verapamil has been researched along with Cerebral Infarction in 12 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Verapamil is a widely used calcium channel blocker." | 5.27 | Cerebral infarction associated with oral verapamil overdose. ( Samniah, N; Schlaeffer, F, 1988) |
| " A second combination compound including verapamil 180 mg and trandolapril 2 mg daily was added 5 days prior to hospitalisation due to insufficient control of arterial hypertension." | 3.72 | [Lethal polypharmacy in a patient with arterial hypertension]. ( Diethelm, M; Joerger, M, 2004) |
| "Levemopamil, a novel calcium channel blocker with antagonistic action on serotonin S2-receptors has been reported to be a promising compound for therapy in cerebral ischemia." | 3.69 | Failure of levemopamil to improve histological outcome following temporary occlusion of the middle cerebral artery in cats. ( Croul, S; Gomi, S; Greenberg, JH; Reivich, M, 1995) |
| "Cerebral ischemic model was made by middle cerebral artery occlusion (MCAO)." | 1.35 | Aberration of L-type calcium channel in cardiac myocytes is one of the mechanisms of arrhythmia induced by cerebral ischemia. ( Du, J; Pan, G; Sun, L; Wang, L; Yang, B; Zhang, G; Zhang, Y, 2008) |
| "(S)-Emopamil is a calcium channel blocker of the phenylalkylamine class, having potent serotonin S2 antagonistic properties and high blood-brain barrier penetrability." | 1.28 | Postischemic (S)-emopamil therapy ameliorates focal ischemic brain injury in rats. ( Busto, R; Dietrich, WD; Duncan, RC; Ginsberg, MD; Morikawa, E, 1991) |
| "(S)-Emopamil is a novel calcium channel blocker of the phenylalkylamine class, with superior blood-brain permeability and potent serotonin S2 antagonist activity." | 1.27 | (S)-emopamil, a novel calcium channel blocker and serotonin S2 antagonist, markedly reduces infarct size following middle cerebral artery occlusion in the rat. ( Dietrich, WD; Ginsberg, MD; Nakayama, H, 1988) |
| "Verapamil is a widely used calcium channel blocker." | 1.27 | Cerebral infarction associated with oral verapamil overdose. ( Samniah, N; Schlaeffer, F, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maniskas, ME | 1 |
| Roberts, JM | 1 |
| Aron, I | 1 |
| Fraser, JF | 1 |
| Bix, GJ | 1 |
| Sun, L | 1 |
| Du, J | 1 |
| Zhang, G | 1 |
| Zhang, Y | 1 |
| Pan, G | 1 |
| Wang, L | 1 |
| Yang, B | 1 |
| Yui, J | 1 |
| Hatori, A | 1 |
| Kawamura, K | 1 |
| Yanamoto, K | 1 |
| Yamasaki, T | 1 |
| Ogawa, M | 1 |
| Yoshida, Y | 1 |
| Kumata, K | 1 |
| Fujinaga, M | 1 |
| Nengaki, N | 1 |
| Fukumura, T | 1 |
| Suzuki, K | 1 |
| Zhang, MR | 1 |
| Joerger, M | 1 |
| Diethelm, M | 1 |
| Elger, B | 1 |
| Seega, J | 1 |
| Raschack, M | 1 |
| Gomi, S | 1 |
| Greenberg, JH | 1 |
| Croul, S | 1 |
| Reivich, M | 1 |
| Yamamoto, YL | 1 |
| Ueda, T | 1 |
| Shimauchi, M | 1 |
| Diksic, M | 1 |
| Morikawa, E | 1 |
| Ginsberg, MD | 2 |
| Dietrich, WD | 2 |
| Duncan, RC | 1 |
| Busto, R | 1 |
| Handa, J | 1 |
| Shiino, A | 1 |
| Kidooka, M | 1 |
| Nakayama, H | 1 |
| Samniah, N | 1 |
| Schlaeffer, F | 1 |
| Tomberg, TA | 1 |
| Miagi, MA | 1 |
| Rekand, TE | 1 |
| Alilender, MV | 1 |
| Iaanson, IaKh | 1 |
1 review available for verapamil and Cerebral Infarction
| Article | Year |
|---|---|
[Ca antagonists in neurosurgical practice].
Topics: Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cerebral Infarction; Disease Models, Anim | 1990 |
11 other studies available for verapamil and Cerebral Infarction
| Article | Year |
|---|---|
Stroke neuroprotection revisited: Intra-arterial verapamil is profoundly neuroprotective in experimental acute ischemic stroke.
Topics: Acute Disease; Animals; Apoptosis; Behavior, Animal; Brain Ischemia; Calcium Channel Blockers; Cell | 2016 |
Aberration of L-type calcium channel in cardiac myocytes is one of the mechanisms of arrhythmia induced by cerebral ischemia.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Brain Ischemia; Caffeine; Calcium; Calcium Channel | 2008 |
Visualization of early infarction in rat brain after ischemia using a translocator protein (18 kDa) PET ligand [11C]DAC with ultra-high specific activity.
Topics: Acetamides; Animals; Autoradiography; Blood-Brain Barrier; Brain; Brain Ischemia; Carbon Radioisotop | 2011 |
[Lethal polypharmacy in a patient with arterial hypertension].
Topics: Aged; Aged, 80 and over; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agent | 2004 |
Oedema reduction by levemopamil in focal cerebral ischaemia of spontaneously hypertensive rats studied by magnetic resonance imaging.
Topics: Animals; Body Temperature; Brain Edema; Calcium Channel Blockers; Cerebral Infarction; Dose-Response | 1994 |
Failure of levemopamil to improve histological outcome following temporary occlusion of the middle cerebral artery in cats.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Cats; Cerebral Arteries; Cerebral Infarcti | 1995 |
Efficacy of bypass between extracerebral artery and cerebral vein with retrograde verapamil infusion into focal cerebral ischemic tissue in rats.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Cerebral Infarction; Cerebral Revascularization; Cereb | 1991 |
Postischemic (S)-emopamil therapy ameliorates focal ischemic brain injury in rats.
Topics: Animals; Blood Pressure; Brain; Cerebral Arteries; Cerebral Infarction; Ischemic Attack, Transient; | 1991 |
(S)-emopamil, a novel calcium channel blocker and serotonin S2 antagonist, markedly reduces infarct size following middle cerebral artery occlusion in the rat.
Topics: Animals; Calcium Channel Blockers; Cerebral Arteries; Cerebral Infarction; Male; Rats; Rats, Inbred | 1988 |
Cerebral infarction associated with oral verapamil overdose.
Topics: Adult; Cerebral Infarction; Female; Hemiplegia; Humans; Parietal Lobe; Suicide, Attempted; Temporal | 1988 |
[Effect of calcium antagonists of the verapamil type on regional cerebral blood flow and bioelectric activity of the brain in patients with cerebral infarction].
Topics: Action Potentials; Aged; Brain; Cerebral Infarction; Cerebrovascular Circulation; Electroencephalogr | 1988 |