verapamil has been researched along with Drug Refractory Epilepsy in 6 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2 of the patients (10%) had <50% seizure reduction." | 1.43 | Low dose verapamil as an adjunct therapy for medically refractory epilepsy - An open label pilot study. ( Frech, R; Frigerio, R; Maraganore, DM; Narayanan, J; Patel, V; Walters, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ilyas-Feldmann, M | 1 |
| Asselin, MC | 1 |
| Wang, S | 1 |
| McMahon, A | 1 |
| Anton-Rodriguez, J | 1 |
| Brown, G | 1 |
| Hinz, R | 1 |
| Duncan, JS | 1 |
| Sisodiya, SM | 1 |
| Koepp, M | 1 |
| Elkhayat, HA | 1 |
| Aly, RH | 1 |
| Elagouza, IA | 1 |
| El-Kabarity, RH | 1 |
| Galal, YI | 1 |
| Zybina, A | 1 |
| Anshakova, A | 1 |
| Malinovskaya, J | 1 |
| Melnikov, P | 1 |
| Baklaushev, V | 1 |
| Chekhonin, V | 1 |
| Maksimenko, O | 1 |
| Titov, S | 1 |
| Balabanyan, V | 1 |
| Kreuter, J | 1 |
| Gelperina, S | 1 |
| Abbasova, K | 1 |
| Nicita, F | 1 |
| Spalice, A | 1 |
| Raucci, U | 1 |
| Iannetti, P | 1 |
| Parisi, P | 1 |
| Shin, JW | 1 |
| Chu, K | 1 |
| Shin, SA | 1 |
| Jung, KH | 1 |
| Lee, ST | 1 |
| Lee, YS | 1 |
| Moon, J | 1 |
| Lee, DY | 1 |
| Lee, JS | 1 |
| Lee, DS | 1 |
| Lee, SK | 1 |
| Narayanan, J | 1 |
| Frech, R | 1 |
| Walters, S | 1 |
| Patel, V | 1 |
| Frigerio, R | 1 |
| Maraganore, DM | 1 |
1 review available for verapamil and Drug Refractory Epilepsy
| Article | Year |
|---|---|
The possible use of the L-type calcium channel antagonist verapamil in drug-resistant epilepsy.
Topics: Animals; Anticonvulsants; Drug Resistant Epilepsy; Humans; Models, Animal; Treatment Outcome; Verapa | 2016 |
1 trial available for verapamil and Drug Refractory Epilepsy
| Article | Year |
|---|---|
Role of P-glycoprotein inhibitors in children with drug-resistant epilepsy.
Topics: Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Double-Blind Method | 2017 |
4 other studies available for verapamil and Drug Refractory Epilepsy
| Article | Year |
|---|---|
P-glycoprotein overactivity in epileptogenic developmental lesions measured in vivo using (R)-[
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbon Radioisotopes; Drug Resistant | 2020 |
Nanoparticle-based delivery of carbamazepine: A promising approach for the treatment of refractory epilepsy.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazep | 2018 |
Clinical Applications of Simultaneous PET/MR Imaging Using (R)-[11C]-Verapamil with Cyclosporin A: Preliminary Results on a Surrogate Marker of Drug-Resistant Epilepsy.
Topics: Adult; Biomarkers; Cyclosporine; Drug Resistant Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; M | 2016 |
Low dose verapamil as an adjunct therapy for medically refractory epilepsy - An open label pilot study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Chemotherapy, Adjuvant; Drug Resistant Epilepsy; Female; H | 2016 |