Page last updated: 2024-10-24

verapamil and Brugada Syndrome

verapamil has been researched along with Brugada Syndrome in 5 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Brugada Syndrome: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.

Research Excerpts

ExcerptRelevanceReference
"Simvastatin (SV) leads to reduction of ventricular rhythm during atrial fibrillation on rabbit atrioventricular (AV) nodes."7.81Acute effects of simvastatin to terminate fast reentrant tachycardia through increasing wavelength of atrioventricular nodal reentrant tachycardia circuit. ( Alizadeh, AM; Aminolsharieh Najafi, S; Khori, V; Moheimani, HR; Nayebpour, M; Shakiba, D; Zahedi, M, 2015)
"Brugada syndrome is a disease characterized by a specific electrocardiographic pattern and an increased risk of sudden cardiac death."5.46A Report of Brugada Syndrome Presenting with Cardiac Arrest Triggered by Verapamil Intoxication. ( Atar, İ; Erdoğan, İ; Varan, B; Yakut, K, 2017)
" The Ito agonist NS5806, sodium channel blocker ajmaline, calcium channel blocker verapamil or hypothermia (32°C) were used to pharmacologically mimic the genetic defects and conditions associated with JWS, thus eliciting prominent J waves and provoking VT/VF."3.96Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes. ( Ackerman, MJ; Antzelevitch, C; Barajas-Martinez, H; Borbáth, V; Burashnikov, A; Clatot, J; Di Diego, JM; Hu, D; Li, GR; Patocskai, B; Robinson, VM, 2020)
"Simvastatin (SV) leads to reduction of ventricular rhythm during atrial fibrillation on rabbit atrioventricular (AV) nodes."3.81Acute effects of simvastatin to terminate fast reentrant tachycardia through increasing wavelength of atrioventricular nodal reentrant tachycardia circuit. ( Alizadeh, AM; Aminolsharieh Najafi, S; Khori, V; Moheimani, HR; Nayebpour, M; Shakiba, D; Zahedi, M, 2015)
"Brugada syndrome is a disease characterized by a specific electrocardiographic pattern and an increased risk of sudden cardiac death."1.46A Report of Brugada Syndrome Presenting with Cardiac Arrest Triggered by Verapamil Intoxication. ( Atar, İ; Erdoğan, İ; Varan, B; Yakut, K, 2017)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Di Diego, JM1
Patocskai, B2
Barajas-Martinez, H2
Borbáth, V1
Ackerman, MJ1
Burashnikov, A1
Clatot, J1
Li, GR1
Robinson, VM1
Hu, D2
Antzelevitch, C2
Yakut, K1
Erdoğan, İ1
Varan, B1
Atar, İ1
Koncz, I1
Gurabi, Z1
Panama, BK1
Szél, T1
Khori, V1
Alizadeh, AM1
Moheimani, HR1
Zahedi, M1
Aminolsharieh Najafi, S1
Shakiba, D1
Nayebpour, M1
Morita, H1
Zipes, DP1
Morita, ST1
Wu, J1

Other Studies

5 other studies available for verapamil and Brugada Syndrome

ArticleYear
Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Ajmaline; Animals; Brugada Syndrome; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Ele

2020
A Report of Brugada Syndrome Presenting with Cardiac Arrest Triggered by Verapamil Intoxication.
    Balkan medical journal, 2017, 12-01, Volume: 34, Issue:6

    Topics: Adolescent; Ajmaline; Anti-Arrhythmia Agents; Brugada Syndrome; Diagnosis, Differential; Electrocard

2017
Mechanisms underlying the development of the electrocardiographic and arrhythmic manifestations of early repolarization syndrome.
    Journal of molecular and cellular cardiology, 2014, Volume: 68

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac

2014
Acute effects of simvastatin to terminate fast reentrant tachycardia through increasing wavelength of atrioventricular nodal reentrant tachycardia circuit.
    Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node; Brugada Syndrome; Cardiac

2015
Genotype-phenotype correlation in tissue models of Brugada syndrome simulating patients with sodium and calcium channelopathies.
    Heart rhythm, 2010, Volume: 7, Issue:6

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Body Surface Potential

2010