verapamil has been researched along with Cancer of Eye in 3 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The chemosensitizing effects of cyclosporin A and verapamil on the cytotoxicity of adriamycin were investigated using MTT assay against two human retinoblastoma cell lines, Y79 and WERI-Rb-1." | 7.68 | Chemosensitization to adriamycin by cyclosporin A and verapamil in human retinoblastoma cell lines. ( Hong, WS; Kim, CM; Lee, TW; Yang, SW; Youn, DH, 1993) |
| "The chemosensitizing effects of cyclosporin A and verapamil on the cytotoxicity of adriamycin were investigated using MTT assay against two human retinoblastoma cell lines, Y79 and WERI-Rb-1." | 3.68 | Chemosensitization to adriamycin by cyclosporin A and verapamil in human retinoblastoma cell lines. ( Hong, WS; Kim, CM; Lee, TW; Yang, SW; Youn, DH, 1993) |
| " Dose-response studies indicated that exceedingly high doses of DTIC were necessary to produce antimetastatic effects even when drug treatment was combined with the calcium channel blocker verapamil." | 1.28 | Efficacy of dacarbazine (DTIC) in preventing metastases arising from intraocular melanomas in mice. ( Gamel, JW; Niederkorn, JY; Sanborn, GE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abruzzo, TA | 1 |
| Geller, JI | 1 |
| Kimbrough, DA | 1 |
| Michaels, S | 1 |
| Corrêa, ZM | 1 |
| Cornell, K | 1 |
| Augsburger, JJ | 1 |
| Lee, TW | 1 |
| Yang, SW | 1 |
| Kim, CM | 1 |
| Hong, WS | 1 |
| Youn, DH | 1 |
| Sanborn, GE | 1 |
| Niederkorn, JY | 1 |
| Gamel, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Intra-Ophthalmic Artery Topotecan Infusion for the Treatment of Retinoblastoma[NCT01466855] | Early Phase 1 | 36 participants (Actual) | Interventional | 2011-10-31 | Terminated (stopped due to Competing studies) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for verapamil and Cancer of Eye
| Article | Year |
|---|---|
Adjunctive techniques for optimization of ocular hemodynamics in children undergoing ophthalmic artery infusion chemotherapy.
Topics: Adolescent; Antineoplastic Agents; Balloon Occlusion; Carotid Artery, External; Carotid Artery, Inte | 2015 |
2 other studies available for verapamil and Cancer of Eye
| Article | Year |
|---|---|
Chemosensitization to adriamycin by cyclosporin A and verapamil in human retinoblastoma cell lines.
Topics: Cell Survival; Cyclosporine; Doxorubicin; Eye Neoplasms; Humans; Retinoblastoma; Tumor Cells, Cultur | 1993 |
Efficacy of dacarbazine (DTIC) in preventing metastases arising from intraocular melanomas in mice.
Topics: Animals; Anterior Eye Segment; Dacarbazine; Eye Enucleation; Eye Neoplasms; Female; Lung Neoplasms; | 1992 |