Page last updated: 2024-10-24

verapamil and Hemolysis

verapamil has been researched along with Hemolysis in 11 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
" The nasal bioavailability of nicardipine from plain buffered solution was 44%, and increased steadily to 56-79% in direct proportion to the amount of PEG 400 added."1.30Evaluation of the effect of polyethylene glycol 400 on the nasal absorption of nicardipine and verapamil in the rat. ( Lau-Cam, CA; Rahman, M, 1999)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deng, X1
Qiu, Q1
Yang, B1
Wang, X1
Huang, W1
Qian, H1
Wang, T1
Wen, XJ1
Mei, XB1
Wang, QQ1
He, Q1
Zheng, JM1
Zhao, J1
Xiao, L1
Zhang, LM1
Bailey, PM1
Bakker, AJ1
Seymour, JE1
Wilce, JA1
Watts, TJ1
Handy, RD1
GutiƩrrez, JM1
Ownby, CL1
Odell, GV1
Binah, O1
Berke, G1
Rosen, D1
Hoffman, BF1
Sugimoto, N1
Haque, A1
Horiguchi, Y1
Matsuda, M1
Rahman, M1
Lau-Cam, CA1
Teng, CM1
Lee, LG1
Lee, CY1
Ferlan, I1
Falconer, IR1
Runnegar, MT1
Robak, J1
Duniec, Z1

Other Studies

11 other studies available for verapamil and Hemolysis

ArticleYear
Design, synthesis and biological evaluation of novel peptides with anti-cancer and drug resistance-reversing activities.
    European journal of medicinal chemistry, 2015, Jan-07, Volume: 89

    Topics: Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug;

2015
Lipid peroxidation is another potential mechanism besides pore-formation underlying hemolysis of tentacle extract from the jellyfish Cyanea capillata.
    Marine drugs, 2013, Jan-09, Volume: 11, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Calcium; Calcium Channel Blockers; Cnidarian Venoms; Diltiazem

2013
A functional comparison of the venom of three Australian jellyfish--Chironex fleckeri, Chiropsalmus sp., and Carybdea xaymacana--on cytosolic Ca2+, haemolysis and Artemia sp. lethality.
    Toxicon : official journal of the International Society on Toxinology, 2005, Volume: 45, Issue:2

    Topics: Animals; Artemia; Calcium; Calcium Channel Blockers; Cnidarian Venoms; Cubozoa; Erythrocytes; Hemoly

2005
The haemolytic effect of verapamil on erythrocytes exposed to varying osmolarity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:5

    Topics: Animals; Calcium; Calcium Channel Blockers; Chelating Agents; Dose-Response Relationship, Drug; Egta

2007
Isolation of a myotoxin from Bothrops asper venom: partial characterization and action on skeletal muscle.
    Toxicon : official journal of the International Society on Toxinology, 1984, Volume: 22, Issue:1

    Topics: Animals; Calcium; Crotalid Venoms; Hemolysis; Hemorrhage; Hydrolysis; Immunodiffusion; Mice; Molecul

1984
Calcium channel blockers modify electrophysiological effects induced by lytic granules from cytotoxic T lymphocytes in guinea pig ventricular myocytes.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Action Potentials; Animals; Cadmium; Cadmium Chloride; Calcium Channel Blockers; Chlorides; Cobalt;

1994
Coronary vasoconstriction is the most probable cause of death of rats intoxicated with botulinolysin, a hemolysin produced by Clostridium botulinum.
    Toxicon : official journal of the International Society on Toxinology, 1995, Volume: 33, Issue:9

    Topics: Animals; Aspirin; Blood Pressure; Botulinum Toxins; Botulism; Clostridium botulinum; Electrocardiogr

1995
Evaluation of the effect of polyethylene glycol 400 on the nasal absorption of nicardipine and verapamil in the rat.
    Die Pharmazie, 1999, Volume: 54, Issue:2

    Topics: Administration, Intranasal; Adsorption; Algorithms; Animals; Calcium Channel Blockers; Excipients; H

1999
Platelet aggregation induced by equinatoxin.
    Thrombosis research, 1988, Dec-01, Volume: 52, Issue:5

    Topics: Adenosine Triphosphate; Animals; Blood Platelets; Calcium; Cnidarian Venoms; Hemolysis; In Vitro Tec

1988
Effects of the peptide toxin from Microcystis aeruginosa on intracellular calcium, pH and membrane integrity in mammalian cells.
    Chemico-biological interactions, 1987, Volume: 63, Issue:3

    Topics: Animals; Calcium; Cell Membrane Permeability; Cells; Hemolysis; Humans; Hydrogen-Ion Concentration;

1987
Membrane activity, antioxidant, antiaggregatory and antihemolytic properties of four calcium channel blockers.
    Pharmacological research communications, 1986, Volume: 18, Issue:12

    Topics: Animals; Antioxidants; Blood Platelets; Calcium Channel Blockers; Cell Membrane; Diltiazem; Erythroc

1986