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verapamil and Cystic Fibrosis

verapamil has been researched along with Cystic Fibrosis in 3 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
" Epithelial cells were isolated from human nasal polyps, cultured for 5-7 days, and used to test the effect of anthracene 9-carboxylate (9-AC), known to inhibit Cl- conductance across the epithelial membrane, on the incorporation and desaturation of [1-14C]linoleic acid (C18:2,n-6) in experiments of up to 4 h duration."3.68The chloride channel blocker anthracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells. ( Brown, NE; Clandinin, MT; Kang, JX; Labrecque, PA; Man, SF, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wooten, MW1
Rudick, MJ1
Rudick, VL1
Kramer, RI1
Kang, JX1
Man, SF1
Brown, NE1
Labrecque, PA1
Clandinin, MT1
Harris, RA1
Baimbridge, KG1
Bridges, MA1
Phillips, JE1

Other Studies

3 other studies available for verapamil and Cystic Fibrosis

ArticleYear
Effects of cystic fibrosis serum on calcium influx and secretion using isolated tracheal epithelial cells.
    Journal of cellular physiology, 1984, Volume: 121, Issue:3

    Topics: Adolescent; Adult; Calcimycin; Calcium; Calcium Radioisotopes; Cells, Cultured; Child; Child, Presch

1984
The chloride channel blocker anthracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells.
    The Biochemical journal, 1992, Aug-01, Volume: 285 ( Pt 3)

    Topics: Amiloride; Anthracenes; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Electric Con

1992
Effects of various secretagogues on [Ca2+]i in cultured human nasal epithelial cells.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:8

    Topics: Bradykinin; Calcium; Cells, Cultured; Cystic Fibrosis; Dinoprostone; Dose-Response Relationship, Dru

1991