verapamil has been researched along with Cystic Fibrosis in 3 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Epithelial cells were isolated from human nasal polyps, cultured for 5-7 days, and used to test the effect of anthracene 9-carboxylate (9-AC), known to inhibit Cl- conductance across the epithelial membrane, on the incorporation and desaturation of [1-14C]linoleic acid (C18:2,n-6) in experiments of up to 4 h duration." | 3.68 | The chloride channel blocker anthracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells. ( Brown, NE; Clandinin, MT; Kang, JX; Labrecque, PA; Man, SF, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wooten, MW | 1 |
| Rudick, MJ | 1 |
| Rudick, VL | 1 |
| Kramer, RI | 1 |
| Kang, JX | 1 |
| Man, SF | 1 |
| Brown, NE | 1 |
| Labrecque, PA | 1 |
| Clandinin, MT | 1 |
| Harris, RA | 1 |
| Baimbridge, KG | 1 |
| Bridges, MA | 1 |
| Phillips, JE | 1 |
3 other studies available for verapamil and Cystic Fibrosis
| Article | Year |
|---|---|
Effects of cystic fibrosis serum on calcium influx and secretion using isolated tracheal epithelial cells.
Topics: Adolescent; Adult; Calcimycin; Calcium; Calcium Radioisotopes; Cells, Cultured; Child; Child, Presch | 1984 |
The chloride channel blocker anthracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells.
Topics: Amiloride; Anthracenes; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Electric Con | 1992 |
Effects of various secretagogues on [Ca2+]i in cultured human nasal epithelial cells.
Topics: Bradykinin; Calcium; Cells, Cultured; Cystic Fibrosis; Dinoprostone; Dose-Response Relationship, Dru | 1991 |