verapamil has been researched along with Coronary Disease in 600 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In INternational VErapamil-trandolapril STudy, 22,576 CAD patients with hypertension (mean age 66 years) were randomized to verapamil-SR or atenolol-based strategies and followed for 2." | 9.14 | Pulse pressure and risk of cardiovascular outcomes in patients with hypertension and coronary artery disease: an INternational VErapamil SR-trandolapril STudy (INVEST) analysis. ( Bangalore, S; Champion, A; Franklin, SS; Mancia, G; Messerli, FH; Pepine, CJ, 2009) |
| "To evaluate the effects of Verapamil and Metoprolol on improving heart rate variability(HRV) in patients with coronary heart disease (CHD)." | 9.12 | [Effects of Verapamil and Metoprolol on heart rate variability in patients with coronary heart disease]. ( Lu, XN; Sun, NL; Zhang, Q, 2007) |
| "A total of 27,000 CAD patients with hypertension will be randomized at 1,500 primary care sites to receive either a calcium antagonist-based (verapamil) or beta-blocker/diuretic-based (atenolol/hydrochlorothiazide) antihypertensive care strategy." | 9.08 | Rationale and design of the International Verapamil SR/Trandolapril Study (INVEST): an Internet-based randomized trial in coronary artery disease patients with hypertension. ( Conlon, M; Cooper-DeHoff, R; Handberg-Thurmond, E; Marks, RG; Pepine, CJ; Volkers, P; Zellig, P, 1998) |
| "DAVIT-II is a double-blind, randomized, multicentre, placebo-controlled study of long-term treatment with verapamil 360 mg per day administered to patients who have suffered an acute myocardial infarction (AMI)." | 9.07 | Prevalence of transient myocardial ischaemia during the first year after a myocardial infarction. Effect of treatment with verapamil. The Danish Study Group on Verapamil in Myocardial Infarction. ( Hansen, JF; Holländer, NH; Rasmussen, V; Vaage-Nilsen, M, 1992) |
| "This article is a review of presented subsets of the Danish Verapamil Infarction Trial II (DAVIT II) regarding the effect of verapamil on postinfarction ischemia, ventricular arrhythmias, and heart rate (HR), and the prognostic implications of these findings." | 9.07 | Effect of verapamil on ischemia and ventricular arrhythmias after an acute myocardial infarction: prognostic implications. The Danish Verapamil Infarction Trial II Study Group. ( Bjergaard, OP; Hagerup, L; Hansen, JF; Holländer, NH; Mellemgaard, K; Nielsen, I; Rasmussen, V; Sigurd, B; Sørensen, MB; Vaage-Nilsen, M, 1991) |
| "The effect of verapamil on death and reinfarction in patients with and without exercise-induced myocardial ischemia after acute myocardial infarction was studied in a double-blind, placebo-controlled multicenter study." | 9.07 | The effect of verapamil on major events in patients with exercise-induced ischemia recovering from acute myocardial infarction: a review. The Danish Study Group on Verapamil in Myocardial Infarction. ( Jespersen, CM, 1991) |
| "We evaluated the effects of intravenous verapamil, a calcium antagonist, on hemodynamics and regional left ventricular (LV) performance in patients with acute myocardial infarction (AMI)." | 9.05 | Effects of verapamil in patients with acute myocardial infarction: hemodynamics and function of normal and ischemic left ventricular myocardium. ( Heikkilä, J; Nieminen, MS, 1984) |
| "The effectiveness of verapamil in the management of patients with unstable angina pectoris associated with obstructive coronary artery disease was evaluated in 2 double-blind placebo-controlled randomized clinical trials." | 9.05 | Verapamil therapy for unstable angina pectoris: review of double-blind placebo-controlled randomized clinical trials. ( Conti, CR; Mehta, J, 1982) |
| "Because of recurrent chest pain, 17 patients with documented spasm in coronary arteries without severe atherosclerotic obstructions were treated with verapamil in an open trial, using doses of 120 mg/day to 480 mg/day (mean, 240 mg/day)." | 9.05 | Coronary spasm management with verapamil (Isoptin). ( Freedman, B; Kelly, DT; Richmond, DR, 1980) |
| "To determine if the prophylactic administration of oral verapamil is effective in reducing the incidence of supraventricular tachycardia after myocardial revascularization, 141 patients were entered into a double-blind randomized trial." | 9.05 | Oral verapamil for prophylaxis of supraventricular tachycardia after myocardial revascularization. A randomized trial. ( Ivey, TD; Kruse, AP; Misbach, GA; Williams, DB, 1985) |
| "After 21 days of rosiglitazone therapy, hepatic failure developed." | 7.70 | Hepatic failure in a patient taking rosiglitazone. ( Diamond, RH; Forman, LM; Simmons, DA, 2000) |
| "Echocardiography was performed on 21 patients (6 women, 15 men; mean age 52 [40-68] years) with coronary heart disease (at least 75% stenosis), before and after taking 80 or 120 mg verapamil, to test the drug's acute effect on left-ventricular (LV) relaxation and filling." | 7.68 | [The effect of verapamil on left ventricular diastolic function in coronary heart disease]. ( Eichstädt, H; Hochrein, H; Möckel, M; Müller, R; Piske, G; Störk, T, 1992) |
| "We compared the effects of verapamil to high dose procainamide on the rate of inducible and spontaneously occurring ventricular tachycardia (VT) in 10 patients." | 7.67 | Verapamil in ventricular tachycardia. ( Gotsman, MS; Hasin, Y; Kriwisky, M, 1984) |
| "The actions of intravenous verapamil against arrhythmias induced by occlusion of a coronary artery were investigated in conscious rats." | 7.67 | Antiarrhythmic actions of verapamil against ischaemic arrhythmias in the rat. ( Curtis, MJ; MacLeod, BA; Walker, MJ, 1984) |
| "Efficacy and tolerance of gallopamil (Procorum) were investigated over a period of 1 year under practice conditions in a total of 455 patients (254 male, 201 female), aged 62 years (male) and 66 (female) on an average, with electrocardiographically confirmed coronary heart disease." | 7.67 | [Multicenter long-term study of gallopamil in patients with coronary heart disease]. ( Schiemann, J; Sućić, M, 1984) |
| "The antiarrhythmic activity of the calcium entry blockers, verapamil, nifedipine and prenylamine, was assessed against arrhythmias occurring during 20 min of acute occlusion, or upon rapid reperfusion of the left anterior descending coronary artery (LAD) in anesthetized pigs." | 7.67 | Acute coronary artery occlusion-reperfusion arrhythmias in pigs: antiarrhythmic and antifibrillatory evaluation of verapamil, nifedipine, prenylamine and propranolol. ( Bergey, JL; McCallum, JD; Nocella, K; Wendt, RL, 1984) |
| "In isolated heart preparations, dl-verapamil inhibits the increased vulnerability to ventricular fibrillation and reduces myocardial tissue levels of cyclic 3'5'-adenosine monophosphate (cyclic AMP), a proposed arrhythmogenic agent." | 7.67 | The influence of verapamil and its isomers on vulnerability to ventricular fibrillation during acute myocardial ischemia and adrenergic stimulation in isolated rat heart. ( Higginson, L; Opie, LH; Thandroyen, FJ, 1986) |
| "Recently, this laboratory has demonstrated an enhanced susceptibility toward the development of lethal ventricular arrhythmias occurring in response to acute posterolateral ischemia in dogs with previous anterior myocardial infarction in the presence of therapeutic serum concentrations of digoxin." | 7.67 | Effect of digoxin on the extent of injury and the severity of arrhythmias during acute myocardial ischemia and infarction in the dog. ( Lucchesi, BR; Lynch, JJ, 1988) |
| " The efficacy of magnesium sulfate for prevention of ventricular fibrillation was compared with that of the calcium blocker verapamil and other antiarrhythmic drugs in 54 open-chested anesthetized dogs during a 3-h ligation of the circumflex coronary artery." | 7.67 | Ventricular fibrillation in acute experimental myocardial ischemia: protection by magnesium sulfate. ( Barros, LF; Chagas, AC; Da-Luz, PL; Pileggi, F; Silveira, MC, 1988) |
| " A long-term, open clinical trial of verapamil therapy was conducted in ninety-three patients with coronary artery disease, selected on the basis of having stable angina pectoris and of being unsuitable for treatment with beta-adrenoceptor blocking drugs." | 7.66 | Verapamil in the long-term treatment of angina pectoris. ( Raftos, J, 1982) |
| "The effects of verapamil on vulnerability to ventricular fibrillation were studied in 55 chloralose-anaesthetised dogs." | 7.66 | Protective effect of verapamil on vulnerability to ventricular fibrillation during myocardial ischaemia and reperfusion. ( Brooks, WW; Lown, B; Verrier, RL, 1980) |
| "The effect of intravenous verapamil on the termination of supraventricular tachycardia (SVT) was studied by continuous electrocardiographic monitoring of 27 episodes of SVT." | 7.66 | Electrocardiographic observations on the termination of supraventricular tachycardia by verapamil. ( Feigl, D; Ravid, M, 1979) |
| "The effect of verapamil (Isoptin) on coronary hemodynamics was studied in 18 patients with coronary heart disease." | 7.66 | Effect of verapamil on coronary hemodynamics in patients with coronary heart disease. ( Simonsen, S, 1978) |
| " The effect of the sarcolemmal calcium flux inhibitor, verapamil, on myocardial necrosis was studied in dogs subjected to temporary coronary artery occlusion." | 7.65 | Effect of the calcium antagonist verapamil on necrosis following temporary coronary artery occlusion in dogs. ( Jennings, RB; Lowe, JE; Reimer, KA, 1977) |
| "Verapamil was administered intravenously to 250 patients aged between 14 and 85, suffering from tachyarrhythmia of various type." | 7.65 | [Clinical results with verapamil in intravenous administration in the emergency therapy of cardiac arrhythmias]. ( Amoroso, A, 1975) |
| "Pretreatment with verapamil reduced the size of these subendocardial infarcts from 34 +/- 8 to 8 +/- 3% of the ischemic circumflex vascular bed at risk (identified by postmortem perfusion of the previously occluded and unoccluded arteries with different dyes)." | 5.27 | Verapamil in two reperfusion models of myocardial infarction. Temporary protection of severely ischemic myocardium without limitation of ultimate infarct size. ( Jennings, RB; Reimer, KA, 1984) |
| "Verapamil has the same anti-anginal effect during exercise as beta-adrenoceptor blockers but has the advantage of increasing rather than decreasing the cardiac output and so fatigue both at rest and exercise commonly seen with beta-adrenoceptor blockers is not found with verapamil." | 5.27 | Verapamil in angina pectoris. ( Kelly, DT, 1986) |
| "Models of ischemic and reperfusion arrhythmias were reproduced in isolated rat hearts by means of the ligation and subsequent reocclusion of the left descending coronary artery." | 5.27 | [Prevention of ischemic and reperfusion arrhythmias using the calmodulin blocker trifluoperazine]. ( Karpov, RS; Larionov, NP; Malyshev, IIu; Meerson, FZ, 1988) |
| "Reentrant ventricular arrhythmias (RVA) were analyzed in dogs 3--7 days after ligation of the anterior descending coronary artery using averaged "composite" recordings of electrical activity of reentrant pathways (RP) from the epicardial surface of the infarction zone (IZ)." | 5.26 | Reentrant ventricular arrhythmias in the late myocardial infarction period. 7. Effect of verapamil and D-600 and the role of the "slow channel". ( El-Sherif, N; Lazzara, R, 1979) |
| "In INternational VErapamil-trandolapril STudy, 22,576 CAD patients with hypertension (mean age 66 years) were randomized to verapamil-SR or atenolol-based strategies and followed for 2." | 5.14 | Pulse pressure and risk of cardiovascular outcomes in patients with hypertension and coronary artery disease: an INternational VErapamil SR-trandolapril STudy (INVEST) analysis. ( Bangalore, S; Champion, A; Franklin, SS; Mancia, G; Messerli, FH; Pepine, CJ, 2009) |
| "To evaluate the effects of Verapamil and Metoprolol on improving heart rate variability(HRV) in patients with coronary heart disease (CHD)." | 5.12 | [Effects of Verapamil and Metoprolol on heart rate variability in patients with coronary heart disease]. ( Lu, XN; Sun, NL; Zhang, Q, 2007) |
| "A total of 27,000 CAD patients with hypertension will be randomized at 1,500 primary care sites to receive either a calcium antagonist-based (verapamil) or beta-blocker/diuretic-based (atenolol/hydrochlorothiazide) antihypertensive care strategy." | 5.08 | Rationale and design of the International Verapamil SR/Trandolapril Study (INVEST): an Internet-based randomized trial in coronary artery disease patients with hypertension. ( Conlon, M; Cooper-DeHoff, R; Handberg-Thurmond, E; Marks, RG; Pepine, CJ; Volkers, P; Zellig, P, 1998) |
| "DAVIT-II is a double-blind, randomized, multicentre, placebo-controlled study of long-term treatment with verapamil 360 mg per day administered to patients who have suffered an acute myocardial infarction (AMI)." | 5.07 | Prevalence of transient myocardial ischaemia during the first year after a myocardial infarction. Effect of treatment with verapamil. The Danish Study Group on Verapamil in Myocardial Infarction. ( Hansen, JF; Holländer, NH; Rasmussen, V; Vaage-Nilsen, M, 1992) |
| "This article is a review of presented subsets of the Danish Verapamil Infarction Trial II (DAVIT II) regarding the effect of verapamil on postinfarction ischemia, ventricular arrhythmias, and heart rate (HR), and the prognostic implications of these findings." | 5.07 | Effect of verapamil on ischemia and ventricular arrhythmias after an acute myocardial infarction: prognostic implications. The Danish Verapamil Infarction Trial II Study Group. ( Bjergaard, OP; Hagerup, L; Hansen, JF; Holländer, NH; Mellemgaard, K; Nielsen, I; Rasmussen, V; Sigurd, B; Sørensen, MB; Vaage-Nilsen, M, 1991) |
| "The effect of verapamil on death and reinfarction in patients with and without exercise-induced myocardial ischemia after acute myocardial infarction was studied in a double-blind, placebo-controlled multicenter study." | 5.07 | The effect of verapamil on major events in patients with exercise-induced ischemia recovering from acute myocardial infarction: a review. The Danish Study Group on Verapamil in Myocardial Infarction. ( Jespersen, CM, 1991) |
| "In 12 male patients with angiographically confirmed coronary heart disease and stable angina the antianginal effects of 50 mg Gallopamil have been studied in comparison with 10 mg Nifedipine and placebo." | 5.05 | [Anti-angina effect of gallopamil in comparison with another calcium antagonist and a placebo]. ( Drews, H; Hopf, R; Kaltenbach, M, 1984) |
| "We evaluated the effects of intravenous verapamil, a calcium antagonist, on hemodynamics and regional left ventricular (LV) performance in patients with acute myocardial infarction (AMI)." | 5.05 | Effects of verapamil in patients with acute myocardial infarction: hemodynamics and function of normal and ischemic left ventricular myocardium. ( Heikkilä, J; Nieminen, MS, 1984) |
| "The effectiveness of verapamil in the management of patients with unstable angina pectoris associated with obstructive coronary artery disease was evaluated in 2 double-blind placebo-controlled randomized clinical trials." | 5.05 | Verapamil therapy for unstable angina pectoris: review of double-blind placebo-controlled randomized clinical trials. ( Conti, CR; Mehta, J, 1982) |
| "Because of recurrent chest pain, 17 patients with documented spasm in coronary arteries without severe atherosclerotic obstructions were treated with verapamil in an open trial, using doses of 120 mg/day to 480 mg/day (mean, 240 mg/day)." | 5.05 | Coronary spasm management with verapamil (Isoptin). ( Freedman, B; Kelly, DT; Richmond, DR, 1980) |
| "To determine if the prophylactic administration of oral verapamil is effective in reducing the incidence of supraventricular tachycardia after myocardial revascularization, 141 patients were entered into a double-blind randomized trial." | 5.05 | Oral verapamil for prophylaxis of supraventricular tachycardia after myocardial revascularization. A randomized trial. ( Ivey, TD; Kruse, AP; Misbach, GA; Williams, DB, 1985) |
| "The haemodynamic effects of nifedipine, verapamil and diltiazem were measured and compared in an open randomized parallel investigation on 44 patients with coronary heart disease and compensated myocardial function." | 5.05 | [Differential therapy with calcium antagonists. Hemodynamic studies using nifedipine, verapamil and diltiazem]. ( Hochrein, H; Lehmann, HU, 1985) |
| "Preclinical studies were designed to investigate whether the combination of verapamil and trandolapril was more potent than either drug alone for the treatment of hypertension and concomitant cardiovascular or metabolic diseases." | 4.79 | Preclinical considerations and results with the combination of verapamil and trandolapril: blood pressure reduction and beyond. ( Kirchengast, M, 1997) |
| " Although nifedipine is highly effective against vasospastic angina, its use in threatened myocardial infarction or severe unstable angina is not supported by recent studies, unless combined with a beta-blocker." | 4.77 | Calcium channel antagonists. Part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials. ( Opie, LH, 1988) |
| " In experimental animals, verapamil has been shown to reduce vulnerability to ventricular fibrillation during sympathetic stimulation and to prevent spontaneous fibrillation during both myocardial ischaemia and reperfusion." | 4.77 | Mechanisms involved in reperfusion arrhythmias. ( Hagestad, EL; Verrier, RL, 1986) |
| " Nifedipine and diltiazem are effective in the relief of angina, and verapamil is used in the treatment of supraventricular tachyarrhythmias." | 4.77 | Calcium channel blocking agents: physiologic basis of nursing intervention. ( Touloukian, JE, 1985) |
| " In chronic arterial hypertension, verapamil, and especially diltiazem seem to be superior to nifedipine." | 4.76 | Treatment of hypertension with calcium channel blockers: European data. ( Klein, WW, 1984) |
| " This hypothesis has been tested by the use of hypothermia, pretreatment with verapamil and a reduced extracellular Ca2+ to modify the events precipitated by an ischemic episode." | 4.76 | The role of calcium in the ischemic myocardium. ( Nayler, WG, 1981) |
| "To understand the effects of single- and multiple-drug combinations for hypertension on the risk of adverse clinical outcomes, the authors analyzed data from the International Verapamil SR/Trandolapril Study (INVEST)." | 3.73 | A drug dose model for predicting clinical outcomes in hypertensive coronary disease patients. ( Cooper-DeHoff, R; Elliott, WJ; Hewkin, AC; Kupfer, S; Pepine, CJ, 2005) |
| " A verapamil SR strategy is an alternative to an atenolol strategy for the treatment of Hispanic patients with hypertension and CAD and can reduce the risk of new-onset diabetes." | 3.73 | Blood pressure control and cardiovascular outcomes in high-risk Hispanic patients--findings from the International Verapamil SR/Trandolapril Study (INVEST). ( Aranda, JM; Cangiano, JL; Conti, CR; Cooper-DeHoff, RM; Garcia-Barreto, D; Gaxiola, E; Hewkin, A; Pepine, CJ, 2006) |
| "Population pharmacokinetic analyses were performed on data from 186 patients with hypertension, coronary artery disease, or supraventricular arrhythmias who were receiving long-term sustained-release oral racemic verapamil (Covera SR in 105 patients, Calan SR in 67 patients, and other formulations in 14 patients; mean +/- SD dose, 280 +/- 139 mg) for clinical care or as a part of phase III efficacy studies." | 3.72 | Population analyses of sustained-release verapamil in patients: effects of sex, race, and smoking. ( Gupta, SK; Kang, D; Krecic-Shepard, ME; Modi, NB; Schwartz, JB; Verotta, D, 2003) |
| "After 21 days of rosiglitazone therapy, hepatic failure developed." | 3.70 | Hepatic failure in a patient taking rosiglitazone. ( Diamond, RH; Forman, LM; Simmons, DA, 2000) |
| "Echocardiography was performed on 21 patients (6 women, 15 men; mean age 52 [40-68] years) with coronary heart disease (at least 75% stenosis), before and after taking 80 or 120 mg verapamil, to test the drug's acute effect on left-ventricular (LV) relaxation and filling." | 3.68 | [The effect of verapamil on left ventricular diastolic function in coronary heart disease]. ( Eichstädt, H; Hochrein, H; Möckel, M; Müller, R; Piske, G; Störk, T, 1992) |
| "We compared the effects of verapamil to high dose procainamide on the rate of inducible and spontaneously occurring ventricular tachycardia (VT) in 10 patients." | 3.67 | Verapamil in ventricular tachycardia. ( Gotsman, MS; Hasin, Y; Kriwisky, M, 1984) |
| "The actions of intravenous verapamil against arrhythmias induced by occlusion of a coronary artery were investigated in conscious rats." | 3.67 | Antiarrhythmic actions of verapamil against ischaemic arrhythmias in the rat. ( Curtis, MJ; MacLeod, BA; Walker, MJ, 1984) |
| "Efficacy and tolerance of gallopamil (Procorum) were investigated over a period of 1 year under practice conditions in a total of 455 patients (254 male, 201 female), aged 62 years (male) and 66 (female) on an average, with electrocardiographically confirmed coronary heart disease." | 3.67 | [Multicenter long-term study of gallopamil in patients with coronary heart disease]. ( Schiemann, J; Sućić, M, 1984) |
| "The antiarrhythmic activity of the calcium entry blockers, verapamil, nifedipine and prenylamine, was assessed against arrhythmias occurring during 20 min of acute occlusion, or upon rapid reperfusion of the left anterior descending coronary artery (LAD) in anesthetized pigs." | 3.67 | Acute coronary artery occlusion-reperfusion arrhythmias in pigs: antiarrhythmic and antifibrillatory evaluation of verapamil, nifedipine, prenylamine and propranolol. ( Bergey, JL; McCallum, JD; Nocella, K; Wendt, RL, 1984) |
| "In isolated heart preparations, dl-verapamil inhibits the increased vulnerability to ventricular fibrillation and reduces myocardial tissue levels of cyclic 3'5'-adenosine monophosphate (cyclic AMP), a proposed arrhythmogenic agent." | 3.67 | The influence of verapamil and its isomers on vulnerability to ventricular fibrillation during acute myocardial ischemia and adrenergic stimulation in isolated rat heart. ( Higginson, L; Opie, LH; Thandroyen, FJ, 1986) |
| "Recently, this laboratory has demonstrated an enhanced susceptibility toward the development of lethal ventricular arrhythmias occurring in response to acute posterolateral ischemia in dogs with previous anterior myocardial infarction in the presence of therapeutic serum concentrations of digoxin." | 3.67 | Effect of digoxin on the extent of injury and the severity of arrhythmias during acute myocardial ischemia and infarction in the dog. ( Lucchesi, BR; Lynch, JJ, 1988) |
| "The effects of three calcium antagonists (diltiazem, verapamil, and nifedipine) on reperfusion-induced arrhythmias were compared in a conscious rat preparation with coronary artery occlusion and implanted electrocardiogram limb electrodes." | 3.67 | Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS; Mitani, A, 1989) |
| " The efficacy of magnesium sulfate for prevention of ventricular fibrillation was compared with that of the calcium blocker verapamil and other antiarrhythmic drugs in 54 open-chested anesthetized dogs during a 3-h ligation of the circumflex coronary artery." | 3.67 | Ventricular fibrillation in acute experimental myocardial ischemia: protection by magnesium sulfate. ( Barros, LF; Chagas, AC; Da-Luz, PL; Pileggi, F; Silveira, MC, 1988) |
| "The effect of an antioxidant dibunol and calcium antagonist verapamil on postperfusion release of myoglobin (Mb) and MB-creatine kinase (MB-CK) has been assessed in 30 dogs with experimental coronary occlusive myocardial infarction." | 3.67 | [Effect of dibunol and isoptin on the creatine kinase and myoglobin content of the blood serum in dogs undergoing postischemic coronary reperfusion]. ( Avilova, OA; Berestov, AA; Golikov, AP; Konorev, EA; Polumiskov, VIu, 1987) |
| " The present study was designed to simulate the clinical situation of reocclusion and determine whether verapamil might be effective in reducing myocardial necrosis and preserving high energy phosphates in this setting." | 3.67 | Effect of verapamil on infarct size in dogs subjected to coronary artery occlusion with transient reperfusion. ( Alker, KJ; Braunwald, E; Campbell, CA; Kloner, RA, 1986) |
| "Three patients with ischaemic heart disease developed profound cardiac failure, hypotension and bradycardia during combined therapy with verapamil and beta-adrenergic blocking drugs." | 3.66 | Adverse interaction between beta-adrenergic blocking drugs and verapamil--report of three cases. ( Anderson, ST; Federman, J; Harper, RW; Laufer, E; Pitt, A; Wayne, VS, 1982) |
| " A long-term, open clinical trial of verapamil therapy was conducted in ninety-three patients with coronary artery disease, selected on the basis of having stable angina pectoris and of being unsuitable for treatment with beta-adrenoceptor blocking drugs." | 3.66 | Verapamil in the long-term treatment of angina pectoris. ( Raftos, J, 1982) |
| "Clinical experience with calcium antagonists in congestive heart failure has, to date, been mainly restricted to the use of nifedipine but there is either no or only a limited extent of information available on diltiazem and verapamil." | 3.66 | Calcium antagonists in heart failure. ( Camerini, F; Klugmann, S; Salvi, A, 1983) |
| " We administered 40-, 80- and 120-mg doses of verapamil orally to 15 patients with angina pectoris who were receiving high doses of propranolol or metoprolol." | 3.66 | Hemodynamic consequences of combined beta-adrenergic and slow calcium channel blockade in man. ( Gorlin, R; Guererro, J; Holt, J; McAllister, RG; Medina, N; Meller, J; Packer, M; Smith, H; Todd, GD; Yushak, M, 1982) |
| "A 35-year-old man with class 2 angina pectoris was enlisted in a serial exercise test protocol to evaluate oral verapamil therapy for angina pectoris." | 3.66 | Suppression of ischemic related ventricular tachycardia by verapamil during treadmill exercise testing. ( Brodsky, SJ; Cutler, SS; Klein, MD; Weiner, DA, 1982) |
| " But when rapid control of the ventricular rate is required to arrhythmias such as atrial fibrillation, atrial flutter, or paroxysmal atrial tachycardia, a slow infusion of verapamil is the agent of choice." | 3.66 | Anti-arrhythmic agents in ischemic heart disease: supraventricular arrhythmias, digitalis toxicity and chronic stable ventricular ectopic beats. ( Opie, LH, 1982) |
| "The effects of verapamil on vulnerability to ventricular fibrillation were studied in 55 chloralose-anaesthetised dogs." | 3.66 | Protective effect of verapamil on vulnerability to ventricular fibrillation during myocardial ischaemia and reperfusion. ( Brooks, WW; Lown, B; Verrier, RL, 1980) |
| "The effect of intravenous verapamil on the termination of supraventricular tachycardia (SVT) was studied by continuous electrocardiographic monitoring of 27 episodes of SVT." | 3.66 | Electrocardiographic observations on the termination of supraventricular tachycardia by verapamil. ( Feigl, D; Ravid, M, 1979) |
| "The effect of verapamil (Isoptin) on coronary hemodynamics was studied in 18 patients with coronary heart disease." | 3.66 | Effect of verapamil on coronary hemodynamics in patients with coronary heart disease. ( Simonsen, S, 1978) |
| " The effect of the sarcolemmal calcium flux inhibitor, verapamil, on myocardial necrosis was studied in dogs subjected to temporary coronary artery occlusion." | 3.65 | Effect of the calcium antagonist verapamil on necrosis following temporary coronary artery occlusion in dogs. ( Jennings, RB; Lowe, JE; Reimer, KA, 1977) |
| "Verapamil was administered intravenously to 250 patients aged between 14 and 85, suffering from tachyarrhythmia of various type." | 3.65 | [Clinical results with verapamil in intravenous administration in the emergency therapy of cardiac arrhythmias]. ( Amoroso, A, 1975) |
| "The risk of cancer in users of verapamil was assessed in a long-term follow-up of 1,775 patients who were randomized to verapamil or matching placebo in the Danish Verapamil Infarction Trial-II in the years 1985 to 1987." | 2.69 | Verapamil and risk of cancer in patients with coronary artery disease. DAVIT Study Group. Danish Verapamil Infarction Trial. ( Hansen, JF; Sajadieh, A; Storm, HH, 1999) |
| "The chronic effect on ventricular extrasystoles of the degrees of severity mostly II-IV were investigated in the open experiment on 17 patients as well as on 3 patients with supraventricular dysrhythmias and on 30 patients with ventricular extrasystoles Lown III-IV in the single blind cross-over experiments to verapamil retard." | 2.67 | [Hemodynamic and clinical studies with Bonnecor--a new anti-arrhythmia drug]. ( Assmann, I; Kassel, P; von Knorre, G, 1990) |
| " After a stable control period, dose-response curves were constructed for each drug with hemodynamics measured 10 minutes after intravenous boluses." | 2.66 | Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease. ( Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP, 1987) |
| " Warfarin was started on the day of the procedure and the dosage was adjusted to maintain the thromboplastin international normalised ratio greater than or equal to 2." | 2.66 | Lack of effect of warfarin on the restenosis rate or on clinical outcome after balloon coronary angioplasty. ( Bayliss, J; Buller, N; Fox, K; Rickards, A; Shapiro, L; Urban, P, 1988) |
| "Verapamil has a negative inotropic action in isolated cardiac muscle." | 2.65 | Effect of verapamil on left ventricular function: a randomized, placebo-controlled study. ( Farias, MA; Frye, RL; Ritman, EL; Smith, HC; Vlietstra, RE, 1983) |
| "Ventricular arrhythmias are significantly associated with arrhythmic as well as non-arrhythmic death." | 2.39 | Anti-ischemic intervention as prognosis improvement in patients with coronary artery disease, with special focus on verapamil. ( Jespersen, CM, 1996) |
| "Verapamil has well proven efficacy in the treatment of patients with hypertension, and early studies indicated its efficacy in the treatment of coronary artery disease." | 2.39 | Verapamil: a review of its pharmacological properties and therapeutic use in coronary artery disease. ( Benfield, P; Brogden, RN, 1996) |
| "Verapamil pretreatment produced a similarly selective dilatation of larger coronary arterioles and protected against the ischaemia-induced fall in capillary red cell content." | 2.38 | Calcium antagonists and myocardial microperfusion. ( Köbler, W; Möller, P; Neumann, FJ; Parekh, N; Steinhausen, M; Tillmanns, H; Waas, W; Zimmermann, R, 1991) |
| "With verapamil there is a small tendency for a reduction in reinfarction, with nifedipine a clear worsening, and with diltiazem a reduction almost reaching statistical significance." | 2.38 | Protective effects of calcium antagonists against ischaemia and reperfusion damage. ( Ferrari, R; Visioli, O, 1991) |
| "When nifedipine was compared with isosorbide dinitrate in a randomized crossover, double-blind trial in patients with coronary artery spasm, both drugs were shown to be efficacious and neither was superior." | 2.37 | Large vessel coronary vasospasm: diagnosis, natural history and treatment. ( Conti, CR, 1985) |
| "Pretreatment with verapamil essentially ablated the phenomenon of postischemic stunning: segment shortening was restored to 115 +/- 8% of normal after 3 h of reflow (p less than 0." | 2.37 | Effect of verapamil on postischemic "stunned" myocardium: importance of the timing of treatment. ( Kloner, RA; Przyklenk, K, 1988) |
| "Pretreatment with verapamil reduced the size of these subendocardial infarcts from 34 +/- 8 to 8 +/- 3% of the ischemic circumflex vascular bed (anatomic area at risk)." | 2.37 | Effects of calcium-channel blockers on myocardial preservation during experimental acute myocardial infarction. ( Jennings, RB; Reimer, KA, 1985) |
| "Cardiogenic shock is associated with primary myocardial failure and a low-flow state." | 2.36 | Calcium entry blockers: potential applications in shock. ( Greenfield, LJ; Hess, ML, 1983) |
| "Verapamil was the first of a class of agents known as calcium entry blockers to be released for clinical use in the United States." | 2.36 | The clinical use of verapamil. ( Holmes, DR; McGoon, MD; Osborn, JE; Vlietstra, RE, 1982) |
| "Verapamil is a novel antiarrhythmic and antianginal agent which, although introduced in 1962, has only recently gained prominence not only as a significant agent in cardiovascular therapeutics but also as a powerful tool to examine the nature of some of the biophysical phenomena at the membrane of cardiac and other excitable tissues." | 2.36 | Verapamil: a review of its pharmacological properties and therapeutic use. ( Ellrodt, G; Peter, CT; Singh, BN, 1978) |
| " No adverse events resulted from rate control medication." | 1.35 | Safety and efficacy of a rate control protocol for cardiac CT. ( Roberts, WT; Timmis, AD; Timmis, JB; Wright, AR, 2009) |
| "Verapamil is a widely used Ca(2+) channel antagonist in the treatment of cardiovascular disorders including atrial arrhythmias." | 1.32 | Inhibition of ultra-rapid delayed rectifier K+ current by verapamil in human atrial myocytes. ( Chiu, SW; Gao, Z; Lau, CP; Li, GR, 2004) |
| "Verapamil was administered in a 50 micrograms/kg dose followed by 2 micrograms/kg/min infusion." | 1.30 | Calcium antagonists and prevention of ventricular fibrillation induced by transient or persistent ischemia. ( Aupetit, JF; Bui-Xuan, B; Evreux, JC; Faucon, G; Freysz, M; Timour, Q, 1997) |
| "Of 246 incident cancer cases, 129 occurred among the users (2." | 1.30 | Calcium channel blocking agents and risk of cancer in patients with coronary heart disease. Benzafibrate Infarction Prevention (BIP) Study Research Group. ( Behar, S; Boyko, V; Braun, S; Goldbourt, U; Kaplinsky, E; Laniado, S; Reicher-Reiss, H, 1998) |
| "Twenty-five VTs showed right bundle branch block morphology and 23 left bundle branch block morphology, and VT was entrained in 84 and 96%, respectively." | 1.29 | Frequency of presumed reentry with an excitable gap in sustained ventricular tachycardia unassociated with coronary artery disease. ( Aizawa, Y; Kitazawa, H; Kusano, Y; Naitoh, N; Shibata, A; Uchiyama, H; Washizuka, T, 1993) |
| "Treatment with verapamil but not with ryanodine during ischemia attenuated the increase in m-calpain activity." | 1.29 | Calpain activity alters in rat myocardial subfractions after ischemia or reperfusion. ( Kawashima, S; Yamasaki, Y; Yoshida, K, 1993) |
| " However, the long term use of these drugs has additional advantages, particularly with respect to their ability to slow Ca(++)-dependent processes involved in the formation of atherogenic lesions, partially antagonise the effects of the raised levels of circulating endothelin-1 encountered during ischaemia-induced heart failure and hypertension, and trap and immobilise oxyradicals." | 1.28 | The molecular basis for the use of calcium antagonists in ischaemic heart disease. ( Nayler, WG, 1992) |
| "Both propranolol and verapamil were slightly more active than carvedilol in inhibiting epinephrine-induced platelet aggregation, a trend consistent with the IC50 values." | 1.28 | Comparison of the effects of carvedilol, propranolol, and verapamil on in vitro platelet function in healthy volunteers. ( Betterridge, DJ; Gasser, JA, 1991) |
| "Pretreatment with verapamil extends the ischaemic time after which reperfusion results in myocardial salvage in this model of ischaemia and reperfusion." | 1.28 | Myocardial protection with verapamil during ischaemia and reperfusion: dissociation between myocardial salvage and the degree of ATP depletion during ischaemia. ( Donnelly, TJ; Parmley, WW; Sievers, R; Wolfe, CL, 1991) |
| "When treated by verapamil, coronary patients responded differently." | 1.28 | [Effects of verapamil on the functional state of the liver in ischemic heart disease]. ( Makarovskiĭ, VV; Makeeva, LG; Shafranskiĭ, IuA; Svetova, SD; Vertkina, NV; Zharov, EI, 1991) |
| " DSPM at higher dosage also lowered the normal myocardial Ca2+ content." | 1.28 | [Protective effect of 2-[p-(dimethylamino) styryl] pyridine methiodide (DSPM) on acute experimental myocardial ischemia]. ( Wang, XF; Wang, XW; Wei, Y; Zhang, KJ; Zhou, CM, 1990) |
| "Verapamil treatment of the aortic constricted hearts prevented the rise in intracellular calcium, and attenuated phosphomonoester sugar accumulation." | 1.28 | Calcium inhibition of glycolysis contributes to ischaemic injury. ( Auffermann, W; Buser, P; Parmley, WW; Wagner, S; Wikman-Coffelt, J; Wu, S, 1990) |
| "Pretreatment with anipamil induced a negative inotropic effect under normoxic conditions; reduced the rate and extent of depletion of ATP and creatine phosphate during ischemia, with an incomplete restoration of the nucleotides after reperfusion; maintained mitochondrial function and calcium homeostasis during ischemia and reperfusion; reduced the rate of CPK release; and improved the recovery of ventricular function on reperfusion." | 1.28 | Prolonged protective effect of the calcium antagonist anipamil on the ischemic reperfused rabbit myocardium: comparison with verapamil. ( Ceconi, C; Curello, S; Ferrari, R; Ghielmi, S; Raddino, R; Visioli, O, 1989) |
| "Verapamil was able to reduce postoperative HR by 3% in patients without CAD and by 13% in patients with CAD." | 1.28 | Hemodynamic benefits of verapamil after aortic reconstruction. ( Dahn, MS; Jacobs, LA; Lange, MP; Pozderac, R; Wilson, RF, 1989) |
| "4." | 1.28 | Effects of verapamil on ischaemia-induced impairment of ATP-dependent calcium extrusion in rat heart sarcolemma. ( Goddijn, MM; Haas, M; Punt, NC; van Amsterdam, FT; Zaagsma, J, 1989) |
| "Verapamil-treated dogs showed higher pH of ischemic subendocardium after 15 min ischemia (6." | 1.28 | Contrasting effects of verapamil and nifedipine on pH of ischemic myocardium in the dog. ( Aamodt, R; Epstein, SE; Goldstein, SR; Greene, R; Markle, DR; Patterson, RE; Ro, YM; Speir, E; Steadman, K, 1989) |
| "Nifedipine is a strong calcium antagonist; it blocks the excitation-contraction coupling, yet at therapeutic dosage levels it has few side effects." | 1.27 | What is preferable in unstable angina, beta-blockade or calcium-inhibition? ( Hugenholtz, PG; Serruys, PW; Simoons, ML, 1983) |
| "The reported recurrence rate is lower than comparable figures in published reports." | 1.27 | [Incidence of recurrence after successful transluminal coronary angioplasty]. ( Kaltenbach, M; Kober, G; Scherer, D; Schmidt-Moritz, A, 1983) |
| "When verapamil was present before ischemia, pressure development during early ischemia was reduced to about 50% of control." | 1.27 | Verapamil protection of ischemic isolated rabbit heart: dependence on pretreatment. ( Bersohn, MM; Shine, KI, 1983) |
| "Verapamil was administered as a 2-minute bolus (0." | 1.27 | Effects of verapamil on coronary hemodynamic function and vasomobility relative to its mechanism of antianginal action. ( Brown, BG; Chew, CY; Petersen, R; Pierce, C; Singh, BN; Wong, MM, 1983) |
| "In verapamil-treated dogs inosine and hypoxanthine levels increased to only 1." | 1.27 | Preservation of high-energy phosphates by verapamil in reperfused myocardium. ( Alker, KJ; Braunwald, E; Hale, SL; Ingwall, J; Kloner, RA; Lange, R, 1984) |
| "Pretreatment with verapamil reduced the size of these subendocardial infarcts from 34 +/- 8 to 8 +/- 3% of the ischemic circumflex vascular bed at risk (identified by postmortem perfusion of the previously occluded and unoccluded arteries with different dyes)." | 1.27 | Verapamil in two reperfusion models of myocardial infarction. Temporary protection of severely ischemic myocardium without limitation of ultimate infarct size. ( Jennings, RB; Reimer, KA, 1984) |
| "Twenty-six patients had no ventricular arrhythmias in 633 ischemic attacks; 16 patients had ventricular arrhythmias in 116/586 ischemic attacks." | 1.27 | [Characterization and therapy of ventricular arrhythmias due to transient myocardial ischemic attacks in variant angina]. ( Dini, P; Prati, PL; Rocca, P; Turitto, G; Vicari, M; Zanchi, E, 1984) |
| "As an aid to clinical therapeutic decisions, the haemodynamic dose-response effects following intravenous verapamil were evaluated in ten male patients with angiographically confirmed and stable coronary artery disease." | 1.27 | Haemodynamic dose-response effects of i.v. verapamil in coronary artery disease. ( Ahuja, RC; Hussain, M; Nelson, GI; Silke, B; Taylor, SH; Verma, SP, 1984) |
| "Verapamil was more active than nifedipine in both models." | 1.27 | Evaluation of cardiac anoxia and ischemia models in the rat using calcium antagonists. ( Jacobs, LW; Rosenberger, LB; Stanton, HC, 1984) |
| " The dose-response curve for verapamil was bell-shaped and the activity resided in the l form." | 1.27 | An inhibitory effect of verapamil and diltiazem on the release of noradrenaline from ischaemic and reperfused hearts. ( Nayler, WG; Sturrock, WJ, 1984) |
| "Verapamil was shown to be able to recover a significantly depressed actomyosin ATPase activity of the unaffected left ventricular area in experimental myocardial ischemia." | 1.27 | [Effect of verapamil on the molecular characteristics of myocardial actomyosin in experimental ischemia]. ( Dzhanpoladian, EG; Kaĭfadzhian, MA; Oganesian, SS; Samvelian, VM; Zaminian, TS, 1986) |
| "Verapamil has the same anti-anginal effect during exercise as beta-adrenoceptor blockers but has the advantage of increasing rather than decreasing the cardiac output and so fatigue both at rest and exercise commonly seen with beta-adrenoceptor blockers is not found with verapamil." | 1.27 | Verapamil in angina pectoris. ( Kelly, DT, 1986) |
| "Trimetazidine was added in the superfusion during the last hour of stabilization and maintained during the ischaemic and the reperfusion periods." | 1.27 | [Effects of trimetazidine on a model of in vitro myocardial ischemia]. ( Adamantidis, M; Challice, C; Dupuis, B; Honoré, E; Libersa, C; Rouet, E, 1986) |
| "Bepridil was more effective than verapamil in protecting against this ischaemic damage." | 1.27 | Protective effects of the calmodulin antagonist bepridil on ischaemia induced in the rat myocardium. ( Hidaka, H; Itoh, H; Kusagawa, M; Shikano, K, 1986) |
| "When verapamil was injected a dose-dependent vasodilation was observed, which began to be significant with doses higher than 250 micrograms." | 1.27 | Dose-response scrutiny of coronary vasodilation after intracoronary verapamil in man. A quantitative cineangiographic study. ( De Nes, DM; L'Abbate, A; Michelassi, C; Parodi, O; Simonetti, I; Trivella, MG, 1986) |
| "When used in conjunction with raw arrhythmia data, comprehensive drug dose ranges, and appropriate parametric statistical tests, arrhythmia scores facilitate the quantification of arrhythmias." | 1.27 | Quantification of arrhythmias using scoring systems: an examination of seven scores in an in vivo model of regional myocardial ischaemia. ( Curtis, MJ; Walker, MJ, 1988) |
| "The influence of verapamil (V) and of V combined with glucose-insulin-potassium (VG) on ischemic injured myocardium was investigated in dogs after ligation of the left anterior descending coronary artery." | 1.27 | Influence of verapamil and its combination with glucose-insulin-potassium-infusion on acute myocardial ischemia in dogs. ( Beyerdörfer, I; Buller, G; Goos, H; Graff, J; Krause, EG; Lindenau, KF; Nöhring, J; Pissarek, M, 1987) |
| "Verapamil treatment of animals subjected to ischemia was not associated with sustained elevations of left atrial pressure to values above those measured in animals receiving the vehicle." | 1.27 | Effects of intracoronary verapamil administration in a sheep model of acute myocardial ischemia and reperfusion. ( Korn, RL; Pollock, JV; Spath, JA, 1988) |
| "Models of ischemic and reperfusion arrhythmias were reproduced in isolated rat hearts by means of the ligation and subsequent reocclusion of the left descending coronary artery." | 1.27 | [Prevention of ischemic and reperfusion arrhythmias using the calmodulin blocker trifluoperazine]. ( Karpov, RS; Larionov, NP; Malyshev, IIu; Meerson, FZ, 1988) |
| "Correspondingly, ventricular arrhythmias and fibrillation were almost completely prevented by metoprolol, d-sotalol or verapamil, but increased by lidocaine." | 1.27 | Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion. ( Gülker, H; Haverkamp, W; Hindricks, G; Thale, J, 1987) |
| "In subjects with known migraine, the occurrence of chest pain may represent coronary artery spasm, and should be investigated with concurrent electrocardiographs, as these two clinical entities may be related as part of a generalised vasospastic disorder." | 1.27 | A possible relationship between migraine and coronary artery spasm. ( Wayne, VS, 1986) |
| " Verapamil alone had no protective effect on reperfused myocardium, whereas dibunol, and particularly its combination with verapamil, essentially limited the size of necrosis, reduced plasma CPK activity and animal mortality rate and maintained ultrastructural integrity of cardiomyocytes, which was accompanied by a decrease of plasma lipid peroxidation products and a stabilization of cardiomyocyte sarcolemma." | 1.27 | [Prevention of myocardial damage during reperfusion of the coronary artery in dogs using dibunol combined with verapamil]. ( Golikov, AP; Konorev, EA; Pichugin, VV; Polumiskov, VIu; Sharov, VG, 1987) |
| " Twelve patients were not receiving therapy or were receiving very low dosage therapy, including 8 with asymptomatic periods of more than 1 year." | 1.27 | Late follow-up (41 to 102 months) of medically treated patients with coronary artery spasm and minor atherosclerotic coronary obstructions. ( Alwyn, M; Freedman, SB; Kelly, DT; Richmond, DR, 1986) |
| "Anipamil has a more favourable ratio of antiarrhythmic to hypotensive effects when compared with verapamil." | 1.27 | Actions of the verapamil analogues, anipamil and ronipamil, against ischaemia-induced arrhythmias in conscious rats. ( Curtis, MJ; Walker, MJ; Yuswack, T, 1986) |
| "Pretreatment with verapamil (0." | 1.27 | Effects of verapamil on regional myocardial diastolic function in pacing-induced ischemia in dogs. ( Bourdillon, PD; Grossman, W; Paulus, WJ; Serizawa, T, 1986) |
| "(-)-Verapamil was consistently 4 times more potent than (+)-verapamil." | 1.27 | The mechanism of action of the optical enantiomers of verapamil against ischaemia-induced arrhythmias in the conscious rat. ( Curtis, MJ; Walker, MJ, 1986) |
| "Diltiazem was not significantly different from placebo." | 1.27 | Comparative effects of calcium-channel blocking agents on left ventricular function during acute ischemia in dogs with and without congestive heart failure. ( Epstein, SE; Patterson, RE; Urquhart, J, 1985) |
| "Verapamil pretreatment significantly increased oxidation of all substrates by the subsequently isolated Polytron mitochondria, but only succinate-supported respiration returned to control levels." | 1.27 | Protection of canine cardiac mitochondrial function by verapamil-cardioplegia during ischemic arrest. ( Entman, ML; Lewis, RM; McMillin-Wood, JB; Michael, LH; Yoon, SB, 1985) |
| "Verapamil has been shown to depress the contractility of ischemic myocardium." | 1.27 | Effect of verapamil on pH of ischemic canine myocardium. ( Epstein, SE; Markle, DR; McGuire, DA; Patterson, RE; Vitale, D; Watson, RM, 1985) |
| "In treated dogs, verapamil was given, 0." | 1.26 | Effect of verapamil on conduction delay produced by myocardial ischemia and reperfusion. ( Fujimoto, T; Hamamoto, H; Mandel, WJ; Peter, T, 1981) |
| "Coronary spasm is due to strong contraction of coronary vascular smooth muscle cells which is triggered by an increase of intracellular calcium ions; hyperventilation plus TRIS-buffer infusion induces coronary spasm by decreasing hydrogen ions which antagonize the action of calcium ions." | 1.26 | Pathophysiology and treatment of coronary arterial spasm. ( Yasue, H, 1980) |
| "3." | 1.26 | The cardioprotective effect of verapamil. ( Nayler, WG; Slade, AM, 1982) |
| "In the isolated rat heart, anoxia or ischemia do not induce important ventricular tachyarrhythmias (VTAs)." | 1.26 | Inhibitory effect of anoxia on reperfusion- and digitalis-induced ventricular tachyarrhythmias. ( Carbonin, P; Di Gennaro, M; Valle, R; Weisz, AM, 1981) |
| " The dosage was 3 x 80 mg/die during 4 weeks." | 1.26 | [Exertion-electrocardiographic and hemodynamic studies with oral verapamil in chronic ischemic heart disease]. ( Assmann, I; Fiehring, H; Oltmanns, G; Schwela, H, 1978) |
| "Reentrant ventricular arrhythmias (RVA) were analyzed in dogs 3--7 days after ligation of the anterior descending coronary artery using averaged "composite" recordings of electrical activity of reentrant pathways (RP) from the epicardial surface of the infarction zone (IZ)." | 1.26 | Reentrant ventricular arrhythmias in the late myocardial infarction period. 7. Effect of verapamil and D-600 and the role of the "slow channel". ( El-Sherif, N; Lazzara, R, 1979) |
| "The incidence of ventricular arrhythmias was increased by aprindine (from 1 in 11 to 8 in 11 dogs), decresed by verapamil (from 3 in 7 to 0 in 7 dogs) and was not changes by quinidine or isoproterenol." | 1.26 | Effect of drugs on conduction delay and incidence of ventricular arrhythmias induced by acute coronary occlusion in dogs. ( Elharrar, V; Gaum, WE; Zipes, DP, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 465 (77.50) | 18.7374 |
| 1990's | 108 (18.00) | 18.2507 |
| 2000's | 27 (4.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pacanowski, MA | 1 |
| Gong, Y | 1 |
| Cooper-Dehoff, RM | 2 |
| Schork, NJ | 1 |
| Shriver, MD | 1 |
| Langaee, TY | 1 |
| Pepine, CJ | 7 |
| Johnson, JA | 1 |
| Roberts, WT | 1 |
| Wright, AR | 1 |
| Timmis, JB | 1 |
| Timmis, AD | 1 |
| Bangalore, S | 1 |
| Messerli, FH | 1 |
| Franklin, SS | 1 |
| Mancia, G | 1 |
| Champion, A | 1 |
| Kullmann, S | 1 |
| Binner, P | 1 |
| Rackebrandt, K | 1 |
| Huge, A | 1 |
| Haltern, G | 1 |
| Lankisch, M | 1 |
| Füth, R | 1 |
| von Hodenberg, E | 2 |
| Bestehorn, HP | 1 |
| Scheffold, T | 2 |
| Skelding, KA | 1 |
| Goldstein, JA | 1 |
| Mehta, L | 1 |
| Pica, MC | 1 |
| O'Neill, WW | 1 |
| Sidorenko, GI | 1 |
| Ostrovskiĭ, IuP | 1 |
| Kang, D | 1 |
| Verotta, D | 1 |
| Krecic-Shepard, ME | 1 |
| Modi, NB | 1 |
| Gupta, SK | 1 |
| Schwartz, JB | 1 |
| Beltrame, JF | 1 |
| Turner, SP | 1 |
| Leslie, S | 1 |
| Horowitz, JD | 3 |
| TSCHIRDEWAHN, B | 2 |
| KLEPZIG, H | 1 |
| HOFFMANN, P | 1 |
| STRAESSLE, B | 1 |
| BURCKHARDT, D | 1 |
| FISCHER, K | 1 |
| BIEHLER, W | 1 |
| Gao, Z | 1 |
| Lau, CP | 1 |
| Chiu, SW | 1 |
| Li, GR | 1 |
| Reffelmann, T | 1 |
| Kloner, RA | 6 |
| Liebson, PR | 1 |
| Conti, CR | 6 |
| Gurevich, MA | 1 |
| Elliott, WJ | 1 |
| Hewkin, AC | 1 |
| Kupfer, S | 1 |
| Cooper-DeHoff, R | 2 |
| Formica, F | 1 |
| Ferro, O | 1 |
| Brustia, M | 1 |
| Corti, F | 1 |
| Colagrande, L | 1 |
| Bosisio, E | 1 |
| Paolini, G | 1 |
| Aranda, JM | 1 |
| Gaxiola, E | 1 |
| Cangiano, JL | 1 |
| Garcia-Barreto, D | 1 |
| Hewkin, A | 1 |
| Pullakhandam, NS | 1 |
| Yang, ZJ | 1 |
| Thomas, S | 1 |
| Wasenko, J | 1 |
| Iwasaki, K | 1 |
| Samukawa, M | 1 |
| Furukawa, H | 1 |
| Zhang, Q | 1 |
| Lu, XN | 1 |
| Sun, NL | 1 |
| Attaran, S | 1 |
| John, L | 1 |
| El-Gamel, A | 1 |
| Guadagno, L | 1 |
| Giannelli, G | 1 |
| Ghiara, F | 1 |
| Guadagno, P | 1 |
| Zucchelli, GP | 1 |
| Benthe, HF | 1 |
| Massie, BM | 1 |
| Hirsch, AT | 1 |
| Inouye, IK | 1 |
| Tubau, JF | 1 |
| Lehmann, HU | 3 |
| Hochrein, H | 4 |
| Geddes, JS | 1 |
| Adgey, AA | 1 |
| Pantridge, JF | 1 |
| Karlsberg, RP | 2 |
| Oesterle, SN | 1 |
| Schroeder, JS | 3 |
| Valentine, PA | 1 |
| Sutton, LD | 1 |
| Sloman, JG | 1 |
| Málek, I | 1 |
| Kolc, J | 1 |
| Málek, P | 1 |
| Wheatley, D | 1 |
| Wayne, VS | 2 |
| Harper, RW | 1 |
| Laufer, E | 1 |
| Federman, J | 1 |
| Anderson, ST | 1 |
| Pitt, A | 1 |
| Nayler, WG | 11 |
| Omura, Y | 1 |
| Hugenholtz, PG | 3 |
| Serruys, PW | 3 |
| Simoons, ML | 2 |
| Meyer, J | 1 |
| Ellrodt, AG | 1 |
| Singh, BN | 13 |
| Dunn, JM | 1 |
| Groth, PE | 1 |
| Kessler, H | 1 |
| Smith, HJ | 4 |
| Aronow, WS | 4 |
| Kaltenbach, M | 6 |
| Kober, G | 2 |
| Schmidt-Moritz, A | 1 |
| Scherer, D | 1 |
| Campolo, L | 1 |
| Casolo, F | 1 |
| Pirelli, S | 1 |
| Inglese, E | 1 |
| Ellrodt, G | 2 |
| Chew, CY | 6 |
| Hamamoto, H | 2 |
| Peter, T | 3 |
| Fujimoto, T | 3 |
| Mandel, WJ | 4 |
| Ewy, GA | 1 |
| Nami, R | 1 |
| Martinelli, M | 1 |
| Lo Monaco, B | 1 |
| Pizzuti, M | 1 |
| Nardi, PL | 1 |
| D'Ascenzo, G | 1 |
| Gennari, C | 1 |
| Grinwald, P | 1 |
| Clusin, WT | 2 |
| Bristow, MR | 1 |
| Karagueuzian, HS | 2 |
| Katzung, BG | 1 |
| Mitchell, LB | 1 |
| Mason, JW | 1 |
| Thandroyen, FT | 1 |
| Surawicz, B | 1 |
| Zipes, DP | 5 |
| Gilmour, RF | 3 |
| Winniford, MD | 2 |
| Willerson, JT | 2 |
| Hillis, LD | 2 |
| Van Bogaert, A | 1 |
| De Schepper, J | 1 |
| Klein, HO | 1 |
| Ninio, R | 1 |
| Oren, V | 1 |
| Lang, R | 1 |
| Sareli, P | 1 |
| DiSegni, E | 1 |
| David, D | 1 |
| Guerrero, J | 2 |
| Kaplinsky, E | 2 |
| Bersohn, MM | 1 |
| Shine, KI | 2 |
| Schulte-Sasse, U | 2 |
| Hess, W | 1 |
| Markschies-Hornung, A | 1 |
| Tarnow, J | 2 |
| Tullio, D | 1 |
| Valerio, A | 1 |
| D'Agostino, F | 1 |
| Vlietstra, RE | 3 |
| Farias, MA | 1 |
| Frye, RL | 2 |
| Smith, HC | 1 |
| Ritman, EL | 1 |
| Hess, ML | 1 |
| Greenfield, LJ | 1 |
| Patton, JN | 1 |
| Amoroso, A | 2 |
| Lanciotti, G | 1 |
| Mammarella, A | 1 |
| Zatuchni, J | 1 |
| Osbakken, M | 1 |
| Briggs, RW | 1 |
| Klein, WW | 1 |
| Hopf, R | 2 |
| Drews, H | 1 |
| Ribeiro, JM | 1 |
| Sadi, J | 1 |
| Barros, FA | 1 |
| Brown, BG | 3 |
| Wong, MM | 1 |
| Pierce, C | 1 |
| Petersen, R | 1 |
| Forman, R | 1 |
| Eng, C | 1 |
| Kirk, ES | 1 |
| Iskandrian, AS | 1 |
| Hakki, AH | 1 |
| DePace, NL | 1 |
| Manno, B | 1 |
| Segal, BL | 1 |
| Brügmann, U | 1 |
| Blasini, R | 1 |
| Rudolph, W | 2 |
| Michels, R | 1 |
| Tereshchenko, VP | 2 |
| Hasin, Y | 3 |
| Kriwisky, M | 1 |
| Gotsman, MS | 1 |
| Lange, R | 1 |
| Ingwall, J | 1 |
| Hale, SL | 1 |
| Alker, KJ | 2 |
| Braunwald, E | 5 |
| Fagbemi, O | 1 |
| Kane, KA | 1 |
| McDonald, FM | 1 |
| Parratt, JR | 2 |
| Rothaul, AL | 1 |
| Curtis, MJ | 5 |
| MacLeod, BA | 1 |
| Walker, MJ | 5 |
| Konishi, T | 2 |
| Nakamura, Y | 5 |
| Kawai, C | 2 |
| Brandt, D | 1 |
| Belhassen, B | 1 |
| Horowitz, LN | 1 |
| Reimer, KA | 4 |
| Jennings, RB | 4 |
| Couper, GS | 1 |
| Weiss, J | 1 |
| Hiltbrand, B | 1 |
| Turitto, G | 1 |
| Dini, P | 1 |
| Rocca, P | 1 |
| Vicari, M | 1 |
| Zanchi, E | 1 |
| Prati, PL | 1 |
| Silke, B | 4 |
| Verma, SP | 4 |
| Ahuja, RC | 1 |
| Nelson, GI | 1 |
| Hussain, M | 1 |
| Taylor, SH | 4 |
| Simon, R | 2 |
| de Jong, JW | 1 |
| Abu-Jawdeh, C | 1 |
| Hatem, J | 1 |
| Alanen, KA | 1 |
| Lipasti, JA | 1 |
| Tasanne, MR | 1 |
| Nevalainen, TJ | 1 |
| Sućić, M | 1 |
| Schiemann, J | 1 |
| Shinbaeva, NA | 2 |
| Pushkar', IuT | 1 |
| Metelitsa, VI | 5 |
| Bagger, JP | 1 |
| Nielsen, TT | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| INternational VErapamil SR Trandolapril STudy[NCT00133692] | Phase 4 | 22,000 participants | Interventional | 1997-09-30 | Completed | ||
| Heart Rate Controller in Computed Tomography Coronary Angiography: A Randomized Controlled Trial of Metoprolol, Diltiazem and Ivabradine[NCT05261464] | Phase 4 | 246 participants (Anticipated) | Interventional | 2021-01-30 | Recruiting | ||
| Comparism Between Efficacy and Effectiveness Between Slow Infusion of Calcium Channel Blockers and Intravenous Bolus Adenosine in the Management of Supraventricular Tachycardia in the Emergency Department.[NCT00413712] | Phase 4 | 206 participants | Interventional | 1997-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
63 reviews available for verapamil and Coronary Disease
| Article | Year |
|---|---|
[The no-reflow phenomenon and its clinical significance].
Topics: Adenosine; Angioplasty, Balloon, Coronary; Atherectomy; Coronary Angiography; Coronary Artery Bypass | 2002 |
Clinical and potential use of pharmacological agents to reduce radial artery spasm in coronary artery surgery.
Topics: Anastomosis, Surgical; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Drug Therapy, | 2008 |
Calcium channel blockers as antihypertensive agents.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; | 1984 |
Prevention of cardiogenic shock.
Topics: Adrenergic beta-Antagonists; Coronary Disease; Creatine Kinase; Echocardiography; Electrocardiograph | 1980 |
[Use of calcium antagonists in the therapy of coronary heart disease].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium; Coronary Disease; Diltiazem; Drug Therapy, Co | 1983 |
Clinical applications of slow channel blocking compounds.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Platelets; Blood Vessels; Calcium | 1983 |
Calcium antagonists and their potential role in the prevention of sudden coronary death.
Topics: Action Potentials; Animals; Atrial Fibrillation; Atrial Flutter; Atrioventricular Node; Calcium Chan | 1982 |
Calcium antagonists in the treatment of individuals with ischemic heart disease.
Topics: Angina Pectoris; Angina Pectoris, Variant; Calcium; Calcium Channel Blockers; Coronary Disease; Dilt | 1982 |
[Calcium antagonists in cardiology].
Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Disease; Dilt | 1983 |
Calcium entry blockers: potential applications in shock.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Diltiazem; Dogs | 1983 |
[Calcium antagonists. Properties and current indications].
Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiaze | 1984 |
Nuclear magnetic resonance: theory and review of cardiac applications.
Topics: Adenosine Triphosphate; Animals; Blood Circulation; Carbon Isotopes; Coronary Circulation; Coronary | 1984 |
Treatment of hypertension with calcium channel blockers: European data.
Topics: Age Factors; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Diltiazem; Europe; Humans; | 1984 |
Evaluation of left ventricular function by radionuclide angiography during exercise in normal subjects and in patients with chronic coronary heart disease.
Topics: Age Factors; Coronary Disease; Exercise Test; Heart Rate; Heart Ventricles; Humans; Isometric Contra | 1983 |
Part I: pharmacologic and hemodynamic actions and interactions. Pharmacologic and hemodynamic mechanisms underlying the antianginal actions of verapamil.
Topics: Angina Pectoris; Animals; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Dogs; | 1982 |
[Treatment of angina pectoris with calcium antagonists].
Topics: Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Therapy, Combination; E | 1982 |
Calcium entry blockers: uses and implications for anesthesiologists.
Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Biotransformation; Calcium Channel Blockers; Cor | 1982 |
[Indications for use of calcium antagonists].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Coronary Disease | 1980 |
[Utilization of anti-arrhythmic drugs].
Topics: Action Potentials; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Digital | 1980 |
The role of calcium in the ischemic myocardium.
Topics: Adenosine Triphosphate; Animals; Calcium; Coronary Disease; Cytosol; Hypothermia; Male; Mitochondria | 1981 |
[Pharmacological aspects and therapeutic uses of verapamil and related calcium antagonists (author's transl)].
Topics: Animals; Arrhythmias, Cardiac; Calcium; Coronary Circulation; Coronary Disease; Electrocardiography; | 1980 |
Role of calcium antagonists in cardiovascular therapy.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Blood Vessels; Calcium; Calcium Channel Blockers; Cardiomyopa | 1981 |
The clinical use of verapamil.
Topics: Administration, Oral; Adult; Animals; Arrhythmias, Cardiac; Biological Availability; Calcium; Cardio | 1982 |
Anti-ischemic intervention as prognosis improvement in patients with coronary artery disease, with special focus on verapamil.
Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; Heart Failure; Humans; Myocardial | 1996 |
The effects of calcium antagonists after PTCA.
Topics: Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Clinical Trials as Topic; Constriction, Pa | 1995 |
Verapamil: a review of its pharmacological properties and therapeutic use in coronary artery disease.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Disease; Humans; Myocardial Infarction; | 1996 |
Preclinical considerations and results with the combination of verapamil and trandolapril: blood pressure reduction and beyond.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Diabet | 1997 |
Some similarities and differences between verapamil and the dihydropyridines.
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; Dihydropy | 1998 |
[Biochemical mechanisms of action of coronarodilating agents (review of the literature)].
Topics: Adrenergic beta-Antagonists; Aminophylline; Animals; Chromonar; Coronary Disease; Coronary Vessels; | 1976 |
[Calcium antagonists in cardiology].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Calcium; Coronary Disease; Human | 1978 |
Cardiac electrophysiologic alterations during myocardial ischemia.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Biological Transport; Coronary Disease; Dogs; Elec | 1977 |
Verapamil: a review of its pharmacological properties and therapeutic use.
Topics: Angina Pectoris; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Corona | 1978 |
[Hypertrophic cardiomyopathy with obstruction].
Topics: Adolescent; Adult; Aged; Angina Pectoris; Cardiac Glycosides; Cardiomyopathy, Hypertrophic; Coronary | 1979 |
Clinical aspects of Ca-blocking agents.
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Calcium; Coronary Disease; Cricetinae; Humans; Hyper | 1978 |
[Medical therapy of chronic coronary insufficiency].
Topics: Amiodarone; Angina Pectoris; Chronic Disease; Coronary Disease; Digitalis Glycosides; Humans; Lidofl | 1978 |
[Possibilities of preserving ischemic myocardium].
Topics: Acute Disease; Animals; Coronary Circulation; Coronary Disease; Dipyridamole; Fibrinolysis; Humans; | 1976 |
[Effects of calcium antagonists on carbohydrate and lipid metabolism].
Topics: Animals; Calcium Channel Blockers; Carbohydrate Metabolism; Cholesterol; Coronary Disease; Diabetes | 1992 |
Calcium antagonists and myocardial microperfusion.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Gallopamil; Guinea Pigs; | 1991 |
Protective effects of calcium antagonists against ischaemia and reperfusion damage.
Topics: Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Humans; Myocardial Reperfusion Injur | 1991 |
Basic mechanisms involved in the protection of the ischaemic myocardium. The role of calcium antagonists.
Topics: Calcium; Calcium Channel Blockers; Coronary Disease; Humans; Myocardial Reperfusion Injury; Myocardi | 1991 |
Prevention of restenosis after PTCA: role of calcium antagonists.
Topics: Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Disease; Diltiazem; Double- | 1991 |
Calcium-antagonists in preventing restenosis following coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease | 1991 |
[Cardiovascular therapy with calcium antagonists].
Topics: Calcium Channel Blockers; Coronary Disease; Electrocardiography; Hemodynamics; Humans; Myocardial In | 1991 |
Verapamil and ventricular tachyarrhythmias.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Electrophysiology; Heart Ventricle | 1987 |
[Verapamil: a 1st choice antihypertensive agent].
Topics: Coronary Disease; Diabetes Complications; Humans; Hypertension; Sodium, Dietary; Verapamil | 1989 |
Large vessel coronary vasospasm: diagnosis, natural history and treatment.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aspirin; Coronary Artery Bypass; Coronary | 1985 |
Calcium antagonists.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium; Calcium Channel Blockers; Coronary Circulatio | 1985 |
The haemodynamic effects of nifedipine, verapamil and diltiazem in patients with coronary artery disease. A review.
Topics: Adrenergic beta-Antagonists; Benzazepines; Calcium Channel Blockers; Coronary Circulation; Coronary | 1986 |
Calcium channel antagonists. Part II: Use and comparative properties of the three prototypical calcium antagonists in ischemic heart disease, including recommendations based on an analysis of 41 trials.
Topics: Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Thera | 1988 |
Effect of verapamil on postischemic "stunned" myocardium: importance of the timing of treatment.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dog | 1988 |
Calcium channel blocking agents in congestive heart failure.
Topics: Administration, Oral; Biological Transport; Calcium; Calcium Channel Blockers; Cardiac Output; Cardi | 1986 |
Advances in calcium blocker therapy.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Asthma; Blood Platelet Disorders; Calcium; Calcium Channel B | 1986 |
Mechanisms involved in reperfusion arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Dil | 1986 |
Effects of calcium-channel blockers on myocardial preservation during experimental acute myocardial infarction.
Topics: Animals; Calcium Channel Blockers; Collateral Circulation; Coronary Circulation; Coronary Disease; D | 1985 |
Calcium antagonists for acute ischemic heart disease.
Topics: Acute Disease; Angina Pectoris, Variant; Angina, Unstable; Calcium Channel Blockers; Coronary Diseas | 1985 |
Effects of calcium-channel blocking agents on left ventricular diastolic function in hypertrophic cardiomyopathy and in coronary artery disease.
Topics: Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Disease; Heart Ventricles; Hemodyna | 1985 |
Are calcium antagonists cardioprotective?
Topics: Angina Pectoris; Animals; Blood Viscosity; Calcium Channel Blockers; Clinical Trials as Topic; Coron | 1985 |
Calcium channel blocking agents: physiologic basis of nursing intervention.
Topics: Angina Pectoris; Angina Pectoris, Variant; Atrioventricular Node; Calcium; Calcium Channel Blockers; | 1985 |
Response of normal and diseased epicardial coronary arteries to vasoactive drugs: quantitative arteriographic studies.
Topics: Arterial Occlusive Diseases; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Coron | 1985 |
[Myocardial cellular mechanism of action of calcium antagonists].
Topics: Actin Cytoskeleton; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Heart; Humans; M | 1985 |
Pharmacological aspects of the coronary circulation.
Topics: Adenine Nucleotides; Angina Pectoris; Angiotensin II; Animals; Atrial Function; Blood Pressure; Coro | 1969 |
[Recent data on coronary dilators].
Topics: Amino Alcohols; Aminophylline; Animals; Benzofurans; Cardiovascular Diseases; Cats; Coronary Disease | 1968 |
Comparison of therapeutic effects of coronary drugs in the USSR.
Topics: Angina Pectoris; Benzoates; Benzyl Compounds; Clinical Trials as Topic; Coronary Disease; Coumarins; | 1971 |
91 trials available for verapamil and Coronary Disease
| Article | Year |
|---|---|
beta-adrenergic receptor gene polymorphisms and beta-blocker treatment outcomes in hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Confidence Intervals; Coronary Disease; Dose-Response R | 2008 |
Pulse pressure and risk of cardiovascular outcomes in patients with hypertension and coronary artery disease: an INternational VErapamil SR-trandolapril STudy (INVEST) analysis.
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Coronary Artery Disease; Coronary Disease; | 2009 |
Variation in the human soluble epoxide hydrolase gene and risk of restenosis after percutaneous coronary intervention.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Case-Control Studies; Coronar | 2009 |
Effects of papaverine and glycerylnitrate-verapamil solution as topical and intraluminal vasodilators for internal thoracic artery.
Topics: Administration, Topical; Aged; Blood Flow Velocity; Coronary Disease; Electrocoagulation; Female; Hu | 2006 |
Comparison of the effects of nicorandil versus verapamil on the incidence of slow flow/no reflow during rotational atherectomy.
Topics: Aged; Anticoagulants; Atherectomy, Coronary; Biomarkers; Coronary Circulation; Coronary Disease; Cre | 2006 |
[Effects of Verapamil and Metoprolol on heart rate variability in patients with coronary heart disease].
Topics: Anti-Arrhythmia Agents; Coronary Disease; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; | 2007 |
Calcium channel blockers as antihypertensive agents.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; | 1984 |
The value of anti-anxiety drugs in the management of cardiac disease.
Topics: Anti-Anxiety Agents; Antihypertensive Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotas | 1982 |
Calcium channel blockers: indications and limitations 2. Use in angina and other cardiac disorders.
Topics: Administration, Oral; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blockers; Cardiomeg | 1982 |
Calcium channel blocking agents.
Topics: Benzazepines; Calcium; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Di | 1981 |
Effect of verapamil on left ventricular function: a randomized, placebo-controlled study.
Topics: Cardiac Catheterization; Clinical Trials as Topic; Coronary Angiography; Coronary Disease; Female; H | 1983 |
Randomized, placebo-controlled study of the effect of verapamil on exercise hemodynamics in coronary artery disease.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Exercise Test | 1984 |
[Calcium antagonists. Properties and current indications].
Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiaze | 1984 |
[Anti-angina effect of gallopamil in comparison with another calcium antagonist and a placebo].
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Bli | 1984 |
[Cross double-blind study with verapamil x placebo in ischemic heart disease with an ergometric test].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Exerci | 1984 |
[Comparison of the anti-ischemia effect of nisoldipine and verapamil. Double-blind randomized cross-over and placebo-controlled acute and long-term study].
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Diseas | 1984 |
Effects of verapamil in patients with acute myocardial infarction: hemodynamics and function of normal and ischemic left ventricular myocardium.
Topics: Adult; Aged; Coronary Disease; Drug Evaluation; Echocardiography; Electrocardiography; Female; Heart | 1984 |
Verapamil therapy for unstable angina pectoris: review of double-blind placebo-controlled randomized clinical trials.
Topics: Adult; Aged; Angina Pectoris; Arterial Occlusive Diseases; Clinical Trials as Topic; Coronary Diseas | 1982 |
[Comparative study of verapamil and fendiline in the treatment of chronic coronary insufficiency. Clinical and ergometric evaluation].
Topics: Chronic Disease; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Electrocardiograph | 1982 |
Verapamil in chronic stable angina: a controlled study with computerized multistage treadmill exercise.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Bli | 1980 |
Radionuclide evaluation of CHF.
Topics: Adolescent; Adult; Coronary Disease; Digoxin; Female; Heart Aneurysm; Heart Failure; Hemodynamics; H | 1981 |
Pharmacological effects on coronary haemodynamics. A comparative study between atenolol, verapamil, nifedipine and carbocromen.
Topics: Atenolol; Chromonar; Coronary Circulation; Coronary Disease; Coumarins; Hemodynamics; Humans; Nifedi | 1981 |
Coronary spasm management with verapamil (Isoptin).
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Elec | 1980 |
Vasospastic angina.
Topics: Angina Pectoris; Angina Pectoris, Variant; Angiocardiography; Clinical Trials as Topic; Coronary Dis | 1980 |
Mechanism of action of verapamil in ischemic heart disease: observations on changes in systemic and coronary hemodynamics and coronary vasomobility.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; Heart Rate; | 1980 |
Comparative effects of oral verapamil and propranolol on exercise-induced myocardial ischemia and energetics in patients with coronary artery disease: single-blind placebo crossover evaluation using radionuclide ventriculography.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Exerci | 1982 |
Effects of verapamil and propranolol on left ventricular systolic function and diastolic filling in patients with coronary artery disease: radionuclide angiographic studies at rest and during exercise.
Topics: Adult; Blood Pressure; Coronary Disease; Erythrocytes; Female; Heart; Heart Rate; Heart Ventricles; | 1982 |
[Ergometric and clinical results of treating coronary disease with isosorbide dinitrate and verapamil].
Topics: Coronary Disease; Drug Therapy, Combination; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Mal | 1981 |
[Comparative pharmacodynamics study of korinfar and isoptin in ischemic heart disease].
Topics: Adult; Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Drug Evaluation; Exercis | 1981 |
[Calcium antagonists and primary prevention of coronary disease].
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Double-Blind Method; Female; Humans; Male; Metoprolo | 1995 |
Verapamil treatment after coronary angioplasty in patients at high risk of recurrent stenosis.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Coronary Angiography; Coronary Disease; Dipyridamole; | 1994 |
[Treatment of ischemic heart disease in the elderly. Comparison of diltiazem, verapamil and gallopamil].
Topics: Age Factors; Aged; Angina Pectoris; Coronary Angiography; Coronary Disease; Diltiazem; Drug Evaluati | 1993 |
Effect of high dose verapamil on restenosis after peripheral angioplasty.
Topics: Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Disease; Double-Blind Metho | 1998 |
Circadian blood pressure changes and myocardial ischemia in hypertensive patients with coronary artery disease.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian | 1998 |
Rationale and design of the International Verapamil SR/Trandolapril Study (INVEST): an Internet-based randomized trial in coronary artery disease patients with hypertension.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary | 1998 |
Verapamil reduces dipyridamole-induced myocardial ischemia in patients with coronary artery disease.
Topics: Aged; Calcium Channel Blockers; Coronary Angiography; Coronary Disease; Dipyridamole; Echocardiograp | 1999 |
Verapamil and risk of cancer in patients with coronary artery disease. DAVIT Study Group. Danish Verapamil Infarction Trial.
Topics: Aged; Calcium Channel Blockers; Coronary Disease; Female; Humans; Male; Middle Aged; Neoplasms; Rand | 1999 |
Effects of intracoronary nicardipine, diltiazem and verapamil on coronary blood flow.
Topics: Aged; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Coronary Vessels; Diltiazem; | 2000 |
[Drug therapy of coronary heart disease (author's transl)].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium; Clinical Trials as Topic; Coronary Disease; D | 1977 |
[Effect of verapamil on echocardiographic dimensions of the left ventricle in ischemic cardiopathy: comparison with placebo, propranolol and trinitroglycerin].
Topics: Adult; Clinical Trials as Topic; Coronary Disease; Echocardiography; Humans; Male; Middle Aged; Myoc | 1979 |
[Electrocardiographic and hemodynamic disorders induced by verapamil: experimental study].
Topics: Animals; Clinical Trials as Topic; Coronary Disease; Dogs; Drug Evaluation; Electrocardiography; Fem | 1977 |
[Cycloergometric evaluation of the continuous use of verapamil 360 mg/per day in chronic coronary insufficiency].
Topics: Administration, Oral; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Drug | 1977 |
[Cycloergometric evaluation of the effects of verapamil in chronic coronary insufficiency].
Topics: Administration, Oral; Adult; Aged; Body Weight; Chronic Disease; Clinical Trials as Topic; Coronary | 1977 |
[Effects of verapamil on the cycloergometric test in patients of coronary artery disease].
Topics: Administration, Oral; Adult; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Drug Evalu | 1977 |
Effects of drugs upon exercise tests in coronary insuffiency.
Topics: Adult; Clinical Trials as Topic; Coronary Disease; Drug Evaluation; Electrocardiography; Exercise Te | 1977 |
Effects of intravenous verapamil on hemodynamics in patients with heart disease.
Topics: Adult; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Coronary Disease; Depression, Chemi | 1977 |
[Coronary disease. Clinical experience with a new active substance combination].
Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Drug Combinations; Female; Humans; Isosorbi | 1977 |
[Coronary sclerosis and angina pectoris. Clinical, double-blind study using Stenoptin].
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Drug Combinations; | 1978 |
[Initial experience. Comparative study of verapamil and nifedipine in the treatment of coronary insufficiency. Evaluation by a cycloergometric test].
Topics: Adult; Aged; Chronic Disease; Cineangiography; Clinical Trials as Topic; Coronary Disease; Double-Bl | 1978 |
Effects of verapamil on myocardial performance in coronary disease.
Topics: Angina Pectoris; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Coronary Disease; Heart; | 1979 |
[Use of verapamil in the treatment of ventricular extrasystole in chronic Chagas' heart disease].
Topics: Cardiomyopathies; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Drug | 1977 |
Verapamil in ischaemic heart disease--quantitative assessment by serial multistage treadmill exercise.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Drug Evaluation; Exercise | 1976 |
Treatment of transient myocardial ischemia in patients with stable angina: a comparative study of verapamil slow-release and nifedipine plus propranolol.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Delayed-Action Preparations; Drug Therapy, Combinati | 1992 |
Prevalence of transient myocardial ischaemia during the first year after a myocardial infarction. Effect of treatment with verapamil. The Danish Study Group on Verapamil in Myocardial Infarction.
Topics: Aged; Circadian Rhythm; Coronary Disease; Denmark; Double-Blind Method; Drug Administration Schedule | 1992 |
[Hemodynamic and clinical studies with Bonnecor--a new anti-arrhythmia drug].
Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiomyopathy, H | 1990 |
Prevention of restenosis after PTCA: role of calcium antagonists.
Topics: Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Disease; Diltiazem; Double- | 1991 |
Effect of verapamil on ischemia and ventricular arrhythmias after an acute myocardial infarction: prognostic implications. The Danish Verapamil Infarction Trial II Study Group.
Topics: Analysis of Variance; Arrhythmias, Cardiac; Coronary Disease; Female; Heart Rate; Humans; Male; Myoc | 1991 |
The effect of verapamil on major events in patients with exercise-induced ischemia recovering from acute myocardial infarction: a review. The Danish Study Group on Verapamil in Myocardial Infarction.
Topics: Blood Pressure; Coronary Disease; Double-Blind Method; Electrocardiography; Exercise Test; Female; H | 1991 |
[The effect of finoptin on platelet aggregation, blood coagulability and fibrinolysis in patients with ischemic heart disease during physical exercise].
Topics: Adult; Blood Coagulation; Coronary Disease; Exercise Test; Fibrinolysis; Humans; Male; Middle Aged; | 1991 |
Randomized double-blind comparison of the effects of isosorbide dinitrate retard, verapamil sustained-release, and their combination on myocardial ischemic episodes.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Delayed-Action Preparations; Double- | 1991 |
Differences in response to single dose and steady-state therapy with verapamil in stable angina.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Double-Blind M | 1991 |
Calcium-antagonists in preventing restenosis following coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease | 1991 |
Secondary prevention of death and reinfarction with verapamil after an acute myocardial infarction. The Danish Study Group on Verapamil in Myocardial Infarction.
Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Coronary Disease; Death, Sudden; Denmark; Double-Bl | 1990 |
An exercise hemodynamic comparison of verapamil, diltiazem, and amlodipine in coronary artery disease.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Diltiazem; | 1990 |
[Effect of the optimal dose of finoptin on various components of the circulatory system in heart failure in patients with ischemic heart disease].
Topics: Administration, Sublingual; Adult; Aged; Cardiomyopathy, Dilated; Coronary Disease; Dose-Response Re | 1990 |
[The effect of calcium antagonists on the hemodynamic function in patients with heart failure].
Topics: Calcium Channel Blockers; Cardiography, Impedance; Coronary Disease; Echocardiography; Heart Failure | 1990 |
[The results of a clinical study of the preparation kardil].
Topics: Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Humans; Hypertension; Nifedipine; USS | 1990 |
Verapamil and ventricular tachyarrhythmias.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Electrophysiology; Heart Ventricle | 1987 |
[Cross-over double-blind study of verapamil versus diltiazem in effort myocardial ischemia].
Topics: Coronary Disease; Diltiazem; Double-Blind Method; Female; Humans; Male; Middle Aged; Physical Exerti | 1989 |
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.
Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Re | 1987 |
[Effects of chronic administration of several calcium antagonists on pituitary release of TSH].
Topics: Adult; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Hyper | 1987 |
[The cardioprotective effect of verapamil in acute percutaneous transluminal coronary angioplasty].
Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon; Clinical Trials as Topic; Coronary Circulation; | 1988 |
Lack of effect of warfarin on the restenosis rate or on clinical outcome after balloon coronary angioplasty.
Topics: Adult; Aged; Angioplasty, Balloon; Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combina | 1988 |
Effectiveness of calcium antagonist drugs in patients with unstable angina and proven coronary artery disease.
Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Calcium; Coronary Disease; Diltiazem; Electrocardiog | 1988 |
Comparison of nicardipine and verapamil in the management of chronic stable angina.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Bli | 1988 |
Calcium-channel blockers for combined angina pectoris and systemic hypertension.
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chr | 1986 |
Randomized placebo-controlled comparative study of nifedipine, verapamil and isosorbide dinitrate in the treatment of angina at rest.
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Delayed-Action Preparations; Dose-Respo | 1986 |
Equal anti-ischemic properties of isosorbide dinitrate plus verapamil and isosorbide dinitrate plus propranolol. A randomized, double-blind and crossover study.
Topics: Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Drug Therapy, Combi | 1986 |
Calcium-channel blockers for combined systemic hypertension and myocardial ischemia.
Topics: Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Clinical Trials as Topic; Coronary Disea | 1987 |
Effects of verapamil and nifedipine on rate of left ventricular relaxation in coronary arterial disease patients.
Topics: Blood Pressure; Coronary Disease; Diastole; Heart Ventricles; Hemodynamics; Humans; Male; Middle Age | 1987 |
Improvement in left ventricular diastolic function in patients with stable angina after chronic treatment with verapamil and nicardipine.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Diastole; Double-Blind Method; Female; Heart Functio | 1987 |
Are calcium antagonists cardioprotective?
Topics: Angina Pectoris; Animals; Blood Viscosity; Calcium Channel Blockers; Clinical Trials as Topic; Coron | 1985 |
Calcium blockers and beta blockers: alone and in combination.
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combination; Electrocardi | 1985 |
Oral verapamil for prophylaxis of supraventricular tachycardia after myocardial revascularization. A randomized trial.
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Coronary Disease; Drug Evaluation; Fema | 1985 |
[Effect of isoptin on hemodynamics in patients with hypertension and ischemic heart disease].
Topics: Adult; Clinical Trials as Topic; Coronary Disease; Female; Hemodynamics; Humans; Hypertension; Injec | 1985 |
[Differential therapy with calcium antagonists. Hemodynamic studies using nifedipine, verapamil and diltiazem].
Topics: Calcium Channel Blockers; Coronary Disease; Diltiazem; Exercise Test; Heart Rate; Hemodynamics; Huma | 1985 |
[Isoptin treatment of patients with various forms of chronic coronary insufficiency].
Topics: Adult; Aged; Angina Pectoris; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Clinica | 1970 |
Comparison of therapeutic effects of coronary drugs in the USSR.
Topics: Angina Pectoris; Benzoates; Benzyl Compounds; Clinical Trials as Topic; Coronary Disease; Coumarins; | 1971 |
[The antiarrhythmic and coronary-dilating properties of verapamil in patients ith ischemic heart disease].
Topics: Adult; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Arteriosclerosis; Bloo | 1970 |
[The effectiveness of treating patients with coronary insufficiency with verapamil].
Topics: Acid-Base Equilibrium; Adult; Aged; Anti-Arrhythmia Agents; Blood Circulation; Blood Flow Velocity; | 1970 |
[Clinical study of verampamil in the treatment of patients with chronic coronary insufficiency].
Topics: Adult; Aged; Angina Pectoris; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Arteriosclerosis; Corona | 1970 |
453 other studies available for verapamil and Coronary Disease
| Article | Year |
|---|---|
Safety and efficacy of a rate control protocol for cardiac CT.
Topics: Anti-Arrhythmia Agents; Artifacts; Clinical Protocols; Coronary Angiography; Coronary Disease; Dose- | 2009 |
Resolution of refractory no-reflow with intracoronary epinephrine.
Topics: Abciximab; Acute Disease; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Bl | 2002 |
Population analyses of sustained-release verapamil in patients: effects of sex, race, and smoking.
Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Coronary Disease | 2003 |
Mibefradil: "Has the baby been thrown out with the bath water?".
Topics: Angina Pectoris; Calcium Channel Blockers; Calcium Channels, T-Type; Coronary Disease; Coronary Vess | 2003 |
[CLINICAL STUDY OF THE EFFECT OF ISOPTIN AND ISOPTIN S IN PATIENTS WITH CORONARY INSUFFICIENCY].
Topics: Coronary Artery Disease; Coronary Disease; Cyanides; Humans; Vasodilator Agents; Verapamil | 1963 |
[TREATMENT OF CORONARY CIRCULATORY DISORDERS WITH ISOPTIN IN GENERAL PRACTICE].
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Coronary Disease; Drug Therapy; Electrocardiography; Genera | 1964 |
[ISOPTIN (D-365), CLINICAL STUDIES ON THE TREATMENT OF CORONARY HEART DISEASE].
Topics: Anti-Arrhythmia Agents; Biomedical Research; Coronary Artery Disease; Coronary Disease; Humans; Vaso | 1965 |
[DRUG THERAPY OF CORONARY INSUFFICIENCY].
Topics: Anti-Arrhythmia Agents; Coronary Artery Disease; Coronary Disease; Humans; Myocardial Infarction; Ve | 1965 |
[ISOPTIN, A NEW CORONARY DILATOR].
Topics: Cardiomegaly; Coronary Disease; Drug Therapy; Humans; Vasodilator Agents; Verapamil | 1964 |
Inhibition of ultra-rapid delayed rectifier K+ current by verapamil in human atrial myocytes.
Topics: 4-Aminopyridine; Adult; Aged; Coronary Disease; Heart Atria; Humans; Kinetics; Membrane Potentials; | 2004 |
Effects of adenosine and verapamil on anatomic no-reflow in a rabbit model of coronary artery occlusion and reperfusion.
Topics: Adenosine; Animals; Blood Pressure; Coronary Disease; Coronary Vasospasm; Disease Models, Animal; Ma | 2004 |
VISP and INVEST.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; | 2004 |
Managing hypertension in European patients with coronary artery disease: design, results, and clinical implications of INVEST.
Topics: Antihypertensive Agents; Coronary Disease; Drug Therapy, Combination; Europe; Humans; Hypertension; | 2004 |
[Characteristic features of the pathogenesis and treatment of coronary heart diseases, heart failure and arterial hypertension in patients with diabetes mellitus].
Topics: Adrenergic beta-Antagonists; Adult; Aspirin; Blood Glucose; Calcium Channel Blockers; Clinical Trial | 2005 |
A drug dose model for predicting clinical outcomes in hypertensive coronary disease patients.
Topics: Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Chi-Square Distribution; Coronary Disea | 2005 |
Blood pressure control and cardiovascular outcomes in high-risk Hispanic patients--findings from the International Verapamil SR/Trandolapril Study (INVEST).
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Case-Control Studies; Cohort Studies; Coron | 2006 |
Unusual complication of transradial catheterization.
Topics: Brachial Artery; Cardiac Catheterization; Cardiology; Coronary Disease; Humans; Male; Middle Aged; N | 2006 |
[Beta-blocking drugs in coronary insufficiency. Clinical experiences with iproveratril].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Disease; Female; Humans; Male; Middle Aged; Sympatholy | 1967 |
[Experimental basis for treatment with coronary dilators].
Topics: Angina Pectoris; Animals; Anti-Arrhythmia Agents; Coronary Disease; Humans; Oxygen Consumption; Prop | 1967 |
[Drug therapy of coronary disease. Beta receptor blockers, calcium antagonists, digitalis glycosides and further therapeutic aspects].
Topics: Adrenergic beta-Antagonists; Calcium; Coronary Disease; Digitalis Glycosides; Humans; Nifedipine; Ve | 1980 |
Welcome--the calcium channel blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium Channel Blocker | 1981 |
Calcium-entry blockade, beta-adrenergic blockade and the reflex control of circulation.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Disease; Drug Therapy, Combination; Hemodynam | 1982 |
Calcium channel blockers: rationale for their clinical use.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Calcium; Calcium Channel Blockers; Coronary Disea | 1981 |
Recent concepts in the management of ischaemic cardiac syndromes.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blockers; Co | 1982 |
[Reperfusion ventricular fibrillation in the dog].
Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Dogs; Ligation; Metipranolo | 1982 |
Adverse interaction between beta-adrenergic blocking drugs and verapamil--report of three cases.
Topics: Adrenergic beta-Antagonists; Aged; Bradycardia; Coronary Disease; Drug Interactions; Drug Therapy, C | 1982 |
The pharmacological protection of the ischaemic heart: the use of calcium and beta-adrenoceptor antagonists.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Coronary Dis | 1980 |
Effects of an electrical field and its polarity on an abnormal part of the body or organ representation point associated with a diseased internal organ, and its influence on the Bi-Digital O-Ring Test (simple, non-invasive dysfunction localization method)
Topics: Acupuncture Therapy; Adult; Aspirin; Brain Ischemia; Child; Coronary Disease; Electric Stimulation T | 1982 |
What is preferable in unstable angina, beta-blockade or calcium-inhibition?
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Dise | 1983 |
Once-daily verapamil.
Topics: Administration, Oral; Coronary Disease; Humans; Verapamil | 1984 |
[Long-term study with Stenoptin in general practice].
Topics: Angina Pectoris; Cardiac Complexes, Premature; Coronary Disease; Drug Combinations; Drug Evaluation; | 1980 |
Depressed contractile function in reperfused canine myocardium: metabolism and response to pharmacological agents.
Topics: Animals; Calcimycin; Coronary Circulation; Coronary Disease; Dogs; Heart; Isoproterenol; Lactates; M | 1980 |
[Incidence of recurrence after successful transluminal coronary angioplasty].
Topics: Angioplasty, Balloon; Aspirin; Coronary Disease; Exercise Test; Humans; Isosorbide Dinitrate; Premed | 1983 |
Percutaneous transluminal coronary angioplasty. Critical assessment of preliminary results.
Topics: Angioplasty, Balloon; Constriction, Pathologic; Coronary Disease; Humans; Nitrates; Premedication; V | 1984 |
Therapeutic implications of slow-channel blockade in cardiocirculatory disorders.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium; Cardiovascular Diseases; Coronary Disease; Diltiazem | 1980 |
Effect of verapamil on conduction delay produced by myocardial ischemia and reperfusion.
Topics: Animals; Coronary Disease; Dogs; Endocardium; Heart Conduction System; Ion Channels; Male; Perfusion | 1981 |
[Effects of calcium antagonists (verapamil and nifedipine) on blood levels of calcium and cyclic AMP in humans].
Topics: Adult; Calcium; Coronary Disease; Cyclic AMP; Electrocardiography; Electrolytes; Female; Heart; Huma | 1981 |
Calcium entry blockers and myocardial function.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Coronary Disease; Heart; H | 1981 |
Do calcium-dependent ionic currents mediate ischemic ventricular fibrillation?
Topics: Animals; Calcium; Coronary Circulation; Coronary Disease; Death, Sudden; Diltiazem; Heart Conduction | 1982 |
Comparative clinical electrophysiologic effects of diltiazem, verapamil and nifedipine: a review.
Topics: Atrioventricular Node; Benzazepines; Coronary Disease; Diltiazem; Electrocardiography; Heart Rate; H | 1982 |
Protective action of calcium channel antagonist agents against ventricular fibrillation in the isolated perfused rat heart.
Topics: Adenine Nucleotides; Animals; Calcium; Coronary Circulation; Coronary Disease; Cyclic AMP; Diltiazem | 1982 |
Role of calcium-blocking agents in treatment of cardiac arrhythmias related to myocardial ischemia.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiac Output; Ca | 1982 |
Action of a calcium blocking agent (D600) on electrogenesis in the normal heart and the ischaemic heart in the dog.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Coronary Disease; Dogs; Electrocardiography; G | 1982 |
The acute hemodynamic effects of intravenous verapamil in coronary artery disease. Assessment by equilibrium-gated radionuclide ventriculography.
Topics: Adult; Aged; Cardiac Output; Cardiac Volume; Coronary Disease; Depression, Chemical; Dose-Response R | 1983 |
Verapamil protection of ischemic isolated rabbit heart: dependence on pretreatment.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Calcium; Coronary Disease; Creatine; In Vitro Techn | 1983 |
Combined effects of halothane anesthesia and verapamil on systemic hemodynamics and left ventricular myocardial contractility in patients with ischemic heart disease.
Topics: Adult; Coronary Artery Bypass; Coronary Disease; Drug Interactions; Halothane; Hemodynamics; Humans; | 1984 |
Verapamil-digoxin interaction.
Topics: Aged; Coronary Disease; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Heart Arrest; | 1984 |
Effects of verapamil on coronary hemodynamic function and vasomobility relative to its mechanism of antianginal action.
Topics: Aged; Coronary Angiography; Coronary Disease; Hemodynamics; Humans; Infusions, Parenteral; Male; Mid | 1983 |
Comparative effect of verapamil and nitroglycerin on collateral blood flow.
Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Inf | 1983 |
Treatment of unstable angina with emphasis on calcium antagonists.
Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electroca | 1984 |
[Structural changes in the myocardium in experimental acute coronary insufficiency and as affected by pharmacological agents].
Topics: Acute Disease; Animals; Coronary Disease; Drug Evaluation, Preclinical; Heart; Microscopy, Electron; | 1984 |
Verapamil in ventricular tachycardia.
Topics: Adolescent; Adult; Aged; Cardiac Pacing, Artificial; Coronary Disease; Dose-Response Relationship, D | 1984 |
Preservation of high-energy phosphates by verapamil in reperfused myocardium.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Circulatio | 1984 |
The effects of verapamil, prenylamine, flunarizine and cinnarizine on coronary artery occlusion-induced arrhythmias in anaesthetized rats.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel B | 1984 |
Antiarrhythmic actions of verapamil against ischaemic arrhythmias in the rat.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Electric Stimula | 1984 |
Accentuated negative inotropism of verapamil after ischaemic intervention in isolated working rat heart.
Topics: Animals; Blood Pressure; Coronary Disease; Creatine Kinase; Depression, Chemical; In Vitro Technique | 1984 |
[The hypertensive crisis].
Topics: Acute Disease; Calcium Channel Blockers; Clonidine; Coronary Disease; Diazoxide; Dihydralazine; Dilt | 1984 |
Use of intravenous verapamil for ventricular tachycardia.
Topics: Bundle-Branch Block; Coronary Disease; Electrocardiography; Exercise Test; Humans; Infusions, Parent | 1984 |
Verapamil in two reperfusion models of myocardial infarction. Temporary protection of severely ischemic myocardium without limitation of ultimate infarct size.
Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dog | 1984 |
Extracellular pH and tension during ischemia in the isolated rabbit ventricle.
Topics: Acidosis, Respiratory; Animals; Catecholamines; Coronary Disease; Extracellular Space; Heart Rate; H | 1984 |
[Characterization and therapy of ventricular arrhythmias due to transient myocardial ischemic attacks in variant angina].
Topics: Adult; Aged; Angina Pectoris, Variant; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; | 1984 |
Haemodynamic dose-response effects of i.v. verapamil in coronary artery disease.
Topics: Adult; Angina Pectoris; Blood Pressure; Cardiac Output; Coronary Disease; Dose-Response Relationship | 1984 |
[Calcium antagonists: effect on peripheral and coronary hemodynamics].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Coronary Di | 1984 |
Mechanism(s) of calcium antagonists and ischemia.
Topics: Adenosine Triphosphate; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Coronary Circul | 1984 |
Myocardial preservation during heart surgery.
Topics: Aorta; Cardiopulmonary Bypass; Constriction; Coronary Disease; Heart; Heart Arrest, Induced; Humans; | 1984 |
Effect of verapamil on reperfusion damage and calcium paradox in isolated rat heart.
Topics: Animals; Calcium; Coronary Circulation; Coronary Disease; Creatine Kinase; Heart; In Vitro Technique | 1984 |
[Multicenter long-term study of gallopamil in patients with coronary heart disease].
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Electrocardiography; Female; Gallopa | 1984 |
[Study of corinfar and isoptin pharmacodynamics using impedance cardiography and tetrapolar rheoplethysmography of the finger in patients with ischemic heart disease].
Topics: Adult; Calcium Channel Blockers; Cardiac Volume; Coronary Disease; Hemodynamics; Humans; Male; Middl | 1983 |
The effect of verapamil on myocardial exchange of free fatty acids, citrate, lactate and glucose in coronary artery disease.
Topics: Adult; Citrates; Coronary Circulation; Coronary Disease; Fatty Acids, Nonesterified; Glucose; Humans | 1983 |
Study of the electrophysiological effects of early or subendocardial ischaemia with intracavitary electrodes in the dog.
Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Coronary Disease; Dogs; Electrocardiography; | 1983 |
Aspects of the value of continuous ambulatory ECG monitoring in the detection and management of ischaemic heart disease. Case reports.
Topics: Ambulatory Care; Coronary Disease; Electrocardiography; Female; Humans; Male; Middle Aged; Monitorin | 1983 |
Comparative study of the effect of slow channel inhibiting agents on ischemia-induced conduction delay as relevant to the genesis of ventricular fibrillation.
Topics: Animals; Calcium Channel Blockers; Coronary Disease; Diltiazem; Dogs; Heart; Heart Conduction System | 1983 |
[Use of Falicard and Sectral in patients with COPD and ischemic heart disease].
Topics: Angina Pectoris; Atenolol; Coronary Disease; Drug Evaluation; Drug Therapy, Combination; Humans; Lun | 1983 |
Effects of diltiazem on vulnerability to atrial and ventricular reentrant arrhythmias in the normal and ischemic heart.
Topics: Animals; Arrhythmias, Cardiac; Benzazepines; Coronary Disease; Diltiazem; Dogs; Electrophysiology; F | 1983 |
Improvement of the metabolic and energetic situation of ischemically stressed myocardium by verapamil after experimental coronary artery occlusion.
Topics: Animals; Coronary Disease; Coronary Vessels; Dogs; Energy Metabolism; Lactates; Lactic Acid; Myocard | 1983 |
[Interactions between digoxin and amiodarone (Cordarone), verapamil (Isoptin) and melsidomine (Corvatone)].
Topics: Adult; Amiodarone; Cardiotonic Agents; Coronary Disease; Digoxin; Drug Interactions; Humans; Male; M | 1983 |
Comparative effects of verapamil, diltiazem, and nifedipine on hemodynamics and left ventricular function during acute myocardial ischemia in dogs.
Topics: Animals; Benzazepines; Blood Pressure; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Dose | 1984 |
Global ischemia in the immature canine ventricle. Enhanced protective effect of verapamil and potassium.
Topics: Animals; Cardiopulmonary Bypass; Coronary Circulation; Coronary Disease; Dogs; Heart Arrest, Induced | 1984 |
Acute coronary artery occlusion-reperfusion arrhythmias in pigs: antiarrhythmic and antifibrillatory evaluation of verapamil, nifedipine, prenylamine and propranolol.
Topics: Animals; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Blood Pressure; Calcium Channel Blockers | 1984 |
Evaluation of cardiac anoxia and ischemia models in the rat using calcium antagonists.
Topics: Adenine Nucleotides; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Corona | 1984 |
[Pharmacodynamic comparison of propranolol and verapamil in exertion stenocardia].
Topics: Adult; Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Exercise Test; Humans; M | 1984 |
An inhibitory effect of verapamil and diltiazem on the release of noradrenaline from ischaemic and reperfused hearts.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Coronary Disease; Diltiazem; Dopamine; Epinep | 1984 |
Prevention of reperfusion damage in working rat hearts by calcium antagonists and calmodulin antagonists.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Ch | 1984 |
Overdrive suppression of conduction in the canine His-Purkinje system after occlusion of the anterior septal artery.
Topics: Animals; Bundle of His; Cardiac Pacing, Artificial; Coronary Disease; Dogs; Heart Block; Heart Condu | 1984 |
Calcium antagonists and hypothermia: the temperature dependency of the negative inotropic and anti-ischemic properties of verapamil in the isolated rat heart.
Topics: Aerobiosis; Animals; Coronary Disease; Depression, Chemical; Drug Evaluation, Preclinical; Heart Arr | 1984 |
[Changes in left ventricular regional wall motion induced by Verapamil (author's transl)].
Topics: Arteriosclerosis; Calcium; Cineradiography; Coronary Disease; Heart Ventricles; Humans; Myocardial C | 1980 |
Pathophysiology and treatment of coronary arterial spasm.
Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Atropine; Calcium; Coronary Disease; Coronary Vess | 1980 |
Long-term prognosis of "variant" angina with medical treatment.
Topics: Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Arteriosclerosis; Coro | 1980 |
[Coronary spasms have been underrated: interview with A. Maseri].
Topics: Calcium; Coronary Disease; Nifedipine; Nitrates; Oxygen Consumption; Verapamil | 1980 |
[Hemodynamic and coronary effects of intravenous verapamil in coronary insufficiency].
Topics: Adult; Coronary Disease; Coronary Vessels; Female; Heart; Heart Atria; Hemodynamics; Humans; Injecti | 1981 |
Verapamil in the long-term treatment of angina pectoris.
Topics: Angina Pectoris; Bradycardia; Calcium Channel Blockers; Constipation; Coronary Disease; Dose-Respons | 1982 |
[Significance of transitory and asymptomatic ECG changes evaluated in a population of subjects with documented myocardial ischemia].
Topics: Angina Pectoris; Coronary Disease; Electrocardiography; Humans; Male; Middle Aged; Nitroglycerin; Ve | 1982 |
Sustained limitation of myocardial necrosis 24 hours after coronary artery occlusion: verapamil infusion in dogs with small myocardial infarcts.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; Male; Myocardial Infarc | 1983 |
Cellular electrophysiologic abnormalities of diseased human ventricular myocardium.
Topics: Action Potentials; Aged; Cardiac Pacing, Artificial; Coronary Disease; Electrophysiology; Heart Bloc | 1983 |
Calcium antagonists in heart failure.
Topics: Aortic Valve Insufficiency; Calcium Channel Blockers; Coronary Disease; Diltiazem; Heart Failure; He | 1983 |
Ischemia-reperfusion induced elevation of diastolic tension in the isolated guinea pig heart and the effects of calcium antagonists.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diastole; Diltiazem; Glyc | 1983 |
Calcium antagonistic activity and myocardial ischemic protection by both stereoisomers of verapamil.
Topics: Animals; Aorta; Calcium; Coronary Disease; Dose-Response Relationship, Drug; Gallopamil; Heart; Rabb | 1983 |
Prevention of certain biochemical changes in acute ischaemic rabbit heart by verapamil.
Topics: Animals; Coronary Disease; Energy Metabolism; Enzymes; Female; Lysosomes; Male; Myocardium; Rabbits; | 1983 |
Comparison of two calcium antagonists, verapamil and fendiline, in an experimental model of myocardial ischaemia mimicking classical angina on effort.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Disease; Dogs; Electrocardiography; Fem | 1983 |
Effects of calcium antagonists on the electrical alternans of the ST segment and on associated mechanical alternans during acute coronary occlusion in dogs.
Topics: Acute Disease; Animals; Arterial Occlusive Diseases; Calcium Channel Blockers; Coronary Disease; Dil | 1983 |
Enhanced myocardial protection with verapamil prior to postischemic reflow.
Topics: Animals; Coronary Circulation; Coronary Disease; Heart; Hypothermia, Induced; In Vitro Techniques; M | 1983 |
[Morphological bases of the effect of verapamil on the heart in experimental acute coronary failure].
Topics: Acute Disease; Animals; Coronary Disease; Drug Evaluation, Preclinical; Heart; Myocardial Infarction | 1983 |
[In vitro effect of verapamil on the function of isolated mitochondria of the rabbit heart perfused under conditions of aerobiosis, ischemia and reperfusion].
Topics: Aerobiosis; Animals; Calcium; Coronary Circulation; Coronary Disease; Male; Mitochondria, Heart; Per | 1982 |
Autoradiographic method for measuring the ischemic myocardium at risk: effects of verapamil on infarct size aftr experimental coronary artery occlusion.
Topics: Albumins; Animals; Autoradiography; Coronary Disease; Disease Models, Animal; Dogs; Myocardial Infar | 1980 |
The cardioprotective effect of verapamil.
Topics: Animals; Calcium Channel Blockers; Coronary Disease; Lipid Metabolism; Male; Mitochondria, Heart; My | 1982 |
[Myocardial damage caused by ischemia and/or re-perfusion in cardiac surgery: prevention and treatment with verapamil].
Topics: Adult; Cardiac Output, Low; Cardiac Surgical Procedures; Coronary Artery Bypass; Coronary Disease; F | 1981 |
The effects of calcium channel blocking agents on cardiovascular function.
Topics: Angina Pectoris; Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease | 1982 |
The effects of verapamil, quiescence, and cardioplegia on calcium exchange and mechanical function in ischemic rabbit myocardium.
Topics: Action Potentials; Animals; Blood Flow Velocity; Calcium; Coronary Disease; Electric Stimulation; Ex | 1982 |
The effects of intravenous verapamil on hemodynamic status of patients with coronary artery disease receiving propranolol.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Comb | 1982 |
Hemodynamic consequences of combined beta-adrenergic and slow calcium channel blockade in man.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Drug Therapy, Combination; Electrocardiography; Fema | 1982 |
Clinical characteristics of patients with variant angina complicated by myocardial infarction or death within 1 month.
Topics: Adult; Angina Pectoris, Variant; Coronary Disease; Coronary Vasospasm; Death, Sudden; Diltiazem; Ele | 1982 |
Suppression of ischemic related ventricular tachycardia by verapamil during treadmill exercise testing.
Topics: Adult; Angina Pectoris; Coronary Disease; Depression, Chemical; Electrocardiography; Exercise Test; | 1982 |
The effect of verapamil on myocardial ultrastructure during and following release of coronary artery occlusion.
Topics: Animals; Coronary Disease; Dogs; Microscopy, Electron; Mitochondria, Heart; Myocardium; Perfusion; T | 1982 |
Anti-arrhythmic agents in ischemic heart disease: supraventricular arrhythmias, digitalis toxicity and chronic stable ventricular ectopic beats.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Digitalis; Digoxin; Heart Vent | 1982 |
[Calcium blocking as a therapeutic principle].
Topics: Calcium Channel Blockers; Coronary Disease; Humans; Nifedipine; Verapamil | 1982 |
Effects of verapamil on conduction delay and potassium efflux induced by global ischemia in isolated rabbit hearts.
Topics: Animals; Coronary Disease; Electrophysiology; Female; Heart Conduction System; In Vitro Techniques; | 1982 |
Inhibition of platelet function of antiarrhythmic drugs, verapamil and disopyramide.
Topics: Adenosine Triphosphate; Arachidonic Acids; Blood Platelets; Coronary Disease; Disopyramide; Humans; | 1982 |
Pathophysiological concentrations of lysophosphatides and the slow response.
Topics: Action Potentials; Animals; Calcium; Cats; Coronary Disease; Glycerophosphates; Hydrogen-Ion Concent | 1982 |
Coronary vascular reactivity after acute myocardial ischemia.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Endothelium; Male; Muscle, Smooth, Vascular; | 1982 |
Verapamil versus propranolol for angina at rest.
Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Disease; Coronary Vasospasm; Ergonovine; Humans; | 1982 |
Pharmacologic assessment of the functional state in stenosed coronary circulation of the dog.
Topics: Animals; Arterial Occlusive Diseases; Catheterization; Coronary Circulation; Coronary Disease; Depre | 1982 |
[Verapamil therapy of ischemic alternating ST waves].
Topics: Animals; Coronary Disease; Dogs; Electrocardiography; Myocardial Contraction; Verapamil | 1982 |
[Hemodynamic and electrocardiographic effects of verapamil in ischemic cardiopathy].
Topics: Adult; Aged; Coronary Disease; Electrocardiography; Female; Hemodynamics; Humans; Male; Middle Aged; | 1981 |
[Influence of verapamil on the electrophysiologic and mechanical effects of ischemia and reperfusion].
Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Electrocardiography; Heart Rate; Perfusion; Verapam | 1982 |
Effect of verapamil on left ventricular isovolumic relaxation time and regional left ventricular filling in hypertrophic cardiomyopathy.
Topics: Adult; Blood Pressure; Cardiomyopathy, Hypertrophic; Coronary Disease; Diastole; Echocardiography; F | 1980 |
Effects of nicardipine, a new dihydropyridine vasodilator, on coronary circulation and ischemia-induced conduction delay in dogs.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Electrophysiology; Female; He | 1982 |
Effects of calcium antagonists and lidocaine on conduction delay induced by acute myocardial ischemia in dogs.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Coronary Disease; Diltiazem; Dogs; H | 1980 |
Influence of severity of ventricular dysfunction on hemodynamic responses to intravenously administered verapamil in ischemic heart disease.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Heart Ventricles; Hemodynamics; Huma | 1981 |
Changes in cardiovascular function induced by verapamil in healthy subjects and in patients with ischemic heart disease.
Topics: Adult; Aged; Cineangiography; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Myo | 1981 |
Effect of calcium antagonists on the electrical alternans of the ST segment during acute coronary occlusion in dogs.
Topics: Acute Disease; Animals; Calcium; Coronary Disease; Diltiazem; Dipyridamole; Dogs; Electrocardiograph | 1981 |
Reduction of exercise-induced ischemic regional myocardial dysfunction by verapamil in conscious dogs.
Topics: Animals; Blood Pressure; Cardiovascular System; Constriction, Pathologic; Coronary Disease; Dogs; Ex | 1981 |
Inhibitory effect of anoxia on reperfusion- and digitalis-induced ventricular tachyarrhythmias.
Topics: Animals; Coronary Disease; Guinea Pigs; Heart Ventricles; Hypoxia; Male; Medigoxin; Oxygen; Perfusio | 1981 |
[Steady state and time-dependent slowing and conduction in acute myocardial ischemia-effect of lidocaine and verapamil (author's transl)].
Topics: Animals; Coronary Disease; Dogs; Lidocaine; Myocardial Contraction; Time Factors; Verapamil | 1980 |
Blood flow in normal and acutely ischemic myocardium after verapamil, diltiazem and nisoldipine (Bay k 5552), a new dihydropyridine calcium antagonist.
Topics: Animals; Benzazepines; Calcium; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Female; Hem | 1981 |
[Effect of isoptin and its combination with strophanthin on collateral coronary circulation and systemic hemodynamics in acute myocardial ischemia].
Topics: Acute Disease; Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Dogs; Drug E | 1981 |
[Protection of ischemic myocardium by verapamil (author's transl)].
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Verapamil | 1981 |
Electrotonically mediated delayed conduction and reentry in relation to "slow responses" in mammalian ventricular conducting tissue.
Topics: Action Potentials; Animals; Coronary Disease; Dogs; Electricity; Female; Heart Block; Heart Conducti | 1981 |
Effects of calcium antagonists on the alternation of the ST-T complex and associated conduction abnormalities during coronary occlusion in dogs.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Coronary Disease; Diltiazem; Dipyridamole; Dog | 1981 |
Evaluation of effect of drugs on the exercise ECG.
Topics: Atenolol; Blood Pressure; Cardiovascular Agents; Coronary Disease; Electrocardiography; Exercise Tes | 1981 |
[Underlying mechanism of favorable effect of Ca++-antagonists on conduction delay observed in ischemic myocardium (author's transl)].
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Dog | 1981 |
Nickel is released from the ischemic myocardium and contracts coronary vessels by a Ca-dependent mechanism.
Topics: Animals; Calcium; Chlorides; Coronary Disease; Coronary Vessels; Dogs; Myocardium; Nickel; Rats; Vas | 1981 |
Comparative effects of verapamil and nifedipine on reactive hyperemia and ventricular arrhythmias during coronary artery reperfusion.
Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Femal | 1980 |
[Effect of verapamil on myocardial contractility in ischemic cardiopathy: indirect evaluation by the polycardiographic method].
Topics: Coronary Disease; Humans; Myocardial Contraction; Verapamil | 1981 |
[Arrhythmias of reperfusion in ischemic cardiopathy: clinical significance and therapeutic possibilities].
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Cats; Coronary Circulation; Coronary Disease; Electr | 1980 |
Effect of verapamil on regional coronary and myocardial perfusion during acute coronary occlusion.
Topics: Acute Disease; Animals; Arterial Occlusive Diseases; Blood Pressure; Coronary Circulation; Coronary | 1980 |
[The role of calcium antagonists in the treatment of arrhythmias in myocardial ischemia].
Topics: Adult; Aged; Arrhythmias, Cardiac; Calcium; Coronary Disease; Female; Humans; Male; Middle Aged; Ver | 1980 |
Exercise-induced S-T segment elevation in variant angina.
Topics: Ambulatory Care; Angina Pectoris; Angina Pectoris, Variant; Coronary Angiography; Coronary Disease; | 1980 |
[Anti-arrhythmic effectiveness of isoptin in ischemic heart disease in the middle-aged and elderly].
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Coronary Disease; Drug Evaluati | 1980 |
Effects of Ca2+ antagonism on energy metabolism: Ca2+ and heart function after ischemia.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Calcium; Coronary Disease; Heart; Male; Mitoch | 1980 |
Protective effect of verapamil on vulnerability to ventricular fibrillation during myocardial ischaemia and reperfusion.
Topics: Adrenergic Fibers; Animals; Coronary Disease; Dogs; Electric Stimulation; Female; Male; Norepinephri | 1980 |
Protective effect of pretreatment with verapamil, nifedipine and propranolol on mitochondrial function in the ischemic and reperfused myocardium.
Topics: Adenosine Triphosphate; Aerobiosis; Animals; Calcium; Coronary Disease; Male; Mitochondria, Heart; N | 1980 |
Exercise-induced coronary arterial spasm: angiographic demonstration, documentation of ischemia by myocardial scintigraphy and results of pharmacologic intervention.
Topics: Angina Pectoris, Variant; Coronary Disease; Exercise Test; Humans; Indomethacin; Male; Middle Aged; | 1980 |
Differing electrophysiologic effects of slow response inhibiting agents manganese and verapamil on ischemic, infarcted and normal tissue in situ.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Dogs; Heart Conduction System; Manganese; Myocardia | 1980 |
Antianginal and myocardial metabolic properties of verapamil in coronary artery disease.
Topics: Angina Pectoris; Calcium; Coronary Circulation; Coronary Disease; Electrocardiography; Hemodynamics; | 1980 |
The effect of verapamil on mechanical performance of acutely ischemic and reperfused myocardium in the conscious dog.
Topics: Acute Disease; Animals; Blood Pressure; Cardiac Output; Cardiac Pacing, Artificial; Coronary Circula | 1981 |
[Mitochondrial functionality and homeostasis of CA during experimental ischaemia. Protective action of verapamil (author's transl)].
Topics: Animals; Calcium; Coronary Disease; Homeostasis; Male; Mitochondria, Heart; Rabbits; Verapamil | 1980 |
Myocardial metabolism and anginal threshold in coronary disease after verapamil administration.
Topics: Angina Pectoris; Blood Pressure; Coronary Disease; Electrocardiography; Heart; Humans; Lactates; Mal | 1980 |
Left ventricular function in patients with coronary artery disease after verapamil administration.
Topics: Arteries; Blood Pressure; Coronary Disease; Heart; Heart Rate; Heart Ventricles; Humans; Vasodilatio | 1980 |
Effects of intravenously administered verapamil on hemodynamic variables and ventricular function in acute myocardial infarction.
Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Heart; Humans; Male; Middle Aged; Myocardial Infarc | 1980 |
Cardioprotective effects of calcium ion antagonists in myocardial ischemia.
Topics: Adenosine Triphosphate; Animals; Benzazepines; Biological Transport, Active; Calcium; Coronary Disea | 1980 |
Limb vasoconstriction after successful angioplasty of the left anterior descending coronary artery.
Topics: Adrenergic alpha-Antagonists; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Circadian Rh | 1995 |
An intravascular ultrasound study of the influence of angiotensin-converting enzyme inhibitors and calcium entry blockers on the development of cardiac allograft vasculopathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Coronary Disease; Dil | 1995 |
Clinical significance and predisposing factors to symptomatic bradycardia and hypotension after percutaneous transluminal coronary angioplasty.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Bradycardia; Coronary Dise | 1994 |
Frequency of presumed reentry with an excitable gap in sustained ventricular tachycardia unassociated with coronary artery disease.
Topics: Adolescent; Adult; Bundle of His; Bundle-Branch Block; Cardiac Pacing, Artificial; Cardiomyopathy, D | 1993 |
Calpain activity alters in rat myocardial subfractions after ischemia or reperfusion.
Topics: Animals; Calpain; Coronary Disease; Male; Myocardial Reperfusion; Myocardium; Proteins; Rats; Rats, | 1993 |
Effect of amiloride and selected analogues on postischemic recovery of cardiac contractile function.
Topics: Amiloride; Animals; Carrier Proteins; Coronary Disease; Creatine Kinase; Male; Myocardial Contractio | 1993 |
Failure of calcium channel blockers to improve ventricular relaxation in humans.
Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Cardiac Catheterization; Coronary Angiography; Co | 1993 |
Primary prevention in patients with coronary heart disease: the APSIS study.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Female; Hu | 1995 |
Failure of calcium channel blockade to reduce platelet-mediated cyclic flow variations in dogs with coronary stenosis and endothelial injury.
Topics: Animals; Aspirin; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Disea | 1995 |
Verapamil and angiotensin-converting enzyme inhibitors in patients with coronary artery disease and reduced left ventricular ejection fraction.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Coronary Disease; Drug Eva | 1996 |
Differential effect of selected antiarrhythmic drugs on coronary artery ligation-induced ventricular arrhythmias on the right or left sides.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Disease Models, Animal; Dogs; Female; Ligation; M | 1995 |
Coronary hemodynamics before and after rotational atherectomy with adjunctive balloon angioplasty.
Topics: Aged; Angioplasty, Balloon, Coronary; Atherectomy, Coronary; Blood Flow Velocity; Combined Modality | 1996 |
Cocktail attenuation of rotational ablation flow effects (CARAFE) study: pilot.
Topics: Aged; Anticoagulants; Atherectomy, Coronary; Cardiac Pacing, Artificial; Coronary Disease; Coronary | 1996 |
Calcium antagonists and prevention of ventricular fibrillation induced by transient or persistent ischemia.
Topics: Analysis of Variance; Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Disease; Electrop | 1997 |
Calcium channel blocking agents and risk of cancer in patients with coronary heart disease. Benzafibrate Infarction Prevention (BIP) Study Research Group.
Topics: Aged; Calcium Channel Blockers; Cause of Death; Confidence Intervals; Coronary Disease; Diltiazem; F | 1998 |
[KHK and treatment with calcium antagonists].
Topics: Calcium Channel Blockers; Coronary Disease; Heart Failure; Humans; Risk Factors; Vasodilator Agents; | 1996 |
Effect of diltiazem and verapamil on endothelin release by cultured human coronary smooth-muscle cells and endothelial cells.
Topics: Aged; Calcium Channel Blockers; Cells, Cultured; Coronary Disease; Coronary Vessels; Depression, Che | 1998 |
Adenosine in the diagnosis of wide complex tachycardias.
Topics: Adenosine; Aged; Atrial Fibrillation; Coronary Disease; Diagnosis, Differential; Digoxin; Electrocar | 1994 |
Coronary artery spasm after coronary artery bypass grafting.
Topics: Cardiac Catheterization; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Coronary Va | 1999 |
Hepatic failure in a patient taking rosiglitazone.
Topics: Aged; Combined Modality Therapy; Coronary Disease; Diabetes Mellitus, Type 2; Drug Interactions; Hum | 2000 |
Effect of verapamil on baroreflex sensitivity and on cardiovascular variability.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Autonomic Nervous System; Baroreflex; Blood P | 2000 |
[Accomplishing 2 goals at once. Nephropathy and cardiac risk].
Topics: Antihypertensive Agents; Coronary Disease; Diabetes Mellitus, Type 2; Drug Combinations; Humans; Hyp | 2000 |
[New strategies in the treatment of restenosis].
Topics: Angioplasty, Balloon, Coronary; Angioplasty, Balloon, Laser-Assisted; Anticholesteremic Agents; Athe | 2000 |
Refractory no-reflow successfully treated with local infusion of high-dose adenosine and verapamil--a case report.
Topics: Adenosine; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Coronary Angiography; Coronary C | 2001 |
Reversal of preexisting vasospasm in coronary artery conduits.
Topics: Arteries; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Culture Techniques; Di | 2001 |
[Conservative therapy of coronary disease].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; | 1976 |
[Therapy of coronary heart disease].
Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium; Coronary Disease; Humans; Isosorbide Dinitrate | 1977 |
Cellular calcium and cardiac cell death.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Calcium; Cell Membrane Permeability; Cell Survi | 1979 |
[Exertion-electrocardiographic and hemodynamic studies with oral verapamil in chronic ischemic heart disease].
Topics: Adult; Blood Pressure; Coronary Disease; Drug Evaluation; Electrocardiography; Female; Heart Rate; H | 1978 |
Treatment of Prinzmetal's angina due to coronary artery spasm using verapamil: a report of three cases.
Topics: Angina Pectoris; Angina Pectoris, Variant; Atropine; Coronary Disease; Electrocardiography; Heart Bl | 1978 |
The effect of verapamil on experimental myocardial ischaemia with a particular reference to regional myocardial blood flow and metabolism.
Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Ele | 1977 |
Reentrant ventricular arrhythmias in the late myocardial infarction period. 7. Effect of verapamil and D-600 and the role of the "slow channel".
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Coronary Disease; Dogs; Electrocardiography; Gallo | 1979 |
Electrocardiographic observations on the termination of supraventricular tachycardia by verapamil.
Topics: Adult; Aged; Coronary Disease; Depression, Chemical; Electrocardiography; Female; Heart Rate; Humans | 1979 |
[Effect of verapamil on the cycloergometric test in patients with coronary artery disease (complementary study)].
Topics: Blood Pressure; Coronary Disease; Exercise Test; Female; Humans; Male; Pulse; Verapamil | 1979 |
[Value of verapamil in long-term treatment of coronary disease, hypertension and functional disorders of the cardiovascular system].
Topics: Adult; Cardiovascular Diseases; Coronary Disease; Female; Humans; Hypertension; Male; Middle Aged; V | 1979 |
[Intravenous verapamil in the treatment of acute coronary insufficiency].
Topics: Acute Disease; Adult; Aged; Angina Pectoris; Coronary Disease; Female; Humans; Male; Middle Aged; My | 1979 |
[Hemodynamic action of verapamil: effect on preload, afterload and contractile state. Impact on ventricular performance].
Topics: Adolescent; Adult; Aorta; Blood Pressure; Child; Coronary Disease; Female; Heart Ventricles; Humans; | 1979 |
[Coronary disease and calcium antagonists].
Topics: Angina Pectoris; Calcium; Coronary Disease; Diltiazem; Humans; Nifedipine; Verapamil | 1979 |
[Echocardiography during exercise and coronary disease].
Topics: Aged; Coronary Disease; Echocardiography; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Mi | 1979 |
[Evaluation of the effect of verapamil on the tolerance for exertion in coronary patients].
Topics: Adult; Coronary Disease; Drug Evaluation; Exercise Test; Female; Humans; Male; Middle Aged; Physical | 1979 |
[Verapamil and ventricular arrhythmias: interference with the ventricular recovery phase].
Topics: Adult; Arrhythmias, Cardiac; Coronary Disease; Humans; Male; Middle Aged; Pulmonary Heart Disease; S | 1979 |
Effects of dilazep (AS-05) on human blood platelet aggregation.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Azepines; Coronary Disease; Dilazep; Female; Humans; | 1979 |
Effect of verapamil and nifedipine on ischemic myocardial metabolism in dogs.
Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Female; Glycogen; Heart Rate; Lactates; Male; Myoca | 1979 |
Effects of verapamil on ventricular rhythm during acute coronary occlusion.
Topics: Animals; Coronary Disease; Dogs; Heart Conduction System; Heart Rate; Heart Ventricles; Ventricular | 1978 |
Initial myocardial adjustments to brief periods of ischemia and reperfusion in the conscious dog.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Chemotherapy, Cancer, Regional Perfusion; Coronary Dis | 1978 |
[Hemodynamic effects of verapamil in patients with coronary insufficiency].
Topics: Adult; Aged; Blood Pressure; Cineangiography; Coronary Disease; Electrocardiography; Female; Heart R | 1978 |
[Comparative study of the medium term use of verapamil and perhexiline in the treatment of chronic coronary insufficiency. Clinical and cycloergometric evaluation].
Topics: Adult; Aged; Chronic Disease; Coronary Disease; Electrocardiography; Exercise Test; Female; Humans; | 1978 |
Effect of verapamil on coronary hemodynamics in patients with coronary heart disease.
Topics: Blood Pressure; Cardiac Output; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; | 1978 |
The effect of verapamil, isoproterenol, and dexamethasone on enzyme release and viability of coronary obstructed guinea-pig hearts.
Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Creatine Kinase; Dexamethason | 1978 |
[Calcium antagonists in cardiologic therapy].
Topics: Calcium; Coronary Disease; Heart Diseases; Humans; Nifedipine; Pyridines; Sodium; Verapamil | 1978 |
[Calcium antagonists in cardiologic therapy].
Topics: Calcium; Coronary Disease; Heart Diseases; Humans; Myocardium; Nifedipine; Pyridines; Verapamil | 1978 |
Electrophysiological effects of verapamil.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Dogs; Electrophysiology; Heart; Heart Conduction Sy | 1978 |
[Pharmacological assumptions in the use of calcium antagonists].
Topics: Arrhythmias, Cardiac; Calcium; Coronary Disease; Heart Diseases; Humans; Nifedipine; Pyridines; Vera | 1978 |
[Calcium antagonists in acute coronary insufficiency].
Topics: Acute Disease; Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Calcium; Coronary Disease; Female | 1978 |
[Hemodynamic evaluation of the action of calcium antagonists].
Topics: Adult; Blood Pressure; Calcium; Cardiac Output; Coronary Circulation; Coronary Disease; Female; Hear | 1978 |
Reduction in infarct size following experimental coronary occlusion by administration of verapamil.
Topics: Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Disease; Disease Models, Ani | 1975 |
Effect of the calcium antagonist verapamil on necrosis following temporary coronary artery occlusion in dogs.
Topics: Animals; Calcium; Coronary Disease; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclin | 1977 |
Effect of drugs on conduction delay and incidence of ventricular arrhythmias induced by acute coronary occlusion in dogs.
Topics: Animals; Aprindine; Arrhythmias, Cardiac; Coronary Disease; Disease Models, Animal; Dogs; Heart Cond | 1977 |
[Verapamil in a single dose, evaluation by means of the ergometric test].
Topics: Administration, Oral; Adult; Coronary Disease; Drug Evaluation; Female; Heart Function Tests; Hemody | 1977 |
Action of verapamil on the sinus node recovery time and AV conduction studied by His bundle recordings.
Topics: Adolescent; Adult; Bundle of His; Coronary Disease; Electrocardiography; Heart Diseases; Heart Rate; | 1977 |
[Long-term administration of verapamil in coronary disease].
Topics: Adult; Aged; Coronary Disease; Drug Tolerance; Female; Humans; Male; Middle Aged; Time Factors; Vera | 1977 |
Regional contractility. Selective depression of ischemic myocardium by verapamil.
Topics: Animals; Coronary Disease; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Female; Hea | 1976 |
Effects of verapamil on regional myocardial blood flow and ST segment. Role of the induced bradycardia.
Topics: Animals; Blood Pressure; Bradycardia; Coronary Circulation; Coronary Disease; Disease Models, Animal | 1976 |
[Effect of verapamil on left ventricular contraction in patients with coronary disease].
Topics: Adult; Coronary Disease; Drug Evaluation; Heart Ventricles; Humans; Middle Aged; Myocardial Contract | 1976 |
[Action of verapamil in coronariopathic patients. Evaluation using the ergometric test].
Topics: Adult; Aged; Arteriosclerosis; Coronary Disease; Coronary Vessels; Drug Evaluation; Female; Heart Fu | 1976 |
[Clinical results with verapamil in intravenous administration in the emergency therapy of cardiac arrhythmias].
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Coronary Disease; Female; Heart | 1975 |
[Assessment of therapeutic effects of Verapamil by means of an exercise test].
Topics: Adult; Coronary Disease; Drug Evaluation; Exercise Test; Humans; Middle Aged; Verapamil | 1975 |
[Reduction of acute myocardial ischemia with verapamil. Evaluation by epicardial mapping].
Topics: Coronary Disease; Drug Evaluation; Electrocardiography; Verapamil | 1975 |
[Influence of anti-arrhythmia agents on electrolyte metabolism].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Disease; Female; Gallopamil; Humans; Hypertension; Mal | 1976 |
Use of cell culture for optimisation of direct antiatherogenic therapy with verapamil.
Topics: Administration, Oral; Aorta; Arteriosclerosis; Cells, Cultured; Cholesterol; Coronary Disease; Human | 1992 |
Lack of effect of chronic calcium antagonist treatment on beta 1- and beta 2-adrenoceptors in right atria from patients with or without heart failure.
Topics: Adult; Aged; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Diltiazem; Female; | 1992 |
Positive chronotropic responses induced by alpha 1-adrenergic stimulation of normal and "ischemic" Purkinje fibers have different receptor-effector coupling mechanisms.
Topics: Action Potentials; Animals; Calcium; Coronary Disease; Dioxanes; Dogs; GTP-Binding Proteins; Homeost | 1992 |
[Therapy of coronary disease].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Aspirin; Calcium Channel Blockers; Clinical Trials as | 1992 |
The molecular basis for the use of calcium antagonists in ischaemic heart disease.
Topics: Adenosine Triphosphate; Animals; Calcium; Coronary Disease; Magnetic Resonance Spectroscopy; Male; M | 1992 |
Epicardial controlled-release verapamil prevents ventricular tachycardia episodes induced by acute ischemia in a canine model.
Topics: Animals; Coronary Disease; Delayed-Action Preparations; Disease Models, Animal; Dogs; Dose-Response | 1992 |
Age-related effects of ischemia, lidocaine and verapamil on overdrive-induced suppression of ventricular pacemakers in isolated rat heart.
Topics: Aging; Animals; Coronary Disease; In Vitro Techniques; Lidocaine; Male; Rats; Rats, Inbred Strains; | 1992 |
[Are all calcium antagonists alike?].
Topics: Calcium Channel Blockers; Coronary Disease; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1992 |
Adverse effect of verapamil in myasthenia gravis.
Topics: Contraindications; Coronary Artery Bypass; Coronary Disease; Electromyography; Humans; Male; Middle | 1992 |
Mechanisms of transient augmentation of myocardial contraction after a brief coronary occlusion.
Topics: Animals; Calcium; Catecholamines; Constriction; Coronary Circulation; Coronary Disease; Dogs; Hemody | 1992 |
[The effect of verapamil on left ventricular diastolic function in coronary heart disease].
Topics: Adult; Aged; Cardiac Volume; Coronary Disease; Diastole; Dose-Response Relationship, Drug; Drug Eval | 1992 |
Ventricular tachycardia of right bundle-branch block--left axis deviation morphology and organic heart disease.
Topics: Adolescent; Aged; Bundle of His; Bundle-Branch Block; Cardiac Pacing, Artificial; Combined Modality | 1992 |
Postischaemic hypercontraction is enhanced in ischaemically injured canine myocardium.
Topics: Animals; Calcium; Coronary Disease; Disease Models, Animal; Dogs; Myocardial Contraction; Myocardial | 1992 |
[Effects of calcium antagonists on functional properties of monocytes in patients with ischemic heart disease].
Topics: Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Cyclic AMP; Humans; In Vitro Techniques | 1991 |
Protective effects of R 56 865 against ischemic damage in the isolated rabbit heart.
Topics: Animals; Benzothiazoles; Calcium; Calcium Channels; Cell Death; Coronary Disease; Female; Hemodynami | 1991 |
Effects of nisoldipine on the no-reflow phenomenon in globally ischemic rat hearts.
Topics: Analysis of Variance; Animals; Coronary Circulation; Coronary Disease; Energy Metabolism; In Vitro T | 1990 |
Determinants of acute hemodynamic and electrophysiologic effects of verapamil in humans: role of myocardial drug uptake.
Topics: Adult; Aged; Analysis of Variance; Cardiac Catheterization; Clinical Trials as Topic; Coronary Disea | 1990 |
Evidence for a link between mechanical and electrical alternans in acutely ischaemic myocardium of anaesthetized dogs.
Topics: Animals; Calcium Channel Blockers; Cardiac Complexes, Premature; Coronary Disease; Diltiazem; Dogs; | 1991 |
[A chromatographic method of determining verapamil and norverapamil in blood plasma].
Topics: Chromatography, Liquid; Coronary Disease; Humans; Verapamil | 1991 |
Comparison of the effects of carvedilol, propranolol, and verapamil on in vitro platelet function in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Blood Platelets; Carbazoles; Carvedilol; Coronary Disease; Cyclic AMP; | 1991 |
Cardioprotective aspects of calcium antagonists.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Cytosol; Male; | 1991 |
Programmed electrical stimulation and drugs identify two subgroups of ventricular tachycardias occurring 16-24 hours after occlusion of the left anterior descending artery.
Topics: Animals; Arterial Occlusive Diseases; Cardiac Pacing, Artificial; Coronary Disease; Dogs; Electrocar | 1992 |
Myocardial protection with verapamil during ischaemia and reperfusion: dissociation between myocardial salvage and the degree of ATP depletion during ischaemia.
Topics: Adenosine Triphosphate; Animals; Calcium; Coronary Circulation; Coronary Disease; Female; Hemodynami | 1991 |
End systolic pressure-length relations in halothane anaesthetised dogs: effects of regional ischaemia and inotropic agents.
Topics: Anesthesia; Animals; Calcium; Coronary Disease; Dogs; Female; Halothane; Male; Myocardial Contractio | 1991 |
Protection against ischaemic ventricular fibrillation by blocking agents of myocardial cell calcium influx. Electrophysiological study in the pig in situ heart.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Electrophysiology; Myocardi | 1991 |
[Effects of verapamil on the functional state of the liver in ischemic heart disease].
Topics: Adult; Coronary Disease; Humans; Liver; Liver Function Tests; Male; Middle Aged; Time Factors; Verap | 1991 |
[Characteristics of the treatment of ischemic heart disease with delayed-action verapamil].
Topics: Adult; Coronary Disease; Delayed-Action Preparations; Hematologic Tests; Hemostasis; Humans; Male; M | 1991 |
[Effects of calcium antagonists on the pattern of intracardiac hemodynamics and functional state of the myocardium in patients with angina pectoris relapsing after aortocoronary bypass operation].
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Hemodyna | 1991 |
The effects of calcium antagonists on extracellular potassium accumulation during global ischaemia in isolated perfused rat hearts.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Electrodes; Ex | 1991 |
Acute effects of commonly used drugs in the cardiac care unit on the myocardial extraction kinetics of 99mTc-Sestamibi.
Topics: Animals; Coronary Care Units; Coronary Disease; Digoxin; Dipyridamole; Drug Interactions; Guinea Pig | 1991 |
[Left ventricular hypertrophy as an indication for the prescribing of calcium antagonists in patients with ischemic heart disease].
Topics: Adult; Calcium Channel Blockers; Cardiomegaly; Coronary Disease; Drug Evaluation; Hemodynamics; Huma | 1991 |
Effect of cicletanine on overpacing-induced ST-segment elevation in conscious rabbits. A comparison with verapamil.
Topics: Animals; Blood Pressure; Consciousness; Coronary Disease; Diuretics; Electrocardiography; Electrophy | 1991 |
Drug effects on myocardial ischemia- and reperfusion-induced arrhythmias in anesthetized rats.
Topics: Animals; Arrhythmias, Cardiac; Aspirin; Coronary Disease; Male; Mannitol; Myocardial Reperfusion Inj | 1991 |
Three-year mortality in patients suspected of acute myocardial infarction with and without confirmed diagnosis. The Danish Study Group on Verapamil in Myocardial Infarction.
Topics: Age Factors; Coronary Disease; Denmark; Humans; Myocardial Infarction; Prospective Studies; Sex Fact | 1991 |
Relationship between systemic and coronary vascular responses to digoxin and concurrent drug therapy with verapamil/beta-adrenoceptor antagonists in humans.
Topics: Adrenergic beta-Antagonists; Adult; Cardiac Catheterization; Coronary Disease; Coronary Vessels; Dig | 1990 |
[Beta-adrenoblockaders and calcium antagonists in the treatment of patients with ischemic heart disease combined with hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Calcium Channel Blockers; Coronary Disease; Drug Ev | 1990 |
Magnitude and time course of extracellular potassium inhomogeneities during acute ischemia in pigs. Effect of verapamil.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Electrodes, Implanted; Female; Male; Myocardium; Po | 1991 |
Dose-related effects of isoflurane associated with low plasma concentrations of verapamil on global and regional function in normal and compromised canine myocardium.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Dose- | 1991 |
[Cardil (diltiazem) in the treatment of patients with ischemic heart disease and hypertension].
Topics: Coronary Disease; Diltiazem; Drug Evaluation; Hemodynamics; Humans; Hypertension; Nifedipine; Verapa | 1990 |
Determination of the extent of ischemic damage and the effect of the calcium antagonist, verapamil following coronary artery ligation in the rat.
Topics: Animals; Calcium; Constriction; Coronary Disease; Creatine Kinase; L-Lactate Dehydrogenase; Male; My | 1990 |
Antiischemic effect of trimetazidine: enzymatic and electric response in a model of in-vitro myocardial ischemia.
Topics: Animals; Cell Survival; Coronary Disease; Creatine Kinase; Diltiazem; Glyoxylates; Guinea Pigs; In V | 1990 |
[Protective effect of 2-[p-(dimethylamino) styryl] pyridine methiodide (DSPM) on acute experimental myocardial ischemia].
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Female; Heart Ra | 1990 |
[Therapy of perioperative myocardial damage in aortocoronary venous bypass surgery].
Topics: Cardiac Output, Low; Coronary Artery Bypass; Coronary Disease; Dopamine; Electrocardiography; Epinep | 1990 |
Calcium inhibition of glycolysis contributes to ischaemic injury.
Topics: Animals; Calcium; Coronary Disease; Glycolysis; Hypertension; In Vitro Techniques; Myocardial Reperf | 1990 |
[Changes in the indicators of intracardiac hemodynamics in patients with post-infarction cardiosclerosis under the action of verapamil].
Topics: Cardiomegaly; Coronary Disease; Heart; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contracti | 1990 |
Protective effect of verapamil in ischemic porcine hearts: analysis of ultrastructural and metabolic changes using in vivo 31P-NMR spectroscopy.
Topics: Angiography; Animals; Autopsy; Coronary Disease; Heart; Hemodynamics; Hydrogen-Ion Concentration; Ma | 1990 |
[The use of verapamil in suppositories for treating patients with ischemic heart disease].
Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Coronary Disease; Drug Evaluation; Female; Hemodynamics | 1990 |
Specific bradycardic agents. 1. Chemistry, pharmacology, and structure-activity relationships of substituted benzazepinones, a-new class of compounds exerting antiischemic properties.
Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Calcium Channel Blockers; Cardiovascular Agents; Chem | 1990 |
Very early prediction of restenosis after successful coronary angioplasty: anatomic and functional assessment.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Coronary Disease; Differential Threshold; Exercise Test | 1990 |
Calcium antagonists show two modes of protection in ischemic heart failure.
Topics: Animals; Bepridil; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diastole; Dose- | 1990 |
[The use of propranolol and verapamil in patients with ischemic heart disease].
Topics: Adult; Arrhythmias, Cardiac; Chronic Disease; Coronary Disease; Drug Evaluation; Female; Heart Failu | 1990 |
[Effect of the intravenous administration of finoptin on coronary venous blood flow in patients with ischemic heart disease].
Topics: Coronary Circulation; Coronary Disease; Coronary Vessels; Hemodynamics; Humans; Injections, Intraven | 1990 |
Interaction between calcium channel blockers and volatile anaesthetics in the rat heart-lung preparation.
Topics: Anesthetics; Animals; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Interactions; Enfl | 1990 |
The effect of calcium antagonists on the activities of lipid metabolizing enzymes in the isolated ischaemically perfused and reperfused rat heart.
Topics: Acyltransferases; Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Glycerol- | 1990 |
Pharmacologic effects on coronary microvessels during myocardial ischaemia.
Topics: Animals; Blood Flow Velocity; Capillary Permeability; Coronary Circulation; Coronary Disease; Corona | 1990 |
Mechanical activity of the ischaemic myocardium as affected by verapamil and fendiline.
Topics: Animals; Coronary Disease; Electric Stimulation; Fendiline; Heart; In Vitro Techniques; Myocardial C | 1990 |
[Effect of verapamil on the molecular characteristics of myocardial actomyosin in experimental ischemia].
Topics: Actomyosin; Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Chemical Phenomena; Chemistry, Physical; Coronar | 1986 |
The influence of verapamil and its isomers on vulnerability to ventricular fibrillation during acute myocardial ischemia and adrenergic stimulation in isolated rat heart.
Topics: Animals; Calcium; Coronary Disease; Cyclic AMP; Epinephrine; In Vitro Techniques; Ion Channels; Male | 1986 |
Concentration-dependent effects of prostacyclin on the response of the isolated guinea pig heart to ischemia and reperfusion: possible involvement of the slow inward current.
Topics: Animals; Calcium; Coronary Disease; Epoprostenol; Guinea Pigs; Heart Conduction System; Heart Rate; | 1987 |
Effects of (-), (+/- ), and (+) verapamil on coronary occlusion-induced mortality and infarct size.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Male; Myocardial Infarction; Rats; Rats, Inbred Str | 1987 |
Examination of the direct effects of nicorandil, verapamil, propranolol, and nitroglycerin on the hypoxic canine myocardium.
Topics: Animals; Coronary Disease; Dogs; Female; Hemodynamics; In Vitro Techniques; Male; Myocardium; Niacin | 1987 |
Epicardial electrical activation analyzed via frequency-wavenumber spectrum estimation for the characterization of arrhythmiagenic states.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Coronary Disease; Coronary Vessels; Digoxin; Dogs; Electroca | 1987 |
Effect of digoxin on the extent of injury and the severity of arrhythmias during acute myocardial ischemia and infarction in the dog.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Digoxin; Dogs; Electrocardiography; Heart Rate; Hea | 1988 |
Modulation of conduction slowing in ischemic rabbit myocardium by calcium-channel activation and blockade.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
Dissociation of cardiodepression from cardioprotection with calcium antagonists: diltiazem protects ischemic rat myocardium with a lower functional cost as compared with verapamil or nifedipine.
Topics: Animals; Calcium; Calcium Chloride; Coronary Circulation; Coronary Disease; Diltiazem; Heart; Heart | 1989 |
Effects of Ro 40-5967, a novel calcium antagonist, on myocardial function during ischemia induced by lowering coronary perfusion pressure in dogs: comparison with verapamil.
Topics: Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Coronary Di | 1989 |
Prolonged protective effect of the calcium antagonist anipamil on the ischemic reperfused rabbit myocardium: comparison with verapamil.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Creatin | 1989 |
Mechanism of membrane phospholipid degradation in ischemic-reperfused rat hearts.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Coronary Disease; Fatty Acids, Nonesterified; | 1989 |
Laser backscatter studies of intracellular Ca2+ oscillations in isolated hearts.
Topics: Animals; Calcium; Coronary Disease; Egtazic Acid; Heart; In Vitro Techniques; Lasers; Myocardial Rep | 1989 |
[Exercise capacity of coronary heart disease patients in long-term follow-up with gallopamil in comparison with premedication with verapamil].
Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; Exercise Test; F | 1989 |
A hemodynamic comparison of verapamil, diltiazem, and amlodipine in coronary artery disease.
Topics: Amlodipine; Calcium Channel Blockers; Coronary Disease; Diltiazem; Female; Hemodynamics; Humans; Mal | 1989 |
[Hemodynamic and medicamentous modification of stimulated atrial natriuretic factor secretion].
Topics: Adult; Aged; Atenolol; Atrial Natriuretic Factor; Blood Pressure; Cardiac Catheterization; Cardiac P | 1989 |
Effect of calcium entry and beta blockade during infrarenal aortic clamping.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Aorta, Abdominal; Calcium Channel Blocke | 1989 |
Effects of verapamil and propranolol on changes in extracellular K+, pH, and local activation during graded coronary flow in the pig.
Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disea | 1989 |
[Drugs in secondary prevention of ischemic heart disease: achievements, problems and prospects].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Female; Humans; Isosorbide | 1989 |
[New approach to the development of Ca antagonists].
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; Humans; Hypertension; Nic | 1989 |
[Combination therapy with isosorbide dinitrate and verapamil in patients with coronary heart disease and hypertension: effect on blood pressure, ischemia and left ventricular function].
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Disease | 1989 |
Effects of hypoxia, elevated K+ and acidosis on the potency of verapamil, diltiazem and nifedipine in the guinea-pig isolated papillary muscle.
Topics: Acidosis; Animals; Cell Hypoxia; Coronary Disease; Diltiazem; Dinitrophenols; Electric Stimulation; | 1989 |
Metabolic protection by verapamil during graded coronary flow reduction independent of effect on baseline systolic function. Separation of mechanical and ionic markers of ischemia.
Topics: Animals; Coronary Circulation; Coronary Disease; Dobutamine; Myocardial Contraction; Myocardium; Pot | 1989 |
Effects of calcium antagonists and free radical scavengers on myocardial ischemia and reperfusion injury: evaluation by 31P-NMR spectroscopy.
Topics: Adenosine; Adenosine Triphosphate; Animals; Catalase; Coronary Disease; Heart; In Vitro Techniques; | 1989 |
[Prevention of tachycardia induced by a fentanyl-pancuronium combination in the coronary patient: propranolol or verapamil?].
Topics: Coronary Disease; Fentanyl; Humans; Middle Aged; Pancuronium; Propranolol; Tachycardia; Verapamil | 1989 |
[Nifedipine and verapamil in the treatment of ischemic heart disease and hypertension].
Topics: Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Humans; Hypertension; Nifedipin | 1989 |
The effect of verapamil in patients with asymptomatic stress-induced ischemia.
Topics: Adult; Aged; Coronary Disease; Electrocardiography; Exercise Test; Female; Hemodynamics; Humans; Mal | 1989 |
Hemodynamic benefits of verapamil after aortic reconstruction.
Topics: Aged; Aorta, Abdominal; Blood Pressure; Coronary Disease; Heart Rate; Hemodynamics; Humans; Middle A | 1989 |
[Effect of verapamil on the functional status of thrombocytes in patients with ischemic heart disease].
Topics: Adult; Aged; Blood Platelets; Coronary Disease; Female; Humans; In Vitro Techniques; Male; Malondial | 1989 |
Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists.
Topics: Animals; Arrhythmias, Cardiac; Consciousness; Coronary Disease; Diltiazem; Electrocardiography; Hear | 1989 |
Myocardial stunning in hypertrophic cardiomyopathy: recovery predicted by single photon emission computed tomographic thallium-201 scintigraphy.
Topics: Adult; Cardiomyopathy, Hypertrophic; Coronary Disease; Female; Heart; Humans; Myocardial Contraction | 1989 |
Verapamil prevents silent myocardial perfusion abnormalities during exercise in asymptomatic patients with hypertrophic cardiomyopathy.
Topics: Adult; Cardiomyopathy, Hypertrophic; Coronary Circulation; Coronary Disease; Echocardiography; Exerc | 1989 |
Serum binding of nifedipine and verapamil in patients with ischaemic heart disease on monotherapy.
Topics: Adult; Blood Proteins; Coronary Disease; Dialysis; Humans; Male; Middle Aged; Nifedipine; Protein Bi | 1989 |
[Morphofunctional analysis of the efficacy of verapamil in experimental ischemia].
Topics: Animals; Coronary Disease; Dogs; Drug Evaluation, Preclinical; Myocardial Contraction; Myocardial Re | 1989 |
Effects of verapamil on ischaemia-induced impairment of ATP-dependent calcium extrusion in rat heart sarcolemma.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Radioisotopes; Coronary Disease; In Vitro Techniqu | 1989 |
[Effect of isoptin on catecholamine levels in arterial and coronary venous blood during an attack of myocardial ischemia].
Topics: Adult; Arteries; Coronary Disease; Coronary Vessels; Dopamine; Epinephrine; Humans; Male; Middle Age | 1989 |
Effect of verapamil on canine left ventricular function in the presence of fentanyl when apical blood flow is critically limited.
Topics: Anesthesia, Intravenous; Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Fentanyl; He | 1989 |
Verapamil impairs secretion of stimulated atrial natriuretic factor in humans.
Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Coronary Disease; Cyclic GMP; Female; Heart | 1988 |
Effect of ischemia on calcium-dependent fluorescence transients in rabbit hearts containing indo 1. Correlation with monophasic action potentials and contraction.
Topics: Action Potentials; Animals; Calcium; Calcium Channels; Coronary Disease; Fluorescence; Fluorescent D | 1988 |
Clinical pharmacology of vasodilator drugs.
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Coronary Disease; Humans; Hydralazine; Hyper | 1985 |
[Antiaggregants of thrombocytes in ischemic heart disease].
Topics: Adrenergic beta-Antagonists; Aspirin; Coronary Disease; Dipyridamole; Fibrinolytic Agents; Humans; M | 1985 |
Clinical and research applications of ambulatory Holter ST-segment and heart rate monitoring.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angina Pectoris, Variant; Blood Pressure; Corona | 1986 |
Verapamil in angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Disease; Hemodynamics; Humans; Verapamil | 1986 |
Contrasting effects of verapamil and nifedipine on pH of ischemic myocardium in the dog.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Hydrogen-Ion Concentration; Myo | 1989 |
Cardioprotection by the calcium antagonist PN 200-110 in the absence and presence of cardiodepression.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; In Vitro Techn | 1985 |
[Effects of trimetazidine on a model of in vitro myocardial ischemia].
Topics: Animals; Coronary Circulation; Coronary Disease; Creatine Kinase; Diltiazem; Electrocardiography; Gu | 1986 |
Electrophysiological study on hypertrophied and ischemic myocardial of rats.
Topics: Action Potentials; Animals; Calcium; Cardiomegaly; Coronary Disease; Electrophysiology; Female; Lana | 1987 |
[Acute coronary occlusion during transluminal angioplasty: role of coronary thrombosis].
Topics: Aged; Angiography; Angioplasty, Balloon; Coronary Angiography; Coronary Disease; Coronary Thrombosis | 1988 |
The effect of verapamil on ischaemia-induced changes to the sarcolemma.
Topics: 5'-Nucleotidase; Animals; Biological Transport; Calcium; Coronary Disease; Male; Myocardium; Nucleot | 1985 |
Protective effects of the calmodulin antagonist bepridil on ischaemia induced in the rat myocardium.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Bepridil; Calmodulin; Coronary Disease; Drug In | 1986 |
Effects of bepridil on regional myocardial ischemia and comparison with verapamil.
Topics: Animals; Bepridil; Calcium Channel Blockers; Carbon Dioxide; Coronary Circulation; Coronary Disease; | 1986 |
Dose-response scrutiny of coronary vasodilation after intracoronary verapamil in man. A quantitative cineangiographic study.
Topics: Adult; Angina Pectoris; Cineangiography; Coronary Circulation; Coronary Disease; Coronary Vessels; D | 1986 |
Effects of verapamil and timolol on cellular morphometric changes in cat hearts with regional ischaemia.
Topics: Animals; Cats; Coronary Disease; Female; Heart; Hemodynamics; Male; Timolol; Verapamil | 1988 |
Limitation of myocardial necrosis with verapamil during sustained coronary occlusion in the closed-chest dog.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Heart Diseases; Male; Necrosis; Verapamil | 1988 |
Angiographic changes thirty minutes following percutaneous transluminal coronary angioplasty.
Topics: Adult; Aged; Angioplasty, Balloon; Cineangiography; Coronary Angiography; Coronary Disease; Female; | 1985 |
[Metabolism of the ischemic heart muscle and the effect of reperfusion and verapamil].
Topics: Animals; Coronary Disease; Heart; Humans; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myo | 1988 |
The effect of verapamil cardioplegia on myocardial ultrastructure.
Topics: Biopsy; Cardioplegic Solutions; Coronary Disease; Heart; Humans; Male; Myocardium; Potassium; Verapa | 1988 |
Ventricular fibrillation in acute experimental myocardial ischemia: protection by magnesium sulfate.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Coronary Disease; Dogs; Hemodynamics; Magnesi | 1988 |
Quantification of arrhythmias using scoring systems: an examination of seven scores in an in vivo model of regional myocardial ischaemia.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Disease Models, Animal; Dose-Response Relationship, | 1988 |
[Cardioprotective effects of verapamil on mitochondrial function in the ischemic myocardium].
Topics: Animals; Coronary Disease; Male; Mitochondria, Heart; Oxidative Phosphorylation; Rabbits; Verapamil | 1988 |
[Withdrawal syndrome after discontinuation of calcium channel blockers].
Topics: Coronary Disease; Coronary Vasospasm; Humans; Nifedipine; Substance Withdrawal Syndrome; Verapamil | 1988 |
Effects of intravenous verapamil on left ventricular systolic function and diastolic filling dynamics in patients with coronary artery disease: analysis of intramyocardial markers.
Topics: Aged; Cardiac Catheterization; Cineangiography; Coronary Artery Bypass; Coronary Disease; Humans; Ma | 1988 |
[Coronary spasm immediately following coronary revascularization].
Topics: Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Coronary Vasospasm; Coronary Vessels | 1988 |
[Effect of verapamil on blood viscosity in ischemic heart disease].
Topics: Adult; Blood Viscosity; Coronary Disease; Erythrocyte Deformability; Humans; In Vitro Techniques; Ma | 1987 |
Influence of verapamil and its combination with glucose-insulin-potassium-infusion on acute myocardial ischemia in dogs.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardioplegic Solutions; Coronary Disease; Dogs; Dru | 1987 |
Reversal of ST depression and low maximal oxygen uptake after verapamil with normal coronary arteries and pulmonary disease.
Topics: Administration, Oral; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; Exercise Test; Hu | 1988 |
[The protective effect of verapamil on the heart muscle during reperfusion].
Topics: Animals; Coronary Circulation; Coronary Disease; Male; Mitochondria, Heart; Oxidative Phosphorylatio | 1988 |
Effects of intracoronary verapamil administration in a sheep model of acute myocardial ischemia and reperfusion.
Topics: Acute Disease; Animals; Coronary Circulation; Coronary Disease; Creatine Kinase; Hemodynamics; Injec | 1988 |
[Effect of finoptin on cerebrocardiac correlations in atherosclerotic circulatory encephalopathy in patients with ischemic heart disease].
Topics: Adult; Brain; Coronary Disease; Drug Evaluation; Heart; Hemodynamics; Humans; Intracranial Arteriosc | 1988 |
[The protective effect of verapamil on the ischemic myocardium].
Topics: Animals; Coronary Disease; Male; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; | 1988 |
The insufficient nitrate response: patients' characterization and response to beta and calcium blockade.
Topics: Adult; Aged; Coronary Disease; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Elec | 1988 |
[Prevention of ischemic and reperfusion arrhythmias using the calmodulin blocker trifluoperazine].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calmodulin; Coronary Disease; In Vitro Techni | 1988 |
[Combined obzidan and verapamil treatment of ischemic heart disease patients].
Topics: Chronic Disease; Coronary Disease; Drug Evaluation; Drug Therapy, Combination; Exercise Test; Hemody | 1987 |
Ion shifts in myocardial cells during ischemia and reperfusion and the effect of membrane stabilizing agents on ischemic ion transport.
Topics: Animals; Biological Transport, Active; Calcium; Cations; Cell Membrane Permeability; Coronary Diseas | 1987 |
Verapamil in a new model of severe local myocardial ischaemia due to combined coronary occlusion and stenosis.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Electro | 1987 |
Early intraneuronal mobilization and deamination of noradrenaline during global ischemia in the isolated perfused rat heart.
Topics: Animals; Calcium; Coronary Circulation; Coronary Disease; Deamination; Desipramine; Heart; In Vitro | 1987 |
[Non-obstructive hypertrophic cardiomyopathy and systolic compression of 3 coronary arteries. Long-term improvement with verapamil].
Topics: Adult; Cardiomyopathy, Hypertrophic; Constriction, Pathologic; Coronary Disease; Echocardiography; E | 1987 |
Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Dogs; Female; Heart Conduct | 1987 |
[Calcium antagonists in ischemic heart disease].
Topics: Calcium Channel Blockers; Coronary Disease; Diltiazem; Hemodynamics; Humans; Nifedipine; Verapamil | 1987 |
A possible relationship between migraine and coronary artery spasm.
Topics: Coronary Disease; Coronary Vasospasm; Electrocardiography; Female; Humans; Middle Aged; Migraine Dis | 1986 |
Haemodynamic effects of verapamil administration after large doses of fentanyl in man.
Topics: Adult; Aged; Anesthesia, General; Blood Pressure; Coronary Artery Bypass; Coronary Disease; Diazepam | 1986 |
Protection of ischemic hearts by Ca2+ antagonists.
Topics: Animals; Bepridil; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Energy Metabolism | 1986 |
Effects of short-term infusion of nifedipine or verapamil on systemic hemodynamics and left ventricular myocardial contractility in patients prior to coronary artery bypass surgery.
Topics: Adult; Coronary Artery Bypass; Coronary Disease; Hemodynamics; Humans; Infusions, Intravenous; Male; | 1987 |
[Evaluation of the efficacy of verapamil and nifedipine as long-term crossover therapy with individually selected doses in ischemic heart disease. Work Group for the Cooperative Study of Antianginal Preparations (SCAP)].
Topics: Adult; Angina Pectoris; Coronary Disease; Exercise Test; Humans; Male; Middle Aged; Nifedipine; Time | 1987 |
Brief periods of myocardial ischemia followed by reperfusion: a model in the dog of sudden cardiac death in humans.
Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Death, Sudden; Disease Mode | 1987 |
Prevention of myocardial electrical activity during ischemic arrest with verapamil cardioplegia.
Topics: Animals; Cardiopulmonary Bypass; Coronary Disease; Dogs; Electrodes; Heart; Heart Arrest, Induced; H | 1987 |
[Protective action of the calcium antagonist foridon in acute myocardial ischemia].
Topics: Acute Disease; Animals; Aspartate Aminotransferases; Calcium Channel Blockers; Coronary Disease; Cre | 1987 |
[Relationship between adenine nucleotide breakdown and catecholamine losses in myocardial ischemia and the recovery of contractile function during reperfusion].
Topics: Adenine Nucleotides; Animals; Catecholamines; Cesium; Chlorides; Coronary Disease; Desipramine; Guin | 1987 |
Protection by verapamil of mitochondrial glutathione equilibrium and phospholipid changes during reperfusion of ischemic canine myocardium.
Topics: Acetyl-CoA C-Acyltransferase; Animals; Calcium; Coronary Disease; Dogs; Fatty Acids; Female; Glutath | 1987 |
[Prevention of myocardial damage during reperfusion of the coronary artery in dogs using dibunol combined with verapamil].
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Coronary Circulation; Coronary Disease; Coronary Th | 1987 |
Effect of changes in ventricular relaxation on early diastolic coronary blood flow in canine hearts.
Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Diastole; Dogs; Heart Ventricles; | 1987 |
Regional effects of verapamil on recovery of excitability and conduction time in experimental ischemia.
Topics: Action Potentials; Animals; Cats; Coronary Circulation; Coronary Disease; Electrophysiology; Endocar | 1987 |
[Comparative study of the acute hemodynamic effects of verapamil and nifedipine in patients with ischemic heart disease].
Topics: Coronary Disease; Female; Hemodynamics; Humans; Male; Nifedipine; Verapamil | 1987 |
[Effect of dibunol and isoptin on the creatine kinase and myoglobin content of the blood serum in dogs undergoing postischemic coronary reperfusion].
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Calcium Channel Blockers; Coronary Disease; Creatin | 1987 |
[Effect of isoptin on intrahepatic and central hemodynamics in ischemic heart disease].
Topics: Adult; Angina Pectoris; Coronary Disease; Drug Evaluation; Glucose Tolerance Test; Hemodynamics; Hum | 1987 |
Late follow-up (41 to 102 months) of medically treated patients with coronary artery spasm and minor atherosclerotic coronary obstructions.
Topics: Coronary Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifedipine; Prognosis; Verap | 1986 |
An experimental approach to the choice of antiarrhythmic therapy.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Diltiazem | 1986 |
Actions of the verapamil analogues, anipamil and ronipamil, against ischaemia-induced arrhythmias in conscious rats.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Electro | 1986 |
Effect of verapamil on infarct size in dogs subjected to coronary artery occlusion with transient reperfusion.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Femal | 1986 |
Effects of verapamil on regional myocardial diastolic function in pacing-induced ischemia in dogs.
Topics: Animals; Caffeine; Cardiac Pacing, Artificial; Coronary Disease; Diastole; Dogs; Heart; Hemodynamics | 1986 |
[Effects of verapamil on recovery of postischemic cardiac function under 2 MAC enflurane and isoflurane anesthesia in the isolated rat heart].
Topics: Anesthesia, Inhalation; Animals; Coronary Circulation; Coronary Disease; Enflurane; Hemodynamics; In | 1986 |
Molecular and ultrastructural basis of left ventricular reperfusion dysfunction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium Chloride; Coronary Disease; Dinitrof | 1986 |
The mechanism of action of the optical enantiomers of verapamil against ischaemia-induced arrhythmias in the conscious rat.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Electric Stimulation; Male; Myocardial Contractio | 1986 |
Hyperkalemia, verapamil, and dantrolene.
Topics: Colectomy; Colonic Neoplasms; Coronary Disease; Dantrolene; Drug Interactions; Humans; Hyperkalemia; | 1987 |
Electrical changes produced by injury to the rat myocardium in vitro and the protective effects of certain antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Calcium; Coronary Disease; Electric Stimulation; Heart Conduction S | 1987 |
Animal models for protecting ischemic myocardium: results of the NHLBI Cooperative Study. Comparison of unconscious and conscious dog models.
Topics: Anesthesia; Animal Testing Alternatives; Animals; Arterial Occlusive Diseases; Coronary Circulation; | 1985 |
[Administration of verapamil and propranolol for 4 years in a patient with aortocoronary bypass].
Topics: Coronary Artery Bypass; Coronary Disease; Drug Therapy, Combination; Humans; Male; Middle Aged; Prop | 1985 |
Intraoperative use of verapamil for nitroglycerin--refractory myocardial ischemia.
Topics: Aged; Coronary Disease; Drug Resistance; Humans; Intraoperative Period; Male; Nitroglycerin; Verapam | 1985 |
Vasodilator synchronized retroperfusion: quantitative assessment of flow-function relation in acutely ischemic canine myocardium.
Topics: Acute Disease; Animals; Coronary Disease; Diastole; Dogs; Female; Hemodynamics; Male; Myocardial Con | 1985 |
[Characteristics of patients with ischemic heart disease under dispensary observation in a regional polyclinic and the evaluation of anti-angina therapy conducted under dispensary conditions].
Topics: Adult; Ambulatory Care; Amiodarone; Angina Pectoris; Coronary Disease; Drug Therapy, Combination; Fo | 1985 |
[Synergism of the anti-anginal action of beta-blockers and calcium antagonists in patients with ischemic heart disease].
Topics: Adult; Angina Pectoris; Blood Pressure; Coronary Disease; Drug Therapy, Combination; Heart Rate; Hum | 1985 |
Effects of verapamil on ischemia-induced changes in extracellular K+, pH, and local activation in the pig.
Topics: Animals; Blood Pressure; Coronary Disease; Extracellular Space; Heart Rate; Heart Ventricles; Hydrog | 1986 |
The efficacy of lidocaine and verapamil alone and in combination on spontaneously occurring automatic ventricular tachycardia in conscious dogs one day after right coronary artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Cardiac Pacing, Artificial; Coronary Disease; | 1986 |
Cellular electrophysiologic changes and "arrhythmias" during experimental ischemia and reperfusion in isolated cat ventricular myocardium.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Cats; Coronary Circulation; Coronary Dise | 1986 |
Comparison of the protective effects of verapamil, diltiazem, nifedipine, and buffer containing low calcium upon global myocardial ischemic injury.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzazepines; Blood Pressure; Buffers; Calci | 1986 |
Comparative effects of calcium-channel blocking agents on left ventricular function during acute ischemia in dogs with and without congestive heart failure.
Topics: Animals; Arterial Occlusive Diseases; Calcium Channel Blockers; Coronary Circulation; Coronary Disea | 1985 |
Creatine kinase and phosphorylase in cardiac lymph: coronary occlusion and reperfusion.
Topics: Animals; Constriction; Coronary Circulation; Coronary Disease; Coronary Vessels; Creatine Kinase; Do | 1985 |
Effects of calcium entry blockers on coronary constriction and myocardial ischemia due to leukotriene D4.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Femal | 1985 |
A model for cardiac ischemia. Cardiac cells transplanted into the renal capsular space of the rat and their electrophysiological properties.
Topics: Animals; Coronary Circulation; Coronary Disease; Electrocardiography; Female; Heart Ventricles; Male | 1985 |
Protection of canine cardiac mitochondrial function by verapamil-cardioplegia during ischemic arrest.
Topics: Animals; Coronary Disease; Dogs; Fatty Acids; Heart Arrest, Induced; Mitochondria, Heart; Oxygen Con | 1985 |
Effect of verapamil on pH of ischemic canine myocardium.
Topics: Animals; Blood Pressure; Cardiac Output; Coronary Disease; Dogs; Dose-Response Relationship, Drug; H | 1985 |
[Various aspects of the effects of beta adrenergic receptor blockaders, stimulants and calcium antagonists on the cardiovascular system].
Topics: Adult; Animals; Calcium Channel Blockers; Cardiovascular System; Cats; Coronary Disease; Coronary Ve | 1985 |
Improved coronary supply: prevailing mechanism of action of nitrates in chronic stable angina.
Topics: Adult; Aged; Angina Pectoris; Arterial Occlusive Diseases; Cardiac Volume; Chronic Disease; Coronary | 1985 |
Effects of verapamil on the extracellular K+ rise during myocardial ischaemia in dogs.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Extracellular Space; Female; Hemodynamics; Ma | 1985 |
[Regulating role of phospholipids in the positive effect of isoptin in myocardial ischemia].
Topics: Animals; Coronary Disease; Male; Myocardium; Phospholipids; Rats; Verapamil | 1985 |
Protection by verapamil of globally ischemic rat hearts: energy preservation, a partial explanation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Disease; Energy Metabolism; Heart; | 1985 |
Plasma levels and myocardial content of verapamil, norverapamil and two N-dealkyl-metabolites in man.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Coronary Disease; Female; Heart Valve Diseases; H | 1985 |
[Effects of calcium antagonists on conduction delay in myocardial ischemia and reperfusion].
Topics: Animals; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Diltiazem; Dogs; Heart Conduc | 1985 |
[Arrhythmias in the elderly patients: atrial fibrillation].
Topics: Aged; Aging; Atrial Fibrillation; Coronary Disease; Diltiazem; Humans; Hypertension; Mitral Valve In | 1985 |
Evidence of histamine-induced myocardial ischaemia: reversal by chlorpheniramine and potentiation by atherosclerosis.
Topics: Animals; Arteriosclerosis; Chlorpheniramine; Cimetidine; Coronary Circulation; Coronary Disease; Cor | 1985 |
[Treatment of ischemic heart disease with verapamil].
Topics: Adult; Aged; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contracti | 1985 |
[The effect of verapamil in coronary insufficiency and cardiac arrhythmia].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiac Complexes, Premat | 1970 |
[Verapamil in the treatment of patients with coronary insufficiency].
Topics: Adult; Aged; Angina Pectoris; Anti-Arrhythmia Agents; Apnea; Arteriosclerosis; Cardiac Complexes, Pr | 1970 |
[Verapamil for regulation of cardiac rhythm disorders. Experience with our own patients].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Cardiac Complexes, Pre | 1970 |
[Effect of some coronary active drugs on angina threshold, ECG reaction and myocardial metabolism during frequency load in coronary disease patients].
Topics: Adenosine; Adrenergic beta-Agonists; Benzyl Compounds; Coronary Disease; Electrocardiography; Humans | 1973 |
[The treatment of heart arrhythmia with the heart sympatholytic iproveratril].
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Com | 1967 |
[Treatment of coronary disease patients with Verapamil (Isoptin)].
Topics: Adenosine Triphosphatases; Adult; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Calcium; Co | 1972 |
Mortality in ischaemic heart disease: a biased view point.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Artery Bypass; Coronary Care Units; Coronary | 1974 |
[The effect of isoptin on changes in the concentration of potassium in the bodies of patients with hypertension and coronary insufficiency].
Topics: Adult; Coronary Disease; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Verapamil | 1972 |
[Gradulon and gradulon s. T. in the treatment of heart diseases of various causes in the daily practice].
Topics: Arrhythmias, Cardiac; Benzoates; Coronary Disease; Digoxin; Drug Combinations; Heart Diseases; Heart | 1972 |
[Clinical pathophysiological studies on the effects of various coronary vasodilators on myocardial carbohydrate metabolism. 2. Effects of various coronary vasodilators on myocardial carbohydrate metabolism in various diseases].
Topics: Adolescent; Adult; Aged; Benzoates; Benzofurans; Blood Glucose; Carbohydrate Metabolism; Coronary Di | 1972 |
Clinical trial of a new coronary dilator (verapamil hydrochloride) in ischemic heart disease.
Topics: Adult; Aged; Coronary Disease; Female; Humans; Male; Middle Aged; Verapamil | 1973 |
Digitalis and atrial tachycardia with block.
Topics: Adult; Aged; Coronary Disease; Digitoxin; Electric Countershock; Electrocardiography; Female; Heart | 1974 |
Concealed bypasses of the atrioventricular mode in patients with paroxysmal supraventricular tachycardia revealed by intracardiac electrical stimulation and verapamil.
Topics: Adult; Aged; Atrial Fibrillation; Coronary Disease; Electrocardiography; Female; Heart Conduction Sy | 1974 |
Effect of nitroglycerin, intensain, isoptin and papaverine on coronary blood flow in man. Measured by the coincidence counting technic and rubidium.
Topics: Adult; Aged; Angina Pectoris; Blood Circulation; Coronary Disease; Female; Heart Function Tests; Hum | 1966 |
[Internal medical diagnosis and therapy of coronary insufficiency].
Topics: Coronary Disease; Dipyridamole; Electrocardiography; Humans; Myocardium; Nitroglycerin; Oxygen Consu | 1969 |
[Comparative animal experimental studies of the effectivity of various blood vessel and myocardium ACTIVE SUBSTANCES IN AN ACUTE TRIAL].
Topics: Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Blood Pressure; Cardiac Output; Cardiac Volume | 1969 |
[Verapamil in ischemic pain and arrhythmia].
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Coronary Disease; Depression, Chemical; Female; | 1972 |
[Our experiences with the preparation Isoptin associated with exercise therapy].
Topics: Coronary Disease; Drug Tolerance; Evaluation Studies as Topic; Exercise Therapy; Humans; Verapamil | 1971 |
[Clinical physiopathological studies on myocardial oxygen metabolism. 3. Myocardial oxygen metabolism during administration of coronary dilators].
Topics: Adolescent; Adult; Aged; Benzoates; Benzofurans; Coronary Disease; Coumarins; Dipyridamole; Female; | 1971 |
[Clinical pathophysiological studies on coronary circulation. 3. The effects of so-called coronary vasodilator agents on coronary circulation in various diseases].
Topics: Adolescent; Adult; Aged; Benzoates; Benzofurans; Blood Flow Velocity; Blood Pressure; Coronary Disea | 1971 |
[Drugs used in the treatment of coronary insufficiency (a guide line) to the young physician].
Topics: Coronary Disease; Coumarins; Humans; Monoamine Oxidase Inhibitors; Nitrates; Nitrites; Phenothiazine | 1971 |
[Isoptin in the treatment of ischemic heart disease].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Disease; Female; Humans; Male; Middle Aged; Nitriles; | 1969 |
Coronary vasodilators--iproveratril, a clinical trial.
Topics: Anti-Arrhythmia Agents; Coronary Disease; Electrocardiography; Humans; Nitriles; Vasodilator Agents; | 1970 |
[Clinical assessment of certain preparations used in coronary insufficiency].
Topics: Anti-Arrhythmia Agents; Benzoates; Coronary Disease; Humans; Nitriles; Papaverine; Prenylamine; Quin | 1970 |
[Clinical trials of the effect of verapamil in subjects with angina pectoris].
Topics: Adult; Aged; Angina Pectoris; Anti-Arrhythmia Agents; Arteriosclerosis; Coronary Disease; Female; He | 1970 |
[Intensain treatment of acute coronary insufficiency].
Topics: Adult; Coronary Disease; Coumarins; Glycolates; Humans; Male; Middle Aged; Propranolol; Vasodilator | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
[Behavior of the microcirculation in the experimental treatment of coronary insufficiency with verapamil and the clinical use of verapamil in revascularization of the heart].
Topics: Animals; Anti-Arrhythmia Agents; Blood Circulation; Capillaries; Collateral Circulation; Coronary Di | 1970 |
[Objective evaluation of the therapeutic activity of iproveratril].
Topics: Adult; Anti-Arrhythmia Agents; Coronary Disease; Electrocardiography; Exercise Test; Heart; Humans; | 1971 |
[Sympatholytic ("antisympathotonic") substances].
Topics: Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Coronary Disease; Coronary Vessels; Heart; Hum | 1968 |
[On the effectiveness of orally administered coronary dilator agents].
Topics: Benzoates; Benzopyrans; Butyrates; Coronary Disease; Coumarins; Dipyridamole; Glycolates; Humans; Pi | 1968 |
[On the clinical trial of a heart and coronary drug].
Topics: Adult; Aged; Cardiac Glycosides; Coronary Disease; Heart Diseases; Heart Failure; Humans; Middle Age | 1968 |
[Our experiences with the beta-adrenolytic preparation Isoptin Knoll A.G].
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Coronary Disease; Electrocardiography; Female; Humans; Lana | 1969 |
[Isoptin studies on normal subjects and patients with coronary disease].
Topics: Adult; Angina Pectoris; Anti-Arrhythmia Agents; Blood Pressure; Coronary Disease; Electrocardiograph | 1963 |
[Treatment of coronary diseases: study of a new drug, iproveratril].
Topics: Anti-Arrhythmia Agents; Coronary Disease; Humans; Vasodilator Agents; Verapamil | 1966 |
[New data on the drug therapy of angina pectoris].
Topics: Angina Pectoris; Coronary Disease; Dipyridamole; Humans; Monoamine Oxidase Inhibitors; Prenylamine; | 1966 |