verapamil has been researched along with Chronic Primary Open Angle Glaucoma in 8 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As glaucoma is one of the most significant causes of blindness, and administration of calcium channel blockers is effective in reducing intraocular pressure (IOP) in rabbits and patients with normotensive glaucoma, we administered topical verapamil 0." | 5.14 | Comparative study of topical application of timolol and verapamil in patients with glaucoma within 6 months. ( Boloorian, AA; Kianoush, S; Shayegan, MR, 2009) |
| "There were no significant differences in preoperative mean intraocular pressure, mean number of medications, and glaucoma severity between the verapamil and placebo groups." | 5.09 | Topical verapamil in glaucoma filtration surgery. ( Hughes, BA; Juzych, MS; Kardasis, CT; Keole, NS; Kim, C; Shin, DH, 2001) |
| "Vasospasm has been implicated as a cause of amaurosis fugax, which can be controlled by administration of the calcium channel blockers nifedipine or verapamil." | 3.69 | Recovery from ocular ischemic syndrome after treatment with verapamil. ( Beckman, RL; Winterkorn, JM, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shayegan, MR | 1 |
| Boloorian, AA | 1 |
| Kianoush, S | 1 |
| Hueber, A | 1 |
| Esser, JM | 1 |
| Kociok, N | 1 |
| Welsandt, G | 1 |
| Lüke, C | 1 |
| Roters, S | 1 |
| Esser, PJ | 1 |
| Ettl, A | 1 |
| Daxer, A | 1 |
| Hofmann, U | 1 |
| Netland, PA | 1 |
| Chaturvedi, N | 1 |
| Dreyer, EB | 1 |
| Winterkorn, JM | 1 |
| Beckman, RL | 1 |
| Liu, S | 1 |
| Araujo, SV | 1 |
| Spaeth, GL | 1 |
| Katz, LJ | 1 |
| Smith, M | 1 |
| Shin, DH | 1 |
| Kardasis, CT | 1 |
| Kim, C | 1 |
| Juzych, MS | 1 |
| Hughes, BA | 1 |
| Keole, NS | 1 |
| Pringle, SD | 1 |
| MacEwen, CJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multidrug Resistance After Trabeculectomy With Mitomycin C[NCT00449631] | 30 participants | Observational | Completed | ||||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for verapamil and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Comparative study of topical application of timolol and verapamil in patients with glaucoma within 6 months.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Metho | 2009 |
Lack of effect of calcium channel blockers on open-angle glaucoma.
Topics: Aged; Calcium Channel Blockers; Diltiazem; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middl | 1996 |
Topical verapamil in glaucoma filtration surgery.
Topics: Administration, Topical; Aged; Calcium Channel Blockers; Chemotherapy, Adjuvant; Chronic Disease; Do | 2001 |
5 other studies available for verapamil and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Mitomycin C induces multidrug resistance in glaucoma surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alkylating Agents; ATP Binding Cassette Transporter, Sub | 2008 |
Calcium channel blockers in the management of low-tension and open-angle glaucoma.
Topics: Administration, Topical; Animals; Aqueous Humor; Glaucoma, Open-Angle; Half-Life; Humans; Intraocula | 1993 |
Calcium channel blockers in the management of low-tension and open-angle glaucoma.
Topics: Administration, Oral; Aged; Aged, 80 and over; Calcium Channel Blockers; Diltiazem; Female; Follow-U | 1993 |
Recovery from ocular ischemic syndrome after treatment with verapamil.
Topics: Aged; Aged, 80 and over; Blindness; Calcium Channel Blockers; Chronic Disease; Eye; Glaucoma, Open-A | 1995 |
Severe bradycardia due to interaction of timolol eye drops and verapamil.
Topics: Bradycardia; Drug Interactions; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ophthalmic Solution | 1987 |