Page last updated: 2024-10-24

verapamil and Heart Valve Diseases

verapamil has been researched along with Heart Valve Diseases in 11 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).

Research Excerpts

ExcerptRelevanceReference
"The authors have investigated the haemodynamic effects of verapamil on the pulmonary circulation by 24 patients suffering from secondary pulmonary hypertension, caused by mitral and/or aortic valve diseases."7.67[Hemodynamic effects of verapamil in pulmonary hypertension caused by heart valve disease]. ( Kelemen, S; Marozsán, I; Szatmáry, L, 1989)
"Verapamil was administered intravenously to 250 patients aged between 14 and 85, suffering from tachyarrhythmia of various type."7.65[Clinical results with verapamil in intravenous administration in the emergency therapy of cardiac arrhythmias]. ( Amoroso, A, 1975)
"The authors have investigated the haemodynamic effects of verapamil on the pulmonary circulation by 24 patients suffering from secondary pulmonary hypertension, caused by mitral and/or aortic valve diseases."3.67[Hemodynamic effects of verapamil in pulmonary hypertension caused by heart valve disease]. ( Kelemen, S; Marozsán, I; Szatmáry, L, 1989)
"Verapamil was administered intravenously to 250 patients aged between 14 and 85, suffering from tachyarrhythmia of various type."3.65[Clinical results with verapamil in intravenous administration in the emergency therapy of cardiac arrhythmias]. ( Amoroso, A, 1975)
" We build upon our previous findings and generated a simple index for the adequate administration dosage of beta-methyldigoxin based on variable degrees of renal function and the serum trough level of beta-methyldigoxin."2.44[Pharmaceutical support in the cardiovascular and cardiovascular surgery ward]. ( Kataoka, Y; Machida, S; Masuda, K, 2007)
"The management of arrhythmias during pregnancy is, in principle, similar to that in nonpregnant patients, however, special consideration must be given, to avoid adverse fetal effects."1.31[Treatment of cardiac arrhythmia in pregnant women]. ( Halawa, B, 2000)
"In the 12 patients with mitral insufficiency, verapamil resulted in a 19% increase in both cardiac index (p = 0."1.27Hemodynamic effects of verapamil in left ventricular valvular volume overload. ( Butman, SM; Eagan, J; Olson, HG, 1985)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scherer, M1
Dzemali, O1
Aybek, T1
Wimmer-Greinecker, G1
Moritz, A1
Machida, S1
Masuda, K1
Kataoka, Y1
Marsocci, G1
Boschetti, C1
Manai, L1
Sica, G1
Loscudo, L1
Halawa, B1
Singh, BN1
Roche, AH1
Amoroso, A1
Marozsán, I1
Szatmáry, L1
Kelemen, S1
Butman, SM1
Eagan, J1
Olson, HG1
Padrini, R1
Barbieri, E1
Piovan, D1
Toffoli, M1
Motta, A1
Trevi, GP1
Ferrari, M1
Goto, N1
Storstein, O1
Rasmussen, K1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Automated External Defibrillator (AED) Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named One Shock Per Minute"[NCT00139542]Phase 35,107 participants (Actual)Interventional2005-09-30Completed
Comparism Between Efficacy and Effectiveness Between Slow Infusion of Calcium Channel Blockers and Intravenous Bolus Adenosine in the Management of Supraventricular Tachycardia in the Emergency Department.[NCT00413712]Phase 4206 participants Interventional1997-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for verapamil and Heart Valve Diseases

ArticleYear
[Pharmaceutical support in the cardiovascular and cardiovascular surgery ward].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2007, Volume: 127, Issue:11

    Topics: Aged; Anti-Bacterial Agents; Cardiology Service, Hospital; Cefazolin; Coronary Artery Bypass, Off-Pu

2007

Trials

1 trial available for verapamil and Heart Valve Diseases

ArticleYear
Effects of intravenous verapamil on hemodynamics in patients with heart disease.
    American heart journal, 1977, Volume: 94, Issue:5

    Topics: Adult; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Coronary Disease; Depression, Chemi

1977

Other Studies

9 other studies available for verapamil and Heart Valve Diseases

ArticleYear
Impact of left atrial size reduction on chronic atrial fibrillation in mitral valve surgery.
    The Journal of heart valve disease, 2003, Volume: 12, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pac

2003
[Myocardial damage caused by ischemia and/or re-perfusion in cardiac surgery: prevention and treatment with verapamil].
    Bollettino della Societa italiana di cardiologia, 1981, Volume: 26, Issue:12

    Topics: Adult; Cardiac Output, Low; Cardiac Surgical Procedures; Coronary Artery Bypass; Coronary Disease; F

1981
[Treatment of cardiac arrhythmia in pregnant women].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2000, Volume: 9, Issue:50

    Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Arrhythmias, Cardiac; Digoxin; Electric Countershock;

2000
[Clinical results with verapamil in intravenous administration in the emergency therapy of cardiac arrhythmias].
    Minerva medica, 1975, May-26, Volume: 66, Issue:39

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Coronary Disease; Female; Heart

1975
[Hemodynamic effects of verapamil in pulmonary hypertension caused by heart valve disease].
    Orvosi hetilap, 1989, Apr-30, Volume: 130, Issue:18

    Topics: Adult; Blood Pressure; Female; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Male; Middle A

1989
Hemodynamic effects of verapamil in left ventricular valvular volume overload.
    American heart journal, 1985, Volume: 110, Issue:2

    Topics: Aortic Valve Insufficiency; Blood Pressure; Cardiac Catheterization; Diastole; Heart Valve Diseases;

1985
Plasma levels and myocardial content of verapamil, norverapamil and two N-dealkyl-metabolites in man.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:6

    Topics: Adult; Aged; Chromatography, High Pressure Liquid; Coronary Disease; Female; Heart Valve Diseases; H

1985
[Clinical pathophysiological studies on the effects of various coronary vasodilators on myocardial carbohydrate metabolism. 2. Effects of various coronary vasodilators on myocardial carbohydrate metabolism in various diseases].
    Japanese circulation journal, 1972, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Aged; Benzoates; Benzofurans; Blood Glucose; Carbohydrate Metabolism; Coronary Di

1972
Digitalis and atrial tachycardia with block.
    British heart journal, 1974, Volume: 36, Issue:2

    Topics: Adult; Aged; Coronary Disease; Digitoxin; Electric Countershock; Electrocardiography; Female; Heart

1974