verapamil has been researched along with Complications of Diabetes Mellitus in 14 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Aim of the study was treatment of hypertension in patients with DM of both types by the ACE inhibitor trandolapril in dose of 2-4 mg, possibly in combination with the calcium channel blocker verapamil--240 mg." | 9.10 | [Treatment of hypertension in diabetics with trandolapril, an angiotensin converting enzyme inhibitor--a multicenter study]. ( Cech, F; Rosolová, H; Sefrna, F, 2002) |
| " Aim of the study was treatment of hypertension in patients with DM of both types by the ACE inhibitor trandolapril in dose of 2-4 mg, possibly in combination with the calcium channel blocker verapamil--240 mg." | 5.10 | [Treatment of hypertension in diabetics with trandolapril, an angiotensin converting enzyme inhibitor--a multicenter study]. ( Cech, F; Rosolová, H; Sefrna, F, 2002) |
| " The aim of this study was to compare the effect of trandolapril (T) and its fixed-dose combination with verapamil (FDTV) on SAM levels in hypertensive type-2 diabetic patients." | 2.73 | The effect of trandolapril and its fixed-dose combination with verapamil on circulating adhesion molecules levels in hypertensive patients with type 2 diabetes. ( Escalante-Acosta, BA; Rodriguez-Lopez, L; Rubio-Guerra, AF; Vargas-Ayala, G; Vargas-Robles, H, 2008) |
| "Lung injury has recently been recognized as a consequent complication of diabetes mellitus." | 1.48 | STAT3 and Nrf2 pathways modulate the protective effect of verapamil on lung injury of diabetic rats. ( Hafez, HM; Mohamed, HH; Mohamed, MZ; Zenhom, NM, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mohamed, MZ | 1 |
| Hafez, HM | 1 |
| Mohamed, HH | 1 |
| Zenhom, NM | 1 |
| Rubio-Guerra, AF | 1 |
| Vargas-Robles, H | 1 |
| Vargas-Ayala, G | 1 |
| Rodriguez-Lopez, L | 1 |
| Escalante-Acosta, BA | 1 |
| Rosolová, H | 1 |
| Cech, F | 1 |
| Sefrna, F | 1 |
| Oganov, RG | 1 |
| Lepakhin, VK | 1 |
| Fitilev, SB | 1 |
| Levin, AM | 1 |
| Titarova, YY | 1 |
| Sytchev, EN | 1 |
| Bakris, GL | 1 |
| Gaxiola, E | 1 |
| Messerli, FH | 1 |
| Mancia, G | 1 |
| Erdine, S | 1 |
| Cooper-DeHoff, R | 1 |
| Pepine, CJ | 1 |
| Gurevich, MA | 1 |
| Blackshear, JL | 1 |
| Kopecky, SL | 1 |
| Litin, SC | 1 |
| Safford, RE | 1 |
| Hammill, SC | 1 |
| Streier, K | 1 |
| Pinar, E | 1 |
| García-Alberola, A | 1 |
| Llamas, C | 1 |
| Vicente, T | 1 |
| López-Candel, J | 1 |
| Rojo, JL | 1 |
| Fernández, R | 1 |
| Valdés, M | 1 |
| Mallion, JM | 1 |
| Maitre, A | 1 |
| de Gaudemaris, R | 1 |
| Siché, JP | 1 |
| Tremel, F | 1 |
| Ferrier, C | 1 |
| Ferrari, P | 1 |
| Weidmann, P | 1 |
| Keller, U | 1 |
| Beretta-Piccoli, C | 1 |
| Riesen, WF | 1 |
| Cruickshank, JK | 1 |
| Anderson, NM | 1 |
| Wadsworth, J | 1 |
| Young, SM | 1 |
| Jepson, E | 1 |
| Souviron Rodríguez, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| INternational VErapamil SR Trandolapril STudy[NCT00133692] | Phase 4 | 22,000 participants | Interventional | 1997-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for verapamil and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Management of atrial fibrillation in adults: prevention of thromboembolism and symptomatic treatment.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Aspirin; Atrial Fibri | 1996 |
[Verapamil: a 1st choice antihypertensive agent].
Topics: Coronary Disease; Diabetes Complications; Humans; Hypertension; Sodium, Dietary; Verapamil | 1989 |
5 trials available for verapamil and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
The effect of trandolapril and its fixed-dose combination with verapamil on circulating adhesion molecules levels in hypertensive patients with type 2 diabetes.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; C | 2008 |
[Treatment of hypertension in diabetics with trandolapril, an angiotensin converting enzyme inhibitor--a multicenter study].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabete | 2002 |
Use of ambulatory blood pressure monitoring in the management of antihypertensive therapy.
Topics: Blood Pressure Monitors; Delayed-Action Preparations; Diabetes Complications; Double-Blind Method; H | 1992 |
Swiss hypertension treatment programme with verapamil and/or enalapril in diabetic patients.
Topics: Adolescent; Adult; Aged; Blood Glucose; Blood Pressure; Creatinine; Diabetes Complications; Drug The | 1992 |
Treating hypertensive diabetics: a comparison of verapamil and metoprolol in black and white patients.
Topics: Albuminuria; Black People; Blood Glucose; Blood Pressure; Cholesterol; Diabetes Complications; Diabe | 1987 |
7 other studies available for verapamil and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
STAT3 and Nrf2 pathways modulate the protective effect of verapamil on lung injury of diabetic rats.
Topics: Animals; Antioxidants; Cytoprotection; Diabetes Complications; Diabetes Mellitus, Experimental; Lung | 2018 |
[Diagnosis and therapy of stable angina in Russian Federation (International Study ATP - angina treatment pattern)].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Angina Pectoris; Angiotens | 2003 |
Clinical outcomes in the diabetes cohort of the INternational VErapamil SR-Trandolapril study.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents | 2004 |
Adult hypertension: reducing cardiovascular morbidity and mortality.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking | 2005 |
[Characteristic features of the pathogenesis and treatment of coronary heart diseases, heart failure and arterial hypertension in patients with diabetes mellitus].
Topics: Adrenergic beta-Antagonists; Adult; Aspirin; Blood Glucose; Calcium Channel Blockers; Clinical Trial | 2005 |
[Obesity in the service of Justice. New drug-combination leads to protection of the kidney].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus; Diabet | 1997 |
Effects of verapamil on indexes of heart rate variability after acute myocardial infarction.
Topics: Adult; Aged; Aged, 80 and over; Autonomic Nervous System; Diabetes Complications; Diabetes Mellitus; | 1998 |