verapamil has been researched along with Cirrhoses, Experimental Liver in 7 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Verapamil treated fibrotic rat's liver revealed significant regression in liver fibrosis scores with positive α-SMA immunostaining." | 1.37 | Improved antifibrotic effect of a combination of verapamil and silymarin in rat-induced liver fibrosis. ( Gouda, NA; Khodeir, MM; Mahmoud, ME; Shafik, AN, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, D | 1 |
| Chen, M | 1 |
| Guo, Y | 1 |
| Liang, G | 1 |
| Zhang, B | 1 |
| Tan, J | 1 |
| Magdalou, J | 1 |
| Wang, H | 1 |
| Shafik, AN | 1 |
| Khodeir, MM | 1 |
| Gouda, NA | 1 |
| Mahmoud, ME | 1 |
| Hanisch, E | 1 |
| Strasse, R | 1 |
| Wenzel, M | 1 |
| Lorey, T | 1 |
| Altmann, O | 1 |
| Li, D | 1 |
| Reichen, J | 2 |
| Le, M | 1 |
| Hirlinger, A | 1 |
| Ha, HR | 1 |
| Sägesser, S | 1 |
7 other studies available for verapamil and Cirrhoses, Experimental Liver
| Article | Year |
|---|---|
Synergistic antifibrotic effect of verapamil and interferon-gamma in rats: partially based on enhanced verapamil oral bioavailability.
Topics: Animals; Antiviral Agents; Area Under Curve; Biological Availability; Calcium Channel Blockers; Cyto | 2010 |
Improved antifibrotic effect of a combination of verapamil and silymarin in rat-induced liver fibrosis.
Topics: Administration, Oral; Alanine Transaminase; Animals; Dose-Response Relationship, Drug; Drug Therapy, | 2011 |
[In vitro contractility behavior of portal veins in normal rats and in rats with liver cirrhosis--effect of calcium antagonists and octreotide].
Topics: Animals; Blood Pressure; Culture Techniques; Dose-Response Relationship, Drug; Hypertension, Portal; | 1993 |
[Pharmacological lowering of portal pressure in normal rats and in experimental liver cirrhosis].
Topics: Acute Disease; Animals; Blood Pressure; Canrenoic Acid; Heart Rate; Hypertension, Portal; Liver Cirr | 1991 |
[Use of calcium-channel blockers in cirrhotic patients with portal hypertension].
Topics: Adolescent; Adult; Aged; Alkaloids; Animals; Benzylisoquinolines; Calcium Channel Blockers; Cinnariz | 1990 |
Verapamil favorably influences hepatic microvascular exchange and function in rats with cirrhosis of the liver.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Capillary Permeability; Extracellular Space; Liver; Li | 1986 |
Chronic verapamil administration lowers portal pressure and improves hepatic function in rats with liver cirrhosis.
Topics: Animals; Blood Pressure; Hypertension, Portal; Liver; Liver Cirrhosis, Experimental; Liver Function | 1986 |