Page last updated: 2024-10-24

verapamil and Endotoxemia

verapamil has been researched along with Endotoxemia in 3 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

ExcerptRelevanceReference
" Caffeine and ryanodine contractions were augmented during endotoxemia without NOS contribution."3.72The role of nitric oxide on contractile impairment during endotoxemia in rat diaphragm muscle. ( Ertunc, M; Onur, R; Sara, Y, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sara, Y1
Ertunc, M1
Onur, R1
Sermsappasuk, P1
Abdelrahman, O1
Weiss, M1
Szabó, C1
Haskó, G1
Németh, ZH1
Vizi, ES1

Other Studies

3 other studies available for verapamil and Endotoxemia

ArticleYear
The role of nitric oxide on contractile impairment during endotoxemia in rat diaphragm muscle.
    European journal of pharmacology, 2004, Nov-28, Volume: 505, Issue:1-3

    Topics: Animals; Caffeine; Diaphragm; Endotoxemia; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Indaz

2004
Cardiac pharmacokinetics and inotropic response of verapamil in rats with endotoxemia.
    Journal of pharmaceutical sciences, 2008, Volume: 97, Issue:7

    Topics: Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Endotoxemia; Heart; In Vitro Te

2008
Calcium entry blockers increase interleukin-10 production in endotoxemia.
    Shock (Augusta, Ga.), 1997, Volume: 7, Issue:4

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Endotoxemia; Interleukin-10; Interleukin-6; Lipopolysa

1997