verapamil has been researched along with Diathesis in 9 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was focused to characterize the effects of intrahippocampal application of R-verapamil, a P-glycoprotein blocker, and High Frequency Electrical Stimulation (HFS) at 130 Hz, on seizure susceptibility and extracellular concentrations of glutamate and γ-aminobutyric acid (GABA) in hippocampus of kindled rats with drug-resistant seizures." | 7.77 | Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures. ( Luna-Munguia, H; Orozco-Suarez, S; Rocha, L, 2011) |
| "This study has been designed to investigate the immunogenetic susceptibility of Cyclosporine-A (CsA) immunosuppressed renal transplant patients to development of gingival overgrowth, and the amplifying effect of calcium channel blockers on the severity of this clinical entity." | 7.69 | Evaluation of the frequency of HLA determinants in patients with gingival overgrowth induced by cyclosporine-A. ( Aydin, AE; Aygün, S; Carin, M; Cebeci, I; Firatli, E; Güç, U; Kantarci, A; Tanyeri, H; Tuncer, O, 1996) |
| "To clarify mechanisms underlying an enhanced susceptibility to cardiac rhythm disturbances in hypertension and myocardial hypertrophy, we evaluated the vulnerability to histamine-induced arrhythmias of isolated left ventricles from spontaneously hypertensive rats (SHR) and age-matched controls (Wistar-Kyoto rats, WKY)." | 7.68 | Enhanced susceptibility to histamine-induced cardiac arrhythmias in spontaneously hypertensive rats. ( Bassett, AL; Cameron, JS; Katz, D; Shin, GS; Swigart, CR, 1990) |
| "Verapamil HCl was chronically administered to inbred Dahl S/JR and R/JR rats maintained on a diet containing 8." | 5.27 | Calcium channel blockade with verapamil. Effects on blood pressure, renal, and myocardial adrenergic, cholinergic, and calcium channel receptors in inbred Dahl hypertension-sensitive (S/JR) and hypertension-resistant (R/JR) rats. ( Juno, CJ; McCaughran, JA, 1988) |
| "The present study was focused to characterize the effects of intrahippocampal application of R-verapamil, a P-glycoprotein blocker, and High Frequency Electrical Stimulation (HFS) at 130 Hz, on seizure susceptibility and extracellular concentrations of glutamate and γ-aminobutyric acid (GABA) in hippocampus of kindled rats with drug-resistant seizures." | 3.77 | Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures. ( Luna-Munguia, H; Orozco-Suarez, S; Rocha, L, 2011) |
| "This study has been designed to investigate the immunogenetic susceptibility of Cyclosporine-A (CsA) immunosuppressed renal transplant patients to development of gingival overgrowth, and the amplifying effect of calcium channel blockers on the severity of this clinical entity." | 3.69 | Evaluation of the frequency of HLA determinants in patients with gingival overgrowth induced by cyclosporine-A. ( Aydin, AE; Aygün, S; Carin, M; Cebeci, I; Firatli, E; Güç, U; Kantarci, A; Tanyeri, H; Tuncer, O, 1996) |
| " The effects of Ro 40-5967 on the susceptibility to ventricular fibrillation were investigated and compared to diltiazem." | 3.68 | Ro 40-5967, a novel calcium channel antagonist, protects against ventricular fibrillation. ( Billman, GE, 1992) |
| "To clarify mechanisms underlying an enhanced susceptibility to cardiac rhythm disturbances in hypertension and myocardial hypertrophy, we evaluated the vulnerability to histamine-induced arrhythmias of isolated left ventricles from spontaneously hypertensive rats (SHR) and age-matched controls (Wistar-Kyoto rats, WKY)." | 3.68 | Enhanced susceptibility to histamine-induced cardiac arrhythmias in spontaneously hypertensive rats. ( Bassett, AL; Cameron, JS; Katz, D; Shin, GS; Swigart, CR, 1990) |
| "Verapamil HCl was chronically administered to inbred Dahl S/JR and R/JR rats maintained on a diet containing 8." | 1.27 | Calcium channel blockade with verapamil. Effects on blood pressure, renal, and myocardial adrenergic, cholinergic, and calcium channel receptors in inbred Dahl hypertension-sensitive (S/JR) and hypertension-resistant (R/JR) rats. ( Juno, CJ; McCaughran, JA, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luna-Munguia, H | 1 |
| Orozco-Suarez, S | 1 |
| Rocha, L | 1 |
| Münter, K | 1 |
| Hergenröder, S | 1 |
| Jochims, K | 1 |
| Kirchengast, M | 1 |
| Cebeci, I | 1 |
| Kantarci, A | 1 |
| Firatli, E | 1 |
| Aygün, S | 1 |
| Tanyeri, H | 1 |
| Aydin, AE | 1 |
| Carin, M | 1 |
| Güç, U | 1 |
| Tuncer, O | 1 |
| Billman, GE | 1 |
| Cameron, JS | 1 |
| Swigart, CR | 1 |
| Shin, GS | 1 |
| Katz, D | 1 |
| Bassett, AL | 1 |
| Adnet, PJ | 2 |
| Krivosic-Horber, RM | 2 |
| Adamantidis, MM | 2 |
| Reyford, H | 1 |
| Cordonnier, C | 1 |
| Haudecoeur, G | 2 |
| Reyfort, GH | 1 |
| Dupuis, BA | 1 |
| McCaughran, JA | 1 |
| Juno, CJ | 1 |
| Foster, PS | 1 |
| Hopkinson, KC | 1 |
| Denborough, MA | 1 |
9 other studies available for verapamil and Diathesis
| Article | Year |
|---|---|
Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Drug Resistance; Electric Stimulation; Extr | 2011 |
Individual and combined effects of verapamil or trandolapril on attenuating hypertensive glomerulopathic changes in the stroke-prone rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium | 1996 |
Evaluation of the frequency of HLA determinants in patients with gingival overgrowth induced by cyclosporine-A.
Topics: Adult; Antigenic Variation; Calcium Channel Blockers; Chi-Square Distribution; Cyclosporine; Diltiaz | 1996 |
Ro 40-5967, a novel calcium channel antagonist, protects against ventricular fibrillation.
Topics: Animals; Benzimidazoles; Binding Sites; Calcium Channel Blockers; Coronary Circulation; Diltiazem; D | 1992 |
Enhanced susceptibility to histamine-induced cardiac arrhythmias in spontaneously hypertensive rats.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cimetidine; Disease Susceptibility; Drug Interacti | 1990 |
Effects of calcium-free solution, calcium antagonists, and the calcium agonist BAY K 8644 on mechanical responses of skeletal muscle from patients susceptible to malignant hyperthermia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Clinical concentrations of verapamil affect the in vitro diagnosis of susceptibility to malignant hyperpyrexia.
Topics: Caffeine; Disease Susceptibility; False Negative Reactions; Halothane; Humans; In Vitro Techniques; | 1990 |
Calcium channel blockade with verapamil. Effects on blood pressure, renal, and myocardial adrenergic, cholinergic, and calcium channel receptors in inbred Dahl hypertension-sensitive (S/JR) and hypertension-resistant (R/JR) rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Disease Susceptibility; Heart Rate; Hypertension; | 1988 |
Effect of diltiazem, verapamil and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible human skeletal muscle.
Topics: Caffeine; Dantrolene; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Mal | 1989 |