verapamil has been researched along with Inflammation in 37 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hesperetin (HSP) is a natural flavonoid that offers useful curative effects for cardiovascular diseases, but its effect on myocardial ischemia and its precise mechanism remains unclear." | 8.02 | Hesperetin modulates the Sirt1/Nrf2 signaling pathway in counteracting myocardial ischemia through suppression of oxidative stress, inflammation, and apoptosis. ( Chu, L; Han, X; Jing, X; Li, J; Liu, M; Liu, P; Xue, Y; Zhang, M; Zhang, Y, 2021) |
| "The objective of this study was to investigate the exact therapeutic effects of Verapamil on lipopolysaccharide (LPS)-induced acute lung injury (ALI) and the molecular mechanism involved, through using LPS-induced animal models as well as LPS-stimulated mouse primary peritoneal macrophages models." | 7.91 | The therapeutic effect of verapamil in lipopolysaccharide-induced acute lung injury. ( Han, L; Li, S; Liu, Y; Song, Z; Yuan, L; Zhang, C, 2019) |
| "Verapamil is a useful drug with therapeutic targeting on GCH and a potential way to limit mucous production and improve bronchial inflammation." | 7.78 | Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals. ( Ghafarzadegan, K; Hadi, R; Khakzad, MR; Meshkat, M; Mirsadraee, M; Mohammadpour, A; Saghari, M, 2012) |
| "Colchicine is an alkaloid drug commonly used in familial Mediterranean fever (FMF), gout, Behcet's syndrome, psoriasis and Sweet's syndrome." | 7.70 | Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases? ( Ben-Chetrit, E; Levy, M, 1998) |
| "The aim of this study was to investigate whether the blockade of L-type Ca2+ channels with verapamil suppresses giant migrating contractions (GMCs) and therefore diarrhea during small intestinal inflammation." | 7.69 | Ca2+ channel blockade by verapamil inhibits GMCs and diarrhea during small intestinal inflammation. ( Casper, MA; Lee, CW; Sarna, SK; Singaram, C, 1997) |
| "The objective of this study was to evaluate the suitability of the early phase of adjuvant arthritis (pre-AA) as a model of inflammation for pharmacokinetic studies." | 5.33 | Effect of early phase adjuvant arthritis on hepatic P450 enzymes and pharmacokinetics of verapamil: an alternative approach to the use of an animal model of inflammation for pharmacokinetic studies. ( Jamali, F; Ling, S, 2005) |
| "Hesperetin (HSP) is a natural flavonoid that offers useful curative effects for cardiovascular diseases, but its effect on myocardial ischemia and its precise mechanism remains unclear." | 4.02 | Hesperetin modulates the Sirt1/Nrf2 signaling pathway in counteracting myocardial ischemia through suppression of oxidative stress, inflammation, and apoptosis. ( Chu, L; Han, X; Jing, X; Li, J; Liu, M; Liu, P; Xue, Y; Zhang, M; Zhang, Y, 2021) |
| "The objective of this study was to investigate the exact therapeutic effects of Verapamil on lipopolysaccharide (LPS)-induced acute lung injury (ALI) and the molecular mechanism involved, through using LPS-induced animal models as well as LPS-stimulated mouse primary peritoneal macrophages models." | 3.91 | The therapeutic effect of verapamil in lipopolysaccharide-induced acute lung injury. ( Han, L; Li, S; Liu, Y; Song, Z; Yuan, L; Zhang, C, 2019) |
| "Verapamil is a useful drug with therapeutic targeting on GCH and a potential way to limit mucous production and improve bronchial inflammation." | 3.78 | Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals. ( Ghafarzadegan, K; Hadi, R; Khakzad, MR; Meshkat, M; Mirsadraee, M; Mohammadpour, A; Saghari, M, 2012) |
| "Inflammation elevates plasma verapamil concentrations but diminishes pharmacological response." | 3.74 | Effects of angiotensin II blockade on inflammation-induced alterations of pharmacokinetics and pharmacodynamics of calcium channel blockers. ( Dagenais, NJ; Dryden, WF; Hanafy, S; Jamali, F, 2008) |
| "Colchicine is an alkaloid drug commonly used in familial Mediterranean fever (FMF), gout, Behcet's syndrome, psoriasis and Sweet's syndrome." | 3.70 | Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases? ( Ben-Chetrit, E; Levy, M, 1998) |
| "The influence of endotoxin-induced inflammation on the enantioselective pharmacokinetics of propranolol, oxprenolol, and verapamil, which bind to alpha 1-acid glycoprotein, was studied in the rat." | 3.69 | Influence of endotoxin on the stereoselective pharmacokinetics of oxprenolol, propranolol, and verapamil in the rat. ( Belpaire, FM; Bogaert, MG; Laethem, ME; Rosseel, MT; Wijnant, P, 1994) |
| "The aim of this study was to investigate whether the blockade of L-type Ca2+ channels with verapamil suppresses giant migrating contractions (GMCs) and therefore diarrhea during small intestinal inflammation." | 3.69 | Ca2+ channel blockade by verapamil inhibits GMCs and diarrhea during small intestinal inflammation. ( Casper, MA; Lee, CW; Sarna, SK; Singaram, C, 1997) |
| "Fibrinogen and WBC were independent predictors of CV death or non-fatal MI as well as disease progression leading to revascularization in patients with stable angina pectoris." | 2.69 | Inflammatory and hemostatic markers in relation to cardiovascular prognosis in patients with stable angina pectoris. Results from the APSIS study. The Angina Prognosis Study in Stockholm. ( Björkander, I; Forslund, L; Håkan Wallén, N; Held, C; Hjemdahl, P; Rehnqvist, N; Wiman, B, 2000) |
| "Treatment of verapamil attenuated inflammation as well as joint destruction in arthritis models." | 1.43 | Chronic Calcium Channel Inhibitor Verapamil Antagonizes TNF-α-Mediated Inflammatory Reaction and Protects Against Inflammatory Arthritis in Mice. ( Li, W; Li, Z; Liu, Y; Meng, Q; Pan, J; Wang, W; Wang, X; Yan, P; Zhai, Y; Zhang, H; Zhang, P; Zhang, Z; Zhao, Y, 2016) |
| "Treatment with verapamil blocked these effects." | 1.37 | Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity. ( Abdelsaid, MA; Al-Gayyar, MM; El-Remessy, AB; Matragoon, S; Pillai, BA, 2011) |
| "P-glycoprotein is an efflux pump belonging to the ATP-binding cassette super-family that influences the bioavailability and disposition of many drugs." | 1.36 | Tumor necrosis factor alpha increases P-glycoprotein expression in a BME-UV in vitro model of mammary epithelial cells. ( Al-Bataineh, MM; Gehring, R; Schultz, BD; van der Merwe, D, 2010) |
| "The objective of this study was to evaluate the suitability of the early phase of adjuvant arthritis (pre-AA) as a model of inflammation for pharmacokinetic studies." | 1.33 | Effect of early phase adjuvant arthritis on hepatic P450 enzymes and pharmacokinetics of verapamil: an alternative approach to the use of an animal model of inflammation for pharmacokinetic studies. ( Jamali, F; Ling, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.70) | 18.7374 |
| 1990's | 10 (27.03) | 18.2507 |
| 2000's | 5 (13.51) | 29.6817 |
| 2010's | 17 (45.95) | 24.3611 |
| 2020's | 4 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Nozal, V | 1 |
| Martínez-González, L | 1 |
| Gomez-Almeria, M | 1 |
| Gonzalo-Consuegra, C | 1 |
| Santana, P | 1 |
| Chaikuad, A | 1 |
| Pérez-Cuevas, E | 1 |
| Knapp, S | 1 |
| Lietha, D | 1 |
| Ramírez, D | 1 |
| Petralla, S | 1 |
| Monti, B | 1 |
| Gil, C | 1 |
| Martín-Requero, A | 1 |
| Palomo, V | 1 |
| de Lago, E | 1 |
| Martinez, A | 1 |
| Szychowski, KA | 1 |
| Skóra, B | 1 |
| Tabęcka-Łonczyńska, A | 1 |
| Song, Z | 1 |
| Li, S | 1 |
| Zhang, C | 1 |
| Yuan, L | 1 |
| Han, L | 1 |
| Liu, Y | 3 |
| Jiang, J | 1 |
| Shi, Y | 1 |
| Cao, J | 1 |
| Lu, Y | 1 |
| Sun, G | 1 |
| Yang, J | 1 |
| Liu, P | 1 |
| Li, J | 1 |
| Liu, M | 1 |
| Zhang, M | 1 |
| Xue, Y | 1 |
| Zhang, Y | 1 |
| Han, X | 1 |
| Jing, X | 1 |
| Chu, L | 1 |
| Ding, S | 1 |
| Zhang, J | 1 |
| Yin, S | 1 |
| Lu, J | 1 |
| Hu, M | 1 |
| Du, J | 1 |
| Huang, J | 1 |
| Shen, B | 1 |
| Zanotti-Fregonara, P | 1 |
| Veronese, M | 1 |
| Pascual, B | 1 |
| Rostomily, RC | 1 |
| Turkheimer, F | 1 |
| Masdeu, JC | 1 |
| Xu, L | 1 |
| Lin, X | 1 |
| Guan, M | 1 |
| Zeng, Y | 1 |
| Khan, H | 2 |
| Saeed, M | 2 |
| Mehmood, MH | 2 |
| Rehman, NU | 2 |
| Muhammad, N | 2 |
| Haq, IU | 2 |
| Ashraf, N | 1 |
| El-Tahir, KE | 1 |
| Gilani, AH | 2 |
| Ribeiro-Filho, J | 1 |
| Calheiros, AS | 1 |
| Vieira-de-Abreu, A | 1 |
| de Carvalho, KI | 1 |
| da Silva Mendes, D | 1 |
| Melo, CB | 1 |
| Martins, MA | 1 |
| da Silva Dias, C | 1 |
| Piuvezam, MR | 1 |
| Bozza, PT | 1 |
| Paulis, G | 3 |
| Cavallini, G | 2 |
| Giorgio, GD | 1 |
| Quattrocchi, S | 1 |
| Brancato, T | 3 |
| Alvaro, R | 2 |
| Demeure, F | 1 |
| Hanin, FX | 1 |
| Bol, A | 1 |
| Vincent, MF | 1 |
| Pouleur, AC | 1 |
| Gerber, B | 1 |
| Pasquet, A | 1 |
| Jamar, F | 1 |
| Vanoverschelde, JL | 1 |
| Vancraeynest, D | 1 |
| Xiong, YJ | 1 |
| Chu, HW | 1 |
| Lin, Y | 1 |
| Han, F | 1 |
| Li, YC | 1 |
| Wang, AG | 1 |
| Wang, FJ | 1 |
| Chen, DP | 1 |
| Wang, JY | 1 |
| Wang, W | 1 |
| Li, Z | 1 |
| Meng, Q | 1 |
| Zhang, P | 1 |
| Yan, P | 1 |
| Zhang, Z | 1 |
| Zhang, H | 1 |
| Pan, J | 1 |
| Zhai, Y | 1 |
| Wang, X | 1 |
| Li, W | 1 |
| Zhao, Y | 1 |
| Al-Bataineh, MM | 1 |
| van der Merwe, D | 1 |
| Schultz, BD | 1 |
| Gehring, R | 1 |
| Al-Gayyar, MM | 1 |
| Abdelsaid, MA | 1 |
| Matragoon, S | 1 |
| Pillai, BA | 1 |
| El-Remessy, AB | 1 |
| Khakzad, MR | 1 |
| Mirsadraee, M | 1 |
| Mohammadpour, A | 1 |
| Ghafarzadegan, K | 1 |
| Hadi, R | 1 |
| Saghari, M | 1 |
| Meshkat, M | 1 |
| Erickson, MA | 1 |
| Hansen, K | 1 |
| Banks, WA | 1 |
| Abbas, M | 1 |
| Ling, S | 1 |
| Jamali, F | 2 |
| Törnqvist, H | 1 |
| Mills, NL | 1 |
| Gonzalez, M | 1 |
| Miller, MR | 1 |
| Robinson, SD | 1 |
| Megson, IL | 1 |
| Macnee, W | 1 |
| Donaldson, K | 1 |
| Söderberg, S | 1 |
| Newby, DE | 1 |
| Sandström, T | 1 |
| Blomberg, A | 1 |
| Hanafy, S | 1 |
| Dagenais, NJ | 1 |
| Dryden, WF | 1 |
| Nagahisa, A | 1 |
| Asai, R | 1 |
| Kanai, Y | 1 |
| Murase, A | 1 |
| Tsuchiya-Nakagaki, M | 1 |
| Nakagaki, T | 1 |
| Shieh, TC | 1 |
| Taniguchi, K | 1 |
| Laethem, ME | 1 |
| Belpaire, FM | 1 |
| Wijnant, P | 1 |
| Rosseel, MT | 1 |
| Bogaert, MG | 1 |
| Tjandrawinata, RR | 1 |
| Hawel, L | 1 |
| Byus, CV | 1 |
| Viswanadham, CK | 1 |
| Patil, PA | 1 |
| Lee, CW | 1 |
| Sarna, SK | 1 |
| Singaram, C | 1 |
| Casper, MA | 1 |
| Ben-Chetrit, E | 1 |
| Levy, M | 1 |
| Held, C | 1 |
| Hjemdahl, P | 1 |
| Håkan Wallén, N | 1 |
| Björkander, I | 1 |
| Forslund, L | 1 |
| Wiman, B | 1 |
| Rehnqvist, N | 1 |
| Hingorani, AD | 1 |
| Cross, J | 1 |
| Kharbanda, RK | 1 |
| Mullen, MJ | 1 |
| Bhagat, K | 1 |
| Taylor, M | 1 |
| Donald, AE | 1 |
| Palacios, M | 1 |
| Griffin, GE | 1 |
| Deanfield, JE | 1 |
| MacAllister, RJ | 1 |
| Vallance, P | 1 |
| Shi, Z | 1 |
| Luo, W | 1 |
| Xiu, Q | 1 |
| Ye, Y | 1 |
| Yan, Z | 1 |
| Zhu, Q | 1 |
| Gürdal, H | 1 |
| Sara, Y | 1 |
| Tulunay, FC | 1 |
| Chen, WR | 1 |
| Yang, YX | 1 |
| Zheng, HQ | 1 |
| A, SY | 1 |
| Liu, F | 1 |
| Zhu, BQ | 1 |
| Parmley, WW | 1 |
| Srivastava, VK | 1 |
| Saxena, KK | 1 |
| Gupta, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase Ib/II Clinical Trial of Topical Verapamil Hydrochloride for Chronic Rhinosinusitis With Nasal Polyps[NCT03102190] | Phase 1 | 6 participants (Actual) | Interventional | 2017-06-05 | Terminated (stopped due to Phase II funding not available) | ||
| Randomized Double Blind Placebo Controlled Trial of Verapamil in Chronic Rhinosinusitis[NCT02454608] | 29 participants (Actual) | Interventional | 2015-05-31 | Terminated (stopped due to Evidence that the dose is insufficient.) | |||
| The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin[NCT00745693] | 15 participants (Actual) | Interventional | 2008-03-31 | Completed | |||
| The Effects of Diesel Exhaust Inhalation On Exercise Capacity In Patients With Stable Angina Pectoris[NCT00737958] | 19 participants (Actual) | Observational | 2008-08-31 | Completed | |||
| Effects of Ambient Air Pollution Exposure in Patients With Stable Angina Pectoris During Normal Daily Activities[NCT00738491] | 1 participants (Actual) | Observational | 2008-08-31 | Terminated (stopped due to Study performed in alternative location (Beijing China)) | |||
| A Double-blind, Randomised, Placebo-controlled Parallel Study to Investigate the Effect of Dietary Nitrate on a Model of Vascular Dysfunction in Healthy Volunteers[NCT02715635] | Phase 1 | 78 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| Investigation of the Influence of Gender on Cardiovascular Function and Inflammation[NCT01582321] | Early Phase 1 | 56 participants (Anticipated) | Interventional | 2012-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Dose Limiting Toxicity will be defined as a development of 2nd or 3rd degree heart block as measured by an EKG. (Phase Ib primary outcome) (NCT03102190)
Timeframe: 1-8 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Phase Ib | 0 |
(NCT02454608)
Timeframe: Mean change between baseline and week 8 measurements
| Intervention | mmHg (Mean) |
|---|---|
| Treatment | -0.6 |
| Control | 1 |
(NCT02454608)
Timeframe: Mean change between baseline and week 8 measurements.
| Intervention | beats per minute (Mean) |
|---|---|
| Treatment | -1.4 |
| Control | 4 |
Minimum Score: 0 Maximum Score: 12 Higher value represents worse outcome. (NCT02454608)
Timeframe: baseline to week 8
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Treatment | -1.3 |
| Control | -0.25 |
Minimum Score: 0 Maximum Score: 24 Higher value represents worse outcome. (NCT02454608)
Timeframe: Week 8
| Intervention | units on a scale (Mean) |
|---|---|
| Treatment | 12.5 |
| Control | 17.7 |
Minimum Score: 0 Maximum Score: 100 A higher score indicates a worse outcome. (NCT02454608)
Timeframe: baseline to week 8
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Treatment | -44.03 |
| Control | -6.07 |
Minimum Score: 0 Maximum Score: 110 A higher score indicates a worse outcome (NCT02454608)
Timeframe: baseline to week 8
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Treatment | -27.3 |
| Control | 0.4 |
(NCT02454608)
Timeframe: Mean change between baseline and week 8 measurements
| Intervention | mmHg (Mean) |
|---|---|
| Treatment | -4.5 |
| Control | -6.6 |
Minimum Score: 0 Maximum Score: 100 A higher score indicates a worse outcome. (NCT02454608)
Timeframe: baseline to week 56
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| Medicine Completers, baseline | Medicine Completers, week 56 | Surgical Completers, baseline | Surgical Completers, week 12 | |
| Open Label | 64.3 | 35.0 | 90.0 | 16.7 |
Minimum Score: 0 Maximum Score: 110 A higher score indicates a worse outcome (NCT02454608)
Timeframe: baseline to week 56
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| Medicine Completers, baseline | Medicine Completers, week 56 | Surgical Completers, baseline | Surgical Completers, week 12 | |
| Open Label | 31.8 | 24.14 | 72.00 | 8.00 |
2 reviews available for verapamil and Inflammation
| Article | Year |
|---|---|
Inflammatory mechanisms and oxidative stress in Peyronie's disease: therapeutic "rationale" and related emerging treatment strategies.
Topics: Animals; Colchicine; Humans; Inflammation; Male; Oxidative Stress; Penile Induration; Penis; Reactiv | 2012 |
Modification of experimental and clinical atherosclerosis by dietary fish oil.
Topics: Animals; Anticoagulants; Arteriosclerosis; Blood Pressure; Dietary Fats, Unsaturated; Epoprostenol; | 1990 |
6 trials available for verapamil and Inflammation
| Article | Year |
|---|---|
Long-term multimodal therapy (verapamil associated with propolis, blueberry, vitamin E and local diclofenac) on patients with Peyronie's disease (chronic inflammation of the tunica albuginea). Results of a controlled study.
Topics: Adult; Aged; Aged, 80 and over; Blueberry Plants; Case-Control Studies; Diclofenac; Humans; Inflamma | 2013 |
A randomized trial on the optimization of 18F-FDG myocardial uptake suppression: implications for vulnerable coronary plaque imaging.
Topics: Adult; Coronary Vessels; Diet; Fatty Acids, Nonesterified; Female; Fluorodeoxyglucose F18; Healthy V | 2014 |
Peironimev-Plus® in the treatment of chronic inflammation of tunica albuginea (Peyronie's disease). results of a controlled study.
Topics: 4-Aminobenzoic Acid; Adult; Aged; Anthocyanins; Antioxidants; Biological Therapy; Chronic Disease; D | 2013 |
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
Topics: Acetylcholine; Adolescent; Adult; Antioxidants; Biomarkers; Bradykinin; Cross-Over Studies; Double-B | 2007 |
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
Topics: Acetylcholine; Adolescent; Adult; Antioxidants; Biomarkers; Bradykinin; Cross-Over Studies; Double-B | 2007 |
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
Topics: Acetylcholine; Adolescent; Adult; Antioxidants; Biomarkers; Bradykinin; Cross-Over Studies; Double-B | 2007 |
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
Topics: Acetylcholine; Adolescent; Adult; Antioxidants; Biomarkers; Bradykinin; Cross-Over Studies; Double-B | 2007 |
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
Topics: Acetylcholine; Adolescent; Adult; Antioxidants; Biomarkers; Bradykinin; Cross-Over Studies; Double-B | 2007 |
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
Topics: Acetylcholine; Adolescent; Adult; Antioxidants; Biomarkers; Bradykinin; Cross-Over Studies; Double-B | 2007 |
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
Topics: Acetylcholine; Adolescent; Adult; Antioxidants; Biomarkers; Bradykinin; Cross-Over Studies; Double-B | 2007 |
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
Topics: Acetylcholine; Adolescent; Adult; Antioxidants; Biomarkers; Bradykinin; Cross-Over Studies; Double-B | 2007 |
Persistent endothelial dysfunction in humans after diesel exhaust inhalation.
Topics: Acetylcholine; Adolescent; Adult; Antioxidants; Biomarkers; Bradykinin; Cross-Over Studies; Double-B | 2007 |
Inflammatory and hemostatic markers in relation to cardiovascular prognosis in patients with stable angina pectoris. Results from the APSIS study. The Angina Prognosis Study in Stockholm.
Topics: Adrenergic beta-Agonists; Aged; Angina Pectoris; beta-Thromboglobulin; Calcium Channel Blockers; Car | 2000 |
Acute systemic inflammation impairs endothelium-dependent dilatation in humans.
Topics: Acetylcholine; Adult; Analysis of Variance; Bacterial Vaccines; Blood Flow Velocity; Brachial Artery | 2000 |
Acute systemic inflammation impairs endothelium-dependent dilatation in humans.
Topics: Acetylcholine; Adult; Analysis of Variance; Bacterial Vaccines; Blood Flow Velocity; Brachial Artery | 2000 |
Acute systemic inflammation impairs endothelium-dependent dilatation in humans.
Topics: Acetylcholine; Adult; Analysis of Variance; Bacterial Vaccines; Blood Flow Velocity; Brachial Artery | 2000 |
Acute systemic inflammation impairs endothelium-dependent dilatation in humans.
Topics: Acetylcholine; Adult; Analysis of Variance; Bacterial Vaccines; Blood Flow Velocity; Brachial Artery | 2000 |
29 other studies available for verapamil and Inflammation
| Article | Year |
|---|---|
TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
Topics: Amyotrophic Lateral Sclerosis; Animals; Brain; Case-Control Studies; DNA-Binding Proteins; Humans; I | 2022 |
Calcium channel antagonists interfere with the mechanism of action of elastin-derived peptide VGVAPG in mouse cortical astrocytes in vitro.
Topics: Animals; Astrocytes; Calcium Channel Blockers; Dizocilpine Maleate; Elastin; Humans; Inflammation; M | 2022 |
The therapeutic effect of verapamil in lipopolysaccharide-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Inflammation; Inflam | 2019 |
Role of ASM/Cer/TXNIP signaling module in the NLRP3 inflammasome activation.
Topics: Adenosine Triphosphate; Carrier Proteins; Caspase 1; Ceramides; Gene Expression Regulation; Humans; | 2021 |
Hesperetin modulates the Sirt1/Nrf2 signaling pathway in counteracting myocardial ischemia through suppression of oxidative stress, inflammation, and apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Dose-Response Relationship, Drug; Electrocardiography; Heart Funct | 2021 |
Inflammatory cytokines tumour necrosis factor-α and interleukin-8 enhance airway smooth muscle contraction by increasing L-type Ca
Topics: Animals; Calcium; Calcium Channels, L-Type; Extracellular Space; Gene Expression Regulation; Inflamm | 2019 |
The validity of
Topics: Animals; Biomarkers; Biopsy; Blood-Brain Barrier; Brain; Brain Neoplasms; Carbazoles; Fluorine Radio | 2019 |
Verapamil Attenuated Prediabetic Neuropathy in High-Fat Diet-Fed Mice through Inhibiting TXNIP-Mediated Apoptosis and Inflammation.
Topics: Animals; Anti-Arrhythmia Agents; Apoptosis; Carrier Proteins; Diabetes Mellitus, Experimental; Diet, | 2019 |
Studies on tracheorelaxant and anti-inflammatory activities of rhizomes of Polygonatum verticillatum.
Topics: Animals; Anti-Inflammatory Agents; Calcium Channel Blockers; Carbachol; Carrageenan; Edema; Female; | 2013 |
Curine inhibits eosinophil activation and airway hyper-responsiveness in a mouse model of allergic asthma.
Topics: Administration, Oral; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Calcium; Di | 2013 |
Hesperidin alleviates rat postoperative ileus through anti-inflammation and stimulation of Ca(2+)-dependent myosin phosphorylation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Calcium; Cecum; Cyclooxygenase 2; Cytoki | 2016 |
Chronic Calcium Channel Inhibitor Verapamil Antagonizes TNF-α-Mediated Inflammatory Reaction and Protects Against Inflammatory Arthritis in Mice.
Topics: Animals; Arthritis, Experimental; Calcium Channel Blockers; Collagen; Inflammation; Inflammation Med | 2016 |
Tumor necrosis factor alpha increases P-glycoprotein expression in a BME-UV in vitro model of mammary epithelial cells.
Topics: 14-alpha Demethylase Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; A | 2010 |
Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity.
Topics: Animals; Apoptosis; Carrier Proteins; Caspase 3; Caspase Inhibitors; Cell Cycle Proteins; Eye Diseas | 2011 |
Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals.
Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Disease Models, An | 2012 |
Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals.
Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Disease Models, An | 2012 |
Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals.
Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Disease Models, An | 2012 |
Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals.
Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Disease Models, An | 2012 |
Inflammation-induced dysfunction of the low-density lipoprotein receptor-related protein-1 at the blood-brain barrier: protection by the antioxidant N-acetylcysteine.
Topics: Acetylcysteine; Algorithms; alpha-Macroglobulins; Amyloid beta-Peptides; Animals; Antioxidants; Bloo | 2012 |
Bronchodilator activity of aerial parts of Polygonatum verticillatum augmented by anti-inflammatory activity: attenuation of Ca²⁺ channels and lipoxygenase.
Topics: Animals; Anti-Inflammatory Agents; Bronchodilator Agents; Calcium Channel Blockers; Carbachol; Carra | 2013 |
Effect of early phase adjuvant arthritis on hepatic P450 enzymes and pharmacokinetics of verapamil: an alternative approach to the use of an animal model of inflammation for pharmacokinetic studies.
Topics: Administration, Oral; Animals; Arthritis, Experimental; Blood Proteins; Cytochrome P-450 Enzyme Syst | 2005 |
Effects of angiotensin II blockade on inflammation-induced alterations of pharmacokinetics and pharmacodynamics of calcium channel blockers.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; C-Reactive Protein; Calcium Cha | 2008 |
Non-specific activity of (+/-)CP-96,345 in models of pain and inflammation.
Topics: Animals; Biphenyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Hyp | 1993 |
Influence of endotoxin on the stereoselective pharmacokinetics of oxprenolol, propranolol, and verapamil in the rat.
Topics: Animals; Drug Interactions; Endotoxins; Inflammation; Male; Orosomucoid; Oxprenolol; Propranolol; Pr | 1994 |
Regulation of putrescine export in lipopolysaccharide or IFN-gamma-activated murine monocytic-leukemic RAW 264 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; DNA; Dose-Response Relationship, Drug; Eflornithine | 1994 |
Enhancement of anti-inflammatory activity of aspirin by verapamil.
Topics: Adrenal Glands; Animals; Aspirin; Carrageenan; Drug Synergism; Female; Foreign Bodies; Inflammation; | 1993 |
Ca2+ channel blockade by verapamil inhibits GMCs and diarrhea during small intestinal inflammation.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Diarrhea; Dogs; Infla | 1997 |
Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases?
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Chromosomes, Huma | 1998 |
Effects of BRL 55 834 on allergen-induced bronchoconstriction and airway inflammation in sensitized guinea pigs.
Topics: Animals; Asthma; Benzopyrans; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agen | 1999 |
Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Diltiazem; F | 1992 |
[Anti-inflammatory effects of verapamil, nifedipine and nicardipine].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Dinoprostone; Female; Infl | 1990 |
Calcium channel blockers in acute inflammation.
Topics: Animals; Carrageenan; Edema; Female; Foot; Histamine; Hyaluronoglucosaminidase; Inflammation; Male; | 1988 |