verapamil has been researched along with Injury, Myocardial Reperfusion in 85 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Excerpt | Relevance | Reference |
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"The administration of verapamil during the reperfusion phase of acute myocardial infarction can reduce the extent and severity of microvessel damage and limit myocardial dysfunction." | 9.09 | Early administration of verapamil after thrombolysis in acute anterior myocardial infarction. Effect on left ventricular remodeling and clinical outcome. VAMI Study Group. Verapamil Acute Myocardial Infarction. ( Biasco, MG; Boni, L; Brigiani, MS; Iliceto, S; Marangelli, V; Memmola, C; Rizzon, P; Scrutinio, D, 2000) |
" In this study, we evaluated the ability of HO-4038, an N-hydroxypiperidine derivative of verapamil, on the modulation of myocardial tissue oxygenation (Po(2)), I/R injury, and key signaling molecules involved in cardioprotection in an in vivo rat model of acute myocardial infarction (MI)." | 7.75 | Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction. ( Bognar, B; Carnes, CA; Hideg, K; Kálai, T; Khan, M; Kuppusamy, P; Mohan, IK; Selvendiran, K; Sridhar, A; Wisel, S, 2009) |
"During the ischemic period, the low (clinically relevant) dose of mibefradil prevented the fall of the ventricular fibrillation threshold, without depressing the maximal rate of pressure development of the left ventricle (LVmax dP/dt)." | 7.70 | Effects of mibefradil, a novel calcium channel blocking agent with T-type activity, in acute experimental myocardial ischemia: maintenance of ventricular fibrillation threshold without inotropic compromise. ( Hofmann, D; McCarthy, J; Muller, CA; Opie, LH; Peisach, M; Pineda, CA, 1998) |
"This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion." | 7.70 | [Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999) |
"The authors evaluated the effects of verapamil (Ve) and magnesium sulfate (Mg) on the electrophysiologic changes induced in dogs during acute myocardial ischemia and following reperfusion." | 7.69 | Effects of verapamil and magnesium sulfate on electrophysiologic changes during acute myocardial ischemia and following reperfusion in dogs: comparative effects of administration by intravenous and coronary sinus retroperfusion routes. ( Bando, S; Yamamoto, K, 1996) |
"1." | 5.29 | Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs. ( Boulanger, CM; Kirchengast, M; Lee, JJ; Vanhoutte, PM, 1996) |
"Arrhythmias were associated with prolongation of transmural conduction time (CT) and abbreviation of endocardial effective refractory period." | 5.28 | Verapamil prevents slowing of transmural conduction and suppresses arrhythmias in an isolated guinea pig ventricular model of ischemia and reperfusion. ( Ferrier, GR; Li, GR, 1992) |
"Intracoronary verapamil restored myocardial perfusion in patients with angiographic no-reflow after PCI and lead to better functional recovery after acute myocardial infarction." | 5.12 | The effect of verapamil on the restoration of myocardial perfusion and functional recovery in patients with angiographic no-reflow after primary percutaneous coronary intervention. ( Baden, M; Fujitaka, K; Iwasaka, T; Nakamura, S; Sugiura, T; Tsuka, Y; Umemura, S; Yoshida, S, 2006) |
"The administration of verapamil during the reperfusion phase of acute myocardial infarction can reduce the extent and severity of microvessel damage and limit myocardial dysfunction." | 5.09 | Early administration of verapamil after thrombolysis in acute anterior myocardial infarction. Effect on left ventricular remodeling and clinical outcome. VAMI Study Group. Verapamil Acute Myocardial Infarction. ( Biasco, MG; Boni, L; Brigiani, MS; Iliceto, S; Marangelli, V; Memmola, C; Rizzon, P; Scrutinio, D, 2000) |
" In this study, we evaluated the ability of HO-4038, an N-hydroxypiperidine derivative of verapamil, on the modulation of myocardial tissue oxygenation (Po(2)), I/R injury, and key signaling molecules involved in cardioprotection in an in vivo rat model of acute myocardial infarction (MI)." | 3.75 | Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction. ( Bognar, B; Carnes, CA; Hideg, K; Kálai, T; Khan, M; Kuppusamy, P; Mohan, IK; Selvendiran, K; Sridhar, A; Wisel, S, 2009) |
" Mibefradil was compared with (+/-)-verapamil for effects on ischaemia- and reperfusion-induced ventricular fibrillation (VF), and the role of ischaemia-selective L-channel block was examined." | 3.70 | Inadequate ischaemia-selectivity limits the antiarrhythmic efficacy of mibefradil during regional ischaemia and reperfusion in the rat isolated perfused heart. ( Curtis, MJ; Farkas, A; Qureshi, A, 1999) |
"This study was designed to investigate whether two L-type calcium antagonists, verapamil and nicardipine reduce the myocardial necrosis (infarct size) following ischemia and reperfusion." | 3.70 | [Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model]. ( Furuya, M; Yoshida, K, 1999) |
"During the ischemic period, the low (clinically relevant) dose of mibefradil prevented the fall of the ventricular fibrillation threshold, without depressing the maximal rate of pressure development of the left ventricle (LVmax dP/dt)." | 3.70 | Effects of mibefradil, a novel calcium channel blocking agent with T-type activity, in acute experimental myocardial ischemia: maintenance of ventricular fibrillation threshold without inotropic compromise. ( Hofmann, D; McCarthy, J; Muller, CA; Opie, LH; Peisach, M; Pineda, CA, 1998) |
"Contrast-enhanced magnetic resonance (MR) imaging was used to detect and quantify the extent of myocardial injury after a brief coronary occlusion and reperfusion in response to verapamil treatment in a rat model of left ventricular hypertrophy (LVH)." | 3.69 | Verapamil reduces the size of reperfused ischemically injured myocardium in hypertrophied rat hearts as assessed by magnetic resonance imaging. ( Derugin, N; Higgins, CB; Lauerma, K; Saeed, M; Wendland, MF; Yu, KK, 1996) |
"The authors evaluated the effects of verapamil (Ve) and magnesium sulfate (Mg) on the electrophysiologic changes induced in dogs during acute myocardial ischemia and following reperfusion." | 3.69 | Effects of verapamil and magnesium sulfate on electrophysiologic changes during acute myocardial ischemia and following reperfusion in dogs: comparative effects of administration by intravenous and coronary sinus retroperfusion routes. ( Bando, S; Yamamoto, K, 1996) |
"Combination of chlorpromazine (CPZ) and verapamil (Ver) was found to decrease the incidence of ventricular arrhythmias and ventricular fibrillation induced by myocardial ischemia and reperfusion, lower serum creatine phosphokinase (CPK) and decrease the content of malondialdehyde (MDA) in heart tissue homogenate especially in mitochondria; and increase the phospholipid content and the phospholipid/cholesterol ratio; and decrease the myocardial "cell calcium" content in the reperfused area." | 3.68 | [Protective effects of combination of chlorpromazine and verapamil on ischemia-reperfusion induced injury in rat myocardium]. ( Deng, Y; Zhang, ZS, 1993) |
" The action of IHC-72 against aconitine induced arrhythmia was similar to that of Lid but stronger than that of Ver in anesthetized rats." | 3.68 | [Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil]. ( Ji, GJ; Liu, DQ; Sheng, BH; Zhao, DH, 1992) |
"The aim of the present study was to define the protective effects of verapamil and nifedipine on mechanical performance and energy and substrate metabolism of the postischemically reperfused myocardium in a chronic pressure overload cardiac hypertrophy model." | 3.68 | Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy. ( Buser, PT; Higgins, CB; Wagner, S; Wikman-Coffelt, J; Wu, S, 1991) |
"The effects of three calcium antagonists (diltiazem, verapamil, and nifedipine) on reperfusion-induced arrhythmias were compared in a conscious rat preparation with coronary artery occlusion and implanted electrocardiogram limb electrodes." | 3.67 | Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS; Mitani, A, 1989) |
"With verapamil there is a small tendency for a reduction in reinfarction, with nifedipine a clear worsening, and with diltiazem a reduction almost reaching statistical significance." | 2.38 | Protective effects of calcium antagonists against ischaemia and reperfusion damage. ( Ferrari, R; Visioli, O, 1991) |
"Verapamil or saline was given into the LAD artery either at the time the coronary artery was occluded (ie, during acute severe ischemia or during the reperfusion period)." | 1.34 | Calcium antagonist verapamil and reperfusion injury of the heart. ( Coetzee, A; Conradie, S, 2007) |
"To study the influence of acute renal failure in ischemic-reperfusion injury on the heart, we used isolated Langendorff's hearts of guinea pigs with gentamicin-induced acute renal failure." | 1.32 | Mibefradil is more effective than verapamil for restoring post-ischemic function of isolated hearts of guinea pigs with acute renal failure. ( Budihna, MV; Grasic Kuhar, C; Pleskovic, RZ, 2004) |
"Infarct, arrhythmia, heart rate and coronary artery flow were determined in hearts treated with vehicle, RST extract, Tet, Fan, or verapamil." | 1.31 | Cardiac effects of the extract and active components of radix stephaniae tetrandrae. II. Myocardial infarct, arrhythmias, coronary arterial flow and heart rate in the isolated perfused rat heart. ( Chen, CF; Pang, KT; Shan, J; Wang, GY; Wong, TM; Wu, S; Yu, XC, 2001) |
"Pretreatment with lidocaine (5 mg/kg), verapamil (0." | 1.30 | Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx. ( Dai, DZ; De Clerck, F; Lu, HR; Remeysen, P; Saels, A; Yang, P, 1999) |
"Diltiazem was the less effective drug on both left ventricular hemodynamics and coronary circulation." | 1.30 | Calcium-channel blockers preserve coronary endothelial reactivity after ischemia-reperfusion. ( Buluran, J; Cartier, R; Dagenais, F; Hollmann, C, 1997) |
"In nexopamil-treated pigs, this was paralleled by reduced release of creatine kinase (CK) into coronary venous blood." | 1.29 | Protection of reperfused ischemic pig myocardium by nexopamil, a new combined Ca2+ and serotonin antagonist. ( Braun, M; Hohlfeld, T; Schrör, K; Strobach, H, 1994) |
"Pretreatment with coenzyme Q10 given intraperitoneally improved aortic flow, cardiac output, stroke volume, coronary flow, and heart rate." | 1.29 | Improvement of cardiac function impaired by repeated ischemic arrests in isolated rat hearts. ( Ali, K; Fukaya, Y; Furukawa, Y; Morimoto, M, 1993) |
"Thus verapamil post-treatment can prevent reperfusion-induced myocardial injury but functional recovery may be delayed due to the drug's inherent direct myocardial depressant effect." | 1.29 | Effect of verapamil post-treatment in myocardial reperfusion injury. ( Gupta, YK; Manchanda, SC; Maulik, MG; Maulik, SK; Reddy, KS; Seth, SD, 1993) |
" R56865 was given before ischemia and with the onset of reperfusion, applying different dosing schedules, including an initial loading dose." | 1.29 | R56865 is antifibrillatory in reperfused ischemic guinea-pig hearts, even when given only during reperfusion. ( Guttmann, I; Mozes, A; Scheufler, E; Wilffert, B, 1995) |
"1." | 1.29 | Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs. ( Boulanger, CM; Kirchengast, M; Lee, JJ; Vanhoutte, PM, 1996) |
"Arrhythmias were associated with prolongation of transmural conduction time (CT) and abbreviation of endocardial effective refractory period." | 1.28 | Verapamil prevents slowing of transmural conduction and suppresses arrhythmias in an isolated guinea pig ventricular model of ischemia and reperfusion. ( Ferrier, GR; Li, GR, 1992) |
"Pretreatment with verapamil to reperfusion hearts decreased MPO activity to 4." | 1.28 | [Neutrophil infiltration in ischemic porcine myocardium and protective effect of verapamil]. ( Guo, ZG; Luo, WS; Tang, XL, 1990) |
"Verapamil cardioplegia was still better than Salvia miltiorrhiza Bunge." | 1.28 | [Experimental study on myocardial protection with verapamil and salvia miltiorrhiza Bunge cardioplegia]. ( Zhu, P, 1990) |
"DESIGN - Ventricular arrhythmias were studied in isolated rat hearts (n = 8-15 per experiment) subjected to regional ischaemia and treated with various free radical scavengers and spin trap agents." | 1.28 | Reperfusion damage: free radicals mediate delayed membrane changes rather than early ventricular arrhythmias. ( Coetzee, WA; Dennis, SC; Opie, LH; Owen, P; Saman, S, 1990) |
"4." | 1.28 | Effects of verapamil on ischaemia-induced impairment of ATP-dependent calcium extrusion in rat heart sarcolemma. ( Goddijn, MM; Haas, M; Punt, NC; van Amsterdam, FT; Zaagsma, J, 1989) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (14.12) | 18.7374 |
1990's | 50 (58.82) | 18.2507 |
2000's | 16 (18.82) | 29.6817 |
2010's | 7 (8.24) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Nihro, Y | 1 |
Sogawa, S | 1 |
Izumi, A | 1 |
Sasamori, A | 1 |
Sudo, T | 1 |
Miki, T | 1 |
Matsumoto, H | 1 |
Satoh, T | 1 |
Jiang, M | 1 |
Wang, Q | 1 |
Chen, J | 1 |
Wang, Y | 1 |
Fan, G | 1 |
Zhu, Y | 1 |
Sun, XQ | 1 |
Chen, S | 1 |
Wang, LF | 1 |
Chen, ZW | 1 |
Xiong, F | 1 |
Wang, H | 1 |
Feng, Y | 1 |
Li, Y | 1 |
Hua, X | 1 |
Pang, X | 1 |
Zhang, S | 1 |
Song, L | 1 |
Zhang, Y | 1 |
Gu, N | 1 |
Lishmanov, YB | 1 |
Maslov, LN | 1 |
Mukhomedzyanov, AV | 1 |
Mohan, IK | 2 |
Khan, M | 2 |
Wisel, S | 1 |
Selvendiran, K | 1 |
Sridhar, A | 2 |
Carnes, CA | 2 |
Bognar, B | 1 |
Kálai, T | 2 |
Hideg, K | 2 |
Kuppusamy, P | 2 |
Yu, W | 2 |
Wang, JJ | 2 |
Gan, WY | 1 |
Lin, GS | 2 |
Huang, CX | 2 |
Yi, XQ | 1 |
Li, T | 1 |
Wang, JR | 1 |
Wong, VK | 1 |
Luo, P | 1 |
Wong, IY | 1 |
Jiang, ZH | 1 |
Liu, L | 1 |
Zhou, H | 1 |
Wen, ZY | 1 |
Ouyang, JP | 1 |
Huang, H | 1 |
Ronson, RS | 1 |
Puskas, JD | 1 |
Thourani, VH | 1 |
Velez, DA | 1 |
Bufkin, BL | 1 |
Glass, J | 1 |
Guyton, RA | 1 |
Vinten-Johansen, J | 1 |
Shen, YL | 1 |
Chen, YY | 1 |
Wu, XD | 1 |
Bruce, IC | 1 |
Xia, Q | 1 |
Yu, XC | 2 |
Wu, S | 3 |
Chen, CF | 2 |
Pang, KT | 2 |
Wong, TM | 2 |
Grasic Kuhar, C | 2 |
Budihna, MV | 2 |
Pleskovic, RZ | 1 |
Reffelmann, T | 1 |
Kloner, RA | 1 |
Asemu, G | 1 |
Dhalla, NS | 1 |
Tappia, PS | 1 |
Alfayoumi, F | 1 |
Srinivasan, V | 1 |
Geller, M | 1 |
Gradman, A | 1 |
Umemura, S | 1 |
Nakamura, S | 1 |
Sugiura, T | 1 |
Tsuka, Y | 1 |
Fujitaka, K | 1 |
Yoshida, S | 2 |
Baden, M | 1 |
Iwasaka, T | 1 |
Kazanskaia, GM | 1 |
Volkov, AM | 1 |
D'iakonitsa, TM | 1 |
Zhdanov, GP | 1 |
Coetzee, A | 1 |
Conradie, S | 1 |
Mandal, R | 1 |
Kutala, VK | 1 |
Varadharaj, S | 1 |
Shan, D | 1 |
Marchase, RB | 1 |
Chatham, JC | 1 |
Hohlfeld, T | 1 |
Braun, M | 1 |
Strobach, H | 1 |
Schrör, K | 1 |
Richard, V | 1 |
Tron, C | 1 |
Blanc, T | 1 |
Thuillez, C | 1 |
Ken, N | 1 |
Katsuo, K | 1 |
Nagao, K | 1 |
Yanagida, S | 2 |
Ohsuzu, F | 2 |
Sakata, N | 2 |
Maie, S | 1 |
Akanuma, M | 1 |
Takayama, E | 1 |
Hayashi, K | 1 |
Aosaki, N | 1 |
Nakamura, H | 2 |
Ji, GJ | 2 |
Zhang, JZ | 1 |
Liu, DQ | 2 |
Zhao, DH | 2 |
Sheng, BH | 2 |
Deng, Y | 1 |
Zhang, ZS | 1 |
Zhou, J | 1 |
Xuan, B | 1 |
Li, DX | 1 |
Meng, HP | 1 |
Maddaford, TG | 1 |
Pierce, GN | 1 |
Curtis, MJ | 2 |
Garlick, PB | 1 |
Ridley, PD | 1 |
Ali, K | 1 |
Morimoto, M | 1 |
Fukaya, Y | 1 |
Furukawa, Y | 1 |
Maulik, SK | 1 |
Seth, SD | 1 |
Manchanda, SC | 1 |
Reddy, KS | 1 |
Gupta, YK | 1 |
Maulik, MG | 1 |
Scheufler, E | 1 |
Mozes, A | 1 |
Guttmann, I | 1 |
Wilffert, B | 1 |
Lauerma, K | 1 |
Saeed, M | 1 |
Wendland, MF | 1 |
Derugin, N | 2 |
Yu, KK | 1 |
Higgins, CB | 3 |
Chagas, AC | 2 |
Pileggi, F | 2 |
Lopes, EA | 1 |
Da-Luz, PL | 2 |
Yamamoto, K | 1 |
Bando, S | 1 |
Nearing, BD | 1 |
Hutter, JJ | 1 |
Verrier, RL | 1 |
Lee, JJ | 1 |
Boulanger, CM | 1 |
Kirchengast, M | 1 |
Vanhoutte, PM | 1 |
Dagenais, F | 1 |
Cartier, R | 1 |
Hollmann, C | 1 |
Buluran, J | 1 |
Muller, CA | 2 |
Opie, LH | 3 |
McCarthy, J | 2 |
Hofmann, D | 1 |
Pineda, CA | 2 |
Peisach, M | 1 |
Vrbjar, N | 1 |
Zöllner, S | 1 |
Haseloff, RF | 1 |
Pissarek, M | 1 |
Blasig, IE | 1 |
Kraljevic, V | 1 |
Lu, HR | 1 |
Yang, P | 1 |
Remeysen, P | 1 |
Saels, A | 1 |
Dai, DZ | 1 |
De Clerck, F | 1 |
Di Napoli, P | 1 |
Ranalli, G | 1 |
Di Crecchio, A | 1 |
Taccardi, AA | 1 |
Ausiello, A | 1 |
Di Muzio, M | 1 |
Barsotti, A | 1 |
Farkas, A | 1 |
Qureshi, A | 1 |
Furuya, M | 1 |
Yoshida, K | 1 |
Marangelli, V | 1 |
Memmola, C | 1 |
Brigiani, MS | 1 |
Boni, L | 1 |
Biasco, MG | 1 |
Scrutinio, D | 1 |
Iliceto, S | 1 |
Rizzon, P | 1 |
Wang, GY | 1 |
Shan, J | 1 |
Huddleston, CB | 1 |
Wareing, TH | 1 |
Boucek, RJ | 1 |
Hammon, JW | 1 |
Li, GR | 1 |
Ferrier, GR | 1 |
Soncul, H | 1 |
Gökgöz, L | 1 |
Karasu, C | 1 |
Ayrancioğlu, K | 1 |
Ersöz, A | 1 |
Altan, M | 1 |
Yener, A | 1 |
Yoshikawa, T | 1 |
Akaishi, M | 1 |
Ikeda, F | 1 |
Handa, S | 1 |
Nakamura, Y | 1 |
Vandeplassche, G | 1 |
Thoné, F | 1 |
Borgers, M | 1 |
Sullivan, AT | 1 |
Baker, DJ | 1 |
Drew, GM | 1 |
Ferrari, R | 1 |
Visioli, O | 1 |
Nayler, WG | 1 |
Buser, PT | 2 |
Wagner, S | 2 |
Wikman-Coffelt, J | 2 |
Chung, JK | 1 |
Lim, SM | 1 |
Lee, MC | 1 |
Koh, CS | 1 |
Lee, M | 1 |
Seo, JW | 1 |
Zhuang, XX | 1 |
Shvilkin, AV | 1 |
Afonskaia, NI | 1 |
Sadretdinov, SM | 1 |
Cherpachenko, NM | 1 |
Levitskiĭ, DO | 1 |
Ruda, MIa | 1 |
Yamamoto, F | 1 |
Yamamoto, H | 1 |
Ichikawa, H | 1 |
Takahashi, A | 1 |
Tanaka, K | 1 |
Kosakai, Y | 1 |
Yagihara, T | 1 |
Fujita, T | 1 |
Mjøs, OD | 1 |
Ichihara, K | 1 |
Fellenius, E | 1 |
Myrmel, T | 1 |
Neely, JR | 1 |
Huang, TF | 1 |
Huang, LL | 1 |
Luo, WS | 1 |
Guo, ZG | 1 |
Tang, XL | 1 |
Silveira, MC | 1 |
von Planta, M | 1 |
Weil, MH | 1 |
Gazmuri, RJ | 1 |
Ritz, MA | 1 |
Rackow, EC | 1 |
Zhu, P | 2 |
Rotevatn, S | 1 |
Greve, G | 1 |
Oksendal, AN | 1 |
Jynge, P | 1 |
Conorev, EA | 1 |
Rudnev, DV | 3 |
Conorev, LA | 1 |
Polumiskov, VY | 1 |
Golikov, AP | 2 |
Coetzee, WA | 1 |
Owen, P | 1 |
Dennis, SC | 1 |
Saman, S | 1 |
Mrak, RE | 1 |
Carry, MM | 1 |
Murphy, ML | 2 |
Peng, CF | 2 |
Straub, KD | 2 |
Pichigin, VV | 1 |
Konorev, EA | 1 |
Konorev, LA | 1 |
Polumiskov, VIu | 1 |
Klein, HH | 1 |
Pich, S | 1 |
Lindert, S | 1 |
Nebendahl, K | 1 |
Warneke, G | 1 |
Kreuzer, H | 1 |
Wu, ST | 1 |
Parmley, WW | 1 |
Shirakura, R | 1 |
Hirose, H | 1 |
Matsuda, H | 1 |
Nakano, S | 1 |
Nakata, S | 1 |
Ohtani, M | 1 |
Kawaguti, A | 1 |
Miyagawa, S | 1 |
Takami, H | 1 |
Naka, Y | 1 |
Kinoshita, K | 1 |
Mitani, A | 1 |
Hearse, DJ | 1 |
Braimbridge, MV | 1 |
Manning, AS | 1 |
Bratus', VV | 1 |
Sergienko, OV | 1 |
Bezus'ko, AG | 1 |
Shavaran, SS | 1 |
van Amsterdam, FT | 1 |
Goddijn, MM | 1 |
Haas, M | 1 |
Punt, NC | 1 |
Zaagsma, J | 1 |
Kucharská, J | 1 |
Gvozdjáková, A | 1 |
Gvozdják, J | 1 |
Odom, H | 1 |
Davis, JL | 1 |
4 reviews available for verapamil and Injury, Myocardial Reperfusion
Article | Year |
---|---|
The no-reflow phenomenon: epidemiology, pathophysiology, and therapeutic approach.
Topics: Adenosine; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Echocardiography; Hum | 2005 |
Myocardial protection in the occlusion/reperfusion dog model: the role of ischemic necrosis vs reperfusion injury.
Topics: Animals; Coronary Vessels; Deferoxamine; Disease Models, Animal; Dogs; Free Radicals; Iron; Myocardi | 1995 |
Protective effects of calcium antagonists against ischaemia and reperfusion damage.
Topics: Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Humans; Myocardial Reperfusion Injur | 1991 |
Basic mechanisms involved in the protection of the ischaemic myocardium. The role of calcium antagonists.
Topics: Calcium; Calcium Channel Blockers; Coronary Disease; Humans; Myocardial Reperfusion Injury; Myocardi | 1991 |
2 trials available for verapamil and Injury, Myocardial Reperfusion
Article | Year |
---|---|
The effect of verapamil on the restoration of myocardial perfusion and functional recovery in patients with angiographic no-reflow after primary percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Humans; Male; Myocardial Infarction; Myocardial Reperfusion In | 2006 |
Early administration of verapamil after thrombolysis in acute anterior myocardial infarction. Effect on left ventricular remodeling and clinical outcome. VAMI Study Group. Verapamil Acute Myocardial Infarction.
Topics: Calcium Channel Blockers; Double-Blind Method; Echocardiography; Female; Humans; Male; Middle Aged; | 2000 |
79 other studies available for verapamil and Injury, Myocardial Reperfusion
Article | Year |
---|---|
3-O-alkylascorbic acids as free radical quenchers. 3. Protective effect on coronary occlusion-reperfusion induced arrhythmias in anesthetized rats.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Ascorbic Acid; Blood Pressure; Fr | 1992 |
Comparative metabonomics of Wenxin Keli and Verapamil reveals differential roles of gluconeogenesis and fatty acid β-oxidation in myocardial injury protection.
Topics: Animals; Biomarkers; Cardiotonic Agents; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Acids; | 2017 |
Total flavones of Rhododendron simsii Planch flower protect isolated rat heart from ischaemia-reperfusion injury and its mechanism of UTR-RhoA-ROCK pathway inhibition.
Topics: Animals; Coronary Circulation; Creatine Kinase, MB Form; Dose-Response Relationship, Drug; Female; F | 2018 |
Cardioprotective activity of iron oxide nanoparticles.
Topics: Animals; Cardiotonic Agents; Cells, Cultured; Drug Evaluation, Preclinical; Female; Ferric Compounds | 2015 |
Role of β-Adrenoceptors and L-Type Ca(2+)-Channels in the Mechanism of Reperfusion-Induced Heart Injury.
Topics: Adrenergic beta-Antagonists; Animals; Calcium Channels, L-Type; Male; Myocardial Reperfusion Injury; | 2016 |
Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Blotting, Western; Calcium Channel Blockers; Calcium | 2009 |
[Effects of verapamil preconditioning on cardiac function in vitro and intracellular free Ca2+ and L-type calcium current in rat cardiomyocytes post ischemia-reperfusion injury].
Topics: Animals; Calcium; Calcium Channels, L-Type; Ischemic Preconditioning, Myocardial; Myocardial Reperfu | 2010 |
Total ginsenosides increase coronary perfusion flow in isolated rat hearts through activation of PI3K/Akt-eNOS signaling.
Topics: Animals; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells | 2010 |
[Influences and mechanism of verapamil on ischemia/reperfusion injury in cardiomyocytes of streptozotocin-induced diabetes mellitus rats].
Topics: Animals; Calcium; Calcium Channels, L-Type; Diabetes Mellitus, Experimental; Male; Myocardial Reperf | 2010 |
Controlled intermittent asystole cardiac therapy induced by pharmacologically potentiated vagus nerve stimulation in normal and hibernating myocardium.
Topics: Animals; Coronary Artery Bypass; Coronary Circulation; Coronary Stenosis; Creatine Kinase; Dogs; Dru | 2003 |
Activation of mitochondrial ATP-sensitive potassium channels delays ischemia-induced cellular uncoupling in rat heart.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Diazoxide; Hydroxy Acids; Ion Channel Gating; Ische | 2004 |
Antihypertensive and anti-arrhythmic effects of an extract of Radix Stephaniae Tetrandrae in the rat.
Topics: Alkaloids; Animals; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Benzylisoquinolines; Calcium | 2004 |
Mibefradil is more effective than verapamil for restoring post-ischemic function of isolated hearts of guinea pigs with acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Ca | 2004 |
Effects of adenosine and verapamil on anatomic no-reflow in a rabbit model of coronary artery occlusion and reperfusion.
Topics: Adenosine; Animals; Blood Pressure; Coronary Disease; Coronary Vasospasm; Disease Models, Animal; Ma | 2004 |
Inhibition of PLC improves postischemic recovery in isolated rat heart.
Topics: Animals; Calcium; Calcium Channel Blockers; Estrenes; Isoenzymes; Male; Myocardial Reperfusion Injur | 2004 |
[Endothelium of myocardium microvessel under conditions of hypothermia, ischemia, reperfusion and pharmaco-cold cardioplegia with calcium antagonist].
Topics: Calcium Channel Blockers; Cardioplegic Solutions; Coronary Vessels; Endothelium, Vascular; Heart Atr | 2005 |
Calcium antagonist verapamil and reperfusion injury of the heart.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Coronary Circulation; Myocardial Ischemia | 2007 |
N-hydroxy-pyrroline modification of verapamil exhibits antioxidant protection of the heart against ischemia/reperfusion-induced cardiac dysfunction without compromising its calcium antagonistic activity.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Free Radical Scavengers; In | 2007 |
Overexpression of TRPC3 increases apoptosis but not necrosis in response to ischemia-reperfusion in adult mouse cardiomyocytes.
Topics: Acrylates; Animals; Apoptosis; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium | 2008 |
Protection of reperfused ischemic pig myocardium by nexopamil, a new combined Ca2+ and serotonin antagonist.
Topics: Animals; Blood Platelets; Calcium Channel Blockers; Creatine Kinase; Diastole; Epoprostenol; Female; | 1994 |
Infarct size-limiting properties of Ro 40-5967, a novel nondihydropyridine calcium channel, in anesthetized rats: comparison with verapamil.
Topics: Anesthesia; Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Heart Rate; Hemodynam | 1995 |
[Myocardial reperfusion injury with coronary thrombolytic therapy--clinical and experimental studies].
Topics: Animals; Calcium; Dogs; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Ne | 1993 |
Protective effects of verapamil and adenosine treatment on high energy phosphate metabolism in ischemic and reperfused myocardium.
Topics: Adenosine; Animals; Energy Metabolism; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; M | 1994 |
Protective effects of 3,6-dimethylamino-dibenzopyriodonium edetate on global ischemia reperfused isolated rat hearts.
Topics: Animals; Anti-Arrhythmia Agents; Calcium; Coronary Circulation; Creatine Kinase; Edetic Acid; In Vit | 1993 |
[Protective effects of combination of chlorpromazine and verapamil on ischemia-reperfusion induced injury in rat myocardium].
Topics: Animals; Chlorpromazine; Drug Therapy, Combination; Female; Male; Mitochondria, Heart; Myocardial Re | 1993 |
Effects of tetrahydroberberine on ischemic and reperfused myocardium in rats.
Topics: Animals; Anti-Arrhythmia Agents; Berberine; Berberine Alkaloids; In Vitro Techniques; Male; Malondia | 1993 |
Effect of amiloride and selected analogues on postischemic recovery of cardiac contractile function.
Topics: Amiloride; Animals; Carrier Proteins; Coronary Disease; Creatine Kinase; Male; Myocardial Contractio | 1993 |
Anion manipulation, a novel antiarrhythmic approach: mechanism of action.
Topics: Animals; Anions; Blood Pressure; Bromides; Chlorides; Coronary Circulation; Cyclic AMP; Cyclic GMP; | 1993 |
Improvement of cardiac function impaired by repeated ischemic arrests in isolated rat hearts.
Topics: Animals; Aorta; Bicarbonates; Calcium Chloride; Cardiac Output; Cardioplegic Solutions; Coenzymes; C | 1993 |
Effect of verapamil post-treatment in myocardial reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Creatine Kinase; Depression, Chemical; Dogs; Myocardial Contraction | 1993 |
R56865 is antifibrillatory in reperfused ischemic guinea-pig hearts, even when given only during reperfusion.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzothiazoles; Calcium; Calcium Channel Block | 1995 |
Verapamil reduces the size of reperfused ischemically injured myocardium in hypertrophied rat hearts as assessed by magnetic resonance imaging.
Topics: Animals; Aorta, Abdominal; Calcium Channel Blockers; Coloring Agents; Contrast Media; Disease Models | 1996 |
Effects of verapamil and magnesium sulfate on electrophysiologic changes during acute myocardial ischemia and following reperfusion in dogs: comparative effects of administration by intravenous and coronary sinus retroperfusion routes.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Vessels; Dogs; Electrophysiology | 1996 |
Potent antifibrillatory effect of combined blockade of calcium channels and 5-HT2 receptors with nexopamil during myocardial ischemia and reperfusion in dogs: comparison to diltiazem.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; El | 1996 |
Trandolapril plus verapamil inhibits the coronary vasospasm induced by hypoxia following ischemia-reperfusion injury in dogs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Coronary Vasospasm; Dog | 1996 |
Calcium-channel blockers preserve coronary endothelial reactivity after ischemia-reperfusion.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Diltiazem; Dose-Response | 1997 |
Effects of mibefradil, a novel calcium channel blocking agent with T-type activity, in acute experimental myocardial ischemia: maintenance of ventricular fibrillation threshold without inotropic compromise.
Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electrocardiogr | 1998 |
PBN spin trapping of free radicals in the reperfusion-injured heart. Limitations for pharmacological investigations.
Topics: Animals; Antioxidants; Arrhythmias, Cardiac; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; | 1998 |
Combination of a calcium antagonist, verapamil, with an angiotensin converting enzyme inhibitor, trandolapril, in experimental myocardial ischemia and reperfusion: antiarrhythmic and hemodynamic effects of chronic oral pretreatment.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Cal | 1998 |
Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx.
Topics: Amiloride; Anesthesia; Animals; Arrhythmias, Cardiac; Benzothiazoles; Blood Pressure; Calcium; Calci | 1999 |
[The effects of verapamil on the postischemic changes in the coronary microcirculation: the role of nitric oxide].
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; In Vitro Techniques; Male; Microcirculation | 1999 |
Inadequate ischaemia-selectivity limits the antiarrhythmic efficacy of mibefradil during regional ischaemia and reperfusion in the rat isolated perfused heart.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channel | 1999 |
[Comparison of effects of verapamil and those of nicardipine on myocardial ischemia and reperfusion injury: a study in an in situ rabbit model].
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disease Models, Animal; Myocardial Ischem | 1999 |
Effects of mibefradil and verapamil on ischemic-reperfusion in the hearts of guinea pigs with acute renal failure.
Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Coronary Circulation; Female; Guinea Pigs; L | 2000 |
Cardiac effects of the extract and active components of radix stephaniae tetrandrae. II. Myocardial infarct, arrhythmias, coronary arterial flow and heart rate in the isolated perfused rat heart.
Topics: Alkaloids; Animals; Arrhythmias, Cardiac; Benzylisoquinolines; Calcium Channel Blockers; Coronary Ci | 2001 |
[Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil].
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Edetic Acid; Female; Guinea Pigs; | 1992 |
Response of the hypertrophied left ventricle to global ischemia. Comparison of hyperkalemic cardioplegic solution with and without verapamil.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Cardioplegic Solutions; Cardiopulmonary Bypass; Dogs; | 1992 |
Verapamil prevents slowing of transmural conduction and suppresses arrhythmias in an isolated guinea pig ventricular model of ischemia and reperfusion.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Electrocardiography; Guinea Pigs; Heart Conduction | 1992 |
Comparison of potassium and adenosine cardioplegia with or without verapamil in the isolated guinea pig heart.
Topics: Adenosine; Animals; Cardioplegic Solutions; Guinea Pigs; Heart Arrest, Induced; Heart Rate; Male; My | 1992 |
Postischaemic hypercontraction is enhanced in ischaemically injured canine myocardium.
Topics: Animals; Calcium; Coronary Disease; Disease Models, Animal; Dogs; Myocardial Contraction; Myocardial | 1992 |
Protective effects of R 56 865 against ischemic damage in the isolated rabbit heart.
Topics: Animals; Benzothiazoles; Calcium; Calcium Channels; Cell Death; Coronary Disease; Female; Hemodynami | 1991 |
Effect of calcium channel blocking agents on infarct size after ischaemia-reperfusion in anaesthetised pigs: relationship between cardioprotection and cardiodepression.
Topics: Animals; Aspirin; Coronary Vessels; Depression, Chemical; Heart; Hemodynamics; Injections, Intra-Art | 1991 |
Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Cardiomegaly; Energy Metabolism; Hyperten | 1991 |
Evaluation of the protective effect of verapamil on reperfusion injury by 111In anticardiac myosin antibody in canine myocardial infarction.
Topics: Animals; Dogs; Evaluation Studies as Topic; Indium Radioisotopes; Myocardial Infarction; Myocardial | 1991 |
[Protective effect of Angelica injection on arrhythmia during myocardial ischemia reperfusion in rat].
Topics: Animals; Arrhythmias, Cardiac; Drugs, Chinese Herbal; Female; Injections, Intraperitoneal; Male; Myo | 1991 |
[Effects of verapamil and nitroglycerin on experimental occlusion- reperfusion-induced myocardial infarction in rabbits].
Topics: Animals; Coronary Vessels; Disease Models, Animal; Drug Evaluation, Preclinical; Ligation; Male; Myo | 1991 |
The effects of several pharmacologic agents upon postischemic recovery.
Topics: Animals; Calcium; Cardioplegic Solutions; Coenzymes; Creatine Kinase; Gabexate; Guanidines; In Vitro | 1991 |
Fatty acids suppress recovery of heart function after hypothermic perfusion.
Topics: Acyl Coenzyme A; Adenosine Triphosphate; Animals; Calcium; Carnitine; Coronary Circulation; Fatty Ac | 1991 |
Drug effects on myocardial ischemia- and reperfusion-induced arrhythmias in anesthetized rats.
Topics: Animals; Arrhythmias, Cardiac; Aspirin; Coronary Disease; Male; Mannitol; Myocardial Reperfusion Inj | 1991 |
[Neutrophil infiltration in ischemic porcine myocardium and protective effect of verapamil].
Topics: Animals; Female; Leukocyte Count; Male; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Pero | 1990 |
Myocardial protection by verapamil and reperfusion following coronary occlusion.
Topics: Animals; Blood Pressure; Dogs; Heart Rate; Myocardial Infarction; Myocardial Reperfusion; Myocardial | 1990 |
Calcium-entry blockers during porcine cardiopulmonary resuscitation.
Topics: Animals; Blood Pressure; Diltiazem; Disease Models, Animal; Heart Arrest; Hydrogen-Ion Concentration | 1990 |
[Experimental study on myocardial protection with verapamil and salvia miltiorrhiza Bunge cardioplegia].
Topics: Animals; Calcium Channels; Cardioplegic Solutions; Cardiopulmonary Bypass; Dogs; Drug Combinations; | 1990 |
Tissue protection by verapamil in the calcium paradox.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Chloride; Creatine Kinase; | 1990 |
Pharmacologic modifications of reperfusion arrhythmias in the dog in vivo: possible relation to limitation of the extent of infarction.
Topics: Animals; Arrhythmias, Cardiac; Butylated Hydroxytoluene; Dogs; Drug Therapy, Combination; Electrocar | 1990 |
Reperfusion damage: free radicals mediate delayed membrane changes rather than early ventricular arrhythmias.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Catalase; Diltiazem; Dose-Response Relati | 1990 |
Reperfusion injury in ischemic myocardium: effects of nifedipine and verapamil.
Topics: Animals; Blood Pressure; Calcium; Cell Nucleus; Glycogen; Microscopy, Electron; Mitochondria, Heart; | 1990 |
[Diagnosis and prevention of myocardial reperfusion injury in experimental myocardial infarction].
Topics: Animals; Butylated Hydroxytoluene; Calcium Channel Blockers; Cardiac Complexes, Premature; Constrict | 1988 |
Treatment of reperfusion injury with intracoronary calcium channel antagonists and reduced coronary free calcium concentration in regionally ischemic, reperfused porcine hearts.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Egtazic Acid; Female; Infusions, Intra-Arteri | 1989 |
Verapamil preserves myocardial performance and energy metabolism in left ventricular hypertrophy following ischemia and reperfusion. Phosphorus 31 magnetic resonance spectroscopy study.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Energy Metabolism; Magnetic Res | 1989 |
Effects of calcium antagonists and free radical scavengers on myocardial ischemia and reperfusion injury: evaluation by 31P-NMR spectroscopy.
Topics: Adenosine; Adenosine Triphosphate; Animals; Catalase; Coronary Disease; Heart; In Vitro Techniques; | 1989 |
[Reperfusion syndrome during thrombolytic therapy of myocardial infarct].
Topics: Arrhythmias, Cardiac; Female; Fibrinolytic Agents; Hemodynamics; Humans; Male; Mexiletine; Middle Ag | 1989 |
Resuscitation and preservation of agonally arrested hearts for transplantation: a study of 24 hour stored canine hearts.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Dogs; Epoprostenol; Heart; Heart Tr | 1989 |
Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists.
Topics: Animals; Arrhythmias, Cardiac; Consciousness; Coronary Disease; Diltiazem; Electrocardiography; Hear | 1989 |
[Morphofunctional analysis of the efficacy of verapamil in experimental ischemia].
Topics: Animals; Coronary Disease; Dogs; Drug Evaluation, Preclinical; Myocardial Contraction; Myocardial Re | 1989 |
Effects of verapamil on ischaemia-induced impairment of ATP-dependent calcium extrusion in rat heart sarcolemma.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Radioisotopes; Coronary Disease; In Vitro Techniqu | 1989 |
[Metabolism of the ischemic heart muscle and the effect of reperfusion and verapamil].
Topics: Animals; Coronary Disease; Heart; Humans; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myo | 1988 |
[Experimental study on myocardial protection with verapamil cardioplegia].
Topics: Animals; Cardiac Output, Low; Cardioplegic Solutions; Cardiopulmonary Bypass; Dogs; Heart Arrest, In | 1988 |
Evaluation of biochemical functions and ventricular performance in regional ischemic-reperfused myocardium by afterload reduction: differential effects of calcium blocking and non-calcium blocking vasodilators.
Topics: Adenosine Triphosphate; Animals; Calcium; Heart; Mitochondria, Heart; Myocardial Contraction; Myocar | 1988 |