verapamil has been researched along with Cardiomyopathy, Chagas in 7 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In previous work, we have shown that the chronic administration of verapamil, a calcium channel blocker, ameliorated the mortality, pathology, and biochemical alterations associated with acute murine Chagas' disease." | 5.28 | Effect of verapamil on the development of chronic experimental Chagas' disease. ( Bilezikian, JP; Factor, SM; Morris, SA; Tanowitz, HB; Weiss, LM; Wittner, M, 1989) |
| "These findings, consistent with a dilated cardiomyopathy, were ameliorated in the early but not in the late treatment group, demonstrating that late treatment with verapamil is ineffective in reversing the development of chagasic cardiomyopathy in chronically infected mice." | 1.32 | Effects of early and late verapamil administration on the development of cardiomyopathy in experimental chronic Trypanosoma cruzi (Brazil strain) infection. ( Chandra, M; De Souza, AP; Factor, SM; Huang, H; Jelicks, LA; Morris, SA; Shirani, J; Shtutin, V; Tanowitz, HB; Weiss, LM; Wittner, M, 2004) |
| "In previous work, we have shown that the chronic administration of verapamil, a calcium channel blocker, ameliorated the mortality, pathology, and biochemical alterations associated with acute murine Chagas' disease." | 1.28 | Effect of verapamil on the development of chronic experimental Chagas' disease. ( Bilezikian, JP; Factor, SM; Morris, SA; Tanowitz, HB; Weiss, LM; Wittner, M, 1989) |
| "Amiodarone was the only one of the four drugs that caused a substantial reduction of ventricular premature complexes (logarithmic mean 97." | 1.27 | Comparative antiarrhythmic efficacy of verapamil, 17-monochloracetylajmaline, mexiletine and amiodarone in patients with severe chagasic myocarditis: relation with the underlying arrhythmogenic mechanisms. ( Bandieri, JD; Chiale, PA; Elizari, MV; Haedo, AH; Lázzari, JO; Rosenbaum, MB, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Souza, AP | 1 |
| Tanowitz, HB | 4 |
| Chandra, M | 2 |
| Shtutin, V | 1 |
| Weiss, LM | 5 |
| Morris, SA | 4 |
| Factor, SM | 3 |
| Huang, H | 3 |
| Wittner, M | 5 |
| Shirani, J | 2 |
| Jelicks, LA | 2 |
| Sterin-Borda, L | 1 |
| Canga, L | 1 |
| Cossio, PM | 1 |
| Diez, C | 1 |
| Arana, RM | 1 |
| Gimeno, AL | 1 |
| Zhao, W | 1 |
| Hatcher, VB | 1 |
| Braunstein, VL | 2 |
| Douglas, SA | 1 |
| Valcic, M | 1 |
| Spektor, M | 1 |
| Christ, GJ | 1 |
| Bekirov, I | 1 |
| Chan, J | 1 |
| Bilezikian, JP | 2 |
| Factor, S | 1 |
| Tanowitz, H | 1 |
| Haedo, AH | 1 |
| Chiale, PA | 1 |
| Bandieri, JD | 1 |
| Lázzari, JO | 1 |
| Elizari, MV | 1 |
| Rosenbaum, MB | 1 |
7 other studies available for verapamil and Cardiomyopathy, Chagas
| Article | Year |
|---|---|
Effects of early and late verapamil administration on the development of cardiomyopathy in experimental chronic Trypanosoma cruzi (Brazil strain) infection.
Topics: Animals; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Chagas Cardiomyopathy; Chagas Disease; Dis | 2004 |
Calcium ions and the influence of chagasic sera on the effects of ouabain on isolated rat atria.
Topics: Animals; Antibodies; Calcium; Chagas Cardiomyopathy; Heart Atria; Humans; In Vitro Techniques; Male; | 1981 |
The putative mechanistic basis for the modulatory role of endothelin-1 in the altered vascular tone induced by Trypanosoma cruzi.
Topics: Animals; Aorta; Calcium; Cells, Cultured; Chagas Cardiomyopathy; Endothelin Receptor Antagonists; En | 1999 |
Application of cardiac gated magnetic resonance imaging in murine Chagas' disease.
Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Cardiomyopathies; Chagas Cardiomyopathy; En | 1999 |
Effect of verapamil on the development of chronic experimental Chagas' disease.
Topics: Adenylyl Cyclases; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Models, | 1989 |
Verapamil ameliorates clinical, pathologic and biochemical manifestations of experimental chagasic cardiomyopathy in mice.
Topics: Adenylyl Cyclases; Animals; Chagas Cardiomyopathy; Male; Mice; Trypanosoma cruzi; Verapamil | 1989 |
Comparative antiarrhythmic efficacy of verapamil, 17-monochloracetylajmaline, mexiletine and amiodarone in patients with severe chagasic myocarditis: relation with the underlying arrhythmogenic mechanisms.
Topics: Adult; Ajmaline; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Chagas Cardiomyopathy; Female; Human | 1986 |