verapamil has been researched along with Death, Sudden in 22 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Heavy male Sprague-Dawley rats die of ventricular fibrillation within 2 to 3 h after isoproterenol administration." | 7.67 | Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death. ( Balazs, T; Ehrreich, SJ; el-Hage, AN; Johnson, GL, 1986) |
| "It is well documented that quinine induces reversible hearing loss and tinnitus." | 3.69 | Quinine-induced hearing loss in the guinea pig is not affected by the Ca2+ channel antagonist verapamil. ( Alván, G; Idrizbegovic, E; Jäger, W; Karlsson, KK, 1997) |
| "Sudden death was recorded by continuous ambulatory electrocardiographic (Holter) monitoring in a 62 year old man with hypertrophic cardiomyopathy and atrial fibrillation, who had been treated for four days with verapamil 360 mg orally." | 3.67 | Verapamil: a cause of sudden death in a patient with hypertrophic cardiomyopathy. ( Danchin, N; Perrot, B; Terrier de la Chaise, A, 1984) |
| "Heavy male Sprague-Dawley rats die of ventricular fibrillation within 2 to 3 h after isoproterenol administration." | 3.67 | Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death. ( Balazs, T; Ehrreich, SJ; el-Hage, AN; Johnson, GL, 1986) |
| "The efficacy of verapamil and lidocaine for treating ischemia-induced arrhythmias was determined in a conscious canine model with a previous myocardial infarction remote from the ischemic area." | 3.67 | Effects of verapamil and lidocaine in a canine model of sudden coronary death. ( Hoffman, BF; Legenza, M; Southworth, SR; Temesy-Armos, PN, 1985) |
| "Many sudden deaths are presumed to be due to an arrhythmia, but the drugs best known for antiarrhythmic activity, the local anesthetic agents, have not been suitable prophylactic agents because of their toxicities and other undesirable pharmacologic characteristics." | 2.65 | Selection of an antiarrhythmic drug for a sudden-death-prevention trial. ( Duff, HJ; Oates, JA; Roden, DM; Woosley, RL, 1982) |
| "Their value in ventricular arrhythmias is uncertain but they are unlikely to be effective except in those complicating coronary artery spasms." | 2.36 | Calcium antagonists. Clinical use in the treatment of arrhythmias. ( Baky, SH; Nademanee, K; Singh, BN, 1983) |
| " If side effects intervene that may cause continued therapy to be intolerable, changing the antiarrhythmic agent, as opposed to decreasing the dosage to an ineffective range, may be appropriate." | 1.27 | New directions in antiarrhythmic drug therapy. ( Somberg, JC, 1984) |
| "The mechanisms underlying the cause of sudden death have not been clearly elucidated." | 1.27 | [Arrhythmias in hypertrophic cardiomyopathy. Significance and therapeutic consequences]. ( Kleinebenne, A; McKenna, WJ, 1985) |
| "The treatment of hypertrophic cardiomyopathy is first and foremost symptomatic, its aim being to counteract dyspnea, angina pectoris, syncopes and lipothymias, palpitations." | 1.27 | [Treatment of hypertrophic cardiomyopathy]. ( Bouhour, JB; Lefèvre, M; Letard, G, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (86.36) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Somberg, JC | 1 |
| Woosley, RL | 1 |
| Roden, DM | 1 |
| Duff, HJ | 1 |
| Oates, JA | 1 |
| Okamatsu, S | 1 |
| Peck, RC | 1 |
| Lefer, AM | 1 |
| Clusin, WT | 1 |
| Bristow, MR | 1 |
| Karagueuzian, HS | 1 |
| Katzung, BG | 1 |
| Schroeder, JS | 1 |
| Zipes, DP | 1 |
| Gilmour, RF | 1 |
| Singh, BN | 2 |
| Nademanee, K | 1 |
| Baky, SH | 1 |
| Perrot, B | 1 |
| Danchin, N | 1 |
| Terrier de la Chaise, A | 1 |
| McKenna, WJ | 2 |
| Goodwin, JF | 1 |
| Waters, DD | 1 |
| Szlachcic, J | 1 |
| Miller, D | 1 |
| Theroux, P | 1 |
| Epstein, SE | 1 |
| Rosing, DR | 1 |
| Jäger, W | 1 |
| Idrizbegovic, E | 1 |
| Karlsson, KK | 1 |
| Alván, G | 1 |
| Citone, C | 1 |
| Romei, E | 1 |
| Dini, P | 1 |
| Milazzotto, F | 1 |
| Masini, V | 1 |
| Fazzini, P | 1 |
| Marchi, F | 1 |
| Pucci, P | 1 |
| Pelliccia, F | 1 |
| Cianfrocca, C | 1 |
| Romeo, F | 1 |
| Reale, A | 1 |
| Billman, GE | 1 |
| Kleinebenne, A | 1 |
| Bouhour, JB | 1 |
| Lefèvre, M | 1 |
| Letard, G | 1 |
| Jain, A | 1 |
| Homan, J | 1 |
| Symes, J | 1 |
| Jothy, S | 1 |
| Yunge, L | 1 |
| Huttner, I | 1 |
| Sniderman, A | 1 |
| Johnson, GL | 1 |
| Ehrreich, SJ | 1 |
| el-Hage, AN | 1 |
| Balazs, T | 1 |
| Temesy-Armos, PN | 1 |
| Legenza, M | 1 |
| Southworth, SR | 1 |
| Hoffman, BF | 1 |
3 reviews available for verapamil and Death, Sudden
| Article | Year |
|---|---|
Calcium antagonists and their potential role in the prevention of sudden coronary death.
Topics: Action Potentials; Animals; Atrial Fibrillation; Atrial Flutter; Atrioventricular Node; Calcium Chan | 1982 |
Calcium antagonists. Clinical use in the treatment of arrhythmias.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Calcium Channel Blockers; Death, | 1983 |
The natural history of hypertrophic cardiomyopathy.
Topics: Amiodarone; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Death, Sudden; Humans; Nifedipine; P | 1981 |
2 trials available for verapamil and Death, Sudden
| Article | Year |
|---|---|
Selection of an antiarrhythmic drug for a sudden-death-prevention trial.
Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneac | 1982 |
Secondary prevention of death and reinfarction with verapamil after an acute myocardial infarction. The Danish Study Group on Verapamil in Myocardial Infarction.
Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Coronary Disease; Death, Sudden; Denmark; Double-Bl | 1990 |
17 other studies available for verapamil and Death, Sudden
| Article | Year |
|---|---|
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benz | 1984 |
Effect of calcium channel blockers on arachidonate-induced sudden death in rabbits.
Topics: Animals; Arachidonic Acids; Calcium Channel Blockers; Death, Sudden; Ion Channels; Liver; Lysosomes; | 1981 |
Do calcium-dependent ionic currents mediate ischemic ventricular fibrillation?
Topics: Animals; Calcium; Coronary Circulation; Coronary Disease; Death, Sudden; Diltiazem; Heart Conduction | 1982 |
Verapamil: a cause of sudden death in a patient with hypertrophic cardiomyopathy.
Topics: Atrial Fibrillation; Cardiomyopathy, Hypertrophic; Death, Sudden; Electrocardiography; Heart Block; | 1984 |
Clinical characteristics of patients with variant angina complicated by myocardial infarction or death within 1 month.
Topics: Adult; Angina Pectoris, Variant; Coronary Disease; Coronary Vasospasm; Death, Sudden; Diltiazem; Ele | 1982 |
Verapamil: its potential for causing serious complications in patients with hypertrophic cardiomyopathy.
Topics: Arrhythmias, Cardiac; Blood Pressure; Cardiomyopathy, Hypertrophic; Death, Sudden; Depression, Chemi | 1981 |
Quinine-induced hearing loss in the guinea pig is not affected by the Ca2+ channel antagonist verapamil.
Topics: Animals; Auditory Threshold; Calcium Channel Blockers; Death, Sudden; Disease Models, Animal; Drug I | 1997 |
[Obstructive hypertrophic cardiomyopathy: excito-conduction disturbances and sudden death (author's transl)].
Topics: Adult; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Death, Sudden; Electrocardiography; Femal | 1977 |
Verapamil and sudden death.
Topics: Arrhythmias, Cardiac; Death, Sudden; Humans; Injections, Intravenous; Myocardial Infarction; Ventric | 1978 |
Hypertrophic cardiomyopathy: long-term effects of propranolol versus verapamil in preventing sudden death in "low-risk" patients.
Topics: Adult; Cardiomyopathy, Hypertrophic; Death, Sudden; Follow-Up Studies; Humans; Prognosis; Propranolo | 1990 |
Effect of calcium channel antagonists on susceptibility to sudden cardiac death: protection from ventricular fibrillation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
[Arrhythmias in hypertrophic cardiomyopathy. Significance and therapeutic consequences].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Pr | 1985 |
[Treatment of hypertrophic cardiomyopathy].
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Death, Sudden; Echo | 1985 |
Brief periods of myocardial ischemia followed by reperfusion: a model in the dog of sudden cardiac death in humans.
Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Death, Sudden; Disease Mode | 1987 |
Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death.
Topics: Animals; Anti-Arrhythmia Agents; Body Weight; Bretylium Tosylate; Death, Sudden; Disease Models, Ani | 1986 |
Effects of verapamil and lidocaine in a canine model of sudden coronary death.
Topics: Animals; Arrhythmias, Cardiac; Death, Sudden; Dogs; Female; Heart Conduction System; Heart Rate; Lid | 1985 |
Mortality in ischaemic heart disease: a biased view point.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Artery Bypass; Coronary Care Units; Coronary | 1974 |