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verapamil and Cancer of Rectum

verapamil has been researched along with Cancer of Rectum in 5 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"The potential for a pharmacokinetic interaction between epirubicin and the second-generation multidrug resistance modulating agent D-verapamil (DVPM) has been investigated in six patients with advanced colorectal cancer."1.29Pharmacokinetic interaction between epirubicin and the multidrug resistance reverting agent D-verapamil. ( Czejka, M; Scheithauer, W; Schenk, T, 1993)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scheithauer, W1
Schenk, T1
Czejka, M1
Matsumoto, J2
Minami, T2
Sato, T2
Onodera, T2
Kramer, RA1
Zakher, J1
Kim, G1
Ince, P1
Appleton, DR1
Finney, KJ1
Sunter, JP1
Watson, AJ1

Other Studies

5 other studies available for verapamil and Cancer of Rectum

ArticleYear
Pharmacokinetic interaction between epirubicin and the multidrug resistance reverting agent D-verapamil.
    British journal of cancer, 1993, Volume: 68, Issue:1

    Topics: Colonic Neoplasms; Drug Resistance; Epirubicin; Female; Half-Life; Humans; Male; Metabolic Clearance

1993
[Hepatic arterial infusion chemotherapy combined with calcium antagonist for liver metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:11

    Topics: Adult; Aged; Colonic Neoplasms; Doxorubicin; Female; Humans; Infusion Pumps, Implantable; Infusions,

1993
[A clinical trial of arterial infusion chemotherapy combined with calcium antagonist for liver metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Doxorubicin; Drug Synergism; Drug Therapy,

1992
Role of the glutathione redox cycle in acquired and de novo multidrug resistance.
    Science (New York, N.Y.), 1988, Aug-05, Volume: 241, Issue:4866

    Topics: Animals; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Resistance; Glutathione; Glutathione Perox

1988
Verapamil increases the sensitivity of primary human colorectal carcinoma tissue to vincristine.
    British journal of cancer, 1986, Volume: 53, Issue:1

    Topics: Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Humans; In Vit

1986