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verapamil and Cataract

verapamil has been researched along with Cataract in 7 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"To investigate the efficacy of verapamil eye drops for inhibition of diabetic cataract in rats."7.72Inhibition of experimental diabetic cataract by topical administration of RS-verapamil hydrochloride. ( Daxer, A; Ettl, A; Göttinger, W; Schmid, E, 2004)
"Verapamil effectively decreased the lens calcium concentration, which is accepted as the key element in radiation cataractogenesis."7.70The effect of verapamil in the prevention of radiation-induced cataract. ( Atahan, IL; Cengiz, M; Gürkaynak, M; Kiliç, K; Totan, Y, 1999)
"The purpose of the present study was to examine the effects on cataractogenesis of daily sc administration of the Ca2+ antagonist drug verapamil to diabetic rats."7.67Cataract formation is prevented by administration of verapamil to diabetic rats. ( Afzal, N; Dhalla, NS; Eckhert, CD; Kroeger, EA; Kutryk, MJ; Lockwood, MK; Pierce, GN, 1989)
"To investigate the efficacy of verapamil eye drops for inhibition of diabetic cataract in rats."3.72Inhibition of experimental diabetic cataract by topical administration of RS-verapamil hydrochloride. ( Daxer, A; Ettl, A; Göttinger, W; Schmid, E, 2004)
"Verapamil effectively decreased the lens calcium concentration, which is accepted as the key element in radiation cataractogenesis."3.70The effect of verapamil in the prevention of radiation-induced cataract. ( Atahan, IL; Cengiz, M; Gürkaynak, M; Kiliç, K; Totan, Y, 1999)
"The purpose of the present study was to examine the effects on cataractogenesis of daily sc administration of the Ca2+ antagonist drug verapamil to diabetic rats."3.67Cataract formation is prevented by administration of verapamil to diabetic rats. ( Afzal, N; Dhalla, NS; Eckhert, CD; Kroeger, EA; Kutryk, MJ; Lockwood, MK; Pierce, GN, 1989)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ettl, A1
Daxer, A1
Göttinger, W1
Schmid, E1
Gupta, PD1
Johar, K1
Vasavada, A1
Kametaka, S1
Kasahara, T1
Ueo, M1
Takenaka, M1
Saito, M1
Sakamoto, K1
Nakahara, T1
Ishii, K1
Bhatnagar, A1
Ansari, NH1
Wang, L1
Khanna, P1
Wang, C1
Srivastava, SK1
Cekic, O1
Bardak, Y1
Cengiz, M1
Gürkaynak, M1
Atahan, IL1
Kiliç, K1
Totan, Y1
Pierce, GN1
Afzal, N1
Kroeger, EA1
Lockwood, MK1
Kutryk, MJ1
Eckhert, CD1
Dhalla, NS1

Reviews

1 review available for verapamil and Cataract

ArticleYear
Causative and preventive action of calcium in cataracto-genesis.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:10

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cataract; Cell Death; Epithelial Cell

2004

Other Studies

6 other studies available for verapamil and Cataract

ArticleYear
Inhibition of experimental diabetic cataract by topical administration of RS-verapamil hydrochloride.
    The British journal of ophthalmology, 2004, Volume: 88, Issue:1

    Topics: Animals; Calcium Channel Blockers; Cataract; Diabetes Mellitus, Experimental; Disease Progression; I

2004
Effect of nifedipine on severe experimental cataract in diabetic rats.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:4

    Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Cataract; Diabetes Me

2008
Calcium-mediated disintegrative globulization of isolated ocular lens fibers mimics cataractogenesis.
    Experimental eye research, 1995, Volume: 61, Issue:3

    Topics: Adenosine Monophosphate; Animals; Calcium; Cataract; Glutathione; In Vitro Techniques; Lanthanum; Le

1995
Lenticular calcium, magnesium, and iron levels in diabetic rats and verapamil effect.
    Ophthalmic research, 1998, Volume: 30, Issue:2

    Topics: Animals; Blood Glucose; Calcium; Calcium Channel Blockers; Cataract; Diabetes Mellitus, Experimental

1998
The effect of verapamil in the prevention of radiation-induced cataract.
    International journal of radiation oncology, biology, physics, 1999, Feb-01, Volume: 43, Issue:3

    Topics: Animals; Calcium Channel Blockers; Cataract; Female; Radiation Injuries, Experimental; Rats; Rats, W

1999
Cataract formation is prevented by administration of verapamil to diabetic rats.
    Endocrinology, 1989, Volume: 125, Issue:2

    Topics: Animals; Calcium; Cataract; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diltiazem; Inject

1989