verapamil has been researched along with Hyperinsulinism in 8 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "we observe the efficacy of verapamil and amlodipine administered simultaneously in the medical treatment of endogenous hyperinsulinemic hypoglycemia." | 7.73 | [Successful pharmacological treatment of hyperinsulinemic hypoglycemia with verapamil and amlodipine--case report]. ( Owecki, M; Sowiński, J, 2005) |
| " Forearm blood flow responses to graded doses of acetylcholine, sodium nitroprusside, and verapamil were assessed by strain-gauge plethysmography in patients with obesity-related MetS (n = 20) and in matched controls (n = 18) before and after intra-arterial infusion of insulin (0." | 3.76 | Generalized impairment of vasodilator reactivity during hyperinsulinemia in patients with obesity-related metabolic syndrome. ( Cardillo, C; Galli, A; Lauro, D; Mores, N; Porzio, O; Rovella, V; Schinzari, F; Tesauro, M, 2010) |
| "we observe the efficacy of verapamil and amlodipine administered simultaneously in the medical treatment of endogenous hyperinsulinemic hypoglycemia." | 3.73 | [Successful pharmacological treatment of hyperinsulinemic hypoglycemia with verapamil and amlodipine--case report]. ( Owecki, M; Sowiński, J, 2005) |
| "The 2 patients with recurrences are now successfully treated with a calcium channel blocker, an approach, to our knowledge, never before reported for adult-onset nesidioblastosis." | 2.41 | Adult-onset nesidioblastosis causing hypoglycemia: an important clinical entity and continuing treatment dilemma. ( Costa, EA; Kaplan, EL; Koka, MR; Straus II, FH; Sugg, SL; Witteles, RM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schinzari, F | 1 |
| Tesauro, M | 1 |
| Rovella, V | 1 |
| Galli, A | 1 |
| Mores, N | 1 |
| Porzio, O | 1 |
| Lauro, D | 1 |
| Cardillo, C | 1 |
| Owecki, M | 1 |
| Sowiński, J | 1 |
| Patel, NP | 2 |
| Pugh, ME | 2 |
| Goldberg, S | 2 |
| Eiger, G | 2 |
| Lehmann, HU | 1 |
| Hochrein, H | 1 |
| Kane, C | 1 |
| Shepherd, RM | 1 |
| Squires, PE | 1 |
| Johnson, PR | 1 |
| James, RF | 1 |
| Milla, PJ | 1 |
| Aynsley-Green, A | 1 |
| Lindley, KJ | 1 |
| Dunne, MJ | 1 |
| Witteles, RM | 1 |
| Straus II, FH | 1 |
| Sugg, SL | 1 |
| Koka, MR | 1 |
| Costa, EA | 1 |
| Kaplan, EL | 1 |
| Draznin, B | 1 |
| Sussman, KE | 1 |
| Eckel, RH | 1 |
| Kao, M | 1 |
| Yost, T | 1 |
| Sherman, NA | 1 |
3 reviews available for verapamil and Hyperinsulinism
| Article | Year |
|---|---|
Hyperinsulinemic euglycemia therapy for verapamil poisoning: a review.
Topics: Animals; Antidotes; Critical Care; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; United Sta | 2007 |
[Indications for use of calcium antagonists].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Coronary Disease | 1980 |
Adult-onset nesidioblastosis causing hypoglycemia: an important clinical entity and continuing treatment dilemma.
Topics: Adult; Age of Onset; Calcium Channel Blockers; Combined Modality Therapy; Diabetes Mellitus, Type 1; | 2001 |
5 other studies available for verapamil and Hyperinsulinism
| Article | Year |
|---|---|
Generalized impairment of vasodilator reactivity during hyperinsulinemia in patients with obesity-related metabolic syndrome.
Topics: Acetylcholine; Analysis of Variance; Ascorbic Acid; Chromatography, High Pressure Liquid; Dose-Respo | 2010 |
[Successful pharmacological treatment of hyperinsulinemic hypoglycemia with verapamil and amlodipine--case report].
Topics: Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Female; Humans; Hyperinsulinism; Hypertensi | 2005 |
Hyperinsulinemic euglycemia therapy for verapamil poisoning: case report.
Topics: Antidotes; Captopril; Critical Care; Drug Combinations; Female; Glyburide; Humans; Hyperinsulinism; | 2007 |
Loss of functional KATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy.
Topics: Action Potentials; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Calcium Channel Blocke | 1996 |
Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemia.
Topics: Adipose Tissue; Adult; Biopsy; Calcium; Cytosol; Deoxyglucose; Female; Glyburide; Humans; Hyperinsul | 1988 |