Page last updated: 2024-10-24

verapamil and Fasting Hypoglycemia

verapamil has been researched along with Fasting Hypoglycemia in 14 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Fasting Hypoglycemia: HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.

Research Excerpts

ExcerptRelevanceReference
"we observe the efficacy of verapamil and amlodipine administered simultaneously in the medical treatment of endogenous hyperinsulinemic hypoglycemia."7.73[Successful pharmacological treatment of hyperinsulinemic hypoglycemia with verapamil and amlodipine--case report]. ( Owecki, M; Sowiński, J, 2005)
"Postprandial hypoglycemia is a common complication of bariatric surgery."5.35Post-prandial hypoglycemia after bariatric surgery: pharmacological treatment with verapamil and acarbose. ( Coutinho, WF; Gonçalves, TB; Machado, NA; Moreira, RB; Moreira, RO, 2008)
"we observe the efficacy of verapamil and amlodipine administered simultaneously in the medical treatment of endogenous hyperinsulinemic hypoglycemia."3.73[Successful pharmacological treatment of hyperinsulinemic hypoglycemia with verapamil and amlodipine--case report]. ( Owecki, M; Sowiński, J, 2005)
" The results showed that a temporary relative hypoglycaemia occured in the newborns in short term as well as long term treatment with Partusisten or Partusisten in combination with Isoptin."2.64[Behaviour of serum concentrations of glucose, immunoreactive insulin and potassium ions in newborns after long term or crash treatments with Partusisten or Partusisten in combination with Isoptin (author's transl)]. ( Haller, K; Hiltmann, WD; Mohr, D; Vogel, M; Weidinger, H, 1976)
"The 2 patients with recurrences are now successfully treated with a calcium channel blocker, an approach, to our knowledge, never before reported for adult-onset nesidioblastosis."2.41Adult-onset nesidioblastosis causing hypoglycemia: an important clinical entity and continuing treatment dilemma. ( Costa, EA; Kaplan, EL; Koka, MR; Straus II, FH; Sugg, SL; Witteles, RM, 2001)
"Postprandial hypoglycemia is a common complication of bariatric surgery."1.35Post-prandial hypoglycemia after bariatric surgery: pharmacological treatment with verapamil and acarbose. ( Coutinho, WF; Gonçalves, TB; Machado, NA; Moreira, RB; Moreira, RO, 2008)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's3 (21.43)18.2507
2000's4 (28.57)29.6817
2010's2 (14.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Wang, CY1
Huang, KC1
Lu, CW1
Chu, CH1
Huang, CN1
Chen, HS1
Lee, IT1
Chen, JF1
Chen, CC1
Chen, CS1
Hsieh, CH1
Tien, KJ1
Chien, HY1
Huang, YY1
Hsu, JP1
Shane, GT1
Chang, AC1
Wu, YC1
Sheu, WH1
Hwang, JJ1
Sherwin, RS1
Øhrstrøm, CC1
Worm, D1
Højager, A1
Andersen, D1
Holst, JJ1
Kielgast, UL1
Hansen, DL1
Moreira, RO2
Moreira, RB1
Machado, NA1
Gonçalves, TB1
Coutinho, WF1
Vaisman, M1
Peixoto, PC1
Azevedo, F1
Owecki, M1
Sowiński, J1
Langer, P1
Gschwendtová, K1
Kane, C1
Shepherd, RM1
Squires, PE1
Johnson, PR1
James, RF1
Milla, PJ1
Aynsley-Green, A1
Lindley, KJ1
Dunne, MJ1
Witteles, RM1
Straus II, FH1
Sugg, SL1
Koka, MR1
Costa, EA1
Kaplan, EL1
Weidinger, H1
Mohr, D1
Haller, K1
Hiltmann, WD1
Vogel, M1
Robles, NR1
García Díaz, MC1
Fernández Mora, G1
Sánchez Casado, E1
Dessì-Fulgheri, P1
Pacifico, A1
Bandiera, F1
Rubattu, S1
Madeddu, P1
Glorioso, N1
Maioli, M1
Delitala, G1
Tomasi, P1
Rappelli, A1
Naitoh, M1
Tominaga, T1
Suzuki, H1
Saruta, T1
Deguchi, N1
Semple, CG1
Omile, C1
Buchanan, KD1
Beastall, GH1
Paterson, KR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of CS02 Tablet in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Alone[NCT03317028]Phase 2201 participants (Actual)Interventional2017-10-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for verapamil and Fasting Hypoglycemia

ArticleYear
Adult-onset nesidioblastosis causing hypoglycemia: an important clinical entity and continuing treatment dilemma.
    Archives of surgery (Chicago, Ill. : 1960), 2001, Volume: 136, Issue:6

    Topics: Adult; Age of Onset; Calcium Channel Blockers; Combined Modality Therapy; Diabetes Mellitus, Type 1;

2001
[Antiarrhythmic agent caused marked hypoglycemia in a patient receiving hemodialysis: relation with disopyramide and verapamil].
    Nihon Naibunpi Gakkai zasshi, 1988, Nov-20, Volume: 64, Issue:11

    Topics: Aged; Blood Glucose; Cardiac Complexes, Premature; Disopyramide; Drug Therapy, Combination; Glucose

1988

Trials

5 trials available for verapamil and Fasting Hypoglycemia

ArticleYear
A Randomized Controlled Trial of R-Form Verapamil Added to Ongoing Metformin Therapy in Patients with Type 2 Diabetes.
    The Journal of clinical endocrinology and metabolism, 2022, 09-28, Volume: 107, Issue:10

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Glycated H

2022
Postprandial hypoglycaemia after Roux-en-Y gastric bypass and the effects of acarbose, sitagliptin, verapamil, liraglutide and pasireotide.
    Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:9

    Topics: Acarbose; Adult; Blood Glucose; Blood Glucose Self-Monitoring; Cross-Over Studies; Female; Gastric B

2019
[Behaviour of serum concentrations of glucose, immunoreactive insulin and potassium ions in newborns after long term or crash treatments with Partusisten or Partusisten in combination with Isoptin (author's transl)].
    Zeitschrift fur Geburtshilfe und Perinatologie, 1976, Volume: 180, Issue:4

    Topics: Acid-Base Imbalance; Acidosis; Blood Glucose; Ethanolamines; Female; Fenoterol; Glycolysis; Humans;

1976
Effect of nifedipine and verapamil on carbohydrate metabolism in hypertensive patients with impaired glucose tolerance.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Adult; Arginine; Blood Glucose; Carbohydrate Metabolism; Glucose Tolerance Test; Growth Hormone; Hum

1987
Effect of oral verapamil on glibenclamide stimulated insulin secretion.
    British journal of clinical pharmacology, 1986, Volume: 22, Issue:2

    Topics: Adult; C-Peptide; Glucagon; Glucose; Glyburide; Humans; Hypoglycemia; Insulin; Insulin Secretion; Ma

1986

Other Studies

7 other studies available for verapamil and Fasting Hypoglycemia

ArticleYear
Verapamil is a potential therapy for hypoglycaemic brain injury.
    Nature reviews. Endocrinology, 2018, Volume: 14, Issue:8

    Topics: Brain; Brain Injuries; Cognitive Dysfunction; Humans; Hypoglycemia; Hypoglycemic Agents; Verapamil

2018
Post-prandial hypoglycemia after bariatric surgery: pharmacological treatment with verapamil and acarbose.
    Obesity surgery, 2008, Volume: 18, Issue:12

    Topics: Acarbose; Calcium Channel Blockers; Drug Therapy, Combination; Dumping Syndrome; Female; Gastric Byp

2008
Is long-term use of a calcium channel blocker associated with an exacerbated response of an insulinoma during selective intraarterial calcium stimulation?
    Acta radiologica (Stockholm, Sweden : 1987), 2003, Volume: 44, Issue:3

    Topics: Adult; Calcium Channel Blockers; Calcium Gluconate; Female; Humans; Hypoglycemia; Insulinoma; Pancre

2003
[Successful pharmacological treatment of hyperinsulinemic hypoglycemia with verapamil and amlodipine--case report].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2005, Volume: 19, Issue:110

    Topics: Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Female; Humans; Hyperinsulinism; Hypertensi

2005
Acute changes in biliary excretion of reverse triiodothyronine in rats after insulin-induced hypoglycemia: effect of glucose, verapamil, cycloheximide and actinomycin D.
    European journal of endocrinology, 1995, Volume: 132, Issue:5

    Topics: Animals; Bile; Cycloheximide; Dactinomycin; Glucose; Hypoglycemia; Insulin; Male; Rats; Rats, Wistar

1995
Loss of functional KATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy.
    Nature medicine, 1996, Volume: 2, Issue:12

    Topics: Action Potentials; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Calcium Channel Blocke

1996
[Poisoning by delayed-release verapamil in an uremic patient].
    Medicina clinica, 1992, Dec-05, Volume: 99, Issue:19

    Topics: Chemical and Drug Induced Liver Injury; Delayed-Action Preparations; Dose-Response Relationship, Dru

1992