Page last updated: 2024-10-24

verapamil and Heart Defects, Congenital

verapamil has been researched along with Heart Defects, Congenital in 19 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.

Research Excerpts

ExcerptRelevanceReference
"Verapamil was administered intravenously to 250 patients aged between 14 and 85, suffering from tachyarrhythmia of various type."7.65[Clinical results with verapamil in intravenous administration in the emergency therapy of cardiac arrhythmias]. ( Amoroso, A, 1975)
"Verapamil was administered intravenously to 250 patients aged between 14 and 85, suffering from tachyarrhythmia of various type."3.65[Clinical results with verapamil in intravenous administration in the emergency therapy of cardiac arrhythmias]. ( Amoroso, A, 1975)
"Twenty-five VTs showed right bundle branch block morphology and 23 left bundle branch block morphology, and VT was entrained in 84 and 96%, respectively."1.29Frequency of presumed reentry with an excitable gap in sustained ventricular tachycardia unassociated with coronary artery disease. ( Aizawa, Y; Kitazawa, H; Kusano, Y; Naitoh, N; Shibata, A; Uchiyama, H; Washizuka, T, 1993)
"Verapamil was used in one infant with AV node reentry tachycardia."1.29Efficacy and risks of medical therapy for supraventricular tachycardia in neonates and infants. ( Saul, JP; Walsh, EP; Weindling, SN, 1996)
"Supraventricular tachycardia is one of the most frequent arrhythmias in childhood."1.27[Supraventricular tachycardia in children]. ( Attanà, A; Battaglia, T; Caristo, S; Ciconte, V; Fumarulo, A; Martini, B; Paparo, F, 1983)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's5 (26.32)18.2507
2000's1 (5.26)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tang, C1
Luo, C1
Hua, Y1
Zhou, K1
Duan, H1
Ma, F1
Zhang, Y1
Li, Y1
Qiu, D1
Wang, C1
Kazanskaia, GM1
Volkov, AM1
D'iakonitsa, TM1
Zhdanov, GP1
Gracián Gómez, M1
Rodríguez Caamaño, J1
Guía Torrent, JM1
Battaglia, T1
Paparo, F1
Fumarulo, A1
Attanà, A1
Ciconte, V1
Caristo, S1
Martini, B1
Leitner, RP1
Hawker, RE1
Celermajer, JM1
Aizawa, Y1
Naitoh, N1
Kitazawa, H1
Kusano, Y1
Uchiyama, H1
Washizuka, T1
Shibata, A1
Weindling, SN1
Saul, JP1
Walsh, EP1
Gabbarini, F1
Amino, JG1
Studart, PC1
de Brito, AH1
Brando, PR1
Maia, IG1
Almeida, G1
Dohmann, HJ1
Amoroso, A1
Binder, LS1
Boeche, R1
Atkinson, D1
Jaffee, OC1
Jaffee, AL1
Takagi, Y1
Bruyere, HJ2
Nishikawa, T2
Kajita, A1
Ando, M1
Takao, A1
Gilbert, EF1
Bolens, M1
Friedli, B1
Deom, A1
Hirsch, IA1
Zauder, HL1
Barousch, R1
Storstein, O1
Rasmussen, K1
Rudolph, W1
Kriener, J1
Meister, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intranasal Dexmedetomidine vs Oral Triclofos Sodium Sedation for Children With Autism Undergoing Electroencephalograms - A Randomized Controlled Trial.[NCT04270708]Phase 4200 participants (Anticipated)Interventional2020-03-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for verapamil and Heart Defects, Congenital

ArticleYear
[Recent advances and future perspectives in the medical treatment of cardiopathies in children].
    Revista espanola de cardiologia, 1984, Volume: 37 Suppl 1

    Topics: Child; Ductus Arteriosus, Patent; Heart Defects, Congenital; Heart Failure; Humans; Hypoxia; Indomet

1984

Other Studies

18 other studies available for verapamil and Heart Defects, Congenital

ArticleYear
Placental P-glycoprotein inhibition enhances susceptibility to Di-(2-ethylhexyl)-phthalate induced cardiac malformations in mice: A possibly promising target for congenital heart defects prevention.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Diethylhexyl Phthalate; Female; Fe

2019
[Endothelium of myocardium microvessel under conditions of hypothermia, ischemia, reperfusion and pharmaco-cold cardioplegia with calcium antagonist].
    Tsitologiia, 2005, Volume: 47, Issue:1

    Topics: Calcium Channel Blockers; Cardioplegic Solutions; Coronary Vessels; Endothelium, Vascular; Heart Atr

2005
[Supraventricular tachycardia in children].
    Minerva medica, 1983, Dec-15, Volume: 74, Issue:47-48

    Topics: Adenosine Triphosphate; Amiodarone; Cardiac Pacing, Artificial; Child; Digitalis Glycosides; Heart D

1983
Intravenous verapamil in the treatment of paroxysmal supraventricular tachycardia in children.
    Australian paediatric journal, 1983, Volume: 19, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Inj

1983
Frequency of presumed reentry with an excitable gap in sustained ventricular tachycardia unassociated with coronary artery disease.
    The American journal of cardiology, 1993, Oct-15, Volume: 72, Issue:12

    Topics: Adolescent; Adult; Bundle of His; Bundle-Branch Block; Cardiac Pacing, Artificial; Cardiomyopathy, D

1993
Efficacy and risks of medical therapy for supraventricular tachycardia in neonates and infants.
    American heart journal, 1996, Volume: 131, Issue:1

    Topics: Anti-Arrhythmia Agents; Catheter Ablation; Digoxin; Electrocardiography; Esophagus; Female; Follow-U

1996
A 61-year-old man with Holmes' heart.
    Lancet (London, England), 1999, Feb-20, Volume: 353, Issue:9153

    Topics: Amlodipine; Anti-Arrhythmia Agents; Antihypertensive Agents; Cardiac Output, Low; Heart Defects, Con

1999
[Action of verapamil on the dynamics of heart conduction].
    Arquivos brasileiros de cardiologia, 1977, Volume: 30 Suppl 1

    Topics: Adolescent; Adult; Child; Drug Evaluation; Female; Heart Conduction System; Heart Defects, Congenita

1977
[Clinical results with verapamil in intravenous administration in the emergency therapy of cardiac arrhythmias].
    Minerva medica, 1975, May-26, Volume: 66, Issue:39

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Coronary Disease; Female; Heart

1975
Evaluation and management of supraventricular tachycardia in children.
    Annals of emergency medicine, 1991, Volume: 20, Issue:1

    Topics: Anemia; Dehydration; Dopamine; Electric Countershock; Fluid Therapy; Heart Defects, Congenital; Huma

1991
Ectopia cordis in the chick embryo heart: an experimental study.
    Teratology, 1990, Volume: 41, Issue:6

    Topics: Animals; Chick Embryo; Embryonic and Fetal Development; Heart Defects, Congenital; Ovalbumin; Verapa

1990
Protective effect of ouabain on adriamycin-induced cardiovascular anomalies in chick embryos.
    Teratology, 1989, Volume: 39, Issue:6

    Topics: Animals; Chick Embryo; Coenzymes; Dose-Response Relationship, Drug; Doxorubicin; Heart; Heart Defect

1989
Potentiating effects of verapamil on cardiovascular teratogenicity of phenobarbital in the chick embryos.
    Developmental pharmacology and therapeutics, 1988, Volume: 11, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Aorta; Calcium; Chick Embryo; Drug Synergism; Heart Defects, C

1988
Electrophysiologic effects of intravenous verapamil in children after operations for congenital heart disease.
    The American journal of cardiology, 1987, Sep-15, Volume: 60, Issue:8

    Topics: Adolescent; Child; Child, Preschool; Electrophysiology; Heart Conduction System; Heart Defects, Cong

1987
Chloral hydrate: a potential cause of arrhythmias.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:6

    Topics: Child; Child, Preschool; Chloral Hydrate; Digoxin; Female; Heart Defects, Congenital; Humans; Infant

1986
[The treatment of heart arrhythmia with the heart sympatholytic iproveratril].
    Wiener klinische Wochenschrift, 1967, Nov-17, Volume: 79, Issue:46

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Com

1967
Digitalis and atrial tachycardia with block.
    British heart journal, 1974, Volume: 36, Issue:2

    Topics: Adult; Aged; Coronary Disease; Digitoxin; Electric Countershock; Electrocardiography; Female; Heart

1974
[Effect of verapamil on coronary blood flow, oxygen utilisation and carbon dioxide production in human heart].
    Klinische Wochenschrift, 1971, Sep-01, Volume: 49, Issue:17

    Topics: Carbon Dioxide; Coronary Vessels; Electrocardiography; Heart; Heart Defects, Congenital; Heart Disea

1971