verapamil has been researched along with Cardiac Diseases in 80 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether gallopamil (D600), a methoxy derivative of verapamil, administered immediately before coronary artery reperfusion reduces the extent of myocardial hemorrhage and necrosis, the left anterior descending coronary artery was occluded for 3 h and reperfused for 3 h in anesthetized, open-chest dogs." | 7.68 | Reduction in myocardial hemorrhage and the extent of necrosis by gallopamil (D600) in dogs with coronary artery reperfusion. ( Endo, T; Hayakawa, H; Maroko, PR; Sato, N, 1991) |
| " In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular toxicity of seven known human cardiotoxic drugs (aspirin, clomipramine hydrochloride, cyclophosphamide, nimodipine, quinidine, terfenadine and verapamil hydrochloride) and two non-cardiovascular toxicity drugs (gentamicin sulphate and tetracycline hydrochloride) in zebrafish using six specific phenotypic endpoints: heart rate, heart rhythm, pericardial edema, circulation, hemorrhage and thrombosis." | 3.80 | Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish. ( Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ, 2014) |
| "To determine whether gallopamil (D600), a methoxy derivative of verapamil, administered immediately before coronary artery reperfusion reduces the extent of myocardial hemorrhage and necrosis, the left anterior descending coronary artery was occluded for 3 h and reperfused for 3 h in anesthetized, open-chest dogs." | 3.68 | Reduction in myocardial hemorrhage and the extent of necrosis by gallopamil (D600) in dogs with coronary artery reperfusion. ( Endo, T; Hayakawa, H; Maroko, PR; Sato, N, 1991) |
| "To determine whether verapamil, diltiazem, or nifedipine affect digitoxin kinetics, glycoside plasma concentrations and renal excretion were measured before and during steady-state dosing in 30 patients with cardiac insufficiency." | 2.66 | Effects of verapamil, diltiazem, and nifedipine on plasma levels and renal excretion of digitoxin. ( Kuhlmann, J, 1985) |
| "Nifedipine generally has little depressant action in this setting and usually improves cardiac function, especially if the sympathetic reflexes are intact." | 2.37 | Use of calcium antagonists in ventricular dysfunction. ( Josephson, MA; Singh, BN, 1985) |
| " The study reported here was designed to show whether the pharmacokinetics of verapamil are influenced by concurrent treatment with three different beta-adrenoceptor blockers, and whether there is any pharmacodynamic interaction between these drugs." | 1.27 | Pharmacokinetics and pharmacodynamics of verapamil in combination with atenolol, metoprolol and propranolol. ( Fitzsimons, TJ; Holt, D; Johnston, A; Warrington, SJ, 1984) |
| "Verapamil-treated hamsters received intraperitoneal injections of verapamil at a dose of 5 mg/kg per day for 70 days from age 20 days." | 1.27 | Effects of verapamil on experimental cardiomyopathy in the Bio 14.6 Syrian hamster. ( Hayashi, H; Kaneko, M; Kobayashi, A; Nishiyama, T; Yamashita, T; Yamazaki, N, 1987) |
| "Eight patients with refractory ovarian cancer were treated on a pilot protocol of verapamil plus Adriamycin (Adria Laboratories, Columbus, OH)." | 1.27 | Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients. ( Cunnion, RE; Hamilton, TC; Klecker, RW; Ostchega, Y; Ozols, RF; Parrillo, JE; Young, RC, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (77.50) | 18.7374 |
| 1990's | 10 (12.50) | 18.2507 |
| 2000's | 5 (6.25) | 29.6817 |
| 2010's | 2 (2.50) | 24.3611 |
| 2020's | 1 (1.25) | 2.80 |
| Authors | Studies |
|---|---|
| Bardien-Kruger, S | 1 |
| Wulff, H | 1 |
| Arieff, Z | 1 |
| Brink, P | 1 |
| Chandy, KG | 1 |
| Corfield, V | 1 |
| Jolobe, OMP | 1 |
| Mazur, NA | 1 |
| Khezheva, FM | 1 |
| Kasprzak, JD | 1 |
| Stępińska, J | 1 |
| Wożakowska Kapłon, B | 1 |
| Drożdż, J | 1 |
| Grajek, S | 1 |
| Opolski, G | 1 |
| Rynkiewicz, A | 1 |
| Tykarski, A | 1 |
| Filipiak, KJ | 1 |
| Zhu, JJ | 1 |
| Xu, YQ | 1 |
| He, JH | 1 |
| Yu, HP | 1 |
| Huang, CJ | 1 |
| Gao, JM | 1 |
| Dong, QX | 1 |
| Xuan, YX | 1 |
| Li, CQ | 1 |
| Burnett, JW | 1 |
| Calton, GJ | 1 |
| Opie, LH | 1 |
| Giorgetti, C | 1 |
| Danisi, M | 1 |
| Viti, V | 1 |
| Barsotti, GP | 1 |
| Pratali, MC | 1 |
| Lander, R | 1 |
| Warrington, SJ | 1 |
| Holt, D | 1 |
| Johnston, A | 1 |
| Fitzsimons, TJ | 1 |
| Wolff, F | 1 |
| Breuker, KH | 1 |
| Schlensker, KH | 1 |
| Bolte, A | 1 |
| Tullio, D | 1 |
| Valerio, A | 1 |
| D'Agostino, F | 1 |
| Young, GP | 1 |
| Ebner, F | 1 |
| Donath, M | 1 |
| Rämsch, KD | 1 |
| Fazekas, T | 1 |
| Rabkin, SW | 1 |
| Otten, M | 1 |
| Polimeni, PI | 1 |
| Bonow, RO | 1 |
| Zelis, RF | 1 |
| Dipalma, JR | 1 |
| King, BD | 1 |
| Pitchon, R | 1 |
| Stern, EH | 1 |
| Schweitzer, P | 1 |
| Schneider, RR | 1 |
| Weiner, I | 1 |
| Merola, P | 1 |
| Badin, A | 1 |
| Paleari, DC | 1 |
| De Petris, A | 1 |
| Maragno, I | 1 |
| Keefe, DL | 1 |
| Yee, YG | 1 |
| Kates, RE | 1 |
| Check, WA | 1 |
| Ruedy, J | 1 |
| Resnekov, L | 1 |
| Pozenel, H | 1 |
| Woodcock, BG | 1 |
| Schulz, W | 1 |
| Kober, G | 1 |
| Rietbrock, N | 1 |
| Rodrigues, B | 1 |
| Grassby, PF | 1 |
| Battell, ML | 1 |
| Lee, SY | 1 |
| McNeill, JH | 1 |
| Madsen, JK | 1 |
| Hansen, JF | 1 |
| Fan, J | 1 |
| Zhang, Y | 1 |
| Zhang, M | 1 |
| Conlin, PR | 1 |
| Williams, GH | 1 |
| Volkov, AM | 1 |
| Kazanskaya, GM | 1 |
| Chasovskikh, GG | 1 |
| D'yakonitsa, TM | 1 |
| Zhdanov, GP | 1 |
| Lomivorotov, VN | 1 |
| Sah, R | 1 |
| Oudit, GY | 1 |
| Nguyen, TT | 1 |
| Lim, HW | 1 |
| Wickenden, AD | 1 |
| Wilson, GJ | 1 |
| Molkentin, JD | 1 |
| Backx, PH | 1 |
| Singh, BN | 2 |
| Roche, AH | 1 |
| Stefan, G | 1 |
| Willstein, A | 1 |
| Breinl, H | 1 |
| Meinen, K | 1 |
| Schmidt, EW | 1 |
| Ripa, R | 2 |
| Ledda, F | 1 |
| Strano, A | 1 |
| Amino, JG | 1 |
| Studart, PC | 2 |
| de Brito, AH | 1 |
| Brando, PR | 1 |
| Maia, IG | 2 |
| Almeida, G | 1 |
| Dohmann, HJ | 1 |
| Moll, JN | 1 |
| Romão, R | 1 |
| Santos, MA | 1 |
| Drumond Neto, C | 1 |
| Dohmann, H | 1 |
| Reis, NB | 1 |
| Hordof, AJ | 1 |
| Edie, R | 1 |
| Malm, JR | 1 |
| Hoffman, BF | 1 |
| Rosen, MR | 1 |
| Zehender, M | 1 |
| Hohnloser, S | 1 |
| Müller, B | 1 |
| Meinertz, T | 1 |
| Just, H | 1 |
| Schwinger, RH | 2 |
| Böhm, M | 2 |
| Erdmann, E | 2 |
| Endo, T | 1 |
| Sato, N | 1 |
| Hayakawa, H | 1 |
| Maroko, PR | 1 |
| Cohen, A | 1 |
| Weizman, A | 1 |
| Eldar, M | 1 |
| Rehavi, M | 1 |
| Morishita, Y | 1 |
| Toyohira, H | 1 |
| Yamashita, M | 1 |
| Shimokawa, S | 1 |
| Umebayashi, Y | 1 |
| Saigenji, H | 1 |
| Hashiguchi, M | 1 |
| Kawashima, S | 1 |
| Moriyama, Y | 1 |
| Taira, A | 1 |
| Mazurek, W | 1 |
| Halawa, B | 1 |
| Kobayashi, A | 1 |
| Yamashita, T | 1 |
| Kaneko, M | 1 |
| Nishiyama, T | 1 |
| Hayashi, H | 1 |
| Yamazaki, N | 1 |
| Palócz, E | 1 |
| Buday, G | 1 |
| Kerkovits, G | 1 |
| Broustet, JP | 1 |
| Mora, B | 1 |
| Douard, H | 1 |
| Muiesan, G | 1 |
| Zimmer, HG | 1 |
| Zierhut, W | 1 |
| Marschner, G | 1 |
| Kingma, JG | 1 |
| Yellon, DM | 1 |
| Ozols, RF | 1 |
| Cunnion, RE | 1 |
| Klecker, RW | 1 |
| Hamilton, TC | 1 |
| Ostchega, Y | 1 |
| Parrillo, JE | 1 |
| Young, RC | 1 |
| Garrett, JS | 1 |
| Wikman-Coffelt, J | 1 |
| Sievers, R | 1 |
| Finkbeiner, WE | 1 |
| Parmley, WW | 1 |
| Gordon, M | 1 |
| Goldenberg, LM | 1 |
| Josephson, MA | 1 |
| Kuhlmann, J | 2 |
| Kenny, J | 1 |
| Marcin, S | 1 |
| Leder, O | 2 |
| Hardewig, A | 1 |
| Andresen, T | 1 |
| Thormann, J | 1 |
| Bleifeld, W | 1 |
| Merx, W | 1 |
| Effert, S | 1 |
| Adjan, M | 1 |
| Rudolph, W | 4 |
| Kriener, J | 4 |
| Meister, W | 4 |
| Yokoyama, H | 1 |
| Manns, KJ | 1 |
| Döring, HJ | 1 |
| Reindell, A | 1 |
| Fleckenstein, A | 1 |
| De Liperi, E | 1 |
| Coli, R | 1 |
| Brunori, F | 1 |
| Singer, MT | 1 |
| Schmitt, G | 1 |
| Eisel, K | 1 |
| Kaiser, H | 1 |
| de Abrantes, IB | 1 |
| Villela, RA | 1 |
| Faillace, S | 1 |
| Villela, AA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000542] | Phase 3 | 0 participants | Interventional | 1993-08-31 | Completed | ||
| Comparism Between Efficacy and Effectiveness Between Slow Infusion of Calcium Channel Blockers and Intravenous Bolus Adenosine in the Management of Supraventricular Tachycardia in the Emergency Department.[NCT00413712] | Phase 4 | 206 participants | Interventional | 1997-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for verapamil and Cardiac Diseases
| Article | Year |
|---|---|
Verapamil/beta-blocker interaction. A review.
Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Atrial Flutter; Calcium; Drug Interactions; | 1983 |
[Calcium antagonists in cardiology].
Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Disease; Dilt | 1983 |
Calcium channel blockers in emergency medicine.
Topics: Action Potentials; Animals; Benzazepines; Calcium; Diltiazem; Emergencies; Heart Diseases; Humans; N | 1984 |
Clinical differentiation of nifedipine and other calcium antagonists.
Topics: Biological Availability; Calcium Channel Blockers; Diltiazem; Drug Tolerance; Heart Diseases; Hemody | 1984 |
Verapamil.
Topics: Action Potentials; Angina Pectoris; Animals; Calcium; Cardiovascular System; Heart Diseases; Hemodyn | 1981 |
Use of calcium channel blockers in hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Case-Control Stud | 1998 |
[Calcium antagonists in arterial hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Drug Interactions; Heart Diseases; Hemodynamics; Humans; Hypert | 1988 |
Use of calcium antagonists in ventricular dysfunction.
Topics: Calcium Channel Blockers; Diltiazem; Heart Diseases; Heart Ventricles; Hemodynamics; Humans; Hyperte | 1985 |
Calcium channel blocking agents and the heart.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Vasospasm; Digoxin; Diltia | 1985 |
8 trials available for verapamil and Cardiac Diseases
| Article | Year |
|---|---|
Calcium antagonists: long-awaited new therapy for heart disease.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Benzazepines; Calcium; Cardiomyopathies; Clinical Trials as T | 1981 |
Hemodynamic effects of calcium antagonists in cardiac patients.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Cardiac Catheterization; Dose-Response Relationship, | 1982 |
Mortality of patients excluded from the Danish Verapamil Infarction Trail II. The DAVIT-II Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium Channel Blockers; Clinical Protocols; Clinical Tri | 1993 |
Effects of intravenous verapamil on hemodynamics in patients with heart disease.
Topics: Adult; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Coronary Disease; Depression, Chemi | 1977 |
Effects of amiodarone versus quinidine and verapamil in patients with chronic atrial fibrillation: results of a comparative study and a 2-year follow-up.
Topics: Amiodarone; Atrial Fibrillation; Chronic Disease; Drug Therapy, Combination; Electrocardiography; Fe | 1992 |
[Verapamil in combination therapy].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Digita | 1985 |
Effects of verapamil, diltiazem, and nifedipine on plasma levels and renal excretion of digitoxin.
Topics: Aged; Benzazepines; Clinical Trials as Topic; Digitoxin; Diltiazem; Drug Interactions; Drug Therapy, | 1985 |
[Influencing the cardiotonic effect of proscillaridin by verapamil].
Topics: Anti-Arrhythmia Agents; Blood Pressure Determination; Cardiac Glycosides; Cardiac Output; Drug Syner | 1969 |
63 other studies available for verapamil and Cardiac Diseases
| Article | Year |
|---|---|
Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI).
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; COS Cells; DNA; Heart Block; Heart | 2002 |
Cardiac and extracardiac side effects of eye drops.
Topics: Adrenergic beta-Antagonists; Atropine; Bradycardia; Carteolol; Female; Heart Diseases; Humans; Ophth | 2021 |
[Effect of hypotensive therapy on metalloproteinase activity of the blood in patients with arterial hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Enz | 2009 |
[Optimum heart rate - the current goal of cardiovascular therapy. Position statement of the Polish Cardiac Society Working Group on Cardiovascular Drug Therapy].
Topics: Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Di | 2012 |
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease | 2014 |
The case for verapamil use in alarming jellyfish stings remains.
Topics: Animals; Antivenins; Bites and Stings; Cnidarian Venoms; Cubozoa; Heart Diseases; Verapamil | 2004 |
Drugs and the heart. III. Calcium antagonists.
Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Di | 1980 |
[Prospects for drug therapy in the rehabilitation of the cardiac patient].
Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Benzofurans; Heart Diseases; Humans; Male; Middle Ag | 1980 |
Pharmacokinetics and pharmacodynamics of verapamil in combination with atenolol, metoprolol and propranolol.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Drug Interactions; Female; Half-Life; | 1984 |
Prenatal diagnosis and therapy of fetal heart rate anomalies: with a contribution on the placental transfer of Verapamil.
Topics: Adult; Bradycardia; Cardiac Complexes, Premature; Electrocardiography; Female; Fetal Diseases; Fetal | 1980 |
Mechanism of action and clinical use of Ca++-antagonists.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Electrophysiology; Heart Diseases; Humans; Mu | 1983 |
Increased mortality with cardiotoxic doses of Adriamycin after verapamil pretreatment despite prevention of myocardial calcium accumulation.
Topics: Animals; Body Water; Calcium; Doxorubicin; Electroencephalography; Electrolytes; Extracellular Space | 1983 |
Noninvasive evaluation of left ventricular diastolic function by radionuclide angiography: limitations and applications.
Topics: Diastole; Heart; Heart Diseases; Heart Ventricles; Humans; Myocardial Contraction; Radionuclide Imag | 1984 |
Calcium antagonists and the heart.
Topics: Calcium; Heart Diseases; Humans; Nifedipine; Verapamil | 1981 |
Calcium entry blockers in cardiologic therapy.
Topics: Angina Pectoris, Variant; Calcium; Cardiovascular Agents; Diltiazem; Heart Diseases; Hemodynamics; H | 1981 |
Calcium channel blockers.
Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem | 1983 |
Impotence during therapy with verapamil.
Topics: Adult; Aged; Digoxin; Drug Therapy, Combination; Erectile Dysfunction; Heart Diseases; Humans; Male; | 1983 |
[Influence of verapamil on the plasma level of digoxin in man].
Topics: Adult; Digoxin; Drug Interactions; Heart Diseases; Humans; Middle Aged; Verapamil | 1982 |
Calcium antagonists in cardiovascular therapy. Proceedings of the Second International Verapamil Symposium in Australia. Melbourne, November 1981.
Topics: Calcium Channel Blockers; Heart Diseases; Humans; Verapamil | 1982 |
Verapamil protein binding in patients and in normal subjects.
Topics: Adult; Aged; Animals; Blood Proteins; Cardiac Catheterization; Coronary Artery Bypass; Dogs; Heart D | 1981 |
Calcium ion blocking drugs.
Topics: Administration, Oral; Bradycardia; Calcium Channel Blockers; Diltiazem; Dizziness; Headache; Heart D | 1982 |
Direct determination of hepatic extraction of verapamil in cardiac patients.
Topics: Adult; Aorta; Cardiac Catheterization; Female; Heart Diseases; Hepatic Veins; Humans; Injections, In | 1981 |
Hypertriglyceridemia in experimental diabetes: relationship to cardiac dysfunction.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Cholesterol; Clofibrate; Diabetes Mellitus, Experim | 1994 |
[Effects of verapamil on left ventricular diastolic dysfunction].
Topics: Adolescent; Adult; Aged; Calcium Channel Blockers; Cardiac Catheterization; Cardiomyopathy, Hypertro | 1995 |
Effect of calcium antagonists on ultrastructure of myocardial microvessels during open heart surgery under conditions of pharmacological and cold cardioplegia.
Topics: Body Temperature; Calcium; Cardiac Surgical Procedures; Child; Cold Temperature; Heart; Heart Arrest | 2001 |
Inhibition of calcineurin and sarcolemmal Ca2+ influx protects cardiac morphology and ventricular function in K(v)4.2N transgenic mice.
Topics: Action Potentials; Animals; Biological Transport; Calcineurin Inhibitors; Calcium; Calcium Channel B | 2002 |
[Echocardiography during the therapy of cardiovascular diseases].
Topics: Calcium Chloride; Digoxin; Echocardiography; Heart Diseases; Heart Ventricles; Humans; Isoproterenol | 1977 |
[The possibility of heart-muscle damage through fenoterol (elektrocardiographic and blood-chemistry studies with particular reference to the heart-muscle-specific isoenzym creatinkinase MB.) (author's transl)].
Topics: Adult; Creatine Kinase; Drug Synergism; Electrocardiography; Ethanolamines; Female; Fenoterol; Heart | 1977 |
[Calcium antagonists in cardiologic therapy].
Topics: Calcium; Coronary Disease; Heart Diseases; Humans; Nifedipine; Pyridines; Sodium; Verapamil | 1978 |
[Calcium antagonists in cardiologic therapy].
Topics: Calcium; Coronary Disease; Heart Diseases; Humans; Myocardium; Nifedipine; Pyridines; Verapamil | 1978 |
[Pharmacological assumptions in the use of calcium antagonists].
Topics: Arrhythmias, Cardiac; Calcium; Coronary Disease; Heart Diseases; Humans; Nifedipine; Pyridines; Vera | 1978 |
[Calcium antagonists in cardiology. Introduction].
Topics: Calcium; Coronary Circulation; Heart Diseases; Humans; Myocardium; Nifedipine; Verapamil | 1978 |
[Action of verapamil on the dynamics of heart conduction].
Topics: Adolescent; Adult; Child; Drug Evaluation; Female; Heart Conduction System; Heart Defects, Congenita | 1977 |
Action of verapamil on the sinus node recovery time and AV conduction studied by His bundle recordings.
Topics: Adolescent; Adult; Bundle of His; Coronary Disease; Electrocardiography; Heart Diseases; Heart Rate; | 1977 |
Electrophysiologic properties and response to pharmacologic agents of fibers from diseased human atria.
Topics: Action Potentials; Adolescent; Child; Child, Preschool; Electrocardiography; Electrophysiology; Hear | 1976 |
Negative inotropic properties of isradipine, nifedipine, diltiazem, and verapamil in diseased human myocardial tissue.
Topics: Adult; Aged; Calcium Channel Blockers; Calcium Chloride; Diltiazem; Electric Stimulation; Female; He | 1990 |
Reduction in myocardial hemorrhage and the extent of necrosis by gallopamil (D600) in dogs with coronary artery reperfusion.
Topics: Animals; Autoradiography; Blood Pressure; Coronary Vessels; Dogs; Female; Gallopamil; Heart Diseases | 1991 |
Negative inotropic activity of the calcium antagonists isradipine, nifedipine, diltiazem, and verapamil in diseased human myocardium.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Dose-Response Re | 1991 |
Long-term verapamil treatment increases [3H]imipramine binding in human platelets.
Topics: Blood Platelets; Carrier Proteins; Cell Membrane; Female; Heart Diseases; Humans; Imipramine; Male; | 1990 |
[The optional usage of blood cardioplegia through eleven-year experience of open-heart surgery].
Topics: Adult; Aged; Blood; Female; Heart Arrest, Induced; Heart Diseases; Humans; Male; Middle Aged; Verapa | 1990 |
[Interactions between quinidine and verapamil].
Topics: Adult; Drug Interactions; Half-Life; Heart Diseases; Humans; Male; Middle Aged; Quinidine; Verapamil | 1989 |
Effects of verapamil on experimental cardiomyopathy in the Bio 14.6 Syrian hamster.
Topics: Age Factors; Animals; Calcium; Cricetinae; Free Radicals; Heart; Heart Diseases; Lipid Peroxides; Me | 1987 |
Use of drugs in cardiac rehabilitation.
Topics: Adrenergic beta-Antagonists; Amiodarone; Diltiazem; Drug Therapy, Combination; Electrocardiography; | 1986 |
Combination of ribose with calcium antagonist and beta-blocker treatment in closed-chest rats.
Topics: Adenine Nucleotides; Animals; Cardiac Output; Disease Models, Animal; Dose-Response Relationship, Dr | 1987 |
Limitation of myocardial necrosis with verapamil during sustained coronary occlusion in the closed-chest dog.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Heart Diseases; Male; Necrosis; Verapamil | 1988 |
Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Doxorubicin; Drug Resistance; Female | 1987 |
Verapamil prevents the development of alcoholic dysfunction in hamster myocardium.
Topics: Animals; Cricetinae; Ethanol; Heart Diseases; Hemodynamics; Mesocricetus; Verapamil | 1987 |
Clinical digoxin toxicity in the aged in association with co-administered verapamil. A report of two cases and review of the literature.
Topics: Aged; Digoxin; Drug Interactions; Female; Heart Diseases; Humans; Kinetics; Quinidine; Verapamil | 1986 |
Effects of verapamil on pharmacokinetics and pharmacodynamics of digitoxin in patients.
Topics: Aged; Arrhythmias, Cardiac; Digitoxin; Drug Therapy, Combination; Electrocardiography; Heart Disease | 1985 |
Proceedings: Changes in myocardial ultrastructure and autoradiographic 45Ca distribution during isoproterenol-induced cardiac necrotization--prevention by Ca-antagonistic compounds.
Topics: Adrenal Cortex Hormones; Animals; Autoradiography; Calcium; Calcium Radioisotopes; Dihydrotachystero | 1974 |
[What is certain in the therapy of heart diseases?].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Output; Digitalis | 1969 |
[Clinical pharmacology and adverse effects of various anti-arrhythmic drugs].
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Bone Marrow Diseases; Central Nervous Sys | 1971 |
[Gradulon and gradulon s. T. in the treatment of heart diseases of various causes in the daily practice].
Topics: Arrhythmias, Cardiac; Benzoates; Coronary Disease; Digoxin; Drug Combinations; Heart Diseases; Heart | 1972 |
[Effect of verapamil on coronary blood flow, oxygen utilisation and carbon dioxide production in human heart].
Topics: Carbon Dioxide; Coronary Vessels; Electrocardiography; Heart; Heart Defects, Congenital; Heart Disea | 1971 |
[Substrate metabolism of the human heart under the influence of iproveratril (Verapamil)].
Topics: Acetoacetates; Anti-Arrhythmia Agents; Fatty Acids, Nonesterified; Heart Diseases; Humans; Hydroxybu | 1971 |
[Oxygen uptake and carbon dioxide release by the human heart under the influence of iproveratril (Verapamil)].
Topics: Anti-Arrhythmia Agents; Carbon Dioxide; Cardiac Catheterization; Heart; Heart Diseases; Humans; Myoc | 1971 |
[The influence of orally applied iproveratril (Verapamil) on coronayy blood flow, oxygen consumption and carbon dioxide formation in the human heart].
Topics: Anti-Arrhythmia Agents; Blood Pressure; Carbon Dioxide; Coronary Vessels; Heart; Heart Diseases; Hum | 1971 |
[Clinical physiopathological studies on myocardial oxygen metabolism. 3. Myocardial oxygen metabolism during administration of coronary dilators].
Topics: Adolescent; Adult; Aged; Benzoates; Benzofurans; Coronary Disease; Coumarins; Dipyridamole; Female; | 1971 |
[Protective effect of organic Ca antagonists (iproveratril, D 600, prenylamine) against isoproterenol-induced myocardial necrosis].
Topics: Animals; Anti-Arrhythmia Agents; Calcium; Heart; Heart Diseases; Isoproterenol; Necrosis; Nitriles; | 1969 |
[Clinical trials of the effect of verapamil in subjects with angina pectoris].
Topics: Adult; Aged; Angina Pectoris; Anti-Arrhythmia Agents; Arteriosclerosis; Coronary Disease; Female; He | 1970 |
[On the protective effect of iproveratil in myocardial diseases due to hypertension in animal experiment].
Topics: Animals; Anti-Arrhythmia Agents; Electrocardiography; Heart Diseases; Hypertension, Renal; Hypoxia; | 1967 |
[On the clinical trial of a heart and coronary drug].
Topics: Adult; Aged; Cardiac Glycosides; Coronary Disease; Heart Diseases; Heart Failure; Humans; Middle Age | 1968 |
[Clinical evaluation of iproveratril].
Topics: Adult; Angina Pectoris; Anti-Arrhythmia Agents; Electrocardiography; Female; Heart Diseases; Humans; | 1968 |