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verapamil and Cerebellar Diseases

verapamil has been researched along with Cerebellar Diseases in 2 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Cerebellar Diseases: Diseases that affect the structure or function of the cerebellum. Cardinal manifestations of cerebellar dysfunction include dysmetria, GAIT ATAXIA, and MUSCLE HYPOTONIA.

Research Excerpts

ExcerptRelevanceReference
"We have used the model of L-2-chloropropionic acid (L-CPA)-induced selective cerebellar granule necrosis to study excitatory amino acid-induced necrotic cell death in vivo produced by the activation of N-methyl-D-aspartate (NMDA) receptors."7.69L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists. ( Gyte, A; Moores, R; Pitts, M; Smith, JC; Upton, R; Widdowson, PS; Wyatt, I, 1997)
"We have used the model of L-2-chloropropionic acid (L-CPA)-induced selective cerebellar granule necrosis to study excitatory amino acid-induced necrotic cell death in vivo produced by the activation of N-methyl-D-aspartate (NMDA) receptors."3.69L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists. ( Gyte, A; Moores, R; Pitts, M; Smith, JC; Upton, R; Widdowson, PS; Wyatt, I, 1997)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liesi, P1
Wright, JM1
Krauthamer, V1
Widdowson, PS1
Gyte, A1
Upton, R1
Smith, JC1
Pitts, M1
Moores, R1
Wyatt, I1

Other Studies

2 other studies available for verapamil and Cerebellar Diseases

ArticleYear
BAPTA-AM and ethanol protect cerebellar granule neurons from the destructive effect of the weaver gene.
    Journal of neuroscience research, 1997, Jun-15, Volume: 48, Issue:6

    Topics: Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels

1997
L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists.
    Archives of toxicology, 1997, Volume: 71, Issue:12

    Topics: Animals; Aspartic Acid; Body Weight; Calcium Channel Blockers; Cerebellar Diseases; Cerebellum; Drug

1997