verapamil has been researched along with Gastric Ulcer in 25 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The influence of (+/-)-verapamil and hydralazine on stress- and various chemically-induced gastric ulcers in rats together with their influence on various biochemical parameters which affect the development of the induced ulcers was examined." | 7.69 | Effect of (+/-)-verapamil and hydralazine on stress- and chemically-induced gastric ulcers in rats. ( al-Bekairi, AM; al-Rajhi, AM; Tariq, M, 1994) |
| "The effect of verapamil, a calcium channel blocker, was studied against stress (cold restraint), aspirin and pylorus ligation induced gastric ulcers in rats." | 7.68 | Protection against gastric ulcer by verapamil. ( Dhawan, KN; Gupta, GP; Gupta, MB; Nath, C; Sinha, JN; Srivastava, SK; Vrat, S, 1991) |
| "), the aim of the present study was to explore the effect of this intracellular calcium antagonist on cysteamine-induced duodenal ulcers at the same low doses." | 7.68 | Examination of the potential antiulcer activity of the calcium antagonist propyl-methylenedioxyindene. III. Lack of effect on cysteamine-induced duodenal ulcers in rats. ( Rahwan, RG; Stephens, RL; Wong, WS, 1990) |
| "The effect of verapamil on ethanol-induced gastric ulceration was investigated in rats." | 7.67 | Verapamil worsens ethanol-induced gastric ulcers in rats. ( Cho, CH; Koo, MW; Ogle, CW, 1986) |
| "Verapamil-treated animals had decreased frequency and severity of gastric stress ulceration as assessed by ulcer index, ulcer grade, and number of ulcers/animal." | 5.27 | Verapamil attenuates stress-induced gastric ulceration. ( Leahy, AL; Nee, JM; Pollock, TW; Wait, RB, 1985) |
| "The influence of verapamil on stress-induced and histamine-induced gastric ulcers was investigated in rats." | 3.72 | The effects of verapamil on stress- and histamine-induced gastric lesions in rats. ( Batu, O; Erol, K; Kilic, FS; Sirmagul, B, 2004) |
| "The influence of (+/-)-verapamil and hydralazine on stress- and various chemically-induced gastric ulcers in rats together with their influence on various biochemical parameters which affect the development of the induced ulcers was examined." | 3.69 | Effect of (+/-)-verapamil and hydralazine on stress- and chemically-induced gastric ulcers in rats. ( al-Bekairi, AM; al-Rajhi, AM; Tariq, M, 1994) |
| "The effect of verapamil, a calcium channel blocker, was studied against stress (cold restraint), aspirin and pylorus ligation induced gastric ulcers in rats." | 3.68 | Protection against gastric ulcer by verapamil. ( Dhawan, KN; Gupta, GP; Gupta, MB; Nath, C; Sinha, JN; Srivastava, SK; Vrat, S, 1991) |
| "), the aim of the present study was to explore the effect of this intracellular calcium antagonist on cysteamine-induced duodenal ulcers at the same low doses." | 3.68 | Examination of the potential antiulcer activity of the calcium antagonist propyl-methylenedioxyindene. III. Lack of effect on cysteamine-induced duodenal ulcers in rats. ( Rahwan, RG; Stephens, RL; Wong, WS, 1990) |
| "The effect of verapamil on ethanol-induced gastric ulceration was investigated in rats." | 3.67 | Verapamil worsens ethanol-induced gastric ulcers in rats. ( Cho, CH; Koo, MW; Ogle, CW, 1986) |
| "Pretreatment with verapamil (2." | 1.28 | Calcium and ethanol-induced gastric mucosal damage in rats. ( Cho, CH; Ogle, CW; Wong, SH, 1991) |
| "Verapamil pretreatment (2, 4, 8 or 16 mg/kg), injected intraperitoneally 30 min before experimentation, significantly prevented stress-induced mucus depletion and gastric ulceration; however, it did not itself influence stomach wall mucus levels in nonstressed animals." | 1.27 | Effects of verapamil, carbenoxolone and N-acetylcysteine on gastric wall mucus and ulceration in stressed rats. ( Cho, CH; Koo, MW; Ogle, CW, 1986) |
| "Verapamil-treated animals had decreased frequency and severity of gastric stress ulceration as assessed by ulcer index, ulcer grade, and number of ulcers/animal." | 1.27 | Verapamil attenuates stress-induced gastric ulceration. ( Leahy, AL; Nee, JM; Pollock, TW; Wait, RB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (48.00) | 18.7374 |
| 1990's | 10 (40.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mandade, RJ | 1 |
| Sreenivas, SA | 1 |
| Sakarkar, DM | 1 |
| Choudhury, A | 1 |
| Sirmagul, B | 1 |
| Kilic, FS | 1 |
| Batu, O | 1 |
| Erol, K | 1 |
| Hung, CR | 1 |
| Omura, Y | 1 |
| al-Bekairi, AM | 1 |
| al-Rajhi, AM | 1 |
| Tariq, M | 1 |
| Gutiérrez-Cabano, CA | 1 |
| Viswanadham, CK | 1 |
| Patil, PA | 1 |
| Lutnicki, K | 1 |
| Wróbel, J | 1 |
| Ledwozyw, A | 1 |
| Trebas-Pietraś, E | 1 |
| Yegen, BC | 1 |
| Alican, I | 1 |
| Yalçin, AS | 1 |
| Oktay, S | 1 |
| Glavin, GB | 2 |
| Ogle, CW | 8 |
| Srivastava, SK | 1 |
| Nath, C | 1 |
| Gupta, MB | 1 |
| Vrat, S | 1 |
| Sinha, JN | 1 |
| Dhawan, KN | 1 |
| Gupta, GP | 1 |
| Wong, SH | 1 |
| Cho, CH | 7 |
| Wong, WS | 2 |
| Rahwan, RG | 2 |
| Stephens, RL | 1 |
| Koo, MW | 6 |
| Palombo, C | 1 |
| Mian, M | 1 |
| Bertelli, A | 1 |
| Mirossay, L | 1 |
| Nicák, A | 1 |
| Kohút, A | 1 |
| Esplugues, JV | 1 |
| Brage, R | 1 |
| Cortijo, J | 1 |
| Marti-Cabrera, M | 1 |
| Hernandez, G | 1 |
| Sarria, B | 1 |
| Esplugues, J | 1 |
| Wait, RB | 1 |
| Leahy, AL | 1 |
| Nee, JM | 1 |
| Pollock, TW | 1 |
| Tong, MC | 1 |
1 review available for verapamil and Gastric Ulcer
| Article | Year |
|---|---|
[Calcium antagonists: accounts on new perspectives of their use and an update on side effects].
Topics: Adult; Animals; Asthma; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Esophageal Ach | 1989 |
1 trial available for verapamil and Gastric Ulcer
| Article | Year |
|---|---|
Pharmacological effects of aqueous-ethanolic extract of Hibiscus rosasinensis on volume and acidity of stimulated gastric secretion.
Topics: Animals; Anti-Ulcer Agents; Calcium Channel Blockers; Carbachol; Cimetidine; Disease Models, Animal; | 2011 |
23 other studies available for verapamil and Gastric Ulcer
| Article | Year |
|---|---|
The effects of verapamil on stress- and histamine-induced gastric lesions in rats.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, | 2004 |
Protective effect of verapamil on gastric hemorrhagic ulcers in severe atherosclerotic rats.
Topics: Animals; Atherosclerosis; Calcium; Calcium Channel Blockers; Capillary Permeability; Cholesterol; Ch | 2007 |
Effects of an electrical field and its polarity on an abnormal part of the body or organ representation point associated with a diseased internal organ, and its influence on the Bi-Digital O-Ring Test (simple, non-invasive dysfunction localization method)
Topics: Acupuncture Therapy; Adult; Aspirin; Brain Ischemia; Child; Coronary Disease; Electric Stimulation T | 1982 |
Effect of (+/-)-verapamil and hydralazine on stress- and chemically-induced gastric ulcers in rats.
Topics: Animals; Disease Models, Animal; Ethanol; Gastric Acid; Gastric Mucins; Hydralazine; Indomethacin; M | 1994 |
Protection against necrotizing agents-induced gastric lesions in rats. Unrelated to inhibition of gastric motility.
Topics: Animals; Ethanol; Female; Gastrointestinal Motility; Hydrochloric Acid; Indomethacin; Male; Papaveri | 1994 |
Enhancement of anti-inflammatory activity of aspirin by verapamil.
Topics: Adrenal Glands; Animals; Aspirin; Carrageenan; Drug Synergism; Female; Foreign Bodies; Inflammation; | 1993 |
The effect of calcium ions on the intensity of peroxidation processes and the severity of ethanol-induced injury to the rat's gastric mucosa.
Topics: Animals; Calcium; Ethanol; Free Radicals; Gastric Mucosa; Lipid Peroxidation; Male; Organometallic C | 1992 |
Calcium channel blockers prevent stress-induced ulcers in rats.
Topics: Animals; Calcium Channel Blockers; Female; Gastric Mucosa; Glutathione; Lipid Peroxides; Male; Nicar | 1992 |
Adrenalectomy, but not vagotomy, reverses the worsening effect of Ca2+ blockers on ethanol-induced gastric lesions in rats.
Topics: Adrenalectomy; Animals; Dexamethasone; Drug Interactions; Ethanol; Gastric Mucosa; Injections, Intra | 1991 |
Protection against gastric ulcer by verapamil.
Topics: Animals; Aspirin; Cold Temperature; Female; Gastric Acid; Male; Pylorus; Rats; Restraint, Physical; | 1991 |
Calcium and ethanol-induced gastric mucosal damage in rats.
Topics: Animals; Calcium; Ethanol; Gastric Mucosa; Male; Rats; Rats, Inbred Strains; Stomach Ulcer; Verapami | 1991 |
Examination of the potential antiulcer activity of the calcium antagonist propyl-methylenedioxyindene. III. Lack of effect on cysteamine-induced duodenal ulcers in rats.
Topics: Aluminum Hydroxide; Animals; Antacids; Anti-Ulcer Agents; Atropine; Bethanechol Compounds; Calcium C | 1990 |
Antiulcer activity of the calcium antagonist propyl-methylenedioxyindene--I. Effect on cold/restraint stress-induced ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cold Temperature; Dose-Response Relationship, Drug; Gastric | 1990 |
The antiulcer effect of verapamil in relation to gastric calcium levels in stressed rats.
Topics: Animals; Calcium; Calcium Gluconate; Dose-Response Relationship, Drug; Egtazic Acid; Female; Rats; R | 1989 |
Effects of cold-restraint stress on gastric ulceration and motility in rats.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cold Temperature; Female; Gastric Emptying; G | 1986 |
Luminal acid in stress ulceration and the antiulcer action of verapamil in rat stomachs.
Topics: Animals; Anti-Ulcer Agents; Bethanechol Compounds; Female; Gastric Acid; Hydrochloric Acid; In Vitro | 1986 |
Verapamil and nifedipine effects on gastric acid secretion and ulcer formation in rats.
Topics: Animals; Ethanol; Gastric Acid; Gastric Mucosa; Male; Nifedipine; Rats; Rats, Inbred Strains; Refere | 1988 |
Comparison of the ulcerogenicity of indomethacin and the gastric secretion in verapamil-treated rats.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Hydroge | 1988 |
Differential effects of verapamil on various gastric lesions in rats.
Topics: Animals; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Male; Rats; Rats, Inbred Strains; | 1988 |
Effects of verapamil, carbenoxolone and N-acetylcysteine on gastric wall mucus and ulceration in stressed rats.
Topics: Acetylcysteine; Animals; Carbenoxolone; Cold Temperature; Drug Administration Schedule; Female; Gast | 1986 |
Verapamil worsens ethanol-induced gastric ulcers in rats.
Topics: Animals; Calcium Gluconate; Drug Synergism; Ethanol; Female; Rats; Rats, Inbred Strains; Stomach Ulc | 1986 |
Verapamil attenuates stress-induced gastric ulceration.
Topics: Animals; Cold Temperature; Fatty Acids; Gastrins; Male; Rats; Rats, Inbred Strains; Restraint, Physi | 1985 |
The influence of verapamil on the gastric effects of stress in rats.
Topics: Animals; Bethanechol Compounds; Female; Gastric Mucosa; Humans; Mast Cells; Rats; Rats, Inbred Strai | 1985 |