.69Verapamil reduces the size of reperfused ischemically injured myocardium in hypertrophied rat hearts as assessed by magnetic resonance imaging. ( Derugin, N; Higgins, CB; Lauerma, K; Saeed, M; Wendland, MF; Yu, KK, 1996)
"The authors evaluated the effects of verapamil (Ve) and magnesium sulfate (Mg) on the electrophysiologic changes induced in dogs during acute myocardial ischemia and following reperfusion."3.69Effects of verapamil and magnesium sulfate on electrophysiologic changes during acute myocardial ischemia and following reperfusion in dogs: comparative effects of administration by intravenous and coronary sinus retroperfusion routes. ( Bando, S; Yamamoto, K, 1996)
"Combination of chlorpromazine (CPZ) and verapamil (Ver) was found to decrease the incidence of ventricular arrhythmias and ventricular fibrillation induced by myocardial ischemia and reperfusion, lower serum creatine phosphokinase (CPK) and decrease the content of malondialdehyde (MDA) in heart tissue homogenate especially in mitochondria; and increase the phospholipid content and the phospholipid/cholesterol ratio; and decrease the myocardial "cell calcium" content in the reperfused area."3.68[Protective effects of combination of chlorpromazine and verapamil on ischemia-reperfusion induced injury in rat myocardium]. ( Deng, Y; Zhang, ZS, 1993)
" The action of IHC-72 against aconitine induced arrhythmia was similar to that of Lid but stronger than that of Ver in anesthetized rats."3.68[Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil]. ( Ji, GJ; Liu, DQ; Sheng, BH; Zhao, DH, 1992)
"The aim of the present study was to define the protective effects of verapamil and nifedipine on mechanical performance and energy and substrate metabolism of the postischemically reperfused myocardium in a chronic pressure overload cardiac hypertrophy model."3.68Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy. ( Buser, PT; Higgins, CB; Wagner, S; Wikman-Coffelt, J; Wu, S, 1991)
"The effects of three calcium antagonists (diltiazem, verapamil, and nifedipine) on reperfusion-induced arrhythmias were compared in a conscious rat preparation with coronary artery occlusion and implanted electrocardiogram limb electrodes."3.67Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS; Mitani, A, 1989)
"With verapamil there is a small tendency for a reduction in reinfarction, with nifedipine a clear worsening, and with diltiazem a reduction almost reaching statistical significance."2.38Protective effects of calcium antagonists against ischaemia and reperfusion damage. ( Ferrari, R; Visioli, O, 1991)
"Verapamil or saline was given into the LAD artery either at the time the coronary artery was occluded (ie, during acute severe ischemia or during the reperfusion period)."1.34Calcium antagonist verapamil and reperfusion injury of the heart. ( Coetzee, A; Conradie, S, 2007)
"To study the influence of acute renal failure in ischemic-reperfusion injury on the heart, we used isolated Langendorff's hearts of guinea pigs with gentamicin-induced acute renal failure."1.32Mibefradil is more effective than verapamil for restoring post-ischemic function of isolated hearts of guinea pigs with acute renal failure. ( Budihna, MV; Grasic Kuhar, C; Pleskovic, RZ, 2004)
"Infarct, arrhythmia, heart rate and coronary artery flow were determined in hearts treated with vehicle, RST extract, Tet, Fan, or verapamil."1.31Cardiac effects of the extract and active components of radix stephaniae tetrandrae. II. Myocardial infarct, arrhythmias, coronary arterial flow and heart rate in the isolated perfused rat heart. ( Chen, CF; Pang, KT; Shan, J; Wang, GY; Wong, TM; Wu, S; Yu, XC, 2001)
"Pretreatment with lidocaine (5 mg/kg), verapamil (0."1.30Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx. ( Dai, DZ; De Clerck, F; Lu, HR; Remeysen, P; Saels, A; Yang, P, 1999)
"Diltiazem was the less effective drug on both left ventricular hemodynamics and coronary circulation."1.30Calcium-channel blockers preserve coronary endothelial reactivity after ischemia-reperfusion. ( Buluran, J; Cartier, R; Dagenais, F; Hollmann, C, 1997)
"In nexopamil-treated pigs, this was paralleled by reduced release of creatine kinase (CK) into coronary venous blood."1.29Protection of reperfused ischemic pig myocardium by nexopamil, a new combined Ca2+ and serotonin antagonist. ( Braun, M; Hohlfeld, T; Schrör, K; Strobach, H, 1994)
"Pretreatment with coenzyme Q10 given intraperitoneally improved aortic flow, cardiac output, stroke volume, coronary flow, and heart rate."1.29Improvement of cardiac function impaired by repeated ischemic arrests in isolated rat hearts. ( Ali, K; Fukaya, Y; Furukawa, Y; Morimoto, M, 1993)
"Thus verapamil post-treatment can prevent reperfusion-induced myocardial injury but functional recovery may be delayed due to the drug's inherent direct myocardial depressant effect."1.29Effect of verapamil post-treatment in myocardial reperfusion injury. ( Gupta, YK; Manchanda, SC; Maulik, MG; Maulik, SK; Reddy, KS; Seth, SD, 1993)
" R56865 was given before ischemia and with the onset of reperfusion, applying different dosing schedules, including an initial loading dose."1.29R56865 is antifibrillatory in reperfused ischemic guinea-pig hearts, even when given only during reperfusion. ( Guttmann, I; Mozes, A; Scheufler, E; Wilffert, B, 1995)
"1."1.29Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs. ( Boulanger, CM; Kirchengast, M; Lee, JJ; Vanhoutte, PM, 1996)
"Arrhythmias were associated with prolongation of transmural conduction time (CT) and abbreviation of endocardial effective refractory period."1.28Verapamil prevents slowing of transmural conduction and suppresses arrhythmias in an isolated guinea pig ventricular model of ischemia and reperfusion. ( Ferrier, GR; Li, GR, 1992)
"Pretreatment with verapamil to reperfusion hearts decreased MPO activity to 4."1.28[Neutrophil infiltration in ischemic porcine myocardium and protective effect of verapamil]. ( Guo, ZG; Luo, WS; Tang, XL, 1990)
"Verapamil cardioplegia was still better than Salvia miltiorrhiza Bunge."1.28[Experimental study on myocardial protection with verapamil and salvia miltiorrhiza Bunge cardioplegia]. ( Zhu, P, 1990)
"DESIGN - Ventricular arrhythmias were studied in isolated rat hearts (n = 8-15 per experiment) subjected to regional ischaemia and treated with various free radical scavengers and spin trap agents."1.28Reperfusion damage: free radicals mediate delayed membrane changes rather than early ventricular arrhythmias. ( Coetzee, WA; Dennis, SC; Opie, LH; Owen, P; Saman, S, 1990)
"4."1.28Effects of verapamil on ischaemia-induced impairment of ATP-dependent calcium extrusion in rat heart sarcolemma. ( Goddijn, MM; Haas, M; Punt, NC; van Amsterdam, FT; Zaagsma, J, 1989)

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-199012 (14.12)18.7374
1990's50 (58.82)18.2507
2000's16 (18.82)29.6817
2010's7 (8.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nihro, Y1
Sogawa, S1
Izumi, A1
Sasamori, A1
Sudo, T1
Miki, T1
Matsumoto, H1
Satoh, T1
Jiang, M1
Wang, Q1
Chen, J1
Wang, Y1
Fan, G1
Zhu, Y1
Sun, XQ1
Chen, S1
Wang, LF1
Chen, ZW1
Xiong, F1
Wang, H1
Feng, Y1
Li, Y1
Hua, X1
Pang, X1
Zhang, S1
Song, L1
Zhang, Y1
Gu, N1
Lishmanov, YB1
Maslov, LN1
Mukhomedzyanov, AV1
Mohan, IK2
Khan, M2
Wisel, S1
Selvendiran, K1
Sridhar, A2
Carnes, CA2
Bognar, B1
Kálai, T2
Hideg, K2
Kuppusamy, P2
Yu, W2
Wang, JJ2
Gan, WY1
Lin, GS2
Huang, CX2
Yi, XQ1
Li, T1
Wang, JR1
Wong, VK1
Luo, P1
Wong, IY1
Jiang, ZH1
Liu, L1
Zhou, H1
Wen, ZY1
Ouyang, JP1
Huang, H1
Ronson, RS1
Puskas, JD1
Thourani, VH1
Velez, DA1
Bufkin, BL1
Glass, J1
Guyton, RA1
Vinten-Johansen, J1
Shen, YL1
Chen, YY1
Wu, XD1
Bruce, IC1
Xia, Q1
Yu, XC2
Wu, S3
Chen, CF2
Pang, KT2
Wong, TM2
Grasic Kuhar, C2
Budihna, MV2
Pleskovic, RZ1
Reffelmann, T1
Kloner, RA1
Asemu, G1
Dhalla, NS1
Tappia, PS1
Alfayoumi, F1
Srinivasan, V1
Geller, M1
Gradman, A1
Umemura, S1
Nakamura, S1
Sugiura, T1
Tsuka, Y1
Fujitaka, K1
Yoshida, S2
Baden, M1
Iwasaka, T1
Kazanskaia, GM1
Volkov, AM1
D'iakonitsa, TM1
Zhdanov, GP1
Coetzee, A1
Conradie, S1
Mandal, R1
Kutala, VK1
Varadharaj, S1
Shan, D1
Marchase, RB1
Chatham, JC1
Hohlfeld, T1
Braun, M1
Strobach, H1
Schrör, K1
Richard, V1
Tron, C1
Blanc, T1
Thuillez, C1
Ken, N1
Katsuo, K1
Nagao, K1
Yanagida, S2
Ohsuzu, F2
Sakata, N2
Maie, S1
Akanuma, M1
Takayama, E1
Hayashi, K1
Aosaki, N1
Nakamura, H2
Ji, GJ2
Zhang, JZ1
Liu, DQ2
Zhao, DH2
Sheng, BH2
Deng, Y1
Zhang, ZS1
Zhou, J1
Xuan, B1
Li, DX1
Meng, HP1
Maddaford, TG1
Pierce, GN1
Curtis, MJ2
Garlick, PB1
Ridley, PD1
Ali, K1
Morimoto, M1
Fukaya, Y1
Furukawa, Y1
Maulik, SK1
Seth, SD1
Manchanda, SC1
Reddy, KS1
Gupta, YK1
Maulik, MG1
Scheufler, E1
Mozes, A1
Guttmann, I1
Wilffert, B1
Lauerma, K1
Saeed, M1
Wendland, MF1
Derugin, N2
Yu, KK1
Higgins, CB3
Chagas, AC2
Pileggi, F2
Lopes, EA1
Da-Luz, PL2
Yamamoto, K1
Bando, S1
Nearing, BD1
Hutter, JJ1
Verrier, RL1
Lee, JJ1
Boulanger, CM1
Kirchengast, M1
Vanhoutte, PM1
Dagenais, F1
Cartier, R1
Hollmann, C1
Buluran, J1
Muller, CA2
Opie, LH3
McCarthy, J2
Hofmann, D1
Pineda, CA2
Peisach, M1
Vrbjar, N1
Zöllner, S1
Haseloff, RF1
Pissarek, M1
Blasig, IE1
Kraljevic, V1
Lu, HR1
Yang, P1
Remeysen, P1
Saels, A1
Dai, DZ1
De Clerck, F1
Di Napoli, P1
Ranalli, G1
Di Crecchio, A1
Taccardi, AA1
Ausiello, A1
Di Muzio, M1
Barsotti, A1
Farkas, A1
Qureshi, A1
Furuya, M1
Yoshida, K1
Marangelli, V1
Memmola, C1
Brigiani, MS1
Boni, L1
Biasco, MG1
Scrutinio, D1
Iliceto, S1
Rizzon, P1
Wang, GY1
Shan, J1
Huddleston, CB1
Wareing, TH1
Boucek, RJ1
Hammon, JW1
Li, GR1
Ferrier, GR1
Soncul, H1
Gökgöz, L1
Karasu, C1
Ayrancioğlu, K1
Ersöz, A1
Altan, M1
Yener, A1
Yoshikawa, T1
Akaishi, M1
Ikeda, F1
Handa, S1
Nakamura, Y1
Vandeplassche, G1
Thoné, F1
Borgers, M1
Sullivan, AT1
Baker, DJ1
Drew, GM1
Ferrari, R1
Visioli, O1
Nayler, WG1
Buser, PT2
Wagner, S2
Wikman-Coffelt, J2
Chung, JK1
Lim, SM1
Lee, MC1
Koh, CS1
Lee, M1
Seo, JW1
Zhuang, XX1
Shvilkin, AV1
Afonskaia, NI1
Sadretdinov, SM1
Cherpachenko, NM1
Levitskiĭ, DO1
Ruda, MIa1
Yamamoto, F1
Yamamoto, H1
Ichikawa, H1
Takahashi, A1
Tanaka, K1
Kosakai, Y1
Yagihara, T1
Fujita, T1
Mjøs, OD1
Ichihara, K1
Fellenius, E1
Myrmel, T1
Neely, JR1
Huang, TF1
Huang, LL1
Luo, WS1
Guo, ZG1
Tang, XL1
Silveira, MC1
von Planta, M1
Weil, MH1
Gazmuri, RJ1
Ritz, MA1
Rackow, EC1
Zhu, P2
Rotevatn, S1
Greve, G1
Oksendal, AN1
Jynge, P1
Conorev, EA1
Rudnev, DV3
Conorev, LA1
Polumiskov, VY1
Golikov, AP2
Coetzee, WA1
Owen, P1
Dennis, SC1
Saman, S1
Mrak, RE1
Carry, MM1
Murphy, ML2
Peng, CF2
Straub, KD2
Pichigin, VV1
Konorev, EA1
Konorev, LA1
Polumiskov, VIu1
Klein, HH1
Pich, S1
Lindert, S1
Nebendahl, K1
Warneke, G1
Kreuzer, H1
Wu, ST1
Parmley, WW1
Shirakura, R1
Hirose, H1
Matsuda, H1
Nakano, S1
Nakata, S1
Ohtani, M1
Kawaguti, A1
Miyagawa, S1
Takami, H1
Naka, Y1
Kinoshita, K1
Mitani, A1
Hearse, DJ1
Braimbridge, MV1
Manning, AS1
Bratus', VV1
Sergienko, OV1
Bezus'ko, AG1
Shavaran, SS1
van Amsterdam, FT1
Goddijn, MM1
Haas, M1
Punt, NC1
Zaagsma, J1
Kucharská, J1
Gvozdjáková, A1
Gvozdják, J1
Odom, H1
Davis, JL1

Reviews

4 reviews available for verapamil and Injury, Myocardial Reperfusion

ArticleYear
The no-reflow phenomenon: epidemiology, pathophysiology, and therapeutic approach.
    Reviews in cardiovascular medicine, 2005,Spring, Volume: 6, Issue:2

    Topics: Adenosine; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Echocardiography; Hum

2005
Myocardial protection in the occlusion/reperfusion dog model: the role of ischemic necrosis vs reperfusion injury.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1995, Volume: 28, Issue:9

    Topics: Animals; Coronary Vessels; Deferoxamine; Disease Models, Animal; Dogs; Free Radicals; Iron; Myocardi

1995
Protective effects of calcium antagonists against ischaemia and reperfusion damage.
    Drugs, 1991, Volume: 42 Suppl 1

    Topics: Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Humans; Myocardial Reperfusion Injur

1991
Basic mechanisms involved in the protection of the ischaemic myocardium. The role of calcium antagonists.
    Drugs, 1991, Volume: 42 Suppl 2

    Topics: Calcium; Calcium Channel Blockers; Coronary Disease; Humans; Myocardial Reperfusion Injury; Myocardi

1991

Trials

2 trials available for verapamil and Injury, Myocardial Reperfusion

ArticleYear
The effect of verapamil on the restoration of myocardial perfusion and functional recovery in patients with angiographic no-reflow after primary percutaneous coronary intervention.
    Nuclear medicine communications, 2006, Volume: 27, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Humans; Male; Myocardial Infarction; Myocardial Reperfusion In

2006
Early administration of verapamil after thrombolysis in acute anterior myocardial infarction. Effect on left ventricular remodeling and clinical outcome. VAMI Study Group. Verapamil Acute Myocardial Infarction.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2000, Volume: 1, Issue:5

    Topics: Calcium Channel Blockers; Double-Blind Method; Echocardiography; Female; Humans; Male; Middle Aged;

2000

Other Studies

79 other studies available for verapamil and Injury, Myocardial Reperfusion

ArticleYear
3-O-alkylascorbic acids as free radical quenchers. 3. Protective effect on coronary occlusion-reperfusion induced arrhythmias in anesthetized rats.
    Journal of medicinal chemistry, 1992, May-01, Volume: 35, Issue:9

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Ascorbic Acid; Blood Pressure; Fr

1992
Comparative metabonomics of Wenxin Keli and Verapamil reveals differential roles of gluconeogenesis and fatty acid β-oxidation in myocardial injury protection.
    Scientific reports, 2017, 08-18, Volume: 7, Issue:1

    Topics: Animals; Biomarkers; Cardiotonic Agents; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Acids;

2017
Total flavones of Rhododendron simsii Planch flower protect isolated rat heart from ischaemia-reperfusion injury and its mechanism of UTR-RhoA-ROCK pathway inhibition.
    The Journal of pharmacy and pharmacology, 2018, Volume: 70, Issue:12

    Topics: Animals; Coronary Circulation; Creatine Kinase, MB Form; Dose-Response Relationship, Drug; Female; F

2018
Cardioprotective activity of iron oxide nanoparticles.
    Scientific reports, 2015, Feb-26, Volume: 5

    Topics: Animals; Cardiotonic Agents; Cells, Cultured; Drug Evaluation, Preclinical; Female; Ferric Compounds

2015
Role of β-Adrenoceptors and L-Type Ca(2+)-Channels in the Mechanism of Reperfusion-Induced Heart Injury.
    Bulletin of experimental biology and medicine, 2016, Volume: 161, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Calcium Channels, L-Type; Male; Myocardial Reperfusion Injury;

2016
Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Blotting, Western; Calcium Channel Blockers; Calcium

2009
[Effects of verapamil preconditioning on cardiac function in vitro and intracellular free Ca2+ and L-type calcium current in rat cardiomyocytes post ischemia-reperfusion injury].
    Zhonghua xin xue guan bing za zhi, 2010, Volume: 38, Issue:3

    Topics: Animals; Calcium; Calcium Channels, L-Type; Ischemic Preconditioning, Myocardial; Myocardial Reperfu

2010
Total ginsenosides increase coronary perfusion flow in isolated rat hearts through activation of PI3K/Akt-eNOS signaling.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:13

    Topics: Animals; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells

2010
[Influences and mechanism of verapamil on ischemia/reperfusion injury in cardiomyocytes of streptozotocin-induced diabetes mellitus rats].
    Zhonghua yi xue za zhi, 2010, Nov-16, Volume: 90, Issue:42

    Topics: Animals; Calcium; Calcium Channels, L-Type; Diabetes Mellitus, Experimental; Male; Myocardial Reperf

2010
Controlled intermittent asystole cardiac therapy induced by pharmacologically potentiated vagus nerve stimulation in normal and hibernating myocardium.
    The Annals of thoracic surgery, 2003, Volume: 75, Issue:6

    Topics: Animals; Coronary Artery Bypass; Coronary Circulation; Coronary Stenosis; Creatine Kinase; Dogs; Dru

2003
Activation of mitochondrial ATP-sensitive potassium channels delays ischemia-induced cellular uncoupling in rat heart.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:1

    Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Diazoxide; Hydroxy Acids; Ion Channel Gating; Ische

2004
Antihypertensive and anti-arrhythmic effects of an extract of Radix Stephaniae Tetrandrae in the rat.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:1

    Topics: Alkaloids; Animals; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Benzylisoquinolines; Calcium

2004
Mibefradil is more effective than verapamil for restoring post-ischemic function of isolated hearts of guinea pigs with acute renal failure.
    European journal of pharmacology, 2004, Mar-19, Volume: 488, Issue:1-3

    Topics: Acute Kidney Injury; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Ca

2004
Effects of adenosine and verapamil on anatomic no-reflow in a rabbit model of coronary artery occlusion and reperfusion.
    Journal of cardiovascular pharmacology, 2004, Volume: 43, Issue:4

    Topics: Adenosine; Animals; Blood Pressure; Coronary Disease; Coronary Vasospasm; Disease Models, Animal; Ma

2004
Inhibition of PLC improves postischemic recovery in isolated rat heart.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:6

    Topics: Animals; Calcium; Calcium Channel Blockers; Estrenes; Isoenzymes; Male; Myocardial Reperfusion Injur

2004
[Endothelium of myocardium microvessel under conditions of hypothermia, ischemia, reperfusion and pharmaco-cold cardioplegia with calcium antagonist].
    Tsitologiia, 2005, Volume: 47, Issue:1

    Topics: Calcium Channel Blockers; Cardioplegic Solutions; Coronary Vessels; Endothelium, Vascular; Heart Atr

2005
Calcium antagonist verapamil and reperfusion injury of the heart.
    Journal of cardiothoracic and vascular anesthesia, 2007, Volume: 21, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Coronary Circulation; Myocardial Ischemia

2007
N-hydroxy-pyrroline modification of verapamil exhibits antioxidant protection of the heart against ischemia/reperfusion-induced cardiac dysfunction without compromising its calcium antagonistic activity.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Free Radical Scavengers; In

2007
Overexpression of TRPC3 increases apoptosis but not necrosis in response to ischemia-reperfusion in adult mouse cardiomyocytes.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:3

    Topics: Acrylates; Animals; Apoptosis; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium

2008
Protection of reperfused ischemic pig myocardium by nexopamil, a new combined Ca2+ and serotonin antagonist.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:6

    Topics: Animals; Blood Platelets; Calcium Channel Blockers; Creatine Kinase; Diastole; Epoprostenol; Female;

1994
Infarct size-limiting properties of Ro 40-5967, a novel nondihydropyridine calcium channel, in anesthetized rats: comparison with verapamil.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:4

    Topics: Anesthesia; Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Heart Rate; Hemodynam

1995
[Myocardial reperfusion injury with coronary thrombolytic therapy--clinical and experimental studies].
    Japanese circulation journal, 1993, Volume: 57 Suppl 4

    Topics: Animals; Calcium; Dogs; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Ne

1993
Protective effects of verapamil and adenosine treatment on high energy phosphate metabolism in ischemic and reperfused myocardium.
    Japanese heart journal, 1994, Volume: 35, Issue:4

    Topics: Adenosine; Animals; Energy Metabolism; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; M

1994
Protective effects of 3,6-dimethylamino-dibenzopyriodonium edetate on global ischemia reperfused isolated rat hearts.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Calcium; Coronary Circulation; Creatine Kinase; Edetic Acid; In Vit

1993
[Protective effects of combination of chlorpromazine and verapamil on ischemia-reperfusion induced injury in rat myocardium].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:8

    Topics: Animals; Chlorpromazine; Drug Therapy, Combination; Female; Male; Mitochondria, Heart; Myocardial Re

1993
Effects of tetrahydroberberine on ischemic and reperfused myocardium in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Berberine; Berberine Alkaloids; In Vitro Techniques; Male; Malondia

1993
Effect of amiloride and selected analogues on postischemic recovery of cardiac contractile function.
    The American journal of physiology, 1993, Volume: 264, Issue:6 Pt 2

    Topics: Amiloride; Animals; Carrier Proteins; Coronary Disease; Creatine Kinase; Male; Myocardial Contractio

1993
Anion manipulation, a novel antiarrhythmic approach: mechanism of action.
    Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:4

    Topics: Animals; Anions; Blood Pressure; Bromides; Chlorides; Coronary Circulation; Cyclic AMP; Cyclic GMP;

1993
Improvement of cardiac function impaired by repeated ischemic arrests in isolated rat hearts.
    The Annals of thoracic surgery, 1993, Volume: 55, Issue:4

    Topics: Animals; Aorta; Bicarbonates; Calcium Chloride; Cardiac Output; Cardioplegic Solutions; Coenzymes; C

1993
Effect of verapamil post-treatment in myocardial reperfusion injury.
    Indian journal of experimental biology, 1993, Volume: 31, Issue:2

    Topics: Adenosine Triphosphate; Animals; Creatine Kinase; Depression, Chemical; Dogs; Myocardial Contraction

1993
R56865 is antifibrillatory in reperfused ischemic guinea-pig hearts, even when given only during reperfusion.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzothiazoles; Calcium; Calcium Channel Block

1995
Verapamil reduces the size of reperfused ischemically injured myocardium in hypertrophied rat hearts as assessed by magnetic resonance imaging.
    American heart journal, 1996, Volume: 131, Issue:1

    Topics: Animals; Aorta, Abdominal; Calcium Channel Blockers; Coloring Agents; Contrast Media; Disease Models

1996
Effects of verapamil and magnesium sulfate on electrophysiologic changes during acute myocardial ischemia and following reperfusion in dogs: comparative effects of administration by intravenous and coronary sinus retroperfusion routes.
    Angiology, 1996, Volume: 47, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Vessels; Dogs; Electrophysiology

1996
Potent antifibrillatory effect of combined blockade of calcium channels and 5-HT2 receptors with nexopamil during myocardial ischemia and reperfusion in dogs: comparison to diltiazem.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; El

1996
Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs.
    General pharmacology, 1996, Volume: 27, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Coronary Vasospasm; Dog

1996
Calcium-channel blockers preserve coronary endothelial reactivity after ischemia-reperfusion.
    The Annals of thoracic surgery, 1997, Volume: 63, Issue:4

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Diltiazem; Dose-Response

1997
Effects of mibefradil, a novel calcium channel blocking agent with T-type activity, in acute experimental myocardial ischemia: maintenance of ventricular fibrillation threshold without inotropic compromise.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:1

    Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electrocardiogr

1998
PBN spin trapping of free radicals in the reperfusion-injured heart. Limitations for pharmacological investigations.
    Molecular and cellular biochemistry, 1998, Volume: 186, Issue:1-2

    Topics: Animals; Antioxidants; Arrhythmias, Cardiac; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy;

1998
Combination of a calcium antagonist, verapamil, with an angiotensin converting enzyme inhibitor, trandolapril, in experimental myocardial ischemia and reperfusion: antiarrhythmic and hemodynamic effects of chronic oral pretreatment.
    Cardiovascular drugs and therapy, 1998, Volume: 12, Issue:5

    Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Cal

1998
Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx.
    European journal of pharmacology, 1999, Jan-22, Volume: 365, Issue:2-3

    Topics: Amiloride; Anesthesia; Animals; Arrhythmias, Cardiac; Benzothiazoles; Blood Pressure; Calcium; Calci

1999
[The effects of verapamil on the postischemic changes in the coronary microcirculation: the role of nitric oxide].
    Cardiologia (Rome, Italy), 1999, Volume: 44, Issue:7

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; In Vitro Techniques; Male; Microcirculation

1999
Inadequate ischaemia-selectivity limits the antiarrhythmic efficacy of mibefradil during regional ischaemia and reperfusion in the rat isolated perfused heart.
    British journal of pharmacology, 1999, Volume: 128, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channel

1999
[Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:10

    Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disease Models, Animal; Myocardial Ischem

1999
Effects of mibefradil and verapamil on ischemic-reperfusion in the hearts of guinea pigs with acute renal failure.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:5 Suppl

    Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Coronary Circulation; Female; Guinea Pigs; L

2000
Cardiac effects of the extract and active components of radix stephaniae tetrandrae. II. Myocardial infarct, arrhythmias, coronary arterial flow and heart rate in the isolated perfused rat heart.
    Life sciences, 2001, May-11, Volume: 68, Issue:25

    Topics: Alkaloids; Animals; Arrhythmias, Cardiac; Benzylisoquinolines; Calcium Channel Blockers; Coronary Ci

2001
[Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:6

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Edetic Acid; Female; Guinea Pigs;

1992
Response of the hypertrophied left ventricle to global ischemia. Comparison of hyperkalemic cardioplegic solution with and without verapamil.
    The Journal of thoracic and cardiovascular surgery, 1992, Volume: 103, Issue:5

    Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Cardioplegic Solutions; Cardiopulmonary Bypass; Dogs;

1992
Verapamil prevents slowing of transmural conduction and suppresses arrhythmias in an isolated guinea pig ventricular model of ischemia and reperfusion.
    Circulation research, 1992, Volume: 70, Issue:4

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Electrocardiography; Guinea Pigs; Heart Conduction

1992
Comparison of potassium and adenosine cardioplegia with or without verapamil in the isolated guinea pig heart.
    General pharmacology, 1992, Volume: 23, Issue:1

    Topics: Adenosine; Animals; Cardioplegic Solutions; Guinea Pigs; Heart Arrest, Induced; Heart Rate; Male; My

1992
Postischaemic hypercontraction is enhanced in ischaemically injured canine myocardium.
    Cardiovascular research, 1992, Volume: 26, Issue:4

    Topics: Animals; Calcium; Coronary Disease; Disease Models, Animal; Dogs; Myocardial Contraction; Myocardial

1992
Protective effects of R 56 865 against ischemic damage in the isolated rabbit heart.
    European journal of pharmacology, 1991, Sep-17, Volume: 202, Issue:2

    Topics: Animals; Benzothiazoles; Calcium; Calcium Channels; Cell Death; Coronary Disease; Female; Hemodynami

1991
Effect of calcium channel blocking agents on infarct size after ischaemia-reperfusion in anaesthetised pigs: relationship between cardioprotection and cardiodepression.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:5

    Topics: Animals; Aspirin; Coronary Vessels; Depression, Chemical; Heart; Hemodynamics; Injections, Intra-Art

1991
Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 10

    Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Cardiomegaly; Energy Metabolism; Hyperten

1991
Evaluation of the protective effect of verapamil on reperfusion injury by 111In anticardiac myosin antibody in canine myocardial infarction.
    Annals of nuclear medicine, 1991, Volume: 5, Issue:3

    Topics: Animals; Dogs; Evaluation Studies as Topic; Indium Radioisotopes; Myocardial Infarction; Myocardial

1991
[Protective effect of Angelica injection on arrhythmia during myocardial ischemia reperfusion in rat].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991, Volume: 11, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Drugs, Chinese Herbal; Female; Injections, Intraperitoneal; Male; Myo

1991
[Effects of verapamil and nitroglycerin on experimental occlusion- reperfusion-induced myocardial infarction in rabbits].
    Kardiologiia, 1991, Volume: 31, Issue:1

    Topics: Animals; Coronary Vessels; Disease Models, Animal; Drug Evaluation, Preclinical; Ligation; Male; Myo

1991
The effects of several pharmacologic agents upon postischemic recovery.
    Cardiovascular drugs and therapy, 1991, Volume: 5 Suppl 2

    Topics: Animals; Calcium; Cardioplegic Solutions; Coenzymes; Creatine Kinase; Gabexate; Guanidines; In Vitro

1991
Fatty acids suppress recovery of heart function after hypothermic perfusion.
    The Annals of thoracic surgery, 1991, Volume: 52, Issue:4

    Topics: Acyl Coenzyme A; Adenosine Triphosphate; Animals; Calcium; Carnitine; Coronary Circulation; Fatty Ac

1991
Drug effects on myocardial ischemia- and reperfusion-induced arrhythmias in anesthetized rats.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1991, Volume: 15, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Aspirin; Coronary Disease; Male; Mannitol; Myocardial Reperfusion Inj

1991
[Neutrophil infiltration in ischemic porcine myocardium and protective effect of verapamil].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:5

    Topics: Animals; Female; Leukocyte Count; Male; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Pero

1990
Myocardial protection by verapamil and reperfusion following coronary occlusion.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1990, Volume: 23, Issue:3-4

    Topics: Animals; Blood Pressure; Dogs; Heart Rate; Myocardial Infarction; Myocardial Reperfusion; Myocardial

1990
Calcium-entry blockers during porcine cardiopulmonary resuscitation.
    Clinical science (London, England : 1979), 1990, Volume: 78, Issue:2

    Topics: Animals; Blood Pressure; Diltiazem; Disease Models, Animal; Heart Arrest; Hydrogen-Ion Concentration

1990
[Experimental study on myocardial protection with verapamil and salvia miltiorrhiza Bunge cardioplegia].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1990, Volume: 28, Issue:1

    Topics: Animals; Calcium Channels; Cardioplegic Solutions; Cardiopulmonary Bypass; Dogs; Drug Combinations;

1990
Tissue protection by verapamil in the calcium paradox.
    Scandinavian journal of clinical and laboratory investigation, 1990, Volume: 50, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Chloride; Creatine Kinase;

1990
Pharmacologic modifications of reperfusion arrhythmias in the dog in vivo: possible relation to limitation of the extent of infarction.
    International journal of cardiology, 1990, Volume: 28, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Butylated Hydroxytoluene; Dogs; Drug Therapy, Combination; Electrocar

1990
Reperfusion damage: free radicals mediate delayed membrane changes rather than early ventricular arrhythmias.
    Cardiovascular research, 1990, Volume: 24, Issue:2

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Catalase; Diltiazem; Dose-Response Relati

1990
Reperfusion injury in ischemic myocardium: effects of nifedipine and verapamil.
    The American journal of cardiovascular pathology, 1990, Volume: 3, Issue:1

    Topics: Animals; Blood Pressure; Calcium; Cell Nucleus; Glycogen; Microscopy, Electron; Mitochondria, Heart;

1990
[Diagnosis and prevention of myocardial reperfusion injury in experimental myocardial infarction].
    Kardiologiia, 1988, Volume: 28, Issue:12

    Topics: Animals; Butylated Hydroxytoluene; Calcium Channel Blockers; Cardiac Complexes, Premature; Constrict

1988
Treatment of reperfusion injury with intracoronary calcium channel antagonists and reduced coronary free calcium concentration in regionally ischemic, reperfused porcine hearts.
    Journal of the American College of Cardiology, 1989, Volume: 13, Issue:6

    Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Egtazic Acid; Female; Infusions, Intra-Arteri

1989
Verapamil preserves myocardial performance and energy metabolism in left ventricular hypertrophy following ischemia and reperfusion. Phosphorus 31 magnetic resonance spectroscopy study.
    Circulation, 1989, Volume: 80, Issue:6

    Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Energy Metabolism; Magnetic Res

1989
Effects of calcium antagonists and free radical scavengers on myocardial ischemia and reperfusion injury: evaluation by 31P-NMR spectroscopy.
    Japanese circulation journal, 1989, Volume: 53, Issue:9

    Topics: Adenosine; Adenosine Triphosphate; Animals; Catalase; Coronary Disease; Heart; In Vitro Techniques;

1989
[Reperfusion syndrome during thrombolytic therapy of myocardial infarct].
    Kardiologiia, 1989, Volume: 29, Issue:11

    Topics: Arrhythmias, Cardiac; Female; Fibrinolytic Agents; Hemodynamics; Humans; Male; Mexiletine; Middle Ag

1989
Resuscitation and preservation of agonally arrested hearts for transplantation: a study of 24 hour stored canine hearts.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Dogs; Epoprostenol; Heart; Heart Tr

1989
Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists.
    The Journal of surgical research, 1989, Volume: 47, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Consciousness; Coronary Disease; Diltiazem; Electrocardiography; Hear

1989
[Morphofunctional analysis of the efficacy of verapamil in experimental ischemia].
    Vrachebnoe delo, 1989, Issue:7

    Topics: Animals; Coronary Disease; Dogs; Drug Evaluation, Preclinical; Myocardial Contraction; Myocardial Re

1989
Effects of verapamil on ischaemia-induced impairment of ATP-dependent calcium extrusion in rat heart sarcolemma.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Radioisotopes; Coronary Disease; In Vitro Techniqu

1989
[Metabolism of the ischemic heart muscle and the effect of reperfusion and verapamil].
    Bratislavske lekarske listy, 1988, Volume: 89, Issue:11

    Topics: Animals; Coronary Disease; Heart; Humans; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myo

1988
[Experimental study on myocardial protection with verapamil cardioplegia].
    Zhonghua yi xue za zhi, 1988, Volume: 68, Issue:6

    Topics: Animals; Cardiac Output, Low; Cardioplegic Solutions; Cardiopulmonary Bypass; Dogs; Heart Arrest, In

1988
Evaluation of biochemical functions and ventricular performance in regional ischemic-reperfused myocardium by afterload reduction: differential effects of calcium blocking and non-calcium blocking vasodilators.
    International journal of cardiology, 1988, Volume: 21, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium; Heart; Mitochondria, Heart; Myocardial Contraction; Myocar

1988