Page last updated: 2024-10-24

verapamil and EHS Tumor

verapamil has been researched along with EHS Tumor in 9 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
" Histopathological examinations and electrocardiogram comparison demonstrated that the intelligent DDDS could markedly inhibit the growth of tumor and potentially offer an approach for safe cancer therapy."1.39cRGD-functionalized polymeric magnetic nanoparticles as a dual-drug delivery system for safe targeted cancer therapy. ( Gao, FY; Ma, M; Shen, JM; Yang, YJ; Yin, T; Yue, F; Zhang, HX, 2013)
"We have isolated a subpopulation of Ewing's sarcoma cells, from both human cell lines and human xenografts grown in immune deficient mice, which express high aldehyde dehydrogenase (ALDH(high)) activity and are enriched for clonogenicity, sphere-formation, and tumor initiation."1.36High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition. ( Awad, O; Brown, ML; Gul, N; Katuri, V; Kong, Y; Loeb, DM; O'Neill, A; Shah, P; Toretsky, JA; Yustein, JT, 2010)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Awad, O1
Yustein, JT1
Shah, P1
Gul, N1
Katuri, V1
O'Neill, A1
Kong, Y1
Brown, ML1
Toretsky, JA1
Loeb, DM1
Shen, JM1
Gao, FY1
Yin, T1
Zhang, HX1
Ma, M1
Yang, YJ1
Yue, F1
Liu, Z1
Ballinger, JR2
Rauth, AM1
Bendayan, R1
Wu, XY1
Tunggal, JK1
Melo, T1
Tannock, IF1
Madeja, Z1
Szymkiewicz, I1
Zaczek, A1
Sroka, J1
Miekus, K1
Korohoda, W1
Gossner, L1
Wittke, H1
Warzecha, A1
Sroka, R1
Ernst, H1
Meier, M1
Ell, C1
Harker, WG1
Bauer, D1
Etiz, BB1
Newman, RA1
Sikic, BI1
Biaglow, JE1
Varnes, ME1
Jacobson, B1
Suit, HD1
Sonka, J1
Stöhr, M1
Vogt-Schaden, M1
Volm, M1

Other Studies

9 other studies available for verapamil and EHS Tumor

ArticleYear
High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition.
    PloS one, 2010, Nov-11, Volume: 5, Issue:11

    Topics: Aldehyde Dehydrogenase; Animals; Antineoplastic Agents; Calcium Channel Blockers; Cell Line, Tumor;

2010
cRGD-functionalized polymeric magnetic nanoparticles as a dual-drug delivery system for safe targeted cancer therapy.
    Pharmacological research, 2013, Volume: 70, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Anti-Arrhythmia Agents; Cell Survival; Doxorubicin; Drug Carriers;

2013
Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:8

    Topics: Animals; Cell Line, Tumor; Delayed-Action Preparations; Dextrans; Doxorubicin; Drug Resistance, Neop

2003
The influence of expression of P-glycoprotein on the penetration of anticancer drugs through multicellular layers.
    International journal of cancer, 2000, Apr-01, Volume: 86, Issue:1

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neop

2000
Contact-activated migration of melanoma B16 and sarcoma XC cells.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2001, Volume: 79, Issue:4

    Topics: Animals; Cell Communication; Cell Movement; Cells, Cultured; Gadolinium; Humans; Melanoma, Experimen

2001
Verapamil and hematoporphyrin derivative for tumour destruction by photodynamic therapy.
    British journal of cancer, 1991, Volume: 64, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line; Female; Fibrosarcoma; Hematoporphyrin Derivative; Hematop

1991
Verapamil-mediated sensitization of doxorubicin-selected pleiotropic resistance in human sarcoma cells: selectivity for drugs which produce DNA scission.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Doxorubicin; Drug Resistance; Drug Synergi

1986
Effect of calcium channel blocking drugs on tumor cell oxygen utilization.
    Advances in experimental medicine and biology, 1986, Volume: 200

    Topics: Animals; Calcium Channel Blockers; Cell Line; Diltiazem; Fibrosarcoma; Glucose; Kinetics; Mammary Ne

1986
Anthracycline resistance and consequences of the in situ-in vitro transfer.
    Cytometry, 1985, Volume: 6, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Cell Cycle; Culture Media; Doxorubicin;

1985