verapamil has been researched along with Cicatrix in 12 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the anti-cicatricial and anti-restenosis effect of verapamil on anterior urethral stricture." | 9.27 | [Anti-cicatricial and anti-restenosis effect of verapamil on anterior urethral stricture: A randomized controlled clinical trial]. ( Liao, J; Tang, Z; Tian, T; Xue, R, 2018) |
| "A double-blind randomized controlled trial with a paired split-scar design compared verapamil, an L-type Ca2+ channel antagonist, and triamcinolone for prevention of keloid recurrence after excision." | 9.22 | Verapamil is Less Effective than Triamcinolone for Prevention of Keloid Scar Recurrence After Excision in a Randomized Controlled Trial. ( Alghamdi, M; Danielsen, PL; Fear, MW; Gankande, TU; Hool, LC; Manzur, M; Rea, SM; Stevenson, AW; Viola, HM; Wallace, HJ; Wood, FM, 2016) |
| "To evaluate the anti-cicatricial and anti-restenosis effect of verapamil on anterior urethral stricture." | 5.27 | [Anti-cicatricial and anti-restenosis effect of verapamil on anterior urethral stricture: A randomized controlled clinical trial]. ( Liao, J; Tang, Z; Tian, T; Xue, R, 2018) |
| "A double-blind randomized controlled trial with a paired split-scar design compared verapamil, an L-type Ca2+ channel antagonist, and triamcinolone for prevention of keloid recurrence after excision." | 5.22 | Verapamil is Less Effective than Triamcinolone for Prevention of Keloid Scar Recurrence After Excision in a Randomized Controlled Trial. ( Alghamdi, M; Danielsen, PL; Fear, MW; Gankande, TU; Hool, LC; Manzur, M; Rea, SM; Stevenson, AW; Viola, HM; Wallace, HJ; Wood, FM, 2016) |
| "The aim of this research was to investigate the impact of calcium channel blockers (verapamil) on the formation of scars in the sciatic nerve anastomosis after peripheral nerve injury." | 3.83 | Inhibition of Peripheral Nerve Scarring by Calcium Antagonists, Also Known as Calcium Channel Blockers. ( Jiang, YT; Jiao, JB; Li, CY; Ling, L; Liu, XF; Xue, JW; Yang, G; Yin, WT, 2016) |
| "To investigate the effect of verapamil on the prevention of epidural fibrosis in laminectomy rats." | 3.80 | Calcium channel blockers in reduction of epidural fibrosis and dural adhesions in laminectomy rats. ( Liu, W; Wang, Y; Wang, Z; Xie, P; Zhang, S, 2014) |
| "For atrophic scars, different types of lasers represent modern treatment modalities with satisfactory results." | 2.42 | Novel opportunities in the treatment and prevention of scarring. ( Berman, B; Ramirez, CC; Villa, AM, 2004) |
| "Treatment of verapamil inhibits TGF-β1 induced collagen production via inhibiting CaMK II." | 1.62 | Verapamil inhibits ureteral scar formation by regulating CaMK II-mediated Smad pathway. ( Gao, ZY; Guo, X; Li, YW; Lu, Q; Wang, JS; Xiao, W; Yang, K; Yuan, WX; Zeng, MQ, 2021) |
| "The formation of hypertrophic scaring (HSc) is an abnormal wound-healing response." | 1.46 | A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study. ( Chuang, SS; Hsiao, YC; Yang, JY; Yang, SY, 2017) |
| "Autohemoperitoneum was simulated by intraperitoneal administration of autoblood (group 1)." | 1.36 | [Effect of verapamil on production of anti-inflammatory cytokines by peritoneal mononuclears]. ( Skal'skiĭ, SV, 2010) |
| "Scarring was documented in one patient." | 1.29 | Intracavernous self-injection of papaverine and verapamil: a clinical experience. ( Bolayir, K; Gökşin, N, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zeng, MQ | 1 |
| Xiao, W | 1 |
| Yang, K | 1 |
| Gao, ZY | 1 |
| Wang, JS | 1 |
| Lu, Q | 1 |
| Guo, X | 1 |
| Li, YW | 1 |
| Yuan, WX | 1 |
| Xue, R | 2 |
| Liao, J | 1 |
| Tian, T | 1 |
| Tang, Z | 2 |
| Zarbin, MA | 1 |
| Wang, Z | 1 |
| Wang, Y | 1 |
| Xie, P | 1 |
| Liu, W | 1 |
| Zhang, S | 1 |
| Xue, JW | 1 |
| Jiao, JB | 1 |
| Liu, XF | 1 |
| Jiang, YT | 1 |
| Yang, G | 1 |
| Li, CY | 1 |
| Yin, WT | 1 |
| Ling, L | 1 |
| Danielsen, PL | 1 |
| Rea, SM | 1 |
| Wood, FM | 1 |
| Fear, MW | 1 |
| Viola, HM | 1 |
| Hool, LC | 1 |
| Gankande, TU | 1 |
| Alghamdi, M | 1 |
| Stevenson, AW | 1 |
| Manzur, M | 1 |
| Wallace, HJ | 1 |
| Yang, SY | 1 |
| Yang, JY | 1 |
| Hsiao, YC | 1 |
| Chuang, SS | 1 |
| Zeng, M | 1 |
| Chen, J | 1 |
| Huang, L | 1 |
| Xiang, X | 1 |
| Zeng, F | 1 |
| Wang, G | 1 |
| Brock, G | 1 |
| Skal'skiĭ, SV | 1 |
| Berman, B | 1 |
| Villa, AM | 1 |
| Ramirez, CC | 1 |
| Bolayir, K | 1 |
| Gökşin, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intra-lesional ACE Inhibitor for Treatment of Hypertrophic Scars[NCT05259137] | Phase 2/Phase 3 | 30 participants (Anticipated) | Interventional | 2023-08-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for verapamil and Cicatrix
| Article | Year |
|---|---|
Novel opportunities in the treatment and prevention of scarring.
Topics: Bleomycin; Botulinum Toxins, Type A; Celecoxib; Cicatrix; Fluorouracil; Humans; Immunosuppressive Ag | 2004 |
2 trials available for verapamil and Cicatrix
| Article | Year |
|---|---|
[Anti-cicatricial and anti-restenosis effect of verapamil on anterior urethral stricture: A randomized controlled clinical trial].
Topics: Anastomosis, Surgical; Cicatrix; Dilatation; Humans; Male; Penis; Postoperative Complications; Secon | 2018 |
Verapamil is Less Effective than Triamcinolone for Prevention of Keloid Scar Recurrence After Excision in a Randomized Controlled Trial.
Topics: Adolescent; Adult; Cicatrix; Double-Blind Method; Female; Glucocorticoids; Humans; Injections, Intra | 2016 |
9 other studies available for verapamil and Cicatrix
| Article | Year |
|---|---|
Verapamil inhibits ureteral scar formation by regulating CaMK II-mediated Smad pathway.
Topics: Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Cicatrix; Collagen Type I; Coll | 2021 |
Combination therapy to reduce conjunctival scarring after glaucoma surgery.
Topics: Alkylating Agents; Apoptosis; Calcium Channel Blockers; Cicatrix; Conjunctival Diseases; Cyclosporin | 2013 |
Calcium channel blockers in reduction of epidural fibrosis and dural adhesions in laminectomy rats.
Topics: Animals; Calcium Channel Blockers; Cicatrix; Dura Mater; Epidural Space; Fibrosis; Hydroxyproline; I | 2014 |
Inhibition of Peripheral Nerve Scarring by Calcium Antagonists, Also Known as Calcium Channel Blockers.
Topics: Anastomosis, Surgical; Animals; Calcium Channel Blockers; Cicatrix; Collagen Type I; Male; Periphera | 2016 |
A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study.
Topics: Adolescent; Adult; Animals; Burns; Calcium Channel Blockers; Child; Child, Preschool; Cicatrix; Cica | 2017 |
[Effect of calcium channel blockers on primary cultured human urethra scar fibroblasts].
Topics: Calcium Channel Blockers; Cell Proliferation; Cells, Cultured; Cicatrix; Fibroblasts; Humans; Matrix | 2016 |
Clinical case: 45-year-old male with penile pain (CME).
Topics: Anthropometry; Cicatrix; Erectile Dysfunction; Humans; Male; Middle Aged; Penile Induration; Phospho | 2009 |
[Effect of verapamil on production of anti-inflammatory cytokines by peritoneal mononuclears].
Topics: Animals; Calcium Channel Blockers; Cicatrix; Cytokines; Hemoperitoneum; Macrophages, Peritoneal; Mal | 2010 |
Intracavernous self-injection of papaverine and verapamil: a clinical experience.
Topics: Adult; Aged; Cicatrix; Drug Combinations; Erectile Dysfunction; Hematoma; Humans; Injections; Male; | 1994 |