verapamil has been researched along with Hypertension, Renal in 38 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Monotherapy with calcium antagonists nifedipine, foridon and verapamil hydrochloride was assessed in 46 patients with chronic glomerulonephritis and arterial hypertension by hypotensive effect and changes in systemic and renal hemodynamics, water-electrolytic balance, renin-angiotensin system." | 5.06 | [Calcium antagonists in the treatment of nephrogenic hypertension]. ( Galstian, GM; Kutyrina, IM; Rogov, VA; Tareeva, IE, 1990) |
| "The effects of verapamil or diltiazem on pressor responses to posterior hypothalamic stimulation, injected noradrenaline or tyramine were studied in urethane-anaesthetized normotensive, deoxycorticosterone acetate (DOCA), renal and spontaneously hypertensive rats at the early and established phases of hypertension." | 3.68 | Failure of verapamil and diltiazem to attenuate the pressor response to hypothalamic stimulation: a possible mechanism. ( Eferakeya, AE; Osunkwo, UA, 1992) |
| "The effect of long-term treatment with either enalapril or high dose verapamil on survival, proteinuria, blood pressure and renal morphology was studied in female Wistar rats with markedly reduced renal mass." | 3.67 | Long-term enalapril and verapamil in rats with reduced renal mass. ( Bock, HA; Brunner, FP; Hermle, M; Mihatsch, MJ; Thiel, G, 1989) |
| " An increased pressor responsiveness to noradrenaline was indicated by a shift of the noradrenaline dose-response curve to the left in group A rats as compared with group C rats." | 1.27 | Vascular hypersensitivity to noradrenaline: a possible mechanism of hypertension in rats with chronic uraemia. ( Chaichenco, Y; Chaimovitz, C; Goligorsky, M; Kaplanski, J; Rapoport, J; Zimlichman, RR, 1984) |
| "Verapamil has a lowering effect on the blood pressure even in the presence of advanced renal failure." | 1.26 | [The treatment of renal hypertension with verapamil in childhood (author's transl]. ( Alatas, H; Bein, G; Schärer, K, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (68.42) | 18.7374 |
| 1990's | 10 (26.32) | 18.2507 |
| 2000's | 2 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BECKER, G | 1 |
| SCHNEIDER, KW | 1 |
| JACOB, KO | 1 |
| Garcia, R | 1 |
| Schiffrin, EL | 1 |
| Thibault, G | 1 |
| Boucher, R | 1 |
| Genest, J | 1 |
| Zimlichman, RR | 1 |
| Chaimovitz, C | 1 |
| Chaichenco, Y | 1 |
| Goligorsky, M | 1 |
| Rapoport, J | 1 |
| Kaplanski, J | 1 |
| Alves Filho, G | 1 |
| Saragoça, MA | 1 |
| Ribeiro, AB | 1 |
| Ramos, OL | 1 |
| Vasques, EC | 1 |
| Mill, JG | 1 |
| Moysés, MR | 1 |
| da Silva, FD | 1 |
| da Costa, MB | 1 |
| Caldas, JG | 1 |
| Cabral, Ade M | 1 |
| Vassalo, DV | 1 |
| Schohn, DC | 1 |
| Jahn, HA | 1 |
| Maareck, M | 1 |
| Torralbo, A | 1 |
| Trobo, JI | 1 |
| Borque, M | 1 |
| Herrero, JA | 1 |
| Velasco, E | 1 |
| Marcello, M | 1 |
| González-Mate, A | 1 |
| Barrientos, A | 1 |
| Reams, GP | 1 |
| Llinás, MT | 1 |
| González, JD | 1 |
| Salazar, FJ | 1 |
| Martínez-Castelao, A | 1 |
| Hueso, M | 1 |
| Sanz, V | 1 |
| Rejas, J | 1 |
| Alsina, J | 1 |
| Grinyó, JM | 1 |
| Griffin, KA | 1 |
| Picken, MM | 1 |
| Bakris, GL | 1 |
| Bidani, AK | 1 |
| Meyer-Lehnert, H | 1 |
| Bäcker, A | 1 |
| Kramer, HJ | 1 |
| Nicita-Mauro, V | 1 |
| Barbera, N | 1 |
| Savica, V | 1 |
| Frisina, N | 1 |
| Ceruso, D | 1 |
| Hepp, A | 1 |
| Maisch, B | 1 |
| Raff, U | 1 |
| Hayduk, K | 1 |
| Haas, Th | 1 |
| Denkl, P | 1 |
| Schärer, K | 1 |
| Alatas, H | 1 |
| Bein, G | 1 |
| Eferakeya, AE | 1 |
| Osunkwo, UA | 1 |
| Gurgenian, SV | 1 |
| Mikaelian, ES | 1 |
| Dzhandzhapanian, AZ | 1 |
| Babaian, AS | 1 |
| Tareeva, IE | 1 |
| Kutyrina, IM | 1 |
| Galstian, GM | 1 |
| Rogov, VA | 1 |
| Inscho, EW | 1 |
| Carmines, PK | 1 |
| Cook, AK | 1 |
| Navar, LG | 1 |
| Myers, JH | 1 |
| Lamb, FS | 1 |
| Webb, RC | 1 |
| Steele, TH | 1 |
| Challoner-Hue, L | 1 |
| Eiskjaer, H | 2 |
| Pedersen, EB | 2 |
| Rasmussen, LM | 2 |
| Jespersen, B | 2 |
| Brunner, FP | 1 |
| Thiel, G | 1 |
| Hermle, M | 1 |
| Bock, HA | 1 |
| Mihatsch, MJ | 1 |
| Barr, SM | 1 |
| Hamilton, CA | 2 |
| Reid, JL | 2 |
| Ogborn, MR | 1 |
| Crocker, JF | 1 |
| Grimm, PC | 1 |
| Jardine, E | 1 |
| Sumner, DJ | 1 |
| Miller, FN | 1 |
| Joshua, IG | 1 |
| Fleming, JT | 1 |
| Parekh, N | 1 |
| Loeb, AL | 1 |
| Bean, BL | 1 |
| Boero, R | 1 |
| Quarello, F | 1 |
| Guarena, C | 1 |
| Piccoli, G | 1 |
| Marmo, E | 1 |
| Cameron, JS | 1 |
| Miller, LS | 1 |
| Kimura, S | 1 |
| Kaiser, CJ | 1 |
| Campbell, DR | 1 |
| Kozlovskis, PL | 1 |
| Gaide, MS | 1 |
| Myerburg, RJ | 1 |
| Bassett, AL | 1 |
| Dieckmann, L | 1 |
| Hösemann, R | 1 |
| Brittinger, WD | 1 |
| Schwarzbeck, A | 1 |
| Wittenmeier, KW | 2 |
| Twittenhoff, WD | 2 |
| Stegaru, B | 1 |
| Huber, W | 2 |
| Ewald, RW | 1 |
| von Henning, GE | 2 |
| Fabricius, M | 1 |
| Strauch, M | 2 |
| Schmitt, G | 1 |
| Brittinger, DW | 1 |
| Koch, WD | 1 |
1 review available for verapamil and Hypertension, Renal
| Article | Year |
|---|---|
Do calcium channel blockers have renal protective effects?
Topics: Aging; Animals; Calcium Channel Blockers; Clinical Trials as Topic; Cyclosporine; Diabetic Nephropat | 1994 |
3 trials available for verapamil and Hypertension, Renal
| Article | Year |
|---|---|
Long term effects of sustained release verapamil on the renal and systemic haemodynamic parameters in hypertensive patients with mild to severe chronic renal failure.
Topics: Delayed-Action Preparations; Electrolytes; Female; Heart Function Tests; Hemodynamics; Hormones; Hum | 1993 |
Treatment of hypertension after renal transplantation: long-term efficacy of verapamil, enalapril, and doxazosin.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Doxazosin; Enalapril; Female; Follow-Up St | 1998 |
[Calcium antagonists in the treatment of nephrogenic hypertension].
Topics: Adolescent; Adult; Calcium Channel Blockers; Glomerulonephritis; Hemodynamics; Humans; Hypertension, | 1990 |
34 other studies available for verapamil and Hypertension, Renal
| Article | Year |
|---|---|
[CHANGES IN RENAL HEMODYNAMICS UNDER THE INFLUENCE OF D-365 AND USING I-131-LABELED HIPPURAN AS AN INDICATOR].
Topics: Blood Circulation; Blood Volume Determination; Hemodynamics; Hypertension; Hypertension, Renal; Iodi | 1965 |
Effects of tonin on vascular smooth muscle of the hypertensive rat and normal rabbit.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Hypertension, Renal; Hypertension, Renovascular; I | 1980 |
Vascular hypersensitivity to noradrenaline: a possible mechanism of hypertension in rats with chronic uraemia.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Hemodynamics; Hypertension, Renal; Male; | 1984 |
[Immediate and intermediate effects of verapamil administration in rats with experimental renal hypertension].
Topics: Animals; Blood Pressure; Disease Models, Animal; Hemodynamics; Hypertension, Renal; Male; Rats; Rats | 1982 |
[Effects of verapamil on arterial blood pressure and heart rate in awake animals with neurogenic and renal hypertension].
Topics: Animals; Blood Pressure; Disease Models, Animal; Heart Rate; Hypertension; Hypertension, Renal; Infu | 1982 |
Alterations in renal endothelin production in rats with reduced renal mass.
Topics: Animals; Enalapril; Endothelins; Erythropoietin; Hypertension, Renal; Kidney; Kidney Diseases; Male; | 1995 |
Effects of verapamil on the renal actions induced by nitric oxide and prostaglandin synthesis inhibition.
Topics: Animals; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Dogs; Enzyme Inhibitors; Hypertension, | 1996 |
Class differences in the effects of calcium channel blockers in the rat remnant kidney model.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Disease Models, Animal; Drinking; Felo | 1999 |
Inhibitors of Na-K-ATPase in human urine: effects of ouabain-like factors and of vanadium-diascorbate on calcium mobilization in rat vascular smooth muscle cells: comparison with the effects of ouabain, angiotensin II, and arginine-vasopressin.
Topics: Adult; Angiotensin II; Animals; Aorta, Thoracic; Arginine Vasopressin; Ascorbic Acid; Biological Fac | 2000 |
[Accomplishing 2 goals at once. Nephropathy and cardiac risk].
Topics: Antihypertensive Agents; Coronary Disease; Diabetes Mellitus, Type 2; Drug Combinations; Humans; Hyp | 2000 |
[Treatment of hypertensive crises with calcium antagonists].
Topics: Antihypertensive Agents; Calcium; Drug Therapy, Combination; Humans; Hypertension; Hypertension, Ren | 1978 |
[Comparative studies with propranolol, verapamil and atenolol in hypertensive dialysis patients].
Topics: Atenolol; Humans; Hypertension, Renal; Kidney Failure, Chronic; Propanolamines; Propranolol; Renal D | 1977 |
[Therapy of hypertensive crises].
Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine | 1977 |
[The treatment of renal hypertension with verapamil in childhood (author's transl].
Topics: Administration, Oral; Adolescent; Arrhythmias, Cardiac; Child; Child, Preschool; Female; Humans; Hyp | 1977 |
Failure of verapamil and diltiazem to attenuate the pressor response to hypothalamic stimulation: a possible mechanism.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Desoxycorticosterone; Diltiazem; Electric Stimulation; Fem | 1992 |
Efficacy of intravenous verapamil in arterial hypertension refractory to three-step antihypertensive therapy.
Topics: Adult; Antihypertensive Agents; Clonidine; Echocardiography; Female; Hemodynamics; Humans; Hydrochlo | 1991 |
Afferent arteriolar responsiveness to altered perfusion pressure in renal hypertension.
Topics: Animals; Arterioles; Blood; Hypertension, Renal; Nitroprusside; Perfusion; Pressure; Rats; Renal Cir | 1990 |
Contractile responses to ouabain and potassium-free solution in vascular tissue from renal hypertensive rats.
Topics: Animals; Buffers; Calcium; Hypertension, Renal; Ion Channels; Isotonic Solutions; Male; Muscle Contr | 1987 |
Dihydropyridine calcium antagonists and agonists in the isolated perfused Dahl rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
Verapamil sustained-release in renal parenchymal hypertension: effect on blood pressure, kidney function, angiotensin II, aldosterone, arginine vasopressin, atrial natriuretic peptide, and lipoproteins.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; | 1989 |
Long-term enalapril and verapamil in rats with reduced renal mass.
Topics: Animals; Enalapril; Female; Glomerulonephritis; Hypertension, Renal; Hypertrophy; Kidney; Nephrectom | 1989 |
Platelet cytosolic free calcium before and after antihypertensive treatment in perinephritis hypertension of the rabbit.
Topics: Adrenergic alpha-Agonists; Animals; Blood Platelets; Blood Pressure; Calcium; Calcium Channels; Cyto | 1989 |
Nifedipine, verapamil and cyclosporin A pharmacokinetics in children.
Topics: Child; Child, Preschool; Cyclosporins; Drug Interactions; Humans; Hypertension, Renal; Kidney Transp | 1989 |
The effects of calcium antagonists on blood pressure and responses to alpha-adrenoceptor agonists in hypertensive rabbits.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Drug Interac | 1987 |
Sustained release verapamil in renal hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; | 1988 |
Histamine-induced protein leakage in hypertensive rats: inhibition by verapamil.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Fluorescein-5-isothiocyanate; Fluorescein | 1986 |
Antihypertensive drugs inhibit hypertension-associated aortic DNA synthesis in the rat.
Topics: Animals; Antihypertensive Agents; Captopril; DNA; Female; Hydralazine; Hypertension; Hypertension, R | 1986 |
Verapamil in arterial hypertension with renal disease.
Topics: Adult; Female; Humans; Hypertension, Renal; Kidney Diseases; Male; Middle Aged; Verapamil | 1986 |
On the mechanism of the anti-hypertensive effect of Ca++-blockers.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dogs; Heart | 1986 |
Systemic hypertension induces disparate localized left ventricular action potential lengthening and altered sensitivity to verapamil in left ventricular myocardium.
Topics: Action Potentials; Animals; Cardiomyopathies; Cats; Electric Stimulation; Female; Heart Conduction S | 1986 |
[Antihypertensive effect of verapamil. Studies on and experiences with children].
Topics: Administration, Oral; Adolescent; Blood Pressure Determination; Child; Child, Preschool; Dose-Respon | 1974 |
[Clinical experimental studies on the blood pressure reducing effect of verapamil].
Topics: Adult; Anti-Arrhythmia Agents; Blood Circulation; Blood Pressure; Electrocardiography; Female; Femor | 1970 |
[On the protective effect of iproveratil in myocardial diseases due to hypertension in animal experiment].
Topics: Animals; Anti-Arrhythmia Agents; Electrocardiography; Heart Diseases; Hypertension, Renal; Hypoxia; | 1967 |
[Iproveratril as an antihypertensive agents in critical renal hypertension].
Topics: Adult; Anti-Arrhythmia Agents; Blood Pressure; Female; Humans; Hypertension, Renal; Infusions, Paren | 1969 |