Page last updated: 2024-10-24

verapamil and Burns

verapamil has been researched along with Burns in 11 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"TAC may be beneficial for the short-term treatment of hypertrophic scars and keloids; however, 5-FU, 5-FU+TAC, and verapamil may produce superior results for medium- and long-term treatments."9.12The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021)
"TAC may be beneficial for the short-term treatment of hypertrophic scars and keloids; however, 5-FU, 5-FU+TAC, and verapamil may produce superior results for medium- and long-term treatments."5.12The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021)
" Spinal pretreatment with cyclooxygenase (10 and 30 microg (S)-(+)-ibuprofen; and 3 and 30 microg ketorolac) and nitric oxide synthase (33 and 100 microg N(G) Nitro-L-arginine methyl ester hydrochloride (L-NAME) and 10 microg thiocitrulline) inhibitors resulted in no specific anti-allodynia."3.74Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase. ( Doom, CM; Maruyama, KP; Nanigian, DB; Sorkin, LS, 2008)
"The formation of hypertrophic scaring (HSc) is an abnormal wound-healing response."1.46A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study. ( Chuang, SS; Hsiao, YC; Yang, JY; Yang, SY, 2017)
" Combination therapy can reduce the dosage of each drug but achieve equal or better efficacy than monotherapy, reducing the side effects of a single drug."1.36The effect of combined steroid and calcium channel blocker injection on human hypertrophic scars in animal model: a new strategy for the treatment of hypertrophic scars. ( Huang, CY; Yang, JY, 2010)
"Pretreatment with ritanserin, BW A1433U83, atropine, ICI 118551, diphenhydramine, ranitidine, meclofenamate, L-nitro-arginine methyl ester, 3-amino-1,2,4-triazine, and U 37883A had no effect on the increased femoral blood flow response to scald, suggesting this vasodilator response is not dependent upon activation of serotonergic2, adenosineA1, muscarinic, beta 2-adrenergic, histaminergic1 or histaminergic2 receptors, on cyclooxygenase products, endothelium-derived relaxing factor derived from nitric oxide (NO) synthase III, NO derived from NO synthase II, or KATP channels, respectively."1.29Analysis of regional hemodynamic regulation in response to scald injury. ( Ferrara, JJ; Flint, LM; Force, SD; Franklin, EW; Hyman, AL; Lippton, HL; Taheri, PA, 1994)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Ahuja, RB1
Chatterjee, P1
Wang, P1
Gu, L1
Bi, H1
Qin, Z1
Zhuang, Z1
Li, Y1
Wei, X1
Yang, SY1
Yang, JY2
Hsiao, YC1
Chuang, SS1
Huang, CY1
Sorkin, LS1
Doom, CM1
Maruyama, KP1
Nanigian, DB1
Hilton, JG2
Lee, RC1
Doong, H1
Jellema, AF1
Taheri, PA1
Lippton, HL1
Force, SD1
Franklin, EW1
Hyman, AL1
Flint, LM1
Ferrara, JJ1
Shen, H1
Chen, Y1
Liu, S1
Marullo, DS1

Reviews

1 review available for verapamil and Burns

ArticleYear
The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
    Burns : journal of the International Society for Burn Injuries, 2021, Volume: 47, Issue:5

    Topics: Atrophy; Burns; Cicatrix, Hypertrophic; Culture Media; Fluorouracil; Humans; Injections, Intralesion

2021

Other Studies

10 other studies available for verapamil and Burns

ArticleYear
Response to Letter to the Editor: Comments on "Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids".
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:7

    Topics: Burns; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; V

2020
Comments on "Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids".
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:7

    Topics: Burns; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; V

2020
A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2017, Volume: 43 Suppl 1

    Topics: Adolescent; Adult; Animals; Burns; Calcium Channel Blockers; Child; Child, Preschool; Cicatrix; Cica

2017
The effect of combined steroid and calcium channel blocker injection on human hypertrophic scars in animal model: a new strategy for the treatment of hypertrophic scars.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2010, Volume: 36, Issue:12

    Topics: Animals; Burns; Calcium Channel Blockers; Cell Proliferation; Cicatrix, Hypertrophic; Decorin; Disea

2010
Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase.
    European journal of pharmacology, 2008, Jun-10, Volume: 587, Issue:1-3

    Topics: Animals; Behavior, Animal; Burns; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Diltiazem; En

2008
Effects of verapamil on thermal trauma depressed cardiac output in the anaesthetized dog.
    Burns, including thermal injury, 1984, Volume: 10, Issue:5

    Topics: Animals; Blood Pressure; Burns; Cardiac Output; Dogs; Vascular Resistance; Verapamil

1984
The response of burn scars to intralesional verapamil. Report of five cases.
    Archives of surgery (Chicago, Ill. : 1960), 1994, Volume: 129, Issue:1

    Topics: Adolescent; Adult; Burns; Cicatrix, Hypertrophic; Female; Humans; Injections, Intralesional; Male; M

1994
Analysis of regional hemodynamic regulation in response to scald injury.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: Adamantane; Animals; Arginine; Atropine; Blood Pressure; Burns; Diphenhydramine; Dogs; Femoral Arter

1994
[The effect of burn sera on the calcium homeostasis in isolated rat myocardial cells].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2000, Volume: 16, Issue:3

    Topics: Animals; Burns; Calcium; Female; Homeostasis; Male; Myocardium; Procaine; Rats; Rats, Sprague-Dawley

2000
Effects of thermal trauma on cardiac force of contraction.
    Burns, including thermal injury, 1986, Volume: 12, Issue:3

    Topics: Animals; Blood Pressure; Burns; Cardiac Output; Cardiac Output, Low; Dogs; Myocardial Contraction; T

1986