Page last updated: 2024-10-24

verapamil and Constriction, Pathologic

verapamil has been researched along with Constriction, Pathologic in 17 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.

Research Excerpts

ExcerptRelevanceReference
" Forearm blood flow was determined by venous occlusion plethysmography, and dose-response curves were generated for each agent."1.29Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus. ( Creager, MA; Cusco, JA; Johnstone, MT; Roddy, MA; Williams, SB, 1996)
"Lidocaine was the most successful drug treatment alone."1.28Hydrostatic distention and pharmacological treatment of epinephrine-induced microarterial spasm. ( Angel, MF; Mahoney, JE; Mitchell, GM; Morrison, WA; O'Brien, BM; Pederson, WC; Singer, DI, 1989)
"Submaximal histamine dose-response curves were obtained on 34 dogs divided into six groups."1.27Interaction of verapamil hydrochloride and atropine sulphate on histamine-induced bronchoconstriction. ( Brandt, HD; Bunn, AE; Krivoy, N, 1985)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199011 (64.71)18.7374
1990's3 (17.65)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Cai, B1
Yuan, B1
Cui, J1
Li, J1
Zhang, Y1
Qing, Z1
Yuan, W1
Wang, J1
Song, W1
Luo, J1
Wu, X1
Lu, Q1
Li, Y1
Zeng, M1
Lowe, HC1
Macina, A1
Torosoff, M1
Millar, RD1
Campolo, L1
Casolo, F1
Pirelli, S1
Inglese, E1
Angus, JA1
Brazenor, RM1
Le Duc, MA1
McIntyre, E1
Fitzgibbon, B1
Otto, H1
Minson, R1
Alpers, J1
Ruffin, R1
Osakada, G1
Kumada, T1
Gallagher, KP1
Kemper, WS1
Ross, J1
Williams, SB1
Cusco, JA1
Roddy, MA1
Johnstone, MT1
Creager, MA1
Hoberg, E1
Uchida, Y1
Yoshimoto, N1
Murao, S1
Chou, SY1
Reiser, I1
Porush, JG1
Ishchenko, MM1
Lobas, VA1
Pederson, WC1
Singer, DI1
Angel, MF1
Mahoney, JE1
Mitchell, GM1
Morrison, WA1
O'Brien, BM1
Juliard, JM1
Charlier, P1
Nitenberg, A1
Mérillon, JP1
Masquet, C1
Gourgon, R1
Betocchi, S1
Bonow, RO1
Bacharach, SL1
Rosing, DR1
Maron, BJ1
Green, MV1
Krivoy, N1
Brandt, HD1
Bunn, AE1
Rosenblum, WI1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Watermelon Juice Supplementation on Postprandial Vascular Endothelial Function and Blood Flow During Hyperglycemia: A Pilot Study[NCT04092439]18 participants (Actual)Interventional2019-09-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for verapamil and Constriction, Pathologic

ArticleYear
The effects of calcium antagonists after PTCA.
    European heart journal, 1995, Volume: 16 Suppl H

    Topics: Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Clinical Trials as Topic; Constriction, Pa

1995

Trials

2 trials available for verapamil and Constriction, Pathologic

ArticleYear
Inhaled verapamil in histamine-induced bronchoconstriction.
    The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:4

    Topics: Adult; Bronchial Diseases; Bronchial Provocation Tests; Bronchial Spasm; Constriction, Pathologic; D

1983
[Effect of calcium antagonists on cerebral and systemic hemodynamics in patients with ischemic disorders of cerebrovascular circulation].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1989, Volume: 89, Issue:9

    Topics: Adult; Aged; Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Internal; Cerebrovascular Circ

1989

Other Studies

14 other studies available for verapamil and Constriction, Pathologic

ArticleYear
Inhibitory Effect of Verapamil on the Growth of Human Airway Granulation Fibroblasts.
    Combinatorial chemistry & high throughput screening, 2023, Volume: 26, Issue:4

    Topics: Calcium Channel Blockers; Cells, Cultured; Constriction, Pathologic; Fibroblasts; Humans; Interleuki

2023
Verapamil inhibited the development of ureteral stricture by blocking CaMK II-mediated STAT3 and Smad3/JunD pathways.
    International urology and nephrology, 2022, Volume: 54, Issue:11

    Topics: Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Collagen; Collagen Typ

2022
Recurrent spasm of radial artery graft mimicking fixed stenosis.
    The Journal of invasive cardiology, 2002, Volume: 14, Issue:10

    Topics: Arterial Occlusive Diseases; Blood Vessel Prosthesis Implantation; Cardiac Catheterization; Constric

2002
Percutaneous transluminal coronary angioplasty. Critical assessment of preliminary results.
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:9

    Topics: Angioplasty, Balloon; Constriction, Pathologic; Coronary Disease; Humans; Nitrates; Premedication; V

1984
Responses of dog large coronary arteries to constrictor and dilator substances: implications for the cause and treatment of variant angina pectoris.
    The American journal of cardiology, 1983, Jul-20, Volume: 52, Issue:2

    Topics: Angina Pectoris, Variant; Animals; Arteries; Constriction, Pathologic; Coronary Vasospasm; Coronary

1983
Reduction of exercise-induced ischemic regional myocardial dysfunction by verapamil in conscious dogs.
    American heart journal, 1981, Volume: 101, Issue:6

    Topics: Animals; Blood Pressure; Cardiovascular System; Constriction, Pathologic; Coronary Disease; Dogs; Ex

1981
Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus.
    Journal of the American College of Cardiology, 1996, Mar-01, Volume: 27, Issue:3

    Topics: Adult; Analysis of Variance; Blood Flow Velocity; Case-Control Studies; Constriction, Pathologic; Di

1996
Effect of 2-nicotinamidethyl nitrate (SG 75) on coronary circulation.
    Japanese heart journal, 1978, Volume: 19, Issue:1

    Topics: Animals; Constriction, Pathologic; Coronary Circulation; Coronary Vessels; Diltiazem; Dogs; Heart Ra

1978
Reversal of Na+ retention in chronic caval dogs by verapamil: contribution of medullary circulation.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 2

    Topics: Animals; Cardiac Output, Low; Chronic Disease; Constriction, Pathologic; Dinoprostone; Dogs; Female;

1992
Hydrostatic distention and pharmacological treatment of epinephrine-induced microarterial spasm.
    Annals of plastic surgery, 1989, Volume: 23, Issue:1

    Topics: Animals; Chlorpromazine; Constriction, Pathologic; Epinephrine; Femoral Artery; Isotonic Solutions;

1989
[Non-obstructive hypertrophic cardiomyopathy and systolic compression of 3 coronary arteries. Long-term improvement with verapamil].
    Annales de medecine interne, 1987, Volume: 138, Issue:7

    Topics: Adult; Cardiomyopathy, Hypertrophic; Constriction, Pathologic; Coronary Disease; Echocardiography; E

1987
Isovolumic relaxation period in hypertrophic cardiomyopathy: assessment by radionuclide angiography.
    Journal of the American College of Cardiology, 1986, Volume: 7, Issue:1

    Topics: Adult; Aged; Cardiomyopathy, Hypertrophic; Constriction, Pathologic; Echocardiography; Female; Heart

1986
Interaction of verapamil hydrochloride and atropine sulphate on histamine-induced bronchoconstriction.
    Respiration; international review of thoracic diseases, 1985, Volume: 47, Issue:3

    Topics: Airway Resistance; Animals; Atropine; Bronchial Diseases; Constriction, Pathologic; Dogs; Dose-Respo

1985
Inhibition of barium-induced constriction of cerebral surface arterioles by blockers of calcium channels.
    Blood vessels, 1985, Volume: 22, Issue:3

    Topics: Animals; Barium; Barium Compounds; Calcium Channel Blockers; Chlorides; Constriction, Pathologic; Ma

1985