verapamil has been researched along with Hypertrophy in 19 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared the chronic effects in spontaneously hypertensive rats (SHR) of low doses of an angiotensin converting enzyme inhibitor, trandolapril, a Ca2+ channel antagonist, verapamil, and their combination (trandolapril-verapamil), on arterial mechanical properties, arterial wall hypertrophy and extracellular matrix proteins." | 3.70 | Prevention of arterial structural alterations with verapamil and trandolapril and consequences for mechanical properties in spontaneously hypertensive rats. ( Benetos, A; Kirchengaast, M; Koffi, I; Lacolley, P; Laurent, S; Pomiès, JP, 1998) |
| "0%) prevented by the protein synthesis inhibitor cycloheximide (10(-5)M), which supports the role of decreased protein degradation in the angiotensin-II-induced cell hypertrophy." | 3.69 | Angiotensin-II-induced cell hypertrophy: potential role of impaired proteolytic activity in cultured LLC-PK1 cells. ( Heidland, A; Ling, H; Schaefer, L; Schaefer, RM; Schnittler, HJ; Vamvakas, S, 1995) |
| "We performed two sets of experiments in order to prevent or to regress cardiac and vascular hypertrophy, using antihypertensive and subantihypertensive doses of the angiotensin converting enzyme inhibitor zabicipril." | 3.68 | Cardiac and vascular effects of chronic angiotensin converting enzyme inhibition at subantihypertensive doses. ( Gohlke, P; Lamberty, V; Mall, G; Martorana, P; Mattfeld, T; Stoll, M; Unger, T; van Even, P, 1992) |
| "The effect of long-term treatment with either enalapril or high dose verapamil on survival, proteinuria, blood pressure and renal morphology was studied in female Wistar rats with markedly reduced renal mass." | 3.67 | Long-term enalapril and verapamil in rats with reduced renal mass. ( Bock, HA; Brunner, FP; Hermle, M; Mihatsch, MJ; Thiel, G, 1989) |
| "Different approaches are used aiming to improve these scars, including intralesional corticosteroids, surgery and more recently, laser therapy." | 2.82 | Laser therapy for treating hypertrophic and keloid scars. ( da Silva, CA; da Silva, EM; Kuczynski, U; Leszczynski, R; Pinto, ACPN, 2022) |
| "The 2 patients with recurrences are now successfully treated with a calcium channel blocker, an approach, to our knowledge, never before reported for adult-onset nesidioblastosis." | 2.41 | Adult-onset nesidioblastosis causing hypoglycemia: an important clinical entity and continuing treatment dilemma. ( Costa, EA; Kaplan, EL; Koka, MR; Straus II, FH; Sugg, SL; Witteles, RM, 2001) |
| "Hypertrophic cardiomyopathy is associated with the human lymphocyte antigen (HLA DR3), and this may provide a possible link with SSc, as this HLA phenotype is common in the latter condition." | 1.33 | Hypertrophic cardiomyopathy in systemic sclerosis. A report of two cases. ( Anastasiadis, G; Moyssakis, I; Papadopoulos, DP; Vlachoyannopoulos, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 11 (57.89) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Leszczynski, R | 1 |
| da Silva, CA | 1 |
| Pinto, ACPN | 1 |
| Kuczynski, U | 1 |
| da Silva, EM | 1 |
| Choi, J | 1 |
| Han, YN | 1 |
| Rha, EY | 1 |
| Kang, HJ | 1 |
| Kim, KJ | 1 |
| Park, IK | 1 |
| Kim, HJ | 1 |
| Rhie, JW | 1 |
| Wu, G | 1 |
| Wang, H | 1 |
| Yang, J | 1 |
| Yang, Y | 1 |
| Liu, C | 1 |
| Jing, L | 1 |
| Wong, TM | 1 |
| Griffin, KA | 2 |
| Picken, M | 1 |
| Giobbie-Hurder, A | 1 |
| Bidani, AK | 2 |
| Moyssakis, I | 1 |
| Papadopoulos, DP | 1 |
| Anastasiadis, G | 1 |
| Vlachoyannopoulos, P | 1 |
| Schild, L | 1 |
| Bukowska, A | 1 |
| Gardemann, A | 1 |
| Polczyk, P | 1 |
| Keilhoff, G | 1 |
| Täger, M | 1 |
| Dudley, SC | 1 |
| Klein, HU | 1 |
| Goette, A | 1 |
| Lendeckel, U | 1 |
| Sigwart, U | 1 |
| Johnson, TB | 1 |
| Kent, RL | 1 |
| Bubolz, BA | 1 |
| McDermott, PJ | 1 |
| Johnson, PL | 1 |
| Bhattacharya, SK | 1 |
| Ling, H | 1 |
| Vamvakas, S | 1 |
| Schaefer, L | 1 |
| Schnittler, HJ | 1 |
| Schaefer, RM | 1 |
| Heidland, A | 1 |
| Doggrell, SA | 1 |
| Surman, AJ | 1 |
| Koffi, I | 1 |
| Lacolley, P | 1 |
| Kirchengaast, M | 1 |
| Pomiès, JP | 1 |
| Laurent, S | 1 |
| Benetos, A | 1 |
| O'Brien, TX | 1 |
| Schuyler, GT | 1 |
| Rackley, MS | 1 |
| Thompson, JT | 1 |
| Picken, MM | 1 |
| Bakris, GL | 1 |
| Witteles, RM | 1 |
| Straus II, FH | 1 |
| Sugg, SL | 1 |
| Koka, MR | 1 |
| Costa, EA | 1 |
| Kaplan, EL | 1 |
| Gohlke, P | 1 |
| Stoll, M | 1 |
| Lamberty, V | 1 |
| Mattfeld, T | 1 |
| Mall, G | 1 |
| van Even, P | 1 |
| Martorana, P | 1 |
| Unger, T | 1 |
| Ikeda, U | 1 |
| Tsuruya, Y | 1 |
| Yaginuma, T | 1 |
| Wight, JP | 1 |
| Bassett, AH | 1 |
| Le Carpentier, JE | 1 |
| el Nahas, AM | 1 |
| Brunner, FP | 1 |
| Thiel, G | 1 |
| Hermle, M | 1 |
| Bock, HA | 1 |
| Mihatsch, MJ | 1 |
2 reviews available for verapamil and Hypertrophy
| Article | Year |
|---|---|
Laser therapy for treating hypertrophic and keloid scars.
Topics: Adrenal Cortex Hormones; Adult; Aluminum; Atrophy; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Di | 2022 |
Adult-onset nesidioblastosis causing hypoglycemia: an important clinical entity and continuing treatment dilemma.
Topics: Adult; Age of Onset; Calcium Channel Blockers; Combined Modality Therapy; Diabetes Mellitus, Type 1; | 2001 |
17 other studies available for verapamil and Hypertrophy
| Article | Year |
|---|---|
Verapamil-containing silicone gel reduces scar hypertrophy.
Topics: Animals; Cicatrix, Hypertrophic; Collagen; Hypertrophy; Rabbits; Silicone Gels; Verapamil | 2021 |
kappa-Opioid receptor stimulation inhibits augmentation of Ca(2+) transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes - Role of CaMKIIdelta(B).
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic | 2008 |
Low protein diet mediated renoprotection in remnant kidneys: Renal autoregulatory versus hypertrophic mechanisms.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Cytoprotection; Diet, Protein-Restric | 2003 |
Hypertrophic cardiomyopathy in systemic sclerosis. A report of two cases.
Topics: Aged; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Echocardiography; Female; Heart Septum; | 2006 |
Rapid pacing of embryoid bodies impairs mitochondrial ATP synthesis by a calcium-dependent mechanism--a model of in vitro differentiated cardiomyocytes to study molecular effects of tachycardia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cardiac Pa | 2006 |
Non-surgical myocardial reduction for hypertrophic obstructive cardiomyopathy.
Topics: Aged; Angioplasty, Balloon, Coronary; Blood Pressure; Cardiac Catheterization; Cardiomyopathy, Hyper | 1995 |
Electrical stimulation of contractile activity accelerates growth of cultured neonatal cardiocytes.
Topics: Animals; Animals, Newborn; Base Sequence; Cell Division; Cells, Cultured; Contractile Proteins; Diac | 1994 |
Regulation of membrane-mediated chronic muscle degeneration in dystrophic hamsters by calcium-channel blockers: diltiazem, nifedipine and verapamil.
Topics: Animals; Body Weight; Calcium; Calcium Channel Blockers; Cardiomegaly; Creatine Kinase; Cricetinae; | 1993 |
Angiotensin-II-induced cell hypertrophy: potential role of impaired proteolytic activity in cultured LLC-PK1 cells.
Topics: Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Calcium; Calcium Channel Blockers | 1995 |
Loss of maximum attenuation and receptor reserve for isoprenaline at the beta 2-adrenoceptors of the portal veins of hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Hypertension; Hypertroph | 1995 |
Prevention of arterial structural alterations with verapamil and trandolapril and consequences for mechanical properties in spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antigens, CD; Aorta, Thoracic; Arteries; Blood Pr | 1998 |
F1-ATP synthase beta-subunit and cytochrome c transcriptional regulation in right ventricular hemodynamic overload and hypertrophically stimulated cardiocytes.
Topics: 3T3 Cells; Animals; beta-Galactosidase; Cats; Cell Culture Techniques; Cytochrome c Group; Female; G | 1999 |
Class differences in the effects of calcium channel blockers in the rat remnant kidney model.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Disease Models, Animal; Drinking; Felo | 1999 |
Cardiac and vascular effects of chronic angiotensin converting enzyme inhibition at subantihypertensive doses.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bridged Bicyclo Compounds; Brid | 1992 |
Alpha 1-adrenergic stimulation is coupled to cardiac myocyte hypertrophy.
Topics: Animals; Cells, Cultured; Heart Ventricles; Hypertrophy; Leucine; Myocardium; Norepinephrine; Potass | 1991 |
Effect of treatment with enalapril, verapamil and indomethacin on compensatory renal growth in the rat.
Topics: Animals; Body Weight; Enalapril; Hypertrophy; Indomethacin; Kidney; Male; Nephrectomy; Organ Size; R | 1990 |
Long-term enalapril and verapamil in rats with reduced renal mass.
Topics: Animals; Enalapril; Female; Glomerulonephritis; Hypertension, Renal; Hypertrophy; Kidney; Nephrectom | 1989 |