verapamil has been researched along with Bronchial Spasm in 22 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-four patients who were known to develop bronchoconstriction in response to isocapnic hyperventilation (IH) took part in a double-blind, placebo-controlled trial to assess the effects of verapamil (5 mg) and sodium cromoglycate (SCG) 20 mg in the prevention of IH-induced bronchoconstriction." | 9.05 | Effects of verapamil and sodium cromoglycate on bronchoconstriction induced by isocapnic hyperventilation. ( Biggs, BA; Fergusson, RJ; Grant, IW; Rafferty, P; Tweeddale, PM, 1985) |
| "The extracellular calcium antagonists, nifedipine and verapamil, the mixed extra/intracellular calcium antagonist diazoxide and the intracellular calcium antagonist TMB-8 were studied for their effects on histamine-induced bronchospasm in guinea pigs and on antigen-induced bronchospasms in guinea pigs and rats when administered directly to the tracheobronchial tree." | 7.67 | Effect of extra- and intracellular calcium blockers on histamine and antigen-induced bronchospasms in guinea pigs and rats. ( Chapman, RW; Danko, G; Siegel, MI, 1984) |
| "The protective effect was studied of the drugs blocking the calcium channel on histamine-induced bronchospasm." | 5.06 | [Evaluation of the protective effects of nifedipine and verapamil in patients with bronchial hyperreactivity]. ( Frank-Piskorska, A; Malinowski, R; Wasek, Z, 1989) |
| "Twenty-four patients who were known to develop bronchoconstriction in response to isocapnic hyperventilation (IH) took part in a double-blind, placebo-controlled trial to assess the effects of verapamil (5 mg) and sodium cromoglycate (SCG) 20 mg in the prevention of IH-induced bronchoconstriction." | 5.05 | Effects of verapamil and sodium cromoglycate on bronchoconstriction induced by isocapnic hyperventilation. ( Biggs, BA; Fergusson, RJ; Grant, IW; Rafferty, P; Tweeddale, PM, 1985) |
| "The extracellular calcium antagonists, nifedipine and verapamil, the mixed extra/intracellular calcium antagonist diazoxide and the intracellular calcium antagonist TMB-8 were studied for their effects on histamine-induced bronchospasm in guinea pigs and on antigen-induced bronchospasms in guinea pigs and rats when administered directly to the tracheobronchial tree." | 3.67 | Effect of extra- and intracellular calcium blockers on histamine and antigen-induced bronchospasms in guinea pigs and rats. ( Chapman, RW; Danko, G; Siegel, MI, 1984) |
| "Calcium antagonist, verapamil given by inhalation did not alter histamine bronchial hyper-reactivity in ten patients with extrinsic bronchial asthma and similarly did not modify methacholine-induced bronchoconstriction in further five patients." | 3.66 | The effect of verapamil on histamine and methacholine-induced bronchoconstriction. ( Patel, KR, 1981) |
| " These results suggest that verapamil, at the dosage used, did not prevent allergic bronchoconstriction by a direct action on smooth muscle and therefore was effective by inhibiting the release of mast cell mediators." | 1.27 | Modification of allergic bronchoconstriction by a calcium antagonist: mode of action. ( Abraham, WM; Ahmed, T; Marchette, B; Russi, EW; Yerger, L, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (95.45) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Townley, RG | 1 |
| Malo, PE | 1 |
| Wasserman, MA | 1 |
| Griffin, RL | 1 |
| Ritchie, DM | 1 |
| Sierchio, JN | 1 |
| Bishop, CM | 1 |
| Hedli, CC | 1 |
| Levinson, SL | 1 |
| Capetola, RJ | 1 |
| Solway, J | 2 |
| König, P | 1 |
| Chapman, RW | 1 |
| Danko, G | 1 |
| Siegel, MI | 1 |
| Popa, VT | 1 |
| Somani, P | 1 |
| Simon, V | 1 |
| McIntyre, E | 1 |
| Fitzgibbon, B | 1 |
| Otto, H | 1 |
| Minson, R | 1 |
| Alpers, J | 1 |
| Ruffin, R | 1 |
| Russi, EW | 2 |
| Marchette, B | 1 |
| Yerger, L | 1 |
| Abraham, WM | 2 |
| Ahmed, T | 3 |
| Zsotér, TT | 1 |
| Patel, KR | 1 |
| Taylor, SG | 1 |
| Arch, JR | 1 |
| Bond, J | 1 |
| Buckle, DR | 1 |
| Shaw, DJ | 1 |
| Taylor, JF | 1 |
| Ward, JS | 1 |
| Berman, BA | 1 |
| Ross, RN | 1 |
| Malinowski, R | 2 |
| Wasek, Z | 2 |
| Frank-Piskorska, A | 2 |
| Carpenter, N | 1 |
| D'Brot, J | 1 |
| Kim, CS | 1 |
| Kardaszewicz, B | 1 |
| Danek, K | 1 |
| Rafferty, P | 1 |
| Fergusson, RJ | 1 |
| Tweeddale, PM | 1 |
| Biggs, BA | 1 |
| Grant, IW | 1 |
| Danta, I | 1 |
| Krasnowska, M | 1 |
| Liebhart, E | 1 |
| Małolepszy, J | 1 |
| Fanta, CH | 1 |
| Filias, N | 1 |
3 reviews available for verapamil and Bronchial Spasm
| Article | Year |
|---|---|
Calcium antagonists.
Topics: Action Potentials; Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Bronchial Spasm; | 1980 |
Treating coexisting cardiovascular and pulmonary disease with calcium antagonists.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Asthma, Exercise-Induced; Bronchial Spasm; Calcium; Ca | 1986 |
[Use of calcium antagonists in the treatment of bronchial asthma].
Topics: Animals; Asthma; Bronchi; Bronchial Spasm; Bronchodilator Agents; Clinical Trials as Topic; Drug Eva | 1986 |
5 trials available for verapamil and Bronchial Spasm
| Article | Year |
|---|---|
Inhaled verapamil in histamine-induced bronchoconstriction.
Topics: Adult; Bronchial Diseases; Bronchial Provocation Tests; Bronchial Spasm; Constriction, Pathologic; D | 1983 |
[Evaluation of the protective effects of nifedipine and verapamil in patients with bronchial hyperreactivity].
Topics: Administration, Inhalation; Adult; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agen | 1989 |
[Use of calcium antagonists in the treatment of bronchial asthma].
Topics: Animals; Asthma; Bronchi; Bronchial Spasm; Bronchodilator Agents; Clinical Trials as Topic; Drug Eva | 1986 |
Effects of verapamil and sodium cromoglycate on bronchoconstriction induced by isocapnic hyperventilation.
Topics: Asthma, Exercise-Induced; Bronchial Spasm; Cromolyn Sodium; Female; Humans; Hyperventilation; Male; | 1985 |
Differential inhibition of bronchoconstriction by the calcium channel blockers, verapamil and nifedipine.
Topics: Adult; Bronchial Provocation Tests; Bronchial Spasm; Calcium Channel Blockers; Cold Temperature; Fem | 1985 |
15 other studies available for verapamil and Bronchial Spasm
| Article | Year |
|---|---|
Role of calcium channel blocking agents in the treatment of allergic asthma.
Topics: Animals; Asthma; Basophils; Bronchial Provocation Tests; Bronchial Spasm; Calcium; Calcium Channel B | 1984 |
The effects of nifedipine and verapamil on antigen-induced bronchoconstriction in dogs.
Topics: Animals; Antigens; Ascaris; Bronchial Spasm; Dogs; Female; Histamine Release; Male; Nifedipine; Vera | 1983 |
Evaluation of calcium entry blockers in several models of immediate hypersensitivity.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acids; Bronchial Spasm; Calcium Channel Blockers; C | 1984 |
Calcium channel blocking agents in bronchial hyperreactivity.
Topics: Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; C | 1984 |
The use of cromolyn in the management of hyperreactive airways and exercise.
Topics: Adult; Aerosols; Angioedema; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Child; Cold Temperat | 1984 |
Effect of extra- and intracellular calcium blockers on histamine and antigen-induced bronchospasms in guinea pigs and rats.
Topics: Albuterol; Animals; Bronchial Spasm; Calcium Channel Blockers; Diazoxide; Gallic Acid; Guinea Pigs; | 1984 |
The effect of inhaled verapamil on resting bronchial tone and airway contractions induced by histamine and acetylcholine in normal and asthmatic subjects.
Topics: Acetylcholine; Adult; Airway Resistance; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Dose | 1984 |
Modification of allergic bronchoconstriction by a calcium antagonist: mode of action.
Topics: Airway Resistance; Animals; Antigens; Ascaris; Bronchi; Bronchial Spasm; Carbachol; Histamine Antago | 1983 |
The effect of verapamil on histamine and methacholine-induced bronchoconstriction.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Expiratory V | 1981 |
The inhibitory effects of cromakalim and its active enantiomer BRL 38227 against various agonists in guinea pig and human airways: comparison with pinacidil and verapamil.
Topics: Animals; Benzopyrans; Bronchi; Bronchial Spasm; Bronchodilator Agents; Carbachol; Cromakalim; Drug I | 1992 |
[Study of the effects of calcium antagonists on respiration mechanics in patients with occlusive ventilation impairment].
Topics: Adult; Bronchial Spasm; Calcium Channel Blockers; Diltiazem; Female; Humans; Male; Middle Aged; Nife | 1989 |
Effect of gallopamil, a calcium channel blocker, on carbachol- and histamine-induced bronchoconstriction in sheep.
Topics: Aerosols; Airway Resistance; Animals; Bronchial Spasm; Carbachol; Female; Gallopamil; Histamine; Inf | 1988 |
Comparative modification of antigen-induced bronchoconstriction by the calcium antagonists, nifedipine and verapamil.
Topics: Adult; Antigens; Bronchial Provocation Tests; Bronchial Spasm; Calcium Channel Blockers; Evaluation | 1985 |
[Effect of verapamil on post-histamine bronchial spasm].
Topics: Adult; Bronchial Provocation Tests; Bronchial Spasm; Female; Histamine; Histamine Antagonists; Human | 1985 |
[Treatment of cardiac arrhythmias with Verapamil (author's transl)].
Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Bronchial Spasm; Female; He | 1974 |