Page last updated: 2024-10-24

verapamil and Cardiovascular Diseases

verapamil has been researched along with Cardiovascular Diseases in 73 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"The Bergamo Nephrologic Diabetes Complications Trial-B was a multicentre, prospective, double-blind, parallel-group trial comparing renal and cardiovascular outcomes in 281 hypertensive type 2 diabetes patients with microalbuminuria randomized to at least 2-year VeraTran (verapamil/trandolapril 180 mg/2 mg daily) or trandolapril (2 mg daily, identical image) treatment."9.15Effects of verapamil added-on trandolapril therapy in hypertensive type 2 diabetes patients with microalbuminuria: the BENEDICT-B randomized trial. ( Bossi, A; Chiurchiu, C; Cravedi, P; Ene-Iordache, B; Fassi, A; Gaspari, F; Gherardi, G; Iliev, IP; Ilieva, A; Motterlini, N; Perna, A; Remuzzi, G; Rubis, N; Ruggenenti, P; Trevisan, R, 2011)
"The Bergamo Nephrologic Diabetes Complications Trial-B was a multicentre, prospective, double-blind, parallel-group trial comparing renal and cardiovascular outcomes in 281 hypertensive type 2 diabetes patients with microalbuminuria randomized to at least 2-year VeraTran (verapamil/trandolapril 180 mg/2 mg daily) or trandolapril (2 mg daily, identical image) treatment."5.15Effects of verapamil added-on trandolapril therapy in hypertensive type 2 diabetes patients with microalbuminuria: the BENEDICT-B randomized trial. ( Bossi, A; Chiurchiu, C; Cravedi, P; Ene-Iordache, B; Fassi, A; Gaspari, F; Gherardi, G; Iliev, IP; Ilieva, A; Motterlini, N; Perna, A; Remuzzi, G; Rubis, N; Ruggenenti, P; Trevisan, R, 2011)
"Based on over 4,000 person-years of observation, patients with acute myocardial infarction (MI) treated with verapamil had a decreased risk of nonfatal reinfarction compared with placebo (relative risk 0."4.80Verapamil use in patients with cardiovascular disease: an overview of randomized trials. ( Faich, G; Makuch, R; Pepine, CJ, 1998)
" Verapamil is extremely effective in patients with supraventricular tachyarrhythmias, hypertrophic cardiomyopathy, and the various anginal syndromes, but it appears to be ineffective or possibly even deleterious in those with pulmonary hypertension, congestive heart failure of any cause, and Raynaud's phenomenon or disease."4.77Calcium antagonists in patients with cardiovascular disease. Current perspectives. ( Hillis, LD; Winniford, MD, 1985)
"Verapamil (VER) is a calcium channel blocker that is widely used to treat various cardiovascular diseases and is also effective in migraine prophylaxis."3.91Analytical techniques for the determination of verapamil in biological samples and dosage forms: an overview. ( Jouyban, A; Pourkarim, F; Rahimpour, E, 2019)
"Verapamil, which has profound electrophysiologic effects on the slow inward current, is emerging as a valuable antiarrhythmic agent."3.75Calcium channel blocking agents in the treatment of cardiovascular disorders. Part I: Basic and clinical electrophysiologic effects. ( Antman, EM; Braunwald, E; Muller, JE; Stone, PH, 1980)
"In a prospective study of 809 patients with stable angina pectoris randomized to receive metoprolol or verapamil, a subgroup of 69 diabetic patients was compared with non-diabetic patients with respect to the risk of cardiovascular (CV) death, non-fatal myocardial infarction (MI) and revascularization."3.73The impact of diabetes or elevated fasting blood glucose on cardiovascular prognosis in patients with stable angina pectoris. ( Björkander, I; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N, 2005)
"Fibrinogen and WBC were independent predictors of CV death or non-fatal MI as well as disease progression leading to revascularization in patients with stable angina pectoris."2.69Inflammatory and hemostatic markers in relation to cardiovascular prognosis in patients with stable angina pectoris. Results from the APSIS study. The Angina Prognosis Study in Stockholm. ( Björkander, I; Forslund, L; Håkan Wallén, N; Held, C; Hjemdahl, P; Rehnqvist, N; Wiman, B, 2000)
" Another side effect is constipation, which is frequent after verapamil."2.38Calcium antagonists--assessment of side effects. ( Thulin, T, 1990)
"Verapamil was more often associated with conduction problems (up to 9%) and dyspnea or heart failure (up to 8%)."2.37Review of the cardiovascular adversity of the calcium antagonist beta-blocker combination: implications for antihypertensive therapy. ( Brouwer, RM; Bühler, FR; Follath, F, 1985)
" Diltiazem with a beta-blocker is usually well-tolerated, with a low incidence of adverse effects, similar to the experience with diltiazem monotherapy."2.37Combined use of calcium-channel and beta-adrenergic blockers for the treatment of chronic stable angina. Rationale, efficacy, and adverse effects. ( Parisi, AF; Strauss, WE, 1988)
"Incident cancer events were gathered from a nationwide registry of hospitalisation data and from a specialised cancer centre in the Rotterdam region."1.32Verapamil is associated with an increased risk of cancer in the elderly: the Rotterdam study. ( Beiderbeck-Noll, AB; Coebergh, JW; Herings, RM; Hofman, A; Leufkens, HG; Stricker, BH; Sturkenboom, MC; van der Linden, PD, 2003)
" Dosage levels and corresponding mean trough levels (+/- S."1.28Requirements for drug monitoring of verapamil: experience from an unselected group of patients with cardiovascular disease. ( Husum, D; Jensen, G; Johnsen, A, 1990)
"They also have great potential for the treatment of hypertension, cerebrovascular disorders, and Raynaud's phenomenon."1.27Calcium channel blocking drugs. Part II: Clinical applications. ( Brill, DM; Fozzard, HA, 1985)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199034 (46.58)18.7374
1990's16 (21.92)18.2507
2000's12 (16.44)29.6817
2010's11 (15.07)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pourkarim, F1
Rahimpour, E1
Jouyban, A1
Carvalho, DS1
de Almeida, AA1
Borges, AF1
Vannucci Campos, D1
McDonough, CW1
Gong, Y3
Padmanabhan, S1
Burkley, B1
Langaee, TY2
Melander, O1
Pepine, CJ5
Dominiczak, AF1
Cooper-Dehoff, RM2
Johnson, JA3
Cerda, A1
Hirata, RD1
Hirata, MH1
Baryshnikova, GA1
Chorbinskayva, SA1
Stepanova, II1
Blochina, OE1
Zverkov, IV1
Maslovskyi, LV1
Korchazhkina, NB1
Maslennikova, OM1
Beitelshees, AL1
Navare, H1
Wang, D2
Wessel, J1
Moss, JI1
Sadee, W2
Schork, NJ1
Sawatzki, M1
Kummer, O1
Krähenbühl, S1
Siegemund, M1
Ruggenenti, P2
Fassi, A1
Ilieva, A1
Iliev, IP2
Chiurchiu, C1
Rubis, N2
Gherardi, G1
Ene-Iordache, B2
Gaspari, F2
Perna, A2
Cravedi, P1
Bossi, A2
Trevisan, R2
Motterlini, N2
Remuzzi, G2
Schmidt, M1
Johansen, MB1
Robertson, DJ1
Maeng, M1
Kaltoft, A1
Jensen, LO1
Tilsted, HH1
Bøtker, HE1
Sørensen, HT1
Baron, JA1
Pirker, S1
Baumgartner, C1
Papp, AC1
Pinsonneault, JK1
Newman, LC1
Kumari, M1
Hingorani, AD1
Talmud, PJ1
Shah, S1
Humphries, SE1
Porrini, E1
Ilieva, AP1
Dodesini, AR1
Sampietro, G1
Capitoni, E1
Caracciolo, VJ1
Shaefer, BM1
Charney, P1
Beiderbeck-Noll, AB1
Sturkenboom, MC1
van der Linden, PD1
Herings, RM1
Hofman, A1
Coebergh, JW1
Leufkens, HG1
Stricker, BH1
Held, C3
Björkander, I2
Forslund, L3
Rehnqvist, N3
Hjemdahl, P3
El Haouari, M1
Bnouham, M1
Bendahou, M1
Aziz, M1
Ziyyat, A1
Legssyer, A1
Mekhfi, H1
Almquist, T1
Sica, DA1
Mancia, G1
Messerli, F2
Bakris, G1
Zhou, Q1
Champion, A1
Gilani, AH1
Bashir, S1
Khan, AU1
Karlsberg, RP3
Ellrodt, AG1
Singh, BN2
Fossati, C1
Guistiniani, S1
Ellrodt, G1
Chew, CY1
Antman, EM3
Stone, PH2
Muller, JE2
Braunwald, E2
Fleckenstein, A1
Strubelt, O1
Rossi, LP1
Foster, BC1
Tritthart, HA1
Assey, ME1
Dargie, H1
Rowland, E1
Krikler, D2
Aronow, WS1
Chia, BL1
Ee, BK1
Tan, AT1
Choo, M1
Schwartz, DJ1
Wasserstrom, JA1
Fozzard, HA2
Hogan, L1
Lancelin, B1
Blanchard, D1
Aziza, JP1
Guermonprez, JL1
Maurice, P1
Kline, JA1
Tomaszewski, CA1
Schroeder, JD1
Raymond, RM1
Salerno, SM1
Zugibe, FT1
Tonkin, A1
Frewin, D1
Chatelain, P1
Mouton, J1
Feys, G1
Laruel, A1
Manning, AS1
Conti, CR1
Laragh, JH1
Pepine, C1
Sleight, P2
Tuncok, Y1
Apaydin, S1
Kalkan, S1
Ates, M1
Guven, H1
Black, HR1
Elliott, WJ2
Neaton, JD1
Grandits, G1
Grambsch, P1
Grimm, RH1
Hansson, L1
Lacoucière, Y1
Muller, J1
Weber, MA1
White, WB1
Williams, G1
Wittes, J1
Zanchetti, A1
Fakouhi, TD1
Faich, G1
Makuch, R1
Håkan Wallén, N1
Wiman, B1
Tkaczewski, W1
Goch, JH1
Tam, IM1
Wandres, DL1
Kaesemeyer, WH1
Prisant, LM1
Carr, AA1
Thulin, T1
de la Figuera von Wichmann, M1
Scholz, G1
Marek, H1
Kellner, K1
Husum, D1
Johnsen, A1
Jensen, G1
Brouwer, RM1
Follath, F1
Bühler, FR1
Brill, DM1
Berman, BA1
Ross, RN1
Palombo, C1
Mian, M1
Bertelli, A1
Lehtonen, LA1
Eskola, JT1
Gordin, A1
Erkko, MK1
Räihä, IJ1
Lehtonen, AA1
Strauss, WE1
Parisi, AF1
De Gregorio, G1
Restivo, S1
De Gregorio, C1
Burgess, CD1
Larach, DR1
Zelis, R1
Winniford, MD1
Hillis, LD1
Bezer, G1
Duchêne-Marullaz, P1
Lavarenne, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
INternational VErapamil SR Trandolapril STudy[NCT00133692]Phase 422,000 participants Interventional1997-09-30Completed
Qianyangyuyin Formula Prevent and Treat for Early Renal Injury in Hypertensive Patients[NCT04078711]Phase 2/Phase 3520 participants (Anticipated)Interventional2019-09-10Not yet recruiting
A Two-Phase Study for Primary and Secondary Prevention of Diabetic Nephropathy by Combined ACE Inhibition and Calcium Channel Blockade (BENEDICT)[NCT00235014]Phase 41,204 participants (Actual)Interventional1997-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

21 reviews available for verapamil and Cardiovascular Diseases

ArticleYear
Treatments for diabetes mellitus type II: New perspectives regarding the possible role of calcium and cAMP interaction.
    European journal of pharmacology, 2018, Jul-05, Volume: 830

    Topics: Adjuvants, Pharmaceutic; Animals; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Cyclic

2018
[Use of Verapamil and Dilthiasem in treating patients at high cardiovascular risk (review of literature)].
    Meditsina truda i promyshlennaia ekologiia, 2016, Issue:2

    Topics: Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Humans; Verapamil

2016
Clinical applications of slow channel blocking compounds.
    Pharmacology & therapeutics, 1983, Volume: 23, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Platelets; Blood Vessels; Calcium

1983
[Side-effects of calcium antagonists].
    La Clinica terapeutica, 1984, Jun-30, Volume: 109, Issue:6

    Topics: Calcium Channel Blockers; Cardiovascular Diseases; Drug Hypersensitivity; Drug Interactions; Fendili

1984
Calcium channel blocking agents in the treatment of cardiovascular disorders. Part I: Basic and clinical electrophysiologic effects.
    Annals of internal medicine, 1980, Volume: 93, Issue:6

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel B

1980
History of calcium antagonists.
    Circulation research, 1983, Volume: 52, Issue:2 Pt 2

    Topics: Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Gallopamil;

1983
Calcium channel blocking agents in the treatment of cardiovascular disorders. Part II: Hemodynamic effects and clinical applications.
    Annals of internal medicine, 1980, Volume: 93, Issue:6

    Topics: Benzazepines; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Circulation; Diltiazem; He

1980
Role of calcium antagonists in cardiovascular therapy.
    British heart journal, 1981, Volume: 46, Issue:1

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Blood Vessels; Calcium; Calcium Channel Blockers; Cardiomyopa

1981
Re-examining the clinical safety and roles of calcium antagonists in cardiovascular medicine.
    The American journal of cardiology, 1996, Nov-07, Volume: 78, Issue:9A

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiovascular Diseases; Cor

1996
Calcium antagonists and cardiovascular prognosis: a homogeneous group?
    American journal of hypertension, 1996, Volume: 9, Issue:2

    Topics: Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Dihydropyridines; Dilti

1996
Verapamil use in patients with cardiovascular disease: an overview of randomized trials.
    Clinical cardiology, 1998, Volume: 21, Issue:9

    Topics: Angina Pectoris; Calcium Channel Blockers; Cardiovascular Diseases; Female; Humans; Hypertension; Ma

1998
Calcium-channel blockers and gingival hyperplasia.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:2

    Topics: Aged; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Female; Gingival Hyperplasia; Hu

1992
Calcium antagonists--assessment of side effects.
    Scandinavian journal of primary health care. Supplement, 1990, Volume: 1

    Topics: Benzodiazepines; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Health Status;

1990
[Verapamil: a primary care antihypertensive].
    Atencion primaria, 1990, Volume: 7, Issue:1

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Primary Health Care; Risk Fa

1990
Review of the cardiovascular adversity of the calcium antagonist beta-blocker combination: implications for antihypertensive therapy.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 4

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Drug Ther

1985
Treating coexisting cardiovascular and pulmonary disease with calcium antagonists.
    Annals of allergy, 1986, Volume: 56, Issue:3

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Asthma, Exercise-Induced; Bronchial Spasm; Calcium; Ca

1986
[Calcium antagonists: accounts on new perspectives of their use and an update on side effects].
    La Clinica terapeutica, 1989, Feb-15, Volume: 128, Issue:3

    Topics: Adult; Animals; Asthma; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Esophageal Ach

1989
Combined use of calcium-channel and beta-adrenergic blockers for the treatment of chronic stable angina. Rationale, efficacy, and adverse effects.
    Annals of internal medicine, 1988, Oct-01, Volume: 109, Issue:7

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Diseases; Dil

1988
Advances in calcium blocker therapy.
    American journal of surgery, 1986, Volume: 151, Issue:4

    Topics: Arrhythmias, Cardiac; Arteriosclerosis; Asthma; Blood Platelet Disorders; Calcium; Calcium Channel B

1986
Calcium antagonists in patients with cardiovascular disease. Current perspectives.
    Medicine, 1985, Volume: 64, Issue:1

    Topics: Angina Pectoris; Angina Pectoris, Variant; Atrial Fibrillation; Atrial Flutter; Benzazepines; Cardio

1985
[Recent data on coronary dilators].
    Actualites pharmacologiques, 1968, Volume: 21

    Topics: Amino Alcohols; Aminophylline; Animals; Benzofurans; Cardiovascular Diseases; Cats; Coronary Disease

1968

Trials

9 trials available for verapamil and Cardiovascular Diseases

ArticleYear
Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:1

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Cardiovasc

2013
Effects of verapamil added-on trandolapril therapy in hypertensive type 2 diabetes patients with microalbuminuria: the BENEDICT-B randomized trial.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channe

2011
Effects of verapamil added-on trandolapril therapy in hypertensive type 2 diabetes patients with microalbuminuria: the BENEDICT-B randomized trial.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channe

2011
Effects of verapamil added-on trandolapril therapy in hypertensive type 2 diabetes patients with microalbuminuria: the BENEDICT-B randomized trial.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channe

2011
Effects of verapamil added-on trandolapril therapy in hypertensive type 2 diabetes patients with microalbuminuria: the BENEDICT-B randomized trial.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channe

2011
Measurable urinary albumin predicts cardiovascular risk among normoalbuminuric patients with type 2 diabetes.
    Journal of the American Society of Nephrology : JASN, 2012, Volume: 23, Issue:10

    Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Cardiotonic Agents; Cardiov

2012
Prognostic implications of renal dysfunction in patients with stable angina pectoris.
    Journal of internal medicine, 2006, Volume: 260, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Disease

2006
Blood pressure control and improved cardiovascular outcomes in the International Verapamil SR-Trandolapril Study.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:2

    Topics: Aged; Blood Pressure Determination; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug

2007
Calcium channel blocking agents in the treatment of cardiovascular disorders. Part I: Basic and clinical electrophysiologic effects.
    Annals of internal medicine, 1980, Volume: 93, Issue:6

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel B

1980
Rationale and design for the Controlled ONset Verapamil INvestigation of Cardiovascular Endpoints (CONVINCE) Trial.
    Controlled clinical trials, 1998, Volume: 19, Issue:4

    Topics: Aged; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Cerebrovascular Disorders; Double-

1998
Inflammatory and hemostatic markers in relation to cardiovascular prognosis in patients with stable angina pectoris. Results from the APSIS study. The Angina Prognosis Study in Stockholm.
    Atherosclerosis, 2000, Volume: 148, Issue:1

    Topics: Adrenergic beta-Agonists; Aged; Angina Pectoris; beta-Thromboglobulin; Calcium Channel Blockers; Car

2000
[Cerebrovascular effects of verapamil and prevention of headache. Clinico-experimental control].
    La Clinica terapeutica, 1987, Apr-15, Volume: 121, Issue:1

    Topics: Adult; Blood Pressure; Cardiovascular Diseases; Cerebrovascular Circulation; Clinical Trials as Topi

1987

Other Studies

44 other studies available for verapamil and Cardiovascular Diseases

ArticleYear
Analytical techniques for the determination of verapamil in biological samples and dosage forms: an overview.
    Bioanalysis, 2019, Volume: 11, Issue:23

    Topics: Administration, Oral; Breath Tests; Calcium Channel Blockers; Cardiovascular Diseases; Drug Industry

2019
Novel nonsynonymous variants associated with blood pressure control in response to antihypertensives and their impact on cardiovascular outcomes.
    Pharmacogenomics, 2013, Volume: 14, Issue:15

    Topics: Cardiovascular Diseases; Factor V; Female; Glycoproteins; Humans; Immunoglobulins; Indoles; Lectins;

2013
CACNA1C gene polymorphisms, cardiovascular disease outcomes, and treatment response.
    Circulation. Cardiovascular genetics, 2009, Volume: 2, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atenolol; Calcium Channel Blockers; Calcium Channel

2009
[Seizure and non-cardiogenic pulmonary edema after intoxication].
    Der Internist, 2010, Volume: 51, Issue:4

    Topics: Adult; Cardiovascular Diseases; Diagnosis, Differential; Female; Humans; Pulmonary Edema; Seizures;

2010
Use of clopidogrel and calcium channel blockers and risk of major adverse cardiovascular events.
    European journal of clinical investigation, 2012, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angioplasty, Balloon, Coronary; Calcium Chan

2012
Termination of refractory focal status epilepticus by the P-glycoprotein inhibitor verapamil.
    European journal of neurology, 2011, Volume: 18, Issue:12

    Topics: Aged, 80 and over; Anticonvulsants; Aspirin; ATP Binding Cassette Transporter, Subfamily B, Member 1

2011
Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Adult; Alleles; Atenolol; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol,

2012
Ethnic, racial, and sex-specific factors are important in cardiovascular pharmacotherapeutics.
    Archives of internal medicine, 2002, Nov-25, Volume: 162, Issue:21

    Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Black People; Cardiovascular Agents; Cardiovascular

2002
Verapamil is associated with an increased risk of cancer in the elderly: the Rotterdam study.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:1

    Topics: Aged; Calcium Channel Blockers; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Fe

2003
Adult hypertension: reducing cardiovascular morbidity and mortality.
    Prescrire international, 2005, Volume: 14, Issue:75

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking

2005
The impact of diabetes or elevated fasting blood glucose on cardiovascular prognosis in patients with stable angina pectoris.
    Diabetic medicine : a journal of the British Diabetic Association, 2005, Volume: 22, Issue:10

    Topics: Angina Pectoris; Anti-Arrhythmia Agents; Blood Glucose; Cardiovascular Diseases; Diabetic Angiopathi

2005
Inhibition of rat platelet aggregation by Urtica dioica leaves extracts.
    Phytotherapy research : PTR, 2006, Volume: 20, Issue:7

    Topics: Animals; Aspirin; Cardiovascular Diseases; Female; Male; Mice; Phytotherapy; Plant Extracts; Plant L

2006
Hypertension treatment: how important is consistency of effect?
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:2

    Topics: Antihypertensive Agents; Atenolol; Blood Pressure Determination; Cardiovascular Diseases; Cohort Stu

2007
Pharmacological basis for the use of Borago officinalis in gastrointestinal, respiratory and cardiovascular disorders.
    Journal of ethnopharmacology, 2007, Dec-03, Volume: 114, Issue:3

    Topics: Animals; Aorta; Borago; Calcium; Cardiovascular Diseases; Dose-Response Relationship, Drug; Female;

2007
Welcome--the calcium channel blockers.
    Chest, 1981, Volume: 80, Issue:6

    Topics: Adrenergic beta-Antagonists; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium Channel Blocker

1981
Therapeutic implications of slow-channel blockade in cardiocirculatory disorders.
    Circulation, 1980, Volume: 62, Issue:4

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium; Cardiovascular Diseases; Coronary Disease; Diltiazem

1980
Calcium channel blockers for cardiovascular disorders.
    Archives of internal medicine, 1982, Volume: 142, Issue:3

    Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers;

1982
Antidotal treatment of the acute cardiovascular toxicity of verapamil.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:3

    Topics: Animals; Antidotes; Blood Pressure; Cardiac Output; Cardiovascular Diseases; Electrocardiography; He

1984
Calcium channel blockers. New treatment for cardiovascular disease.
    The American journal of nursing, 1983, Volume: 83, Issue:3

    Topics: Adult; Angina Pectoris; Calcium; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Cardiovascu

1983
Calcium channel blockers: verapamil and nifedipine.
    Critical care update, 1983, Volume: 10, Issue:9

    Topics: Calcium; Cardiovascular Diseases; Humans; Nifedipine; Verapamil

1983
Pharmacology and electrophysiology of calcium ion antagonists.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1980, Volume: 3, Issue:1-2

    Topics: Calcium; Cardiovascular Diseases; Gallopamil; Heart; Humans; Myocardial Contraction; Nitroglycerin;

1980
Calcium blocker therapy in cardiovascular disease.
    Journal of the South Carolina Medical Association (1975), 1982, Volume: 78, Issue:7

    Topics: Adult; Aged; Calcium Channel Blockers; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; N

1982
Calcium channel blockers: indications and limitations 1. Clinical pharmacology and use as antiarrhythmic agents.
    Postgraduate medicine, 1982, Volume: 72, Issue:5

    Topics: Anti-Arrhythmia Agents; Biological Availability; Calcium; Calcium Channel Blockers; Cardiovascular D

1982
The current status of calcium antagonists in cardiovascular therapy.
    Singapore medical journal, 1982, Volume: 23, Issue:2

    Topics: Calcium Channel Blockers; Cardiovascular Diseases; Humans; Nifedipine; Verapamil

1982
Therapeutic uses of calcium-blocking agents:verapamil, nifedipine, and diltiazem.
    Comprehensive therapy, 1981, Volume: 7, Issue:10

    Topics: Benzazepines; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Humans; Nifedipine; Pyri

1981
Verapamil.
    The Journal of the Kansas Medical Society, 1981, Volume: 82, Issue:10

    Topics: Cardiovascular Diseases; Humans; Verapamil

1981
[Calcium inhibitors. Current indications in cardiology].
    La Revue du praticien, 1980, Feb-01, Volume: 30, Issue:7

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium; Cardiovascular Diseases; Diltiazem; Humans; Nifedipi

1980
Insulin is a superior antidote for cardiovascular toxicity induced by verapamil in the anesthetized canine.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Anesthesia; Animals; Antidotes; Blood Glucose; Cardiovascular Diseases; Disease Models, Animal; Dogs

1993
Calcium channel antagonists. What do the second-generation agents have to offer?
    Postgraduate medicine, 1994, Volume: 95, Issue:1

    Topics: Arteriosclerosis; Calcium Channel Blockers; Cardiovascular Diseases; Cerebrovascular Disorders; Dihy

1994
The use of calcium channel blockers in general practice.
    Australian family physician, 1993, Volume: 22, Issue:3

    Topics: Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Diltiazem; Family Practice; Fem

1993
Vascular calcium overload produced by vitamin D3, in rats. Effect of treatment with SR 33805, a novel calcium entry blocker.
    Cardiovascular research, 1995, Volume: 30, Issue:6

    Topics: Animals; Aorta, Thoracic; Calcinosis; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Ch

1995
Revisiting calcium channel blockers--from basic facts to clinical practice.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1996, Volume: 86 Suppl 3

    Topics: Aged; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Nifedipine

1996
The effects of amrinone and glucagon on verapamil-induced cardiovascular toxicity in anaesthetized rats.
    International journal of experimental pathology, 1996, Volume: 77, Issue:5

    Topics: Amrinone; Animals; Blood Pressure; Bradycardia; Calcium Channel Blockers; Cardiovascular Diseases; D

1996
Timing treatment to the rhythm of disease. A short course in chronotherapeutics.
    Postgraduate medicine, 2001, Volume: 110, Issue:2

    Topics: Antineoplastic Agents; Asthma; Cardiovascular Diseases; Chronotherapy; Circadian Rhythm; Humans; Hyd

2001
[Value of verapamil in long-term treatment of coronary disease, hypertension and functional disorders of the cardiovascular system].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1979, Oct-01, Volume: 32, Issue:19

    Topics: Adult; Cardiovascular Diseases; Coronary Disease; Female; Humans; Hypertension; Male; Middle Aged; V

1979
Verapamil and nifedipine in combination for the treatment of hypertrophy heart disease.
    American journal of hypertension, 1991, Volume: 4, Issue:10 Pt 1

    Topics: Adrenal Gland Diseases; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Humans;

1991
[The effect of verapamil on adrenocortical hormone secretion].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1990, Jul-01, Volume: 45, Issue:13

    Topics: Adrenocorticotropic Hormone; Adult; Cardiovascular Diseases; Circadian Rhythm; Dose-Response Relatio

1990
Requirements for drug monitoring of verapamil: experience from an unselected group of patients with cardiovascular disease.
    Pharmacology & toxicology, 1990, Volume: 66, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Biotransformation; Cardiovascular Diseases; Chromatography, High Pre

1990
Calcium channel blocking drugs. Part II: Clinical applications.
    Comprehensive therapy, 1985, Volume: 11, Issue:10

    Topics: Angina Pectoris; Angina Pectoris, Variant; Angina, Unstable; Arrhythmias, Cardiac; Calcium Channel B

1985
The effect of calcium channel blocking on immune capacity of cardiovascular patients.
    Journal of clinical & laboratory immunology, 1989, Volume: 30, Issue:2

    Topics: Adult; Aged; Calcium Channel Blockers; Cardiovascular Diseases; Female; Humans; Immunoglobulins; Imm

1989
Univer, a new one-daily calcium antagonist--its role in cardiovascular disease. Proceedings of a symposium. London, 9th October 1987.
    British journal of clinical practice. Supplement, 1988, Volume: 60

    Topics: Cardiovascular Diseases; Humans; Verapamil

1988
Calcium channel antagonists--cardiovascular therapy for the eighties?
    The New Zealand medical journal, 1986, May-28, Volume: 99, Issue:802

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem;

1986
Dantrolene sodium intravenous--verapamil.
    Anaesthesia and intensive care, 1985, Volume: 13, Issue:1

    Topics: Animals; Cardiovascular Diseases; Dantrolene; Drug Interactions; Swine; Verapamil

1985
Verapamil in cardiology.
    European journal of cardiology, 1974, Volume: 2, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Anura; Arrhythmi

1974