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verapamil and Hyperpotassemia

verapamil has been researched along with Hyperpotassemia in 20 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"Renal failure patients with baseline mild hyperkalaemia are particularly liable to bradyarrhythmias with SR verapamil."7.78Junctional bradycardia with verapamil in renal failure--care required even with mild hyperkalaemia. ( Al-Mutairi, S; Aldabie, G; El Sayed, A; Hegazi, MO, 2012)
"Verapamil can produce depression of left ventricular function, delayed atrioventricular conduction, and hypotension, which can be potentiated by hyperkalemia."7.68Effect of hyperkalemia on myocardial depression by verapamil in isolated hearts. ( Boyd, SG; Jolly, SR; Mehta, P; Movahed, A; Reeves, WC; Wilson, VP, 1993)
" Common factors were hyperkalemia and verapamil therapy."7.68Effect of hyperkalemia on experimental myocardial depression by verapamil. ( Jolly, SR; Keaton, N; Movahed, A; Reeves, WC; Rose, GC, 1991)
" Using ECG evidence for severe hyperkalemia, the halothane-anesthetized dogs were rendered acutely hyperkalemic to similar plasma levels of K+ (K+ = 8."7.67Verapamil worsens rate of development and hemodynamic effects of acute hyperkalemia in halothane-anesthetized dogs: effects of calcium therapy. ( Moyer, TP; Nugent, M; Tinker, JH, 1984)
"Renal failure patients with baseline mild hyperkalaemia are particularly liable to bradyarrhythmias with SR verapamil."3.78Junctional bradycardia with verapamil in renal failure--care required even with mild hyperkalaemia. ( Al-Mutairi, S; Aldabie, G; El Sayed, A; Hegazi, MO, 2012)
"The effects of the L-type (nifedipine and verapamil) and the T-type (mibefradil) Ca2+ channel blockers on the increase in intracellular Ca2+ concentration ([Ca2+]i) induced by NaCN metabolic inhibition and hyperkalemia were examined in chicken cardiomyocytes using fluorescence imaging with Fura-2."3.70Effects of Ca2+ channel blockers on Ca2+ loading induced by metabolic inhibition and hyperkalemia in cardiomyocytes. ( Duffield, R; Ho, AK; Tang, T, 1998)
"For the evaluation of the hemodynamic interaction between the natural heart and an assist device, a reversible pharmacological model based on the channel blocker Verapamil under hyperkalemia, was developed for deterioration of left ventricular function."3.69Pharmacologically induced heart failure for the evaluation of circulatory assistance. ( Losert, U; Roschal, K; Schima, H; Schmidt, C; Schwendenwein, I; Wieselthaler, G; Wolner, E, 1996)
"Verapamil can produce depression of left ventricular function, delayed atrioventricular conduction, and hypotension, which can be potentiated by hyperkalemia."3.68Effect of hyperkalemia on myocardial depression by verapamil in isolated hearts. ( Boyd, SG; Jolly, SR; Mehta, P; Movahed, A; Reeves, WC; Wilson, VP, 1993)
" Common factors were hyperkalemia and verapamil therapy."3.68Effect of hyperkalemia on experimental myocardial depression by verapamil. ( Jolly, SR; Keaton, N; Movahed, A; Reeves, WC; Rose, GC, 1991)
" Using ECG evidence for severe hyperkalemia, the halothane-anesthetized dogs were rendered acutely hyperkalemic to similar plasma levels of K+ (K+ = 8."3.67Verapamil worsens rate of development and hemodynamic effects of acute hyperkalemia in halothane-anesthetized dogs: effects of calcium therapy. ( Moyer, TP; Nugent, M; Tinker, JH, 1984)
"In vitro prospective, repeated-measures, dose-response study."1.29Effect of calcium to reverse the electrocardiographic effects of hyperkalemia in the isolated rat heart: a prospective, dose-response study. ( Bisogno, JL; Langley, A; Von Dreele, MM, 1994)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19908 (40.00)18.7374
1990's10 (50.00)18.2507
2000's1 (5.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hegazi, MO1
Aldabie, G1
Al-Mutairi, S1
El Sayed, A1
Letavernier, E1
Couzi, L1
Delmas, Y1
Moreau, K1
Murcott, O1
de Précigout, V1
Nugent, M1
Tinker, JH1
Moyer, TP1
Saltzman, LS1
Kates, RA1
Corke, BC1
Norfleet, EA1
Heath, KR1
Waeber, B1
Brunner, HR1
Gilmour, RF1
Zipes, DP1
O'Neill, M1
Ryan, DM1
Paterson, DJ1
Patel, R1
Lipper, B1
Schwartzbard, A1
Nelson, C1
O'Connor, MA1
Frishman, W1
Bisogno, JL1
Langley, A1
Von Dreele, MM1
Jolly, SR2
Wilson, VP1
Movahed, A2
Mehta, P1
Boyd, SG1
Reeves, WC2
Schmidt, C1
Schwendenwein, I1
Wieselthaler, G1
Roschal, K1
Schima, H1
Losert, U1
Wolner, E1
Tang, T2
Duffield, R2
Ho, AK2
Dong, C1
Pacini, DJ1
Boachie-Ansah, G1
Kane, KA1
Reverte, M1
García-Barrado, MJ1
Moratinos, J1
Keaton, N1
Rose, GC1
San Juan, AC1
Wong, KC1
Port, JD1
Rubin, AS1
Zablocki, AD1
Reddy, GV1
Schamroth, L1
Schamroth, CL1
Bender, F1
Reploh, HD1

Reviews

1 review available for verapamil and Hyperpotassemia

ArticleYear
[New therapeutic approaches to arterial hypertension].
    Schweizerische medizinische Wochenschrift, 1982, Sep-25, Volume: 112, Issue:39

    Topics: Angiotensin II; Benzothiadiazines; Calcium; Calcium Channel Blockers; Captopril; Diuretics; Drug The

1982

Other Studies

19 other studies available for verapamil and Hyperpotassemia

ArticleYear
Junctional bradycardia with verapamil in renal failure--care required even with mild hyperkalaemia.
    Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:6

    Topics: Aged; Bradycardia; Calcium Channel Blockers; Delayed-Action Preparations; Female; Humans; Hyperkalem

2012
Verapamil and mild hyperkalemia in hemodialysis patients: a potentially hazardous association.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2006, Volume: 10, Issue:2

    Topics: Blood Chemical Analysis; Follow-Up Studies; Heart Block; Humans; Hyperkalemia; Kidney Failure, Chron

2006
Verapamil worsens rate of development and hemodynamic effects of acute hyperkalemia in halothane-anesthetized dogs: effects of calcium therapy.
    Anesthesiology, 1984, Volume: 60, Issue:5

    Topics: Acute Disease; Anesthesia, Inhalation; Animals; Blood Pressure; Calcium; Carbon Dioxide; Cardiac Out

1984
Hyperkalemia and cardiovascular collapse after verapamil and dantrolene administration in swine.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:5

    Topics: Animals; Dantrolene; Drug Evaluation, Preclinical; Drug Interactions; Electric Stimulation; Heart Ar

1984
Different electrophysiological responses of canine endocardium and epicardium to combined hyperkalemia, hypoxia, and acidosis.
    Circulation research, 1980, Volume: 46, Issue:6

    Topics: Acidosis; Action Potentials; Animals; Dogs; Electrophysiology; Endocardium; Hyperkalemia; Hypoxia; M

1980
Effect of verapamil on restoration of cardiac performance in raised [K+]o by adrenergic stimulation in the rabbit.
    Acta physiologica Scandinavica, 1995, Volume: 154, Issue:3

    Topics: Action Potentials; Animals; Blood Gas Analysis; Cardiotonic Agents; Female; Hydrogen-Ion Concentrati

1995
Toxic effects of diltiazem in a patient with chronic renal failure.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:3

    Topics: Acidosis; Adult; Diltiazem; Heart Failure; Humans; Hyperkalemia; Hypotension; Kidney Failure, Chroni

1994
Effect of calcium to reverse the electrocardiographic effects of hyperkalemia in the isolated rat heart: a prospective, dose-response study.
    Critical care medicine, 1994, Volume: 22, Issue:4

    Topics: Animals; Calcimycin; Calcium; Dose-Response Relationship, Drug; Electrocardiography; Heart; Heart Ra

1994
Effect of hyperkalemia on myocardial depression by verapamil in isolated hearts.
    Pharmacology, 1993, Volume: 47, Issue:5

    Topics: Animals; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hea

1993
Pharmacologically induced heart failure for the evaluation of circulatory assistance.
    Artificial organs, 1996, Volume: 20, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Cattle;

1996
Effects of Ca2+ channel blockers on Ca2+ loading induced by metabolic inhibition and hyperkalemia in cardiomyocytes.
    European journal of pharmacology, 1998, Nov-06, Volume: 360, Issue:2-3

    Topics: Animals; Benzimidazoles; Calcium; Calcium Channel Blockers; Cells, Cultured; Chickens; Cyanides; Hyp

1998
Protection of cardiomyocytes by pinacidil during metabolic inhibition and hyperkalemia.
    European journal of pharmacology, 1999, Jul-02, Volume: 376, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Bepridil; Calcium; Calcium Channel Blockers; Cells, Cultured; Chick

1999
Modification by hypoxia, hyperkalaemia and acidosis of the cardiac electrophysiological effects of a range of antiarrhythmic drugs.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: Acidosis; Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Ele

1992
Role of alpha-adrenoceptors in control of plasma potassium in conscious rabbits.
    Journal of autonomic pharmacology, 1991, Volume: 11, Issue:5

    Topics: Animals; Apamin; Calcium Channels; Clonidine; Dioxanes; Ethanolamines; Hyperkalemia; Idazoxan; Potas

1991
Effect of hyperkalemia on experimental myocardial depression by verapamil.
    American heart journal, 1991, Volume: 121, Issue:2 Pt 1

    Topics: Acute Disease; Animals; Bradycardia; Calcium; Depression, Chemical; Disease Models, Animal; Dogs; Dr

1991
Hyperkalemia after dantrolene and verapamil-dantrolene administration in dogs.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:8

    Topics: Animals; Blood Pressure; Calcium; Cardiac Output; Dantrolene; Dogs; Drug Interactions; Heart Rate; H

1988
Hyperkalemia, verapamil, and dantrolene.
    Anesthesiology, 1987, Volume: 66, Issue:2

    Topics: Colectomy; Colonic Neoplasms; Coronary Disease; Dantrolene; Drug Interactions; Humans; Hyperkalemia;

1987
Tall and peaked U waves in hypokalemia.
    Chest, 1987, Volume: 91, Issue:4

    Topics: Adult; Aged; Alcoholic Intoxication; Diagnosis, Differential; Electrocardiography; Humans; Hyperkale

1987
[Management of ventricular tachycardias using Isoptin].
    Medizinische Klinik, 1968, May-03, Volume: 63, Issue:18

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; Hyperkalemia; Inject

1968