verapamil has been researched along with Cicatrix, Hypertrophic in 31 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Cicatrix, Hypertrophic: An elevated scar, resembling a KELOID, but which does not spread into surrounding tissues. It is formed by enlargement and overgrowth of cicatricial tissue and regresses spontaneously.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this clinical trial, we investigated the efficacy of two treatment methods for keloids resulting from surgical incisions: intralesional triamcinolone injections alone versus in combination with verapamil." | 9.69 | Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial. ( Esmailzadeh, M; Hadadi, R; Haghani-Dogahe, Z; Mobayen, M, 2023) |
| "Concerning the treatment of keloids and hypertrophic scars, TAC was more effective than verapamil for improving vascularity; TAC was superior to verapamil in improving height within 9 weeks of treatment; TAC produced superior result for improving pliability within 18 weeks of treatment, whereas verapamil produced superior result between 18 and 24 weeks of treatment." | 9.41 | Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis. ( Li, X; Zhang, W, 2023) |
| "Our results did not support verapamil's capability in treatment of keloid nor hypertrophic scars." | 9.27 | Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial. ( Abedini, R; Mahmoudi, HR; Nasimi, M; Sasani, P; Shadlou, Z; Teymourpour, A, 2018) |
| "The aim of this study was to conduct a meta-analysis of the effectiveness and safety of verapamil and TAC in the treatment of HSs and keloids." | 9.12 | Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials. ( Bi, H; Gu, L; Qin, Z; Wang, P; Wang, Q, 2021) |
| "Triamcinolone acetonide (TAC) is widely used for hypertrophic scars and keloids; however, TAC has variable efficacy and safety in different individuals." | 9.12 | The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021) |
| "It appears that TAC is more effective than verapamil for improving scar pliability and vascularity in keloids and hypertrophic scars after 3 weeks of treatment." | 9.05 | The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis. ( Fu, ZH; Guo, GH; Jiang, ZY; Liao, XC; Liu, MZ; Min, DH, 2020) |
| "To evaluate the effectiveness of combined ablative fractional CO2 laser and topically applied 5-fluorouracil (5-FU) or verapamil hydrochloride in the treatment of hypertrophic scars (HTSs) and keloids and to examine their possible effects on TGF-β1 expression." | 7.91 | The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study. ( Abd El Azez, TA; Abdel Rahman, SH; Hussein, MS; Sabry, HH; Sanad, RR, 2019) |
| "Keloids and hypertrophic scars are harmful to physical and psychological health." | 6.72 | Comparative efficacy and safety of verapamil and triamcinolone in keloid and hypertrophic scar treatment: a meta-analysis. ( An, P; Kuang, J; Li, W, 2021) |
| " Although triamcinolone acetonide (TAC) is one of the most common and effective treatments for keloids and hypertrophic scars, TAC is not effective in some patients, and some may even experience adverse outcomes." | 6.66 | Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Deng, Z; Liu, L; Liu, R; Yang, B; Zhao, X, 2020) |
| "In this clinical trial, we investigated the efficacy of two treatment methods for keloids resulting from surgical incisions: intralesional triamcinolone injections alone versus in combination with verapamil." | 5.69 | Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial. ( Esmailzadeh, M; Hadadi, R; Haghani-Dogahe, Z; Mobayen, M, 2023) |
| "Verapamil has shown a great potential in the management of keloid and hypertrophic scars." | 5.43 | Role of verapamil in preventing and treating hypertrophic scars and keloids. ( Cen, Y; Chen, J; Li, Z; Mao, Y; Wang, R; Zhang, Z, 2016) |
| "Concerning the treatment of keloids and hypertrophic scars, TAC was more effective than verapamil for improving vascularity; TAC was superior to verapamil in improving height within 9 weeks of treatment; TAC produced superior result for improving pliability within 18 weeks of treatment, whereas verapamil produced superior result between 18 and 24 weeks of treatment." | 5.41 | Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis. ( Li, X; Zhang, W, 2023) |
| "Our results did not support verapamil's capability in treatment of keloid nor hypertrophic scars." | 5.27 | Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial. ( Abedini, R; Mahmoudi, HR; Nasimi, M; Sasani, P; Shadlou, Z; Teymourpour, A, 2018) |
| "The aim of this study was to conduct a meta-analysis of the effectiveness and safety of verapamil and TAC in the treatment of HSs and keloids." | 5.12 | Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials. ( Bi, H; Gu, L; Qin, Z; Wang, P; Wang, Q, 2021) |
| "Triamcinolone acetonide (TAC) is widely used for hypertrophic scars and keloids; however, TAC has variable efficacy and safety in different individuals." | 5.12 | The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021) |
| "It appears that TAC is more effective than verapamil for improving scar pliability and vascularity in keloids and hypertrophic scars after 3 weeks of treatment." | 5.05 | The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis. ( Fu, ZH; Guo, GH; Jiang, ZY; Liao, XC; Liu, MZ; Min, DH, 2020) |
| "To evaluate the effectiveness of combined ablative fractional CO2 laser and topically applied 5-fluorouracil (5-FU) or verapamil hydrochloride in the treatment of hypertrophic scars (HTSs) and keloids and to examine their possible effects on TGF-β1 expression." | 3.91 | The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study. ( Abd El Azez, TA; Abdel Rahman, SH; Hussein, MS; Sabry, HH; Sanad, RR, 2019) |
| "Different approaches are used aiming to improve these scars, including intralesional corticosteroids, surgery and more recently, laser therapy." | 2.82 | Laser therapy for treating hypertrophic and keloid scars. ( da Silva, CA; da Silva, EM; Kuczynski, U; Leszczynski, R; Pinto, ACPN, 2022) |
| "Keloids and hypertrophic scars are harmful to physical and psychological health." | 2.72 | Comparative efficacy and safety of verapamil and triamcinolone in keloid and hypertrophic scar treatment: a meta-analysis. ( An, P; Kuang, J; Li, W, 2021) |
| " Although triamcinolone acetonide (TAC) is one of the most common and effective treatments for keloids and hypertrophic scars, TAC is not effective in some patients, and some may even experience adverse outcomes." | 2.66 | Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Deng, Z; Liu, L; Liu, R; Yang, B; Zhao, X, 2020) |
| "To provide a comprehensive evidence-based review of current evidence on mechanism of action, efficacy, and adverse events of calcium antagonists in treatment of hypertrophic scars and keloids." | 2.52 | Mechanism of Action, Efficacy, and Adverse Events of Calcium Antagonists in Hypertrophic Scars and Keloids: A Systematic Review. ( Piatkowski de Grzymala, A; van der Hulst, R; Verhiel, S, 2015) |
| "Keloids are special type of skin lesions arising from sites of previous trauma." | 2.43 | [Therapeutic problems connected with keloid treatment--new treatment possibilities]. ( Brudnik, U; Podolec-Rubiś, M; Wojas-Pelc, A, 2006) |
| "To treat persistent hypertrophic scars, local injection of drugs composed of steroids, calcium channel blockers (CCBs), and interferon might be a good method." | 1.46 | A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study. ( Chuang, SS; Hsiao, YC; Yang, JY; Yang, SY, 2017) |
| "Verapamil has shown a great potential in the management of keloid and hypertrophic scars." | 1.43 | Role of verapamil in preventing and treating hypertrophic scars and keloids. ( Cen, Y; Chen, J; Li, Z; Mao, Y; Wang, R; Zhang, Z, 2016) |
| " Combination therapy can reduce the dosage of each drug but achieve equal or better efficacy than monotherapy, reducing the side effects of a single drug." | 1.36 | The effect of combined steroid and calcium channel blocker injection on human hypertrophic scars in animal model: a new strategy for the treatment of hypertrophic scars. ( Huang, CY; Yang, JY, 2010) |
| "Verapamil can inhibit HSFB proliferation, collagen synthesis and gene expression by a dose-depended manner, especially treated with 100 mumol/L Verapamil." | 1.31 | [The biological effect of verapamil on hypertrophic scar fibroblast]. ( Guo, S; Lu, K; Wang, Z, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 4 (12.90) | 29.6817 |
| 2010's | 13 (41.94) | 24.3611 |
| 2020's | 13 (41.94) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, N | 1 |
| Xue, L | 1 |
| Younas, A | 1 |
| Liu, F | 1 |
| Sun, J | 1 |
| Dong, Z | 1 |
| Zhao, Y | 1 |
| Leszczynski, R | 1 |
| da Silva, CA | 1 |
| Pinto, ACPN | 1 |
| Kuczynski, U | 1 |
| da Silva, EM | 1 |
| Zhang, W | 1 |
| Li, X | 2 |
| Haghani-Dogahe, Z | 1 |
| Hadadi, R | 1 |
| Esmailzadeh, M | 1 |
| Mobayen, M | 1 |
| Teplyi, V | 1 |
| Grebchenko, K | 1 |
| Jiang, ZY | 1 |
| Liao, XC | 1 |
| Liu, MZ | 1 |
| Fu, ZH | 1 |
| Min, DH | 1 |
| Guo, GH | 1 |
| Liu, R | 1 |
| Yang, B | 1 |
| Deng, Z | 1 |
| Liu, L | 1 |
| Zhao, X | 1 |
| Ahuja, RB | 2 |
| Chatterjee, P | 2 |
| Wang, P | 2 |
| Gu, L | 2 |
| Bi, H | 2 |
| Qin, Z | 2 |
| Wang, Q | 1 |
| Walsh, M | 1 |
| Choi, J | 1 |
| Han, YN | 1 |
| Rha, EY | 2 |
| Kang, HJ | 1 |
| Kim, KJ | 1 |
| Park, IK | 2 |
| Kim, HJ | 2 |
| Rhie, JW | 2 |
| Zhuang, Z | 1 |
| Li, Y | 2 |
| Wei, X | 1 |
| Kuang, J | 1 |
| An, P | 1 |
| Li, W | 1 |
| Abedini, R | 1 |
| Sasani, P | 1 |
| Mahmoudi, HR | 1 |
| Nasimi, M | 1 |
| Teymourpour, A | 1 |
| Shadlou, Z | 1 |
| Sabry, HH | 1 |
| Abdel Rahman, SH | 1 |
| Hussein, MS | 1 |
| Sanad, RR | 1 |
| Abd El Azez, TA | 1 |
| Ledon, JA | 1 |
| Savas, J | 1 |
| Franca, K | 1 |
| Chacon, A | 1 |
| Nouri, K | 1 |
| Boggio, RF | 1 |
| Boggio, LF | 1 |
| Galvão, BL | 1 |
| Machado-Santelli, GM | 1 |
| Yang, SY | 2 |
| Yang, JY | 3 |
| Hsiao, YC | 2 |
| Wang, R | 1 |
| Mao, Y | 1 |
| Zhang, Z | 1 |
| Li, Z | 1 |
| Chen, J | 1 |
| Cen, Y | 1 |
| Verhiel, S | 1 |
| Piatkowski de Grzymala, A | 1 |
| van der Hulst, R | 1 |
| Kim, YH | 1 |
| Kim, TJ | 1 |
| Yoo, G | 1 |
| Su, L | 1 |
| Fu, L | 1 |
| Yang, F | 1 |
| Zhang, M | 1 |
| Hu, D | 1 |
| Chuang, SS | 1 |
| Xu, SJ | 1 |
| Teng, JY | 1 |
| Xie, J | 1 |
| Shen, MQ | 1 |
| Chen, DM | 1 |
| Juckett, G | 1 |
| Hartman-Adams, H | 1 |
| Huang, CY | 1 |
| Brudnik, U | 1 |
| Podolec-Rubiś, M | 1 |
| Wojas-Pelc, A | 1 |
| Lee, RC | 1 |
| Doong, H | 1 |
| Jellema, AF | 1 |
| Wang, Z | 1 |
| Guo, S | 1 |
| Lu, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessing and Improving Patient Knowledge About Keloids[NCT01176877] | 40 participants (Actual) | Interventional | 2010-08-31 | Completed | |||
| Intra-lesional ACE Inhibitor for Treatment of Hypertrophic Scars[NCT05259137] | Phase 2/Phase 3 | 30 participants (Anticipated) | Interventional | 2023-08-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
All subjects completed a written questionnaire to assess knowledge about keloid scars before an educational lecture about keloids, immediately after the educational lecture about keloids, and 3 months after the educational lecture about keloids. This written questionnaire to assess knowledge about keloid scars contained 19 questions related to risk factors for developing keloid scars, keloid scar prevention, and keloid scar treatment. A correct response to a question was awarded 1 point and all correct responses were summed to achieve a total score. Possible total score ranged from 0 to 19. A score of 0 is associated with worse knowledge about keloid scars and a score of 19 is associated with better knowledge about keloid scars. (NCT01176877)
Timeframe: immediately before and after a 5 minute educational lecture
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Pre-educational lecture score | Immediate post-educational lecture score | |
| Keloid Scar | 12.9 | 18.3 |
All subjects completed a written questionnaire to assess knowledge about keloid scars before an educational lecture about keloids, immediately after the educational lecture about keloids, and 3 months after the educational lecture about keloids. This written questionnaire to assess knowledge about keloid scars contained 19 questions related to risk factors for developing keloid scars, keloid scar prevention, and keloid scar treatment. A correct response to a question was awarded 1 point and all correct responses were summed to achieve a total score. Possible total score ranged from 0 to 19. A score of 0 is associated with worse knowledge about keloid scars and a score of 19 is associated with better knowledge about keloid scars. (NCT01176877)
Timeframe: before and 3 months after a 5 minute educational lecture
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Pre-educational lecture score | 3 months post-educational lecture score | |
| Keloid Scars | 13.2 | 16.8 |
11 reviews available for verapamil and Cicatrix, Hypertrophic
| Article | Year |
|---|---|
Laser therapy for treating hypertrophic and keloid scars.
Topics: Adrenal Cortex Hormones; Adult; Aluminum; Atrophy; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Di | 2022 |
Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as T | 2023 |
The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis.
Topics: Calcium Channel Blockers; Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional | 2020 |
Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; Verapami | 2020 |
Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as T | 2021 |
The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
Topics: Atrophy; Burns; Cicatrix, Hypertrophic; Culture Media; Fluorouracil; Humans; Injections, Intralesion | 2021 |
Comparative efficacy and safety of verapamil and triamcinolone in keloid and hypertrophic scar treatment: a meta-analysis.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone | 2021 |
Intralesional treatment for keloids and hypertrophic scars: a review.
Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Antimetabolites; Bleomycin; Calcium Channel Bl | 2013 |
Mechanism of Action, Efficacy, and Adverse Events of Calcium Antagonists in Hypertrophic Scars and Keloids: A Systematic Review.
Topics: Calcium Channel Blockers; Cicatrix, Hypertrophic; Humans; Keloid; Verapamil | 2015 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
[Therapeutic problems connected with keloid treatment--new treatment possibilities].
Topics: Cicatrix, Hypertrophic; Dermatologic Agents; Fibroblasts; Humans; Keloid; Mitomycin; Scleroderma, Lo | 2006 |
5 trials available for verapamil and Cicatrix, Hypertrophic
| Article | Year |
|---|---|
Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
THE USAGE OF RADIOFREQUENCY ABLATION FOR TREATMENT OF KELOIDS AND HYPERTROPHIC SCARS.
Topics: Adult; Catheter Ablation; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Fluorouracil; H | 2019 |
Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial.
Topics: Adolescent; Adult; Calcium Channel Blockers; Cicatrix, Hypertrophic; Factor Analysis, Statistical; F | 2018 |
Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids.
Topics: Adolescent; Adult; Calcium Channel Blockers; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans | 2014 |
[Comparison of the mechanisms of intralesional steroid, interferon or verapamil injection in the treatment of proliferative scars].
Topics: Adolescent; Adult; Apoptosis; Child; Cicatrix, Hypertrophic; Female; Humans; Interferon alpha-2; Int | 2009 |
15 other studies available for verapamil and Cicatrix, Hypertrophic
| Article | Year |
|---|---|
Co-delivery of triamcinolone acetonide and verapamil for synergistic treatment of hypertrophic scars via carboxymethyl chitosan and Bletilla striata polysaccharide-based microneedles.
Topics: Chitosan; Cicatrix, Hypertrophic; Humans; Polysaccharides; Triamcinolone Acetonide; Verapamil | 2022 |
Response to Letter to the Editor: Comments on "Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids".
Topics: Burns; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; V | 2020 |
Comments on "Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids".
Topics: Burns; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; V | 2020 |
Commentary on: Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as T | 2021 |
Verapamil-containing silicone gel reduces scar hypertrophy.
Topics: Animals; Cicatrix, Hypertrophic; Collagen; Hypertrophy; Rabbits; Silicone Gels; Verapamil | 2021 |
The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Combined Modality Therapy; Dose Fractionation, Radi | 2019 |
Topical verapamil as a scar modulator.
Topics: Abdominoplasty; Administration, Topical; Adult; Aged; Calcium Channel Blockers; Cicatrix, Hypertroph | 2014 |
Comparison of combination therapy (steroid, calcium channel blocker, and interferon) with steroid monotherapy for treating human hypertrophic scars in an animal model.
Topics: Adult; Animals; Calcium Channel Blockers; Cicatrix, Hypertrophic; Disease Models, Animal; Drug Thera | 2015 |
Role of verapamil in preventing and treating hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Databases, Factual; Humans; Keloid; Verapamil | 2016 |
Topical Application of a Silicone Gel Sheet with Verapamil Microparticles in a Rabbit Model of Hypertrophic Scar.
Topics: Administration, Topical; Animals; Cell-Derived Microparticles; Cicatrix, Hypertrophic; Disease Model | 2016 |
Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar.
Topics: Actin Cytoskeleton; Adolescent; Adult; Antineoplastic Agents; ATP Binding Cassette Transporter, Subf | 2017 |
A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study.
Topics: Adolescent; Adult; Animals; Burns; Calcium Channel Blockers; Child; Child, Preschool; Cicatrix; Cica | 2017 |
The effect of combined steroid and calcium channel blocker injection on human hypertrophic scars in animal model: a new strategy for the treatment of hypertrophic scars.
Topics: Animals; Burns; Calcium Channel Blockers; Cell Proliferation; Cicatrix, Hypertrophic; Decorin; Disea | 2010 |
The response of burn scars to intralesional verapamil. Report of five cases.
Topics: Adolescent; Adult; Burns; Cicatrix, Hypertrophic; Female; Humans; Injections, Intralesional; Male; M | 1994 |
[The biological effect of verapamil on hypertrophic scar fibroblast].
Topics: Adolescent; Calcium Channel Blockers; Cell Division; Cells, Cultured; Child; Child, Preschool; Cicat | 2001 |