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verapamil and Cardiomyopathy, Chagas

verapamil has been researched along with Cardiomyopathy, Chagas in 7 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"In previous work, we have shown that the chronic administration of verapamil, a calcium channel blocker, ameliorated the mortality, pathology, and biochemical alterations associated with acute murine Chagas' disease."5.28Effect of verapamil on the development of chronic experimental Chagas' disease. ( Bilezikian, JP; Factor, SM; Morris, SA; Tanowitz, HB; Weiss, LM; Wittner, M, 1989)
"These findings, consistent with a dilated cardiomyopathy, were ameliorated in the early but not in the late treatment group, demonstrating that late treatment with verapamil is ineffective in reversing the development of chagasic cardiomyopathy in chronically infected mice."1.32Effects of early and late verapamil administration on the development of cardiomyopathy in experimental chronic Trypanosoma cruzi (Brazil strain) infection. ( Chandra, M; De Souza, AP; Factor, SM; Huang, H; Jelicks, LA; Morris, SA; Shirani, J; Shtutin, V; Tanowitz, HB; Weiss, LM; Wittner, M, 2004)
"In previous work, we have shown that the chronic administration of verapamil, a calcium channel blocker, ameliorated the mortality, pathology, and biochemical alterations associated with acute murine Chagas' disease."1.28Effect of verapamil on the development of chronic experimental Chagas' disease. ( Bilezikian, JP; Factor, SM; Morris, SA; Tanowitz, HB; Weiss, LM; Wittner, M, 1989)
"Amiodarone was the only one of the four drugs that caused a substantial reduction of ventricular premature complexes (logarithmic mean 97."1.27Comparative antiarrhythmic efficacy of verapamil, 17-monochloracetylajmaline, mexiletine and amiodarone in patients with severe chagasic myocarditis: relation with the underlying arrhythmogenic mechanisms. ( Bandieri, JD; Chiale, PA; Elizari, MV; Haedo, AH; Lázzari, JO; Rosenbaum, MB, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Souza, AP1
Tanowitz, HB4
Chandra, M2
Shtutin, V1
Weiss, LM5
Morris, SA4
Factor, SM3
Huang, H3
Wittner, M5
Shirani, J2
Jelicks, LA2
Sterin-Borda, L1
Canga, L1
Cossio, PM1
Diez, C1
Arana, RM1
Gimeno, AL1
Zhao, W1
Hatcher, VB1
Braunstein, VL2
Douglas, SA1
Valcic, M1
Spektor, M1
Christ, GJ1
Bekirov, I1
Chan, J1
Bilezikian, JP2
Factor, S1
Tanowitz, H1
Haedo, AH1
Chiale, PA1
Bandieri, JD1
Lázzari, JO1
Elizari, MV1
Rosenbaum, MB1

Other Studies

7 other studies available for verapamil and Cardiomyopathy, Chagas

ArticleYear
Effects of early and late verapamil administration on the development of cardiomyopathy in experimental chronic Trypanosoma cruzi (Brazil strain) infection.
    Parasitology research, 2004, Volume: 92, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Chagas Cardiomyopathy; Chagas Disease; Dis

2004
Calcium ions and the influence of chagasic sera on the effects of ouabain on isolated rat atria.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 250, Issue:1

    Topics: Animals; Antibodies; Calcium; Chagas Cardiomyopathy; Heart Atria; Humans; In Vitro Techniques; Male;

1981
The putative mechanistic basis for the modulatory role of endothelin-1 in the altered vascular tone induced by Trypanosoma cruzi.
    Endothelium : journal of endothelial cell research, 1999, Volume: 6, Issue:3

    Topics: Animals; Aorta; Calcium; Cells, Cultured; Chagas Cardiomyopathy; Endothelin Receptor Antagonists; En

1999
Application of cardiac gated magnetic resonance imaging in murine Chagas' disease.
    The American journal of tropical medicine and hygiene, 1999, Volume: 61, Issue:2

    Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Cardiomyopathies; Chagas Cardiomyopathy; En

1999
Effect of verapamil on the development of chronic experimental Chagas' disease.
    The American journal of tropical medicine and hygiene, 1989, Volume: 41, Issue:6

    Topics: Adenylyl Cyclases; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Models,

1989
Verapamil ameliorates clinical, pathologic and biochemical manifestations of experimental chagasic cardiomyopathy in mice.
    Journal of the American College of Cardiology, 1989, Volume: 14, Issue:3

    Topics: Adenylyl Cyclases; Animals; Chagas Cardiomyopathy; Male; Mice; Trypanosoma cruzi; Verapamil

1989
Comparative antiarrhythmic efficacy of verapamil, 17-monochloracetylajmaline, mexiletine and amiodarone in patients with severe chagasic myocarditis: relation with the underlying arrhythmogenic mechanisms.
    Journal of the American College of Cardiology, 1986, Volume: 7, Issue:5

    Topics: Adult; Ajmaline; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Chagas Cardiomyopathy; Female; Human

1986