Page last updated: 2024-10-24

verapamil and Cardiomyopathy, Congestive

verapamil has been researched along with Cardiomyopathy, Congestive in 28 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"Hemodynamic effects of the beta-receptor-blocking agent metoprolol (100 mg orally) and the calcium antagonist verapamil (160 mg orally) were analyzed in 24 patients with atrial fibrillation of different etiology (idiopathic atrial fibrillation, 6 cases; congestive cardiomyopathy, 6 cases; mitral stenosis, 5 cases; mitral regurgitation, 6 cases)."9.05[Modification of hemodynamics in tachycardiac atrial fibrillation by metoprolol and verapamil]. ( Bilgin, Y; Gigler, G; Maier, WD; Neuss, H; Schlepper, M; Thormann, J, 1983)
"The effects of the calcium channel blocking agent, verapamil, were studied in a murine model of viral myocarditis."7.68Verapamil ameliorates the clinical and pathological course of murine myocarditis. ( Butany, J; Dong, R; Liu, P; Sole, MJ; Wee, L, 1992)
"In a patient with WPW syndrome and idiopathic dilated cardiomyopathy, intractable atrioventricular reentrant tachycardia (AVRT) was iatrogenically induced."5.30Iatrogenically induced intractable atrioventricular reentrant tachycardia after verapamil and catheter ablation in a patient with Wolff-Parkinson-White syndrome and idiopathic dilated cardiomyopathy. ( Aihara, N; Kamakura, S; Kurita, T; Nakayama, Y; Shimomura, K, 1997)
"Hemodynamic effects of the beta-receptor-blocking agent metoprolol (100 mg orally) and the calcium antagonist verapamil (160 mg orally) were analyzed in 24 patients with atrial fibrillation of different etiology (idiopathic atrial fibrillation, 6 cases; congestive cardiomyopathy, 6 cases; mitral stenosis, 5 cases; mitral regurgitation, 6 cases)."5.05[Modification of hemodynamics in tachycardiac atrial fibrillation by metoprolol and verapamil]. ( Bilgin, Y; Gigler, G; Maier, WD; Neuss, H; Schlepper, M; Thormann, J, 1983)
"The effects of the calcium channel blocking agent, verapamil, were studied in a murine model of viral myocarditis."3.68Verapamil ameliorates the clinical and pathological course of murine myocarditis. ( Butany, J; Dong, R; Liu, P; Sole, MJ; Wee, L, 1992)
"At present, the therapies of dilated cardiomyopathy concentrated on the symptoms of heart failure and related complications."3.01Comparative Efficacy of Different Drugs for the Treatment of Dilated Cardiomyopathy: A Systematic Review and Network Meta-analysis. ( Chang, S; Lu, S; Shen, L; Tong, X; Wang, Y; Zhou, X, 2023)
" Incidents of adverse cardiac drug reactions are more common in patients with preexisting heart disease than the general population."1.39Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. ( Bers, DM; Diecke, S; Gong, T; Knowles, JW; Lan, F; Lee, AS; Liang, P; Nguyen, PK; Robbins, RC; Sallam, K; Sanchez-Freire, V; Wang, PJ; Wang, Y; Wu, JC, 2013)
"These findings, consistent with a dilated cardiomyopathy, were ameliorated in the early but not in the late treatment group, demonstrating that late treatment with verapamil is ineffective in reversing the development of chagasic cardiomyopathy in chronically infected mice."1.32Effects of early and late verapamil administration on the development of cardiomyopathy in experimental chronic Trypanosoma cruzi (Brazil strain) infection. ( Chandra, M; De Souza, AP; Factor, SM; Huang, H; Jelicks, LA; Morris, SA; Shirani, J; Shtutin, V; Tanowitz, HB; Weiss, LM; Wittner, M, 2004)
"In a patient with WPW syndrome and idiopathic dilated cardiomyopathy, intractable atrioventricular reentrant tachycardia (AVRT) was iatrogenically induced."1.30Iatrogenically induced intractable atrioventricular reentrant tachycardia after verapamil and catheter ablation in a patient with Wolff-Parkinson-White syndrome and idiopathic dilated cardiomyopathy. ( Aihara, N; Kamakura, S; Kurita, T; Nakayama, Y; Shimomura, K, 1997)
"Twenty-five VTs showed right bundle branch block morphology and 23 left bundle branch block morphology, and VT was entrained in 84 and 96%, respectively."1.29Frequency of presumed reentry with an excitable gap in sustained ventricular tachycardia unassociated with coronary artery disease. ( Aizawa, Y; Kitazawa, H; Kusano, Y; Naitoh, N; Shibata, A; Uchiyama, H; Washizuka, T, 1993)
"The case of a patient with idiopathic dilated cardiomyopathy and complex ventricular arrhythmias who underwent placement of an automatic implantable cardioverter-defibrillator (AICD) and experienced inappropriate shocks during atrial fibrillation is presented."1.28Emergency department management of patients with automatic implantable cardioverter-defibrillators. ( Craig, SA; Hudson, AD, 1990)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199011 (39.29)18.7374
1990's11 (39.29)18.2507
2000's2 (7.14)29.6817
2010's3 (10.71)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Tong, X1
Shen, L2
Zhou, X1
Wang, Y2
Chang, S1
Lu, S1
Liang, P1
Lan, F1
Lee, AS1
Gong, T1
Sanchez-Freire, V1
Diecke, S1
Sallam, K1
Knowles, JW1
Wang, PJ1
Nguyen, PK1
Bers, DM1
Robbins, RC1
Wu, JC1
Wyles, SP1
Hrstka, SC1
Reyes, S1
Terzic, A1
Olson, TM1
Nelson, TJ1
Wojnicz, R1
Nowak, J1
Lekston, A1
Wilczewski, P1
Nowalany-Kozielska, E1
Streb, W1
Wojciechowska, C1
Stolarz, W1
Helewski, K1
Szyguła-Jurkiewicz, B1
Poloński, L1
De Souza, AP1
Tanowitz, HB1
Chandra, M1
Shtutin, V1
Weiss, LM1
Morris, SA1
Factor, SM1
Huang, H1
Wittner, M1
Shirani, J1
Jelicks, LA1
Maier, WD1
Neuss, H1
Bilgin, Y1
Gigler, G1
Thormann, J1
Schlepper, M1
Piovan, D1
Padrini, R1
Svalato Moreolo, G1
Magnolfi, G1
Milanesi, O1
Zordan, R1
Pellegrino, PA1
Ferrari, M1
Brown, RA1
Bhasin, P1
Savage, AO1
Dunbar, JC1
Aizawa, Y1
Naitoh, N1
Kitazawa, H1
Kusano, Y1
Uchiyama, H1
Washizuka, T1
Shibata, A1
Finkel, MS1
Oddis, CV1
Romeo, RC1
Nakayama, Y1
Kurita, T1
Aihara, N1
Kamakura, S1
Shimomura, K1
Wakabayashi, Y1
Kurata, C1
Mikami, T1
Shouda, S1
Okayama, K1
Tawarahara, K1
Neglia, D1
Sambuceti, G1
Giorgetti, A1
Bartoli, M1
Salvadori, P1
Sorace, O1
Puccini, G1
L'Abbate, A1
Parodi, O1
Dong, R1
Liu, P1
Wee, L1
Butany, J1
Sole, MJ1
Toshima, H1
Takabatake, Y1
Denisiuk, VI1
Belokonnaia, NS1
Craig, SA1
Hudson, AD1
Whelton, PK1
Watson, AJ1
Kone, B1
Fortuin, NJ1
Matsumori, A1
Tominaga, M1
Kawai, C1
Belli, B1
Michelucci, A1
Monizzi, D1
Barletta, G1
Morace, G2
Padeletti, L1
Barbieri, L1
Mestroni, L1
Camerini, F1
Richardson, PJ1
Baughman, KL1
Rao, PS1
Najjar, HN1
Manfroi, WC2
Ludwig, RT2
Vieira, SR2
Goldim, JR2
Das, SK2
de Freitas, FM2
Faraco, EZ2
Figulla, HR1
Kreuzer, H1
Luig, H1

Reviews

4 reviews available for verapamil and Cardiomyopathy, Congestive

ArticleYear
Comparative Efficacy of Different Drugs for the Treatment of Dilated Cardiomyopathy: A Systematic Review and Network Meta-analysis.
    Drugs in R&D, 2023, Volume: 23, Issue:3

    Topics: Cardiomyopathy, Dilated; Carvedilol; Humans; Ivabradine; Network Meta-Analysis; Randomized Controlle

2023
[Calcium antagonists in congestive heart failure].
    Giornale italiano di cardiologia, 1988, Volume: 18, Issue:11

    Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Diltiazem; Felodipine; Heart Failure; Hemodynamic

1988
Calcium antagonists in cardiomyopathy.
    British journal of clinical practice. Supplement, 1988, Volume: 60

    Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Humans; Verapamil

1988
Calcium channel blocking agents in congestive heart failure.
    The American journal of medicine, 1986, Feb-28, Volume: 80, Issue:2B

    Topics: Administration, Oral; Biological Transport; Calcium; Calcium Channel Blockers; Cardiac Output; Cardi

1986

Trials

7 trials available for verapamil and Cardiomyopathy, Congestive

ArticleYear
Therapeutic window for calcium-channel blockers in the management of dilated cardiomyopathy: a prospective, two-centre study on non-advanced disease.
    Cardiology, 2010, Volume: 117, Issue:2

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Calcium Channel Blockers; Carb

2010
[Modification of hemodynamics in tachycardiac atrial fibrillation by metoprolol and verapamil].
    Zeitschrift fur Kardiologie, 1983, Volume: 72, Issue:8

    Topics: Atrial Fibrillation; Cardiac Output; Cardiomyopathy, Dilated; Heart Rate; Hemodynamics; Humans; Meto

1983
Verapamil and norverapamil plasma levels in infants and children during chronic oral treatment.
    Therapeutic drug monitoring, 1995, Volume: 17, Issue:1

    Topics: Administration, Oral; Adolescent; Aging; Cardiomyopathy, Dilated; Child; Child, Preschool; Female; H

1995
Effects of long-term treatment with verapamil on left ventricular function and myocardial blood flow in patients with dilated cardiomyopathy without overt heart failure.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:6

    Topics: Calcium Channel Blockers; Cardiac Output; Cardiomyopathy, Dilated; Coronary Circulation; Double-Blin

2000
[Effect of the optimal dose of finoptin on various components of the circulatory system in heart failure in patients with ischemic heart disease].
    Kardiologiia, 1990, Volume: 30, Issue:7

    Topics: Administration, Sublingual; Adult; Aged; Cardiomyopathy, Dilated; Coronary Disease; Dose-Response Re

1990
[Acute hemodynamic effect of verapamil, used intravenously, in patients with primary dilated cardiomyopathy].
    Arquivos brasileiros de cardiologia, 1985, Volume: 45, Issue:5

    Topics: Cardiomyopathy, Dilated; Clinical Trials as Topic; Depression, Chemical; Female; Hemodynamics; Human

1985
[Verapamil, diltiazem or nifedipine in severe left ventricular functional disorder? A comparative study of the immediate hemodynamic effects].
    Deutsche medizinische Wochenschrift (1946), 1986, Jan-03, Volume: 111, Issue:1

    Topics: Adult; Calcium Channel Blockers; Cardiac Volume; Cardiomyopathy, Dilated; Diltiazem; Female; Heart R

1986

Other Studies

17 other studies available for verapamil and Cardiomyopathy, Congestive

ArticleYear
Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
    Circulation, 2013, Apr-23, Volume: 127, Issue:16

    Topics: Action Potentials; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic, Familial; Cell Differentia

2013
Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient-Derived iPSC Model.
    Clinical and translational science, 2016, Volume: 9, Issue:3

    Topics: Apoptosis; Calcium; Calcium Signaling; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Homeostasis;

2016
Effects of early and late verapamil administration on the development of cardiomyopathy in experimental chronic Trypanosoma cruzi (Brazil strain) infection.
    Parasitology research, 2004, Volume: 92, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Chagas Cardiomyopathy; Chagas Disease; Dis

2004
Chronic verapamil treatment attenuates the negative inotropic effect of ethanol in diabetic rat myocardium.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:9

    Topics: Animals; Cardiomyopathy, Dilated; Diabetes Mellitus, Experimental; Drug Interactions; Ethanol; Male;

1994
Frequency of presumed reentry with an excitable gap in sustained ventricular tachycardia unassociated with coronary artery disease.
    The American journal of cardiology, 1993, Oct-15, Volume: 72, Issue:12

    Topics: Adolescent; Adult; Bundle of His; Bundle-Branch Block; Cardiac Pacing, Artificial; Cardiomyopathy, D

1993
Verapamil regulation of a defective SR release channel in the cardiomyopathic Syrian hamster.
    Life sciences, 1993, Volume: 52, Issue:13

    Topics: Animals; Calcium; Calcium Channels; Cardiomyopathy, Dilated; Cardiotonic Agents; Cricetinae; Disease

1993
Iatrogenically induced intractable atrioventricular reentrant tachycardia after verapamil and catheter ablation in a patient with Wolff-Parkinson-White syndrome and idiopathic dilated cardiomyopathy.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:7

    Topics: Adult; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Catheter Ablation; Electrocardiography; Huma

1997
Effects of cilazapril and verapamil on myocardial iodine-125-metaiodobenzylguanidine accumulation in cardiomyopathic BIO 53.58 hamsters.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:10

    Topics: 3-Iodobenzylguanidine; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers;

1997
Verapamil ameliorates the clinical and pathological course of murine myocarditis.
    The Journal of clinical investigation, 1992, Volume: 90, Issue:5

    Topics: Animals; Cardiomyopathy, Dilated; Encephalomyocarditis virus; Enterovirus Infections; Male; Mice; Mi

1992
[Progress in the treatment of myocardial diseases].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1990, Mar-10, Volume: 79, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiomyopathy, Di

1990
[Calcium antagonists in cardiomyopathy].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:1

    Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Coronary Circulatio

1991
Emergency department management of patients with automatic implantable cardioverter-defibrillators.
    Annals of emergency medicine, 1990, Volume: 19, Issue:4

    Topics: Atrial Fibrillation; Cardiomyopathy, Dilated; Electric Countershock; Electrocardiography; Emergencie

1990
Calcium channel blockade in dialysis patients with left ventricular hypertrophy and well-preserved systolic function.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Aged; Blood Pressure; Body Weight; Cardiomegaly; Cardiomyopathy, Dilated; Echocardiography; Female;

1987
[Treatment of cardiomyopathy using Ca blockers].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 47, Issue:8

    Topics: Animals; Calcium Channel Blockers; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Cricetinae

1989
Reversible cardiomyopathy following chronic supraventricular tachycardia.
    Cardiologia (Rome, Italy), 1988, Volume: 33, Issue:7

    Topics: Adult; Cardiomyopathy, Dilated; Chronic Disease; Digoxin; Drug Combinations; Electrocardiography; Hu

1988
Congestive cardiomyopathy due to chronic tachycardia: resolution of cardiomyopathy with antiarrhythmic drugs.
    International journal of cardiology, 1987, Volume: 17, Issue:2

    Topics: Cardiomyopathy, Dilated; Child, Preschool; Digoxin; Drug Therapy, Combination; Electrocardiography;

1987
[Effect of the chronic use of verapamil, by oral route, in patients with primary dilated cardiomyopathy: a new therapeutic approach?].
    Arquivos brasileiros de cardiologia, 1985, Volume: 45, Issue:4

    Topics: Administration, Oral; Cardiomyopathy, Dilated; Female; Follow-Up Studies; Hemodynamics; Humans; Male

1985