Page last updated: 2024-10-24

verapamil and Hypothermia

verapamil has been researched along with Hypothermia in 8 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
"We sought to determine the effects of two different calcium channel antagonists, S-emopamil and nimodipine, on hippocampal glutamate and glycine release and to compare their effects to those of mild hypothermia."7.68Effect of S-emopamil, nimodipine, and mild hypothermia on hippocampal glutamate concentrations after repeated cerebral ischemia in rabbits. ( Matsumoto, M; Scheller, MS; Strnat, MA; Zornow, MH, 1993)
" This hypothesis has been tested by the use of hypothermia, pretreatment with verapamil and a reduced extracellular Ca2+ to modify the events precipitated by an ischemic episode."4.76The role of calcium in the ischemic myocardium. ( Nayler, WG, 1981)
" The Ito agonist NS5806, sodium channel blocker ajmaline, calcium channel blocker verapamil or hypothermia (32°C) were used to pharmacologically mimic the genetic defects and conditions associated with JWS, thus eliciting prominent J waves and provoking VT/VF."3.96Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes. ( Ackerman, MJ; Antzelevitch, C; Barajas-Martinez, H; Borbáth, V; Burashnikov, A; Clatot, J; Di Diego, JM; Hu, D; Li, GR; Patocskai, B; Robinson, VM, 2020)
"We sought to determine the effects of two different calcium channel antagonists, S-emopamil and nimodipine, on hippocampal glutamate and glycine release and to compare their effects to those of mild hypothermia."3.68Effect of S-emopamil, nimodipine, and mild hypothermia on hippocampal glutamate concentrations after repeated cerebral ischemia in rabbits. ( Matsumoto, M; Scheller, MS; Strnat, MA; Zornow, MH, 1993)
" After long-term administration of nifedipine no significant alterations in the central actions of ethanol were observed."1.29Effects of calcium antagonists on central actions of ethanol: comparative studies with nifedipine, verapamil and cinnarizine. ( Czarnecka, E; Kubik-Bogucka, E, 1993)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Di Diego, JM1
Patocskai, B1
Barajas-Martinez, H1
Borbáth, V1
Ackerman, MJ1
Burashnikov, A1
Clatot, J1
Li, GR1
Robinson, VM1
Hu, D1
Antzelevitch, C1
Baker, JE1
Hearse, DJ1
Nayler, WG1
Matsumoto, M1
Scheller, MS1
Zornow, MH1
Strnat, MA1
Czarnecka, E1
Kubik-Bogucka, E1
Volkov, AM1
Kazanskaya, GM1
Chasovskikh, GG1
D'yakonitsa, TM1
Zhdanov, GP1
Lomivorotov, VN1
Domalik-Wawrzynski, LJ1
Powell, WJ1
Guerrero, L1
Palacios, I1
Renwart, N1
Francès, H1
Simon, P1

Reviews

1 review available for verapamil and Hypothermia

ArticleYear
The role of calcium in the ischemic myocardium.
    The American journal of pathology, 1981, Volume: 102, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calcium; Coronary Disease; Cytosol; Hypothermia; Male; Mitochondria

1981

Other Studies

7 other studies available for verapamil and Hypothermia

ArticleYear
Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Ajmaline; Animals; Brugada Syndrome; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Ele

2020
The temperature-sensitivity of slow channel calcium blockers in relation to their effect upon the calcium paradox.
    European heart journal, 1983, Volume: 4 Suppl H

    Topics: Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Hypothermia; Kinetics;

1983
Effect of S-emopamil, nimodipine, and mild hypothermia on hippocampal glutamate concentrations after repeated cerebral ischemia in rabbits.
    Stroke, 1993, Volume: 24, Issue:8

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Glutamates; Glutamic Acid; Hippocampus; Hypotherm

1993
Effects of calcium antagonists on central actions of ethanol: comparative studies with nifedipine, verapamil and cinnarizine.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1993, Volume: 28, Issue:6

    Topics: Adolescent; Animals; Brain; Calcium; Cinnarizine; Drug Tolerance; Ethanol; Humans; Hypothermia; Inje

1993
Effect of calcium antagonists on ultrastructure of myocardial microvessels during open heart surgery under conditions of pharmacological and cold cardioplegia.
    Bulletin of experimental biology and medicine, 2001, Volume: 132, Issue:3

    Topics: Body Temperature; Calcium; Cardiac Surgical Procedures; Child; Cold Temperature; Heart; Heart Arrest

2001
Effect of changes in ventricular relaxation on early diastolic coronary blood flow in canine hearts.
    Circulation research, 1987, Volume: 61, Issue:5

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Diastole; Dogs; Heart Ventricles;

1987
Verapamil's lack of antidopaminergic properties in mice.
    The American journal of psychiatry, 1986, Volume: 143, Issue:7

    Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Hypothermia; Mice; Stereotyped Behavior; Ver

1986