verapamil has been researched along with Drug Overdose in 106 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
Excerpt | Relevance | Reference |
---|---|---|
"In an animal model of verapamil-induced shock, endogenous AVP levels increased nearly 40-fold compared with baseline levels." | 7.72 | Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study. ( Bond, GR; Johnson, SB; Sztajnkrycer, MD; Weaver, AL, 2004) |
"Noncardiogenic pulmonary edema has not been (to our knowledge) previously reported associated with a verapamil overdose." | 7.69 | Noncardiogenic pulmonary edema complicating massive verapamil overdose. ( Frumin, H; Leesar, MA; Martyn, R; Talley, JD, 1994) |
"To present three cases of slow-release verapamil poisoning that demonstrate the prolonged absorption of the drug and the role of polyethylene glycol and high-dose calcium in management." | 7.68 | Slow-release verapamil poisoning. Use of polyethylene glycol whole-bowel lavage and high-dose calcium. ( Buckley, N; Dawson, AH; Howarth, D; Whyte, IM, 1993) |
"Verapamil intoxication is a life-threatening condition that often presents with severe hemodynamic instability and requires vasopressor support." | 6.50 | Acute respiratory distress syndrome after verapamil intoxication: case report and literature review. ( Altintas, ND; Izdes, S; Soykut, C, 2014) |
" Case reports suggest that ILE may reverse hypotension caused by acute poisoning with lipophilic drugs such as verapamil, but the mechanism remains unclear." | 3.83 | In Vitro Studies Indicate Intravenous Lipid Emulsion Acts as Lipid Sink in Verapamil Poisoning. ( Dawling, S; Knollmann, BC; Kryshtal, DO; Seger, D, 2016) |
"We report a case of a 61-year-old woman treated for a suspected verapamil overdose with continuous calcium chloride infusion, resulting in severe hypercalcemia of 32." | 3.74 | A fatal case of iatrogenic hypercalcemia after calcium channel blocker overdose. ( Sim, MT; Stevenson, FT, 2008) |
"In an animal model of verapamil-induced shock, endogenous AVP levels increased nearly 40-fold compared with baseline levels." | 3.72 | Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study. ( Bond, GR; Johnson, SB; Sztajnkrycer, MD; Weaver, AL, 2004) |
"Verapamil toxicity results in hypotension, myocardial depression and disturbances in cardiac conduction." | 3.69 | Overdose of sustained-release verapamil. ( Barrow, PM; Houston, PL; Wong, DT, 1994) |
"Noncardiogenic pulmonary edema has not been (to our knowledge) previously reported associated with a verapamil overdose." | 3.69 | Noncardiogenic pulmonary edema complicating massive verapamil overdose. ( Frumin, H; Leesar, MA; Martyn, R; Talley, JD, 1994) |
"We describe two cases of pulmonary edema, bradycardia, and hypotension associated with massive verapamil overdose." | 3.69 | Massive verapamil overdose complicated by noncardiogenic pulmonary edema. ( Brass, BJ; Lipper, BL; Winchester-Penny, S, 1996) |
"For the evaluation of the hemodynamic interaction between the natural heart and an assist device, a reversible pharmacological model based on the channel blocker Verapamil under hyperkalemia, was developed for deterioration of left ventricular function." | 3.69 | Pharmacologically induced heart failure for the evaluation of circulatory assistance. ( Losert, U; Roschal, K; Schima, H; Schmidt, C; Schwendenwein, I; Wieselthaler, G; Wolner, E, 1996) |
"Hypotension, sinus node suppression, and dysrhythmias often occur with calcium channel blocker overdoses, but atrioventricular nodal block occurs more often with verapamil (chi 2 test, P < ." | 3.68 | A one-year evaluation of calcium channel blocker overdoses: toxicity and treatment. ( Borys, D; Ramoska, EA; Spiller, HA; Winter, M, 1993) |
"To present three cases of slow-release verapamil poisoning that demonstrate the prolonged absorption of the drug and the role of polyethylene glycol and high-dose calcium in management." | 3.68 | Slow-release verapamil poisoning. Use of polyethylene glycol whole-bowel lavage and high-dose calcium. ( Buckley, N; Dawson, AH; Howarth, D; Whyte, IM, 1993) |
"Verapamil intoxication is a life-threatening condition that often presents with severe hemodynamic instability and requires vasopressor support." | 2.50 | Acute respiratory distress syndrome after verapamil intoxication: case report and literature review. ( Altintas, ND; Izdes, S; Soykut, C, 2014) |
" In spite of the low dose ingested, the postmortem cardiac blood verapamil level was clearly toxic (6000 ng/mL, or 6 mg/L)." | 2.44 | Verapamil toxicity: an unusual case report and review of the literature. ( Batalis, NI; Harley, RA; Schandl, CA, 2007) |
"Verapamil 99 is a commonly prescribed medicine for treatment of hypertension, angina, and migraine headache." | 2.39 | Massive overdose of sustained-release verapamil: a case report and review of literature. ( Ashraf, M; Chaudhary, K; Nelson, J; Thompson, W, 1995) |
" Although specific recommendations for calcium dosing in the overdose situation have not been rigorously studied, maintenance of a normal serum ionized calcium concentration is suggested." | 2.38 | Verapamil overdose: case report and review of the literature. ( Crain, JL; Edwards, TD; Stiller, RA; Watling, SM, 1992) |
"Verapamil intoxication was confirmed, and therapy was adjusted accordingly." | 1.43 | Severe verapamil intoxication despite correct use of low-dose verapamil. ( Bijlstra, PJ; Bollen, PD; Brands, E; Mandigers, L, 2016) |
" IFE therapy is being recommended by US PCCs; protocols and dosing regimens are nearly uniform." | 1.39 | Lipid rescue 911: Are poison centers recommending intravenous fat emulsion therapy for severe poisoning? ( Christian, MR; Mycyk, MB; Pallasch, EM; Wahl, M, 2013) |
" In patients with life-saving use in suicide attempts important role in addition to medication dosage plays an elapsed time of their consumption and speed of action taken to remove and prevent absorbtion the poison", as well as close supervision in the intensive care unit." | 1.38 | [Drugs acting on the heart-conductive system in suicide attempts]. ( Dabek, J; Jakubowski, D; Rychlik, W; Stachoń, K, 2012) |
"Verapamil toxicity was achieved by a constant infusion of 15 mg/kg/hr." | 1.35 | Determining the optimal dose of intravenous fat emulsion for the treatment of severe verapamil toxicity in a rodent model. ( Bania, TC; Chu, J; Medlej, K; Perez, E, 2008) |
" The decline in plasma verapamil and norverapamil concentrations followed first-order kinetics, and the half-life of verapamil was 7." | 1.30 | Pharmacokinetics of verapamil in overdose. ( Kivistö, KT; Neuvonen, PJ; Tarssanen, L, 1997) |
"A patient with cardiac arrest after severe verapamil intoxication." | 1.30 | Successful resuscitation of a verapamil-intoxicated patient with percutaneous cardiopulmonary bypass. ( Behringer, W; Domanovits, H; Holzer, M; Schoerkhuber, W; Sterz, F; Stimpfl, T; Weinmar, D; Weinstabl, C, 1999) |
"Amrinone and glucagon have been used separately and in combination with other agents in the treatment of calcium channel blocker overdose." | 1.29 | Use of amrinone and glucagon in a case of calcium channel blocker overdose. ( Otten, EJ; Spadafora, MP; Wolf, LR, 1993) |
"Verapamil overdose, because of its frequency and severity, represents a significant problem for the emergency physician." | 1.29 | Cardiac dysrhythmias in severe verapamil overdose: characterization with a canine model. ( Koury, SI; Stone, CK; Thomas, SH, 1996) |
" At severely toxic levels when arterial blood pressure fell by 50%, all three drugs decreased cardiac output." | 1.28 | Effects of calcium channel blocker overdose-induced toxicity in the conscious dog. ( Gambone, LM; Schoffstall, JM; Shaw, RP; Sit, SP; Spivey, WH, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (0.94) | 18.7374 |
1990's | 48 (45.28) | 18.2507 |
2000's | 24 (22.64) | 29.6817 |
2010's | 29 (27.36) | 24.3611 |
2020's | 4 (3.77) | 2.80 |
Authors | Studies |
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Eijsink, JFH | 1 |
Grol, BJH | 1 |
Naber, HR | 1 |
van Egmond, PS | 1 |
Lodhi, FAK | 1 |
Shogren, SL | 1 |
Vedre, JG | 1 |
Haque, N | 1 |
Reriani, M | 1 |
Ali, R | 1 |
Gau, N | 1 |
Grossman, BJ | 1 |
Kohli, U | 1 |
Lam, S | 1 |
Eason, H | 1 |
Jani, P | 1 |
Olson, KR | 2 |
Levine, M | 4 |
Curry, SC | 2 |
Padilla-Jones, A | 2 |
Ruha, AM | 3 |
Christian, MR | 1 |
Pallasch, EM | 1 |
Wahl, M | 1 |
Mycyk, MB | 1 |
Pfeffer, AN | 2 |
Williams, SR | 2 |
Price, D | 1 |
Radke, J | 1 |
Albertson, T | 1 |
Chan, TB | 1 |
Chan, YC | 1 |
Lau, FL | 1 |
Curry, S | 1 |
Holger, JS | 1 |
Engebretsen, KM | 1 |
Stellpflug, SJ | 1 |
Cole, JB | 1 |
Kerns, W | 1 |
Kline, JA | 1 |
Izdes, S | 1 |
Altintas, ND | 1 |
Soykut, C | 1 |
Martin, C | 1 |
Gonzalez, H | 1 |
Ruiz, S | 1 |
Ribes, D | 1 |
Franchitto, N | 1 |
Minville, V | 1 |
Sampson, CS | 1 |
Bedy, SM | 1 |
Cibickova, L | 1 |
Caran, T | 1 |
Dobias, M | 1 |
Ondra, P | 1 |
Vorisek, V | 1 |
Cibicek, N | 1 |
Kryshtal, DO | 1 |
Dawling, S | 1 |
Seger, D | 1 |
Knollmann, BC | 1 |
Déniel, A | 1 |
Fedrizzi, S | 1 |
Lelong-Boulouard, V | 1 |
Coquerel, A | 1 |
Alexandre, J | 1 |
Mandigers, L | 1 |
Bollen, PD | 1 |
Bijlstra, PJ | 1 |
Brands, E | 1 |
Perez, E | 1 |
Bania, TC | 2 |
Medlej, K | 1 |
Chu, J | 1 |
Perbet, S | 1 |
Constantin, JM | 1 |
Guérin, R | 1 |
Faure, M | 1 |
Brugère, C | 1 |
Da Inès, D | 1 |
Joubert, J | 1 |
Bazin, JE | 1 |
Pillai, U | 1 |
Muzaffar, J | 1 |
Sen, S | 1 |
Yancey, A | 1 |
Varpula, T | 1 |
Rapola, J | 1 |
Sallisalmi, M | 1 |
Kurola, J | 1 |
Cohen, V | 1 |
Jellinek, SP | 1 |
Fancher, L | 1 |
Sangwan, G | 1 |
Wakslak, M | 1 |
Marquart, E | 1 |
Farahani, C | 1 |
Young, AC | 1 |
Velez, LI | 1 |
Kleinschmidt, KC | 1 |
Graudins, A | 1 |
George, M | 1 |
Senthilkumaran, S | 1 |
Balamurgan, N | 1 |
Sweni, S | 1 |
Thirumalaikolundusubramanian, P | 1 |
Doğan, M | 1 |
Basaranoglu, M | 1 |
Peker, E | 1 |
Akbayram, S | 1 |
Sahin, M | 1 |
Uner, A | 1 |
Caksen, H | 1 |
Mégarbane, B | 1 |
Karyo, S | 1 |
Abidi, K | 1 |
Delhotal-Landes, B | 1 |
Aout, M | 1 |
Sauder, P | 1 |
Baud, FJ | 1 |
Franxman, TJ | 1 |
Al-Nabhan, M | 1 |
Cavallazzi, RS | 1 |
Speak, AJ | 1 |
Sein Anand, J | 1 |
Barwina, M | 1 |
Wiśniewska, A | 1 |
French, D | 1 |
Armenian, P | 1 |
Ruan, W | 1 |
Wong, A | 1 |
Drasner, K | 1 |
Wu, AH | 1 |
Pichon, N | 1 |
Dugard, A | 1 |
Clavel, M | 1 |
Amiel, JB | 1 |
François, B | 1 |
Vignon, P | 1 |
Deters, M | 1 |
Bergmann, I | 1 |
Enden, G | 1 |
Kutz, S | 1 |
Liebetrau, G | 1 |
Plenert, B | 1 |
Prasa, D | 1 |
Hentschel, H | 1 |
Dabek, J | 1 |
Stachoń, K | 1 |
Jakubowski, D | 1 |
Rychlik, W | 1 |
Sami Karti, S | 1 |
Ulusoy, H | 1 |
Yandi, M | 1 |
Gündüz, A | 1 |
Koşucu, M | 1 |
Erol, K | 1 |
Ratip, S | 1 |
Gokel, Y | 1 |
Paydas, S | 1 |
Acikalin, A | 1 |
Bozkurt, A | 1 |
Kinoshita, H | 1 |
Taniguchi, T | 1 |
Nishiguchi, M | 1 |
Ouchi, H | 1 |
Minami, T | 1 |
Utsumi, T | 1 |
Motomura, H | 1 |
Tsuda, T | 1 |
Ohta, T | 1 |
Aoki, S | 1 |
Komeda, M | 1 |
Kamamoto, T | 1 |
Kubota, A | 1 |
Fuke, C | 1 |
Arao, T | 1 |
Miyazaki, T | 1 |
Hishida, S | 1 |
Kostrzewa, A | 1 |
Klimaszyk, D | 1 |
Sandroni, C | 1 |
Cavallaro, F | 1 |
Addario, C | 1 |
Ferro, G | 1 |
Gallizzi, F | 1 |
Antonelli, M | 1 |
Sztajnkrycer, MD | 1 |
Bond, GR | 1 |
Johnson, SB | 1 |
Weaver, AL | 1 |
Manov, I | 1 |
Motanis, H | 1 |
Frumin, I | 1 |
Iancu, TC | 1 |
Wilimowska, J | 1 |
Piekoszewski, W | 1 |
Krzyanowska-Kierepka, E | 1 |
Florek, E | 1 |
Pohler, HF | 1 |
Batalis, NI | 1 |
Harley, RA | 1 |
Schandl, CA | 1 |
Fiszer, M | 1 |
Kołaciński, Z | 1 |
Rechciński, T | 1 |
Boyer, EW | 1 |
Pozner, CN | 1 |
Geib, AJ | 1 |
Thomsen, T | 1 |
Mick, N | 1 |
Thomas, SH | 4 |
Johansen, KK | 1 |
Belhage, B | 1 |
Winchester, DE | 1 |
Holstege, C | 1 |
Sim, MT | 1 |
Stevenson, FT | 1 |
Ashraf, M | 1 |
Chaudhary, K | 1 |
Nelson, J | 1 |
Thompson, W | 1 |
Buckley, CD | 1 |
Aronson, JK | 1 |
Lip, GY | 2 |
Ferner, RE | 1 |
Huelmos, A | 1 |
Alegría, E | 1 |
Vázquez, C | 1 |
Stone, CK | 4 |
May, WA | 1 |
Carroll, R | 1 |
Roberge, RJ | 1 |
Martin, TG | 1 |
Hodgman, M | 1 |
Benitez, JG | 1 |
Brunswick, JE | 1 |
Barrow, PM | 1 |
Houston, PL | 1 |
Wong, DT | 1 |
Rodríguez Blanco, VM | 2 |
Rodríguez Suárez, ML | 1 |
Möller Bustinza, I | 1 |
Castellanos Martínez, E | 1 |
Puebla Rojo, V | 1 |
Barriales Alvarez, V | 2 |
Cortina Llosa, A | 1 |
Zimmers, T | 2 |
Hofer, CA | 1 |
Smith, JK | 1 |
Tenholder, MF | 1 |
Leesar, MA | 1 |
Martyn, R | 1 |
Talley, JD | 1 |
Frumin, H | 1 |
Cleary, JD | 1 |
Hayman, J | 1 |
Sherwood, J | 1 |
Lasala, GP | 1 |
Piazza-Hepp, T | 1 |
Chia-Lin, Y | 1 |
Ramoska, EA | 1 |
Spiller, HA | 2 |
Winter, M | 1 |
Borys, D | 1 |
Buckley, N | 1 |
Dawson, AH | 1 |
Howarth, D | 1 |
Whyte, IM | 1 |
Bonechi, F | 1 |
Brandinelli Geri, A | 1 |
Maioli, M | 1 |
Ieri, A | 1 |
Doyon, S | 1 |
Roberts, JR | 1 |
Wolf, LR | 1 |
Spadafora, MP | 1 |
Otten, EJ | 1 |
Honan, MP | 1 |
Stankevicute, N | 1 |
van Wanroy, JL | 1 |
de Weerdt, O | 1 |
Joore, JC | 1 |
van der Hoven, B | 1 |
van de Wiel, A | 1 |
Gutierrez, H | 1 |
Jorgensen, M | 1 |
Brass, BJ | 1 |
Winchester-Penny, S | 1 |
Lipper, BL | 1 |
Smilkstein, MJ | 1 |
Koury, SI | 3 |
Low, RB | 1 |
Schmidt, C | 1 |
Schwendenwein, I | 1 |
Wieselthaler, G | 1 |
Roschal, K | 1 |
Schima, H | 1 |
Losert, U | 1 |
Wolner, E | 1 |
Li Saw Hee, FL | 1 |
Kivistö, KT | 1 |
Neuvonen, PJ | 1 |
Tarssanen, L | 1 |
Liao, WB | 1 |
Bullard, MJ | 1 |
Kuo, CT | 1 |
Hsiao, CT | 1 |
Chu, PH | 1 |
Chiang, CW | 1 |
Manoach, SM | 1 |
Hamilton, RJ | 1 |
Barriales Villa, R | 1 |
Batalla Celorio, A | 1 |
Kalman, S | 1 |
Berg, S | 1 |
Lisander, B | 1 |
Oe, H | 1 |
Taniura, T | 1 |
Ohgitani, N | 1 |
Holzer, M | 1 |
Sterz, F | 1 |
Schoerkhuber, W | 1 |
Behringer, W | 1 |
Domanovits, H | 1 |
Weinmar, D | 1 |
Weinstabl, C | 1 |
Stimpfl, T | 1 |
Ori, Y | 1 |
Korzets, A | 1 |
Caneti, M | 1 |
Weinstein, T | 1 |
Chagnac, A | 1 |
Salman, H | 1 |
Malachi, T | 1 |
Gafter, U | 1 |
Kuhlmann, U | 1 |
Schoenemann, H | 1 |
Müller, TF | 1 |
Keuchel, M | 1 |
Lange, H | 1 |
Blaufeux, B | 1 |
Hughes, S | 1 |
Almond, GL | 1 |
Homel, P | 1 |
Vadlamudi, L | 1 |
Wijdicks, EF | 1 |
Ramo, MP | 1 |
Grupp, I | 1 |
Pesola, MK | 1 |
Heikkila, J | 1 |
Luomanmaki, K | 1 |
Schroder, T | 1 |
Grupp, G | 1 |
Shah, AR | 1 |
Passalacqua, BR | 1 |
Watling, SM | 1 |
Crain, JL | 1 |
Edwards, TD | 1 |
Stiller, RA | 1 |
MacDonald, D | 1 |
Alguire, PC | 1 |
Kuo, MJ | 1 |
Tseng, YZ | 1 |
Chen, TF | 1 |
Fong, DE | 1 |
Frierson, J | 1 |
Bailly, D | 1 |
Shultz, T | 1 |
Sund, S | 1 |
Dimas, A | 1 |
Watson, NA | 1 |
FitzGerald, CP | 1 |
Schoffstall, JM | 1 |
Spivey, WH | 1 |
Gambone, LM | 1 |
Shaw, RP | 1 |
Sit, SP | 1 |
Meyers, A | 1 |
Ziemba, T | 1 |
Riley, M | 1 |
Spurlock, BW | 1 |
Virani, NA | 1 |
Henry, CA | 1 |
Minella, RA | 1 |
Schulman, DS | 1 |
Rankin, RJ | 1 |
Edwards, IR | 1 |
Horowitz, BZ | 1 |
Rhee, KJ | 1 |
14 reviews available for verapamil and Drug Overdose
Article | Year |
---|---|
Hypocalcaemia after an occult calcium channel blocker overdose: a case report and literature review.
Topics: Adult; Calcium; Calcium Channel Blockers; Critical Illness; Drug Overdose; Female; Humans; Hypocalce | 2014 |
Acute respiratory distress syndrome after verapamil intoxication: case report and literature review.
Topics: Adult; Drug Overdose; Female; Humans; Male; Respiratory Distress Syndrome; Verapamil; Young Adult | 2014 |
Tarka® (trandolapril/verapamil hydrochloride extended-release) overdose.
Topics: Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Co | 2011 |
Hepatotoxicity of anti-inflammatory and analgesic drugs: ultrastructural aspects.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Ster | 2006 |
A little goes a long way: Clinical management of calcium channel blocker overdose.
Topics: Adult; Calcium Channel Blockers; Calcium Chloride; Drug Overdose; Enterosorption; Female; Glucose; H | 2006 |
Verapamil toxicity: an unusual case report and review of the literature.
Topics: Accidents; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Drug Overdose; Fema | 2007 |
Massive overdose of sustained-release verapamil: a case report and review of literature.
Topics: Calcium Gluconate; Combined Modality Therapy; Delayed-Action Preparations; Drug Overdose; Female; Gl | 1995 |
Poisoning with anti-hypertensive drugs: calcium antagonists.
Topics: Age Factors; Antihypertensive Agents; Calcium; Diltiazem; Drug Overdose; Humans; Hypertension; Nifed | 1995 |
[The toxicity of slow-release verapamil and chronic kidney disease].
Topics: Aged; Delayed-Action Preparations; Drug Overdose; Female; Humans; Hypertension; Kidney Failure, Chro | 1994 |
[A suicide attempt with oral verapamil: a case report].
Topics: Administration, Oral; Adult; Drug Overdose; Electrocardiography; Heart Block; Humans; Male; Suicide, | 1993 |
Verapamil intoxication: a literature review of overdoses and discussion of therapeutic options.
Topics: Adult; Drug Overdose; Fatal Outcome; Humans; Male; Treatment Outcome; Verapamil | 1993 |
[The massive ingestion of verapamil with suicidal intent].
Topics: Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Drug Overdose; Humans; Male; Suicide, Attem | 1997 |
Verapamil overdose: case report and review of the literature.
Topics: Adolescent; Cardiac Pacing, Artificial; Charcoal; Drug Overdose; Fluid Therapy; Gastric Lavage; Hear | 1992 |
Massive verapamil ingestion: a report of two cases and a review of the literature.
Topics: Adrenergic alpha-Agonists; Adult; Calcium; Cardiovascular Agents; Drug Overdose; Female; Glucagon; H | 1989 |
92 other studies available for verapamil and Drug Overdose
Article | Year |
---|---|
Comparison of two treatments for verapamil overdose.
Topics: Calcium Channel Blockers; Drug Overdose; Humans; Verapamil | 2023 |
Calcium Channel Blocker Toxicity Causing Acute Respiratory Distress Syndrome: A Commonly Used Drug Triggering a Life-Threatening Condition.
Topics: Adult; Anticonvulsants; Calcium Channel Blockers; Clonazepam; Drug Overdose; Female; Humans; Respira | 2020 |
Therapeutic plasma exchange for iatrogenic hypertrigylceridemia.
Topics: Aged; Drug Overdose; Fat Emulsions, Intravenous; Female; Glucose; Humans; Hypertriglyceridemia; Iatr | 2020 |
Heart Rhythm Abnormalities Following Acute Verapamil Overdose.
Topics: Drug Overdose; Heart Rate; Humans; Verapamil | 2021 |
What is the best treatment for acute calcium channel blocker overdose?
Topics: Calcium Channel Blockers; Critical Care; Diltiazem; Drug Overdose; Female; Humans; Male; Vasoconstri | 2013 |
Critical care management of verapamil and diltiazem overdose with a focus on vasopressors: a 25-year experience at a single center.
Topics: Adolescent; Adult; Aged; Arizona; Calcium Channel Blockers; Critical Care; Diltiazem; Drug Overdose; | 2013 |
Lipid rescue 911: Are poison centers recommending intravenous fat emulsion therapy for severe poisoning?
Topics: Acute Disease; Adult; Amitriptyline; Bupivacaine; Drug Overdose; Fat Emulsions, Intravenous; Guideli | 2013 |
Annals of Emergency Medicine Journal Club. Treatment of calcium channel blocker poisoning: should we re-prioritize our potpourri of treatment options?
Topics: Calcium Channel Blockers; Critical Care; Diltiazem; Drug Overdose; Female; Humans; Male; Vasoconstri | 2013 |
Ischemia complications after calcium channel blocker poisoning.
Topics: Calcium Channel Blockers; Critical Care; Diltiazem; Drug Overdose; Female; Humans; Male; Vasoconstri | 2014 |
In reply.
Topics: Calcium Channel Blockers; Critical Care; Diltiazem; Drug Overdose; Female; Humans; Male; Vasoconstri | 2014 |
Critical care management of verapamil and diltiazem overdose with a focus on vasopressors: a 25-year experience at a single center.
Topics: Calcium Channel Blockers; Critical Care; Diltiazem; Drug Overdose; Female; Humans; Male; Vasoconstri | 2014 |
Insulin for calcium channel toxicity.
Topics: Calcium Channel Blockers; Critical Care; Diltiazem; Drug Overdose; Female; Humans; Male; Vasoconstri | 2014 |
In reply.
Topics: Calcium Channel Blockers; Critical Care; Diltiazem; Drug Overdose; Female; Humans; Male; Vasoconstri | 2014 |
Annals of Emergency Medicine Journal Club. Treatment of calcium channel blocker poisoning: should we reprioritize our potpourri of treatment options?: answers to the September 2013 Journal Club questions.
Topics: Calcium Channel Blockers; Critical Care; Diltiazem; Drug Overdose; Female; Humans; Male; Vasoconstri | 2014 |
Acute respiratory distress syndrome following verapamil overdose treated with intravenous lipid emulsion: a rare life-threatening complication.
Topics: Calcium Channel Blockers; Drug Overdose; Extracorporeal Membrane Oxygenation; Fat Emulsions, Intrave | 2014 |
Lipid emulsion therapy given intraosseously in massive verapamil overdose.
Topics: Anti-Arrhythmia Agents; Drug Overdose; Fat Emulsions, Intravenous; Fatal Outcome; Female; Humans; In | 2015 |
Multi-drug intoxication fatality involving atorvastatin: A case report.
Topics: Acute Kidney Injury; Aged; Alcoholics; Anthraquinones; Anti-Inflammatory Agents; Antihypertensive Ag | 2015 |
In Vitro Studies Indicate Intravenous Lipid Emulsion Acts as Lipid Sink in Verapamil Poisoning.
Topics: Absorption, Physicochemical; Animals; Calcium Channel Blockers; Calcium Signaling; Cardiotoxicity; C | 2016 |
Fatal Cardiac Arrest Associated with Concomitant Bisoprolol and Verapamil Overdose.
Topics: Aged, 80 and over; Antihypertensive Agents; Bisoprolol; Calcium Channel Blockers; Drug Overdose; Ech | 2016 |
Severe verapamil intoxication despite correct use of low-dose verapamil.
Topics: Bradycardia; Calcium Channel Blockers; Cytochrome P-450 Enzyme System; Dose-Response Relationship, D | 2016 |
Determining the optimal dose of intravenous fat emulsion for the treatment of severe verapamil toxicity in a rodent model.
Topics: Acid-Base Equilibrium; Animals; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Do | 2008 |
Non-occlusive colonic ischemia induced by verapamil ER overdose.
Topics: Colon; Drug Overdose; Humans; Ischemia; Male; Middle Aged; Suicide, Attempted; Vasodilator Agents; V | 2009 |
Grapefruit juice and verapamil: a toxic cocktail.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Citrus par | 2009 |
Treatment of serious calcium channel blocker overdose with levosimendan, a calcium sensitizer.
Topics: Acidosis, Lactic; Amlodipine; Calcium Channel Blockers; Cardiotonic Agents; Coma; Drug Overdose; Ech | 2009 |
Intravenous fat emulsion therapy for intentional sustained-release verapamil overdose.
Topics: Adult; Bradycardia; Calcium Channel Blockers; Delayed-Action Preparations; Drug Overdose; Electrocar | 2009 |
Letter regarding levosimendan in a rat model of severe verapamil poisoning.
Topics: Animals; Antidotes; Cardiotonic Agents; Cardiovascular Agents; Disease Models, Animal; Drug Overdose | 2009 |
Severe lactic acidosis in a patient after calcium channel blocker toxicity.
Topics: Acidosis, Lactic; Adolescent; Calcium Channel Blockers; Diagnosis, Differential; Drug Overdose; Huma | 2010 |
Acute episode of reversible blindness after an overdose of beta blockers and calcium channel antagonist.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Blindness; Calcium Channel Blockers; Drug Overdose; F | 2011 |
Tarka® overdose in a young child.
Topics: Child, Preschool; Drug Combinations; Drug Overdose; Electrocardiography; Female; Humans; Indoles; Pa | 2011 |
Predictors of mortality in verapamil overdose: usefulness of serum verapamil concentrations.
Topics: Adult; Calcium Channel Blockers; Critical Care; Delayed-Action Preparations; Drug Overdose; Female; | 2011 |
Lipid emulsion therapy for verapamil overdose.
Topics: Adult; Calcium Gluconate; Charcoal; Combined Modality Therapy; Drug Overdose; Fat Emulsions, Intrave | 2011 |
[The lower legs amputation--rare side effects of acute poisoning].
Topics: Amputation, Surgical; Drug Combinations; Drug Overdose; Ethanol; Humans; Indoles; Ischemia; Leg; Mal | 2010 |
Serum verapamil concentrations before and after Intralipid® therapy during treatment of an overdose.
Topics: Calcium Channel Blockers; Drug Overdose; Emulsions; Fat Emulsions, Intravenous; Humans; Male; Middle | 2011 |
Extracorporeal albumin dialysis in three cases of acute calcium channel blocker poisoning with life-threatening refractory cardiogenic shock.
Topics: Adolescent; Albumins; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Overdos | 2012 |
Calcium channel antagonist exposures reported to the Poisons Information Center Erfurt.
Topics: Adolescent; Adult; Age Distribution; Aged; Calcium Channel Blockers; Child; Dihydropyridines; Diltia | 2011 |
[Drugs acting on the heart-conductive system in suicide attempts].
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Calcium Channel Blockers; Causality; Comorbidity; Dru | 2012 |
Non-cardiogenic pulmonary oedema in the course of verapamil intoxication.
Topics: Adult; Drug Overdose; Female; Humans; Poisoning; Pulmonary Edema; Respiration, Artificial; Suicide, | 2002 |
High-dose verapamil + trandolapril-induced thrombotic microangiopathy.
Topics: Adult; Anemia, Hemolytic; Blood Cell Count; Drug Overdose; Female; Hematocrit; Hemoglobins; Humans; | 2002 |
An autopsy case of combined drug intoxication involving verapamil, metoprolol and digoxin.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Digoxin; Drug | 2003 |
[ECG disturbances as a consequence of cardiac drugs overdose].
Topics: Adult; Aged; Bradycardia; Cardiotonic Agents; Drug Overdose; Electrocardiography; Female; Humans; Ma | 2003 |
Successful treatment with enoximone for severe poisoning with atenolol and verapamil: a case report.
Topics: Adrenergic Agonists; Anti-Arrhythmia Agents; Atenolol; Blood Pressure; Cardiac Output; Cardiotonic A | 2004 |
Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Dog | 2004 |
Monitoring of verapamil enantiomers concentration in overdose.
Topics: Blood Pressure; Calcium Channel Blockers; Drug Overdose; Female; Humans; Metabolic Clearance Rate; M | 2006 |
[The application of 4-aminopyridine in calcium channel inhibitors acute poisoning].
Topics: 4-Aminopyridine; Acute Disease; Adrenergic beta-Antagonists; Adult; Antidotes; Antihypertensive Agen | 2007 |
Assessment of hyperglycemia after calcium channel blocker overdoses involving diltiazem or verapamil.
Topics: Adult; Aged; Blood Glucose; Calcium Channel Blockers; Diltiazem; Drug Overdose; Humans; Hyperglycemi | 2007 |
[A 48-year-old woman's survival from a massive verapamil overdose].
Topics: Calcium Channel Blockers; Drug Overdose; Female; Humans; Middle Aged; Poisoning; Suicide, Attempted; | 2007 |
Inclusion of patients who overdose with dihydropyridine calcium channel blockers would potentially increase clinical utility of hyperglycemia.
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Overdose; Heart Rate; Humans; Hyperglyce | 2008 |
A fatal case of iatrogenic hypercalcemia after calcium channel blocker overdose.
Topics: Calcium Channel Blockers; Drug Overdose; Fatal Outcome; Female; Humans; Hypercalcemia; Middle Aged; | 2008 |
Prolonged half-life of verapamil in a case of overdose: implications for therapy.
Topics: Drug Overdose; Half-Life; Humans; Male; Middle Aged; Verapamil | 1995 |
Treatment of verapamil overdose with glucagon in dogs.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Drug Overdose; Glucagon; Heart Rate; Random Allocatio | 1995 |
Supraventricular tachyarrhythmia associated with baclofen overdose.
Topics: Adenosine; Adult; Baclofen; Drug Overdose; Electrocardiography; Humans; Intubation, Intratracheal; M | 1994 |
Overdose of sustained-release verapamil.
Topics: Adult; Delayed-Action Preparations; Drug Overdose; Female; Heart Block; Humans; Hypotension; Time Fa | 1994 |
Cases in electrocardiography.
Topics: Bradycardia; Drug Overdose; Electrocardiography; Female; Humans; Male; Middle Aged; Nicotine; Verapa | 1994 |
Noncardiogenic pulmonary edema complicating massive verapamil overdose.
Topics: Adult; Drug Overdose; Dyspnea; Female; Humans; Hypotension; Hypoxia; Pulmonary Edema; Verapamil | 1994 |
Amphotericin B overdose in pediatric patients with associated cardiac arrest.
Topics: Amphotericin B; Arrhythmias, Cardiac; Candidiasis; Child; Child, Preschool; Drug Overdose; Female; H | 1993 |
Cases in electrocardiography.
Topics: Adult; Drug Overdose; Electrocardiography; Emergency Service, Hospital; Female; Heart Block; Humans; | 1993 |
A one-year evaluation of calcium channel blocker overdoses: toxicity and treatment.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atropine; Calcium; Calcium Channel Blockers; Child; C | 1993 |
Slow-release verapamil poisoning. Use of polyethylene glycol whole-bowel lavage and high-dose calcium.
Topics: Adolescent; Adult; Calcium; Charcoal; Delayed-Action Preparations; Drug Overdose; Female; Gastric La | 1993 |
[Verapamil poisoning for suicidal purposes. A case report].
Topics: Aged; Aged, 80 and over; Drug Overdose; Female; Humans; Suicide, Attempted; Verapamil | 1993 |
The use of glucagon in a case of calcium channel blocker overdose.
Topics: Acute Disease; Aged; Bradycardia; Dobutamine; Dopamine; Drug Overdose; Drug Therapy, Combination; Fe | 1993 |
Use of amrinone and glucagon in a case of calcium channel blocker overdose.
Topics: Adult; Amrinone; Drug Overdose; Drug Therapy, Combination; Female; Glucagon; Humans; Hypotension; Ve | 1993 |
A case of calcium channel blocker overdose.
Topics: Adult; Calcium Channel Blockers; Drug Overdose; Female; Heart Block; Humans; Suicide, Attempted; Ver | 1995 |
[Overdose of a drug with delayed action].
Topics: Adult; Calcium Channel Blockers; Critical Care; Delayed-Action Preparations; Drug Overdose; Fatal Ou | 1996 |
Colonic ischemia after verapamil overdose.
Topics: Colon; Drug Overdose; Female; Humans; Ischemia; Middle Aged; Suicide, Attempted; Verapamil | 1996 |
Massive verapamil overdose complicated by noncardiogenic pulmonary edema.
Topics: Adult; Bradycardia; Calcium Channel Blockers; Combined Modality Therapy; Critical Care; Drug Overdos | 1996 |
Perfusion salad: making sense of verapamil overdose.
Topics: Animals; Calcium Channel Blockers; Clinical Trials as Topic; Drug Overdose; Humans; Receptors, Adren | 1996 |
Glucagon and phenylephrine combination vs glucagon alone in experimental verapamil overdose.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Antidotes; Calcium Channel Blockers; Dogs; | 1996 |
Pharmacologically induced heart failure for the evaluation of circulatory assistance.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Cattle; | 1996 |
Amrinone as an antidote in experimental verapamil overdose.
Topics: Amrinone; Animals; Antidotes; Dogs; Drug Overdose; Hemodynamics; Verapamil | 1996 |
Case report: fatal verapamil overdosage despite intensive therapy and use of high dose intravenous calcium.
Topics: Calcium; Dose-Response Relationship, Drug; Drug Overdose; Fatal Outcome; Female; Humans; Injections, | 1996 |
Cardiac dysrhythmias in severe verapamil overdose: characterization with a canine model.
Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Dogs; Drug Overdose; Electrocardiography; | 1996 |
Pharmacokinetics of verapamil in overdose.
Topics: Adult; Calcium Channel Blockers; Drug Overdose; Female; Half-Life; Humans; Male; Middle Aged; Poison | 1997 |
Anticholinergic overdose induced torsade de pointes successfully treated with verapamil.
Topics: Adolescent; Antidepressive Agents; Antipsychotic Agents; Cholinergic Antagonists; Drug Overdose; Fem | 1996 |
Amrinone and verapamil overdose study design.
Topics: Amrinone; Animals; Antidotes; Dogs; Drug Overdose; Research Design; Verapamil | 1997 |
Combined overdose with verapamil and atenolol: treatment with high doses of adrenergic agonists.
Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Atenolol; Calcium Channel Blockers; Drug Overdose; | 1998 |
A case of severe verapamil overdose.
Topics: Aged; Calcium Channel Blockers; Drug Overdose; Female; Humans; Japan; Suicide, Attempted; Verapamil | 1998 |
Successful resuscitation of a verapamil-intoxicated patient with percutaneous cardiopulmonary bypass.
Topics: Adult; Calcium Channel Blockers; Cardiopulmonary Bypass; Drug Overdose; Electrocardiography; Emergen | 1999 |
Lymphocytic intracellular calcium in a patient with complicated verapamil overdose.
Topics: Calcium; Calcium Channel Blockers; Drug Overdose; Female; Humans; Lymphocytes; Middle Aged; Suicide, | 2000 |
Plasmapheresis in fatal overdose with verapamil.
Topics: Anti-Arrhythmia Agents; Critical Care; Drug Overdose; Fatal Outcome; Humans; Plasmapheresis; Suicide | 1999 |
Calcium and digoxin vs. calcium alone for severe verapamil toxicity.
Topics: Animals; Calcium; Calcium Channel Blockers; Chi-Square Distribution; Digoxin; Disease Models, Animal | 2000 |
Multifocal myoclonus due to verapamil overdose.
Topics: Calcium Channel Blockers; Drug Overdose; Female; Humans; Middle Aged; Myoclonus; Verapamil | 2002 |
Cardiac glycosides in the treatment of experimental overdose with calcium-blocking agents.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Calcium Gluconate; Depression, Chemical; Digox | 1992 |
Case report: sustained-release verapamil overdose causing stroke: an unusual complication.
Topics: Cerebrovascular Disorders; Delayed-Action Preparations; Drug Overdose; Female; Humans; Middle Aged; | 1992 |
Case report: fatal overdose with sustained-release verapamil.
Topics: 4-Aminopyridine; Adult; Delayed-Action Preparations; Drug Overdose; Female; Humans; Male; Verapamil | 1992 |
Verapamil overdose and severe hypocalcemia.
Topics: Adult; Arrhythmias, Cardiac; Blood Pressure; Calcium Gluconate; Drug Overdose; Humans; Hypocalcemia; | 1992 |
Refractory cardiogenic shock and complete heart block after unsuspected verapamil-SR and atenolol overdose.
Topics: Atenolol; Delayed-Action Preparations; Drug Overdose; Electrocardiography; Emergency Service, Hospit | 1991 |
Management of massive verapamil overdose.
Topics: Cardiac Pacing, Artificial; Combined Modality Therapy; Drug Overdose; Gastric Lavage; Humans; Male; | 1991 |
Effects of calcium channel blocker overdose-induced toxicity in the conscious dog.
Topics: Animals; Coronary Circulation; Diltiazem; Dogs; Drug Overdose; Female; Hemodynamics; Infusions, Intr | 1991 |
Delayed onset of cardiac arrhythmias from sustained-release verapamil.
Topics: Adult; Delayed-Action Preparations; Drug Overdose; Heart Block; Humans; Hypotension; Male; Verapamil | 1991 |
Verapamil overdose.
Topics: Adult; Drug Overdose; Female; Humans; Verapamil | 1991 |
Fatal verapamil toxicity and hypokalemia.
Topics: Adult; Drug Overdose; Hemodynamics; Humans; Hypokalemia; Male; Suicide; Verapamil | 1991 |
Overdose of sustained release verapamil.
Topics: Delayed-Action Preparations; Drug Overdose; Heart Arrest; Humans; Male; Middle Aged; Verapamil | 1990 |