Page last updated: 2024-10-24

verapamil and Cholestasis

verapamil has been researched along with Cholestasis in 2 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Research Excerpts

ExcerptRelevanceReference
"Verapamil was used as a P-gp specific inhibitor and acetylaminofluorene (AAF) as a P-gp inducer."1.30Effect of pharmacological modulation of liver P-glycoproteins on cyclosporin A biliary excretion and cholestasis: a study in isolated perfused rat liver. ( Alvaro, D; Benedetti, A; Bini, A; Delle Monache, MD; Di Cosimo, E; Fraioli, F; Francia, C; Gigliozzi, A; Jezequel, AM; Marucci, L; Papa, E, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kolts, BE1
Langfitt, M1
Delle Monache, MD1
Gigliozzi, A1
Benedetti, A1
Marucci, L1
Bini, A1
Francia, C1
Papa, E1
Di Cosimo, E1
Fraioli, F1
Jezequel, AM1
Alvaro, D1

Other Studies

2 other studies available for verapamil and Cholestasis

ArticleYear
Drugs and the liver.
    Comprehensive therapy, 1984, Volume: 10, Issue:12

    Topics: Acetaminophen; Adult; Aspirin; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liv

1984
Effect of pharmacological modulation of liver P-glycoproteins on cyclosporin A biliary excretion and cholestasis: a study in isolated perfused rat liver.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:11

    Topics: 2-Acetylaminofluorene; Animals; ATP Binding Cassette Transporter, Subfamily B; Bile; Cholestasis; Cy

1999