verapamil has been researched along with Hyperkalemia in 20 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Renal failure patients with baseline mild hyperkalaemia are particularly liable to bradyarrhythmias with SR verapamil." | 7.78 | Junctional bradycardia with verapamil in renal failure--care required even with mild hyperkalaemia. ( Al-Mutairi, S; Aldabie, G; El Sayed, A; Hegazi, MO, 2012) |
| "Verapamil can produce depression of left ventricular function, delayed atrioventricular conduction, and hypotension, which can be potentiated by hyperkalemia." | 7.68 | Effect of hyperkalemia on myocardial depression by verapamil in isolated hearts. ( Boyd, SG; Jolly, SR; Mehta, P; Movahed, A; Reeves, WC; Wilson, VP, 1993) |
| " Common factors were hyperkalemia and verapamil therapy." | 7.68 | Effect of hyperkalemia on experimental myocardial depression by verapamil. ( Jolly, SR; Keaton, N; Movahed, A; Reeves, WC; Rose, GC, 1991) |
| " Using ECG evidence for severe hyperkalemia, the halothane-anesthetized dogs were rendered acutely hyperkalemic to similar plasma levels of K+ (K+ = 8." | 7.67 | Verapamil worsens rate of development and hemodynamic effects of acute hyperkalemia in halothane-anesthetized dogs: effects of calcium therapy. ( Moyer, TP; Nugent, M; Tinker, JH, 1984) |
| "Renal failure patients with baseline mild hyperkalaemia are particularly liable to bradyarrhythmias with SR verapamil." | 3.78 | Junctional bradycardia with verapamil in renal failure--care required even with mild hyperkalaemia. ( Al-Mutairi, S; Aldabie, G; El Sayed, A; Hegazi, MO, 2012) |
| "The effects of the L-type (nifedipine and verapamil) and the T-type (mibefradil) Ca2+ channel blockers on the increase in intracellular Ca2+ concentration ([Ca2+]i) induced by NaCN metabolic inhibition and hyperkalemia were examined in chicken cardiomyocytes using fluorescence imaging with Fura-2." | 3.70 | Effects of Ca2+ channel blockers on Ca2+ loading induced by metabolic inhibition and hyperkalemia in cardiomyocytes. ( Duffield, R; Ho, AK; Tang, T, 1998) |
| "For the evaluation of the hemodynamic interaction between the natural heart and an assist device, a reversible pharmacological model based on the channel blocker Verapamil under hyperkalemia, was developed for deterioration of left ventricular function." | 3.69 | Pharmacologically induced heart failure for the evaluation of circulatory assistance. ( Losert, U; Roschal, K; Schima, H; Schmidt, C; Schwendenwein, I; Wieselthaler, G; Wolner, E, 1996) |
| "Verapamil can produce depression of left ventricular function, delayed atrioventricular conduction, and hypotension, which can be potentiated by hyperkalemia." | 3.68 | Effect of hyperkalemia on myocardial depression by verapamil in isolated hearts. ( Boyd, SG; Jolly, SR; Mehta, P; Movahed, A; Reeves, WC; Wilson, VP, 1993) |
| " Common factors were hyperkalemia and verapamil therapy." | 3.68 | Effect of hyperkalemia on experimental myocardial depression by verapamil. ( Jolly, SR; Keaton, N; Movahed, A; Reeves, WC; Rose, GC, 1991) |
| " Using ECG evidence for severe hyperkalemia, the halothane-anesthetized dogs were rendered acutely hyperkalemic to similar plasma levels of K+ (K+ = 8." | 3.67 | Verapamil worsens rate of development and hemodynamic effects of acute hyperkalemia in halothane-anesthetized dogs: effects of calcium therapy. ( Moyer, TP; Nugent, M; Tinker, JH, 1984) |
| "In vitro prospective, repeated-measures, dose-response study." | 1.29 | Effect of calcium to reverse the electrocardiographic effects of hyperkalemia in the isolated rat heart: a prospective, dose-response study. ( Bisogno, JL; Langley, A; Von Dreele, MM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (40.00) | 18.7374 |
| 1990's | 10 (50.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hegazi, MO | 1 |
| Aldabie, G | 1 |
| Al-Mutairi, S | 1 |
| El Sayed, A | 1 |
| Letavernier, E | 1 |
| Couzi, L | 1 |
| Delmas, Y | 1 |
| Moreau, K | 1 |
| Murcott, O | 1 |
| de Précigout, V | 1 |
| Nugent, M | 1 |
| Tinker, JH | 1 |
| Moyer, TP | 1 |
| Saltzman, LS | 1 |
| Kates, RA | 1 |
| Corke, BC | 1 |
| Norfleet, EA | 1 |
| Heath, KR | 1 |
| Waeber, B | 1 |
| Brunner, HR | 1 |
| Gilmour, RF | 1 |
| Zipes, DP | 1 |
| O'Neill, M | 1 |
| Ryan, DM | 1 |
| Paterson, DJ | 1 |
| Patel, R | 1 |
| Lipper, B | 1 |
| Schwartzbard, A | 1 |
| Nelson, C | 1 |
| O'Connor, MA | 1 |
| Frishman, W | 1 |
| Bisogno, JL | 1 |
| Langley, A | 1 |
| Von Dreele, MM | 1 |
| Jolly, SR | 2 |
| Wilson, VP | 1 |
| Movahed, A | 2 |
| Mehta, P | 1 |
| Boyd, SG | 1 |
| Reeves, WC | 2 |
| Schmidt, C | 1 |
| Schwendenwein, I | 1 |
| Wieselthaler, G | 1 |
| Roschal, K | 1 |
| Schima, H | 1 |
| Losert, U | 1 |
| Wolner, E | 1 |
| Tang, T | 2 |
| Duffield, R | 2 |
| Ho, AK | 2 |
| Dong, C | 1 |
| Pacini, DJ | 1 |
| Boachie-Ansah, G | 1 |
| Kane, KA | 1 |
| Reverte, M | 1 |
| García-Barrado, MJ | 1 |
| Moratinos, J | 1 |
| Keaton, N | 1 |
| Rose, GC | 1 |
| San Juan, AC | 1 |
| Wong, KC | 1 |
| Port, JD | 1 |
| Rubin, AS | 1 |
| Zablocki, AD | 1 |
| Reddy, GV | 1 |
| Schamroth, L | 1 |
| Schamroth, CL | 1 |
| Bender, F | 1 |
| Reploh, HD | 1 |
1 review available for verapamil and Hyperkalemia
| Article | Year |
|---|---|
[New therapeutic approaches to arterial hypertension].
Topics: Angiotensin II; Benzothiadiazines; Calcium; Calcium Channel Blockers; Captopril; Diuretics; Drug The | 1982 |
19 other studies available for verapamil and Hyperkalemia
| Article | Year |
|---|---|
Junctional bradycardia with verapamil in renal failure--care required even with mild hyperkalaemia.
Topics: Aged; Bradycardia; Calcium Channel Blockers; Delayed-Action Preparations; Female; Humans; Hyperkalem | 2012 |
Verapamil and mild hyperkalemia in hemodialysis patients: a potentially hazardous association.
Topics: Blood Chemical Analysis; Follow-Up Studies; Heart Block; Humans; Hyperkalemia; Kidney Failure, Chron | 2006 |
Verapamil worsens rate of development and hemodynamic effects of acute hyperkalemia in halothane-anesthetized dogs: effects of calcium therapy.
Topics: Acute Disease; Anesthesia, Inhalation; Animals; Blood Pressure; Calcium; Carbon Dioxide; Cardiac Out | 1984 |
Hyperkalemia and cardiovascular collapse after verapamil and dantrolene administration in swine.
Topics: Animals; Dantrolene; Drug Evaluation, Preclinical; Drug Interactions; Electric Stimulation; Heart Ar | 1984 |
Different electrophysiological responses of canine endocardium and epicardium to combined hyperkalemia, hypoxia, and acidosis.
Topics: Acidosis; Action Potentials; Animals; Dogs; Electrophysiology; Endocardium; Hyperkalemia; Hypoxia; M | 1980 |
Effect of verapamil on restoration of cardiac performance in raised [K+]o by adrenergic stimulation in the rabbit.
Topics: Action Potentials; Animals; Blood Gas Analysis; Cardiotonic Agents; Female; Hydrogen-Ion Concentrati | 1995 |
Toxic effects of diltiazem in a patient with chronic renal failure.
Topics: Acidosis; Adult; Diltiazem; Heart Failure; Humans; Hyperkalemia; Hypotension; Kidney Failure, Chroni | 1994 |
Effect of calcium to reverse the electrocardiographic effects of hyperkalemia in the isolated rat heart: a prospective, dose-response study.
Topics: Animals; Calcimycin; Calcium; Dose-Response Relationship, Drug; Electrocardiography; Heart; Heart Ra | 1994 |
Effect of hyperkalemia on myocardial depression by verapamil in isolated hearts.
Topics: Animals; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hea | 1993 |
Pharmacologically induced heart failure for the evaluation of circulatory assistance.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Cattle; | 1996 |
Effects of Ca2+ channel blockers on Ca2+ loading induced by metabolic inhibition and hyperkalemia in cardiomyocytes.
Topics: Animals; Benzimidazoles; Calcium; Calcium Channel Blockers; Cells, Cultured; Chickens; Cyanides; Hyp | 1998 |
Protection of cardiomyocytes by pinacidil during metabolic inhibition and hyperkalemia.
Topics: Adenosine Triphosphate; Animals; Bepridil; Calcium; Calcium Channel Blockers; Cells, Cultured; Chick | 1999 |
Modification by hypoxia, hyperkalaemia and acidosis of the cardiac electrophysiological effects of a range of antiarrhythmic drugs.
Topics: Acidosis; Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Ele | 1992 |
Role of alpha-adrenoceptors in control of plasma potassium in conscious rabbits.
Topics: Animals; Apamin; Calcium Channels; Clonidine; Dioxanes; Ethanolamines; Hyperkalemia; Idazoxan; Potas | 1991 |
Effect of hyperkalemia on experimental myocardial depression by verapamil.
Topics: Acute Disease; Animals; Bradycardia; Calcium; Depression, Chemical; Disease Models, Animal; Dogs; Dr | 1991 |
Hyperkalemia after dantrolene and verapamil-dantrolene administration in dogs.
Topics: Animals; Blood Pressure; Calcium; Cardiac Output; Dantrolene; Dogs; Drug Interactions; Heart Rate; H | 1988 |
Hyperkalemia, verapamil, and dantrolene.
Topics: Colectomy; Colonic Neoplasms; Coronary Disease; Dantrolene; Drug Interactions; Humans; Hyperkalemia; | 1987 |
Tall and peaked U waves in hypokalemia.
Topics: Adult; Aged; Alcoholic Intoxication; Diagnosis, Differential; Electrocardiography; Humans; Hyperkale | 1987 |
[Management of ventricular tachycardias using Isoptin].
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; Hyperkalemia; Inject | 1968 |