Page last updated: 2024-10-24

verapamil and Hyperemia

verapamil has been researched along with Hyperemia in 10 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).

Research Excerpts

ExcerptRelevanceReference
" The bi-fluorophenyl-piperazine derivatives, lidoflazine and flunarizine, enhanced the reactive hyperemia elicited by a brief (30 s) anoxic challenge."7.67The effects of lidoflazine and flunarizine on cerebral reactive hyperemia. ( DeLong, RE; Phillis, JW; Towner, JK, 1985)
"A 20-year-old female with hemiplegic migraine was treated during an acute attack with intravenous verapamil, which reproducibly resolved the headache within 20 min but did not affect her hemiplegia."3.74Hemiplegic migraine: hyperperfusion and abortive therapy with intravenous verapamil. ( Dulli, DA; Hsu, DA; Kiff, JE; Rowley, HA; Stafstrom, CE, 2008)
" The bi-fluorophenyl-piperazine derivatives, lidoflazine and flunarizine, enhanced the reactive hyperemia elicited by a brief (30 s) anoxic challenge."3.67The effects of lidoflazine and flunarizine on cerebral reactive hyperemia. ( DeLong, RE; Phillis, JW; Towner, JK, 1985)
"The influence of an increased Ca concentration on reactive hyperemia, work induced vasodilation and pharmacologically induced dilation (adenosine, nifedipine, verapamil) was studied in the blood perfused gastrocnemius of dogs."3.65[The effect of increased extracellular calcium concentration on the hypoxic and pharmacologic hyperemia of skeletal muscle]. ( Marten, W; Meyer, VU; Raff, WK; Schiffer, W, 1975)
"Pretreatment with verapamil markedly improved survival of skin flaps after 6 hours of venous cross-clamping compared with animals receiving placebo only (99% vs 53."1.28Verapamil improves survival of rat hyperemic island skin flaps. ( Fayman, MS; Hinder, RA; Oosthuizen, MM; Stein, HJ, 1989)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Teplyi, V1
Grebchenko, K1
Hsu, DA1
Stafstrom, CE1
Rowley, HA1
Kiff, JE1
Dulli, DA1
Koller, A1
Rubányi, G1
Ligeti, L1
Kovách, AG2
Meyer, VU1
Marten, W1
Schiffer, W1
Raff, WK1
Yoshikawa, T1
Akaishi, M1
Ikeda, F1
Handa, S1
Nakamura, Y1
Urbanics, R1
Stein, HJ1
Fayman, MS1
Oosthuizen, MM1
Hinder, RA1
Kimura, T1
Satoh, S1
Phillis, JW1
DeLong, RE1
Towner, JK1
Winbury, MM1
Howe, BB1
Hefner, MA1

Trials

1 trial available for verapamil and Hyperemia

ArticleYear
THE USAGE OF RADIOFREQUENCY ABLATION FOR TREATMENT OF KELOIDS AND HYPERTROPHIC SCARS.
    Problemy radiatsiinoi medytsyny ta radiobiolohii, 2019, Volume: 24

    Topics: Adult; Catheter Ablation; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Fluorouracil; H

2019

Other Studies

9 other studies available for verapamil and Hyperemia

ArticleYear
Hemiplegic migraine: hyperperfusion and abortive therapy with intravenous verapamil.
    Brain & development, 2008, Volume: 30, Issue:1

    Topics: Adult; Brain; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Cerebrovascular

2008
Inhibition of myocardial reactive hyperaemia but not of hypoxic coronary vasodilatation by constant verapamil infusion in the in situ dog heart.
    Acta physiologica Academiae Scientiarum Hungaricae, 1982, Volume: 59, Issue:2

    Topics: Animals; Arterial Occlusive Diseases; Blood Flow Velocity; Coronary Circulation; Depression, Chemica

1982
[The effect of increased extracellular calcium concentration on the hypoxic and pharmacologic hyperemia of skeletal muscle].
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:5

    Topics: Adenosine; Animals; Calcium; Dogs; Hyperemia; Hypoxia; Muscles; Nifedipine; Regional Blood Flow; Sti

1975
Mechanisms of transient augmentation of myocardial contraction after a brief coronary occlusion.
    Japanese circulation journal, 1992, Volume: 56, Issue:4

    Topics: Animals; Calcium; Catecholamines; Constriction; Coronary Circulation; Coronary Disease; Dogs; Hemody

1992
Effect of emopamil on cerebrocortical microcirculation during hypoxia and reactive hyperemia and on [K+]e, pH, pO2 changes during and after N2 anoxia.
    Advances in experimental medicine and biology, 1989, Volume: 248

    Topics: Animals; Calcium Channel Blockers; Cats; Cerebral Cortex; Hydrogen-Ion Concentration; Hyperemia; Hyp

1989
Verapamil improves survival of rat hyperemic island skin flaps.
    Surgery, 1989, Volume: 106, Issue:4

    Topics: Animals; Constriction; Free Radicals; Glutathione; Graft Survival; Hyperemia; Ischemia; Lipid Peroxi

1989
Inhibitory effect of quinacrine on myocardial reactive hyperemia in the dog.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Acetylcholine; Adenosine; Animals; Blood Flow Velocity; Catechols; Coronary Circulation; Dogs; Femal

1985
The effects of lidoflazine and flunarizine on cerebral reactive hyperemia.
    European journal of pharmacology, 1985, Jun-19, Volume: 112, Issue:3

    Topics: Animals; Blood Gas Analysis; Cerebrovascular Circulation; Cinnarizine; Extracorporeal Circulation; F

1985
Effect of nitrates and other coronary dilators on large and small coronary vessels: an hypothesis for the mechanism of action of nitrates.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1

    Topics: Aminophylline; Animals; Aorta; Biophysical Phenomena; Biophysics; Blood Circulation; Blood Flow Velo

1969