verapamil has been researched along with Cell Transformation, Neoplastic in 5 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of a calcium channel blocker, verapamil, on intracellular uptake and cytotoxicity of anthracyclines in vitro was studied on leukemic cells from 32 patients with acute non-lymphoblastic leukemia." | 3.67 | Effects of verapamil on uptake and in vitro toxicity of anthracyclines in human leukemic blast cells. ( Paul, C; Sundman-Engberg, B; Tidefelt, U, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spalletti-Cernia, D | 1 |
| D'Agnano, I | 1 |
| Sorrentino, R | 1 |
| Zupi, G | 1 |
| Vecchio, G | 1 |
| Portella, G | 1 |
| Laccetti, P | 1 |
| Slater, LM | 1 |
| Murray, SL | 1 |
| Wetzel, MW | 1 |
| Wisdom, RM | 1 |
| DuVall, EM | 1 |
| Alfonso-De Matte, MY | 1 |
| Moses-Soto, H | 1 |
| Kruk, PA | 1 |
| Weber, JM | 1 |
| Sircar, S | 1 |
| Horvath, J | 1 |
| Dion, P | 1 |
| Tidefelt, U | 1 |
| Sundman-Engberg, B | 1 |
| Paul, C | 1 |
5 other studies available for verapamil and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Verapamil reverts resistance to drug-induced apoptosis in Ki-ras-transformed cells by altering the cell membrane and the mitochondrial transmembrane potentials.
Topics: Animals; Apoptosis; Cell Line; Cell Membrane; Cell Survival; Cell Transformation, Neoplastic; Doxoru | 2002 |
Verapamil restoration of daunorubicin responsiveness in daunorubicin-resistant Ehrlich ascites carcinoma.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Transformation, Neoplastic; Daunorubicin; DNA; Dose-Response | 1982 |
Calcium-mediated telomerase activity in ovarian epithelial cells.
Topics: Cadmium; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; Chromium; Epithelial Cells; Fema | 2002 |
Non-p-glycoprotein-mediated multidrug resistance in detransformed rat cells selected for resistance to methylglyoxal bis(guanylhydrazone).
Topics: Adult; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood | 1989 |
Effects of verapamil on uptake and in vitro toxicity of anthracyclines in human leukemic blast cells.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Body Fluids; Cell Transformatio | 1988 |