Page last updated: 2024-10-24

verapamil and Hemorrhagic Shock

verapamil has been researched along with Hemorrhagic Shock in 13 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"Myocardial blood flow and left ventricular oxygen utilization were studied in verapamil-treated and untreated pentobarbital-anesthetized dogs subjected to hemorrhagic shock."7.66Effects of verapamil on heart and circulation in hemorrhagic shock in dogs. ( Hackel, DB; Mikat, EM; Reimer, K; Whalen, G, 1981)
"Verapamil treatment immediately after the hemorrhage (group 3, N = 4) increased the survival rate to 75% (three of four animals)."5.28Verapamil treatment of canine hemorrhagic shock. ( Allison, EJ; Carroll, RG; Farmer, PL; Iams, SG; Pryor, WH, 1989)
"Dogs were subjected to a standardized hemorrhagic shock procedure."5.26Treatment of hemorrhagic shock in dogs with verapamil: effects on survival and on cardiovascular lesions. ( Hackel, DB; Mikat, EM; Reimer, K; Rochlani, SP; Whalen, G, 1979)
"Cardiogenic shock is associated with primary myocardial failure and a low-flow state."2.36Calcium entry blockers: potential applications in shock. ( Greenfield, LJ; Hess, ML, 1983)
"Acute renal failure following hemorrhagic shock was studied in awake rats."1.28Acute renal failure following hemorrhagic shock: protective and aggravating factors. ( Rocha, AS; Seguro, AC; Yu, L, 1992)
"Dogs were subjected to a standardized hemorrhagic shock procedure."1.26Treatment of hemorrhagic shock in dogs with verapamil: effects on survival and on cardiovascular lesions. ( Hackel, DB; Mikat, EM; Reimer, K; Rochlani, SP; Whalen, G, 1979)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhao, KS1
Jin, C1
Huang, X1
Liu, J1
Yan, WS1
Huang, Q1
Kan, W1
Hess, ML3
Warner, MF1
Smith, JM1
Manson, NH1
Greenfield, LJ3
Mahany, TM1
Whalen, GF1
Hackel, DB3
Mikat, E1
Mikat, EM2
Reimer, K2
Whalen, G2
Rochlani, SP1
Yu, L1
Seguro, AC1
Rocha, AS1
Horton, JW1
Carroll, RG1
Iams, SG1
Farmer, PL1
Pryor, WH1
Allison, EJ1
Pollard, BJ1
Fletcher, IR1
Tait, AR1
Knight, PR1
Van der Spek, AF1
Leahy, AL1
Galla, J1
Fitzpatrick, JM1
Wait, RB1
Wang, SG1
Meng, XJ1
Huang, ZQ1

Reviews

2 reviews available for verapamil and Hemorrhagic Shock

ArticleYear
Calcium channel blockers in shock.
    Progress in clinical and biological research, 1983, Volume: 111

    Topics: Calcium Channel Blockers; Cardiovascular System; Hemodynamics; Humans; Ischemia; Shock; Shock, Hemor

1983
Calcium entry blockers: potential applications in shock.
    Advances in shock research, 1983, Volume: 10

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Diltiazem; Dogs

1983

Other Studies

11 other studies available for verapamil and Hemorrhagic Shock

ArticleYear
The mechanism of Polydatin in shock treatment.
    Clinical hemorheology and microcirculation, 2003, Volume: 29, Issue:3-4

    Topics: Animals; Calcium Channel Blockers; Calcium Signaling; Cell Adhesion; Cells, Cultured; Drug Evaluatio

2003
Improved myocardial hemodynamic and cellular function with calcium channel blockade (verapamil) during canine hemorrhagic shock.
    Circulatory shock, 1983, Volume: 10, Issue:2

    Topics: Animals; Blood Gas Analysis; Calcium; Calcium Channel Blockers; Dogs; Female; Hemodynamics; Infusion

1983
Prevention of portal hypertension and small bowel hemorrhage in dogs treated with verapamil during hemorrhagic shock.
    Circulatory shock, 1980, Volume: 7, Issue:4

    Topics: Animals; Blood Pressure; Dogs; Gastrointestinal Hemorrhage; Hypertension, Portal; Intestine, Small;

1980
Effects of verapamil on heart and circulation in hemorrhagic shock in dogs.
    The American journal of physiology, 1981, Volume: 241, Issue:1

    Topics: Animals; Blood Pressure; Dogs; Heart; Heart Rate; Heart Ventricles; Male; Oxygen; Oxygen Consumption

1981
Treatment of hemorrhagic shock in dogs with verapamil: effects on survival and on cardiovascular lesions.
    Laboratory investigation; a journal of technical methods and pathology, 1979, Volume: 41, Issue:4

    Topics: Animals; Dogs; Gastrointestinal Hemorrhage; Heart; Heart Rate; Intestines; Male; Myocardium; Shock,

1979
Acute renal failure following hemorrhagic shock: protective and aggravating factors.
    Renal failure, 1992, Volume: 14, Issue:1

    Topics: Acute Kidney Injury; Allopurinol; Animals; Calcium; Dehydration; Free Radicals; Gentamicins; Kidney;

1992
Calcium-channel blockade in canine hemorrhagic shock.
    The American journal of physiology, 1989, Volume: 257, Issue:5 Pt 2

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Dogs; Electrolytes; Hemodynamics; Membrane

1989
Verapamil treatment of canine hemorrhagic shock.
    Annals of emergency medicine, 1989, Volume: 18, Issue:7

    Topics: Animals; Blood Pressure; Dogs; Heart Rate; Hematocrit; Male; Shock, Hemorrhagic; Verapamil

1989
The effects of calcium-blocking agents on sympathetic responses to acute haemorrhagic shock in dogs.
    European journal of anaesthesiology, 1987, Volume: 4, Issue:5

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Dogs; Female; Hemodynamics; Male; Nifedipine; Renin; S

1987
The canine kidney in haemorrhagic shock: effect of verapamil.
    European urology, 1987, Volume: 13, Issue:6

    Topics: Animals; Dogs; Female; Heart Block; Hemodynamics; Kidney; Renal Circulation; Shock, Hemorrhagic; Ver

1987
[Protective effect of a calcium channel blocker on cellular function in hypoperfusion].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1987, Volume: 25, Issue:11

    Topics: Animals; Male; Multiple Organ Failure; Rats; Rats, Inbred Strains; Shock, Hemorrhagic; Verapamil

1987