verapamil has been researched along with Brain Neoplasms in 15 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " As a novel type of nano-radiosensitizer, silver nanoparticles (AgNPs) have shown promising radiosensitizing properties in the radiotherapy of glioma, but their ability to efficiently enter and accumulate in tumor cells needs to be improved." | 8.02 | Increasing the accumulation of aptamer AS1411 and verapamil conjugated silver nanoparticles in tumor cells to enhance the radiosensitivity of glioma. ( Cao, Y; Chen, W; Li, D; Liu, P; Ma, J; Yang, H; Zhao, J, 2021) |
| " As a novel type of nano-radiosensitizer, silver nanoparticles (AgNPs) have shown promising radiosensitizing properties in the radiotherapy of glioma, but their ability to efficiently enter and accumulate in tumor cells needs to be improved." | 4.02 | Increasing the accumulation of aptamer AS1411 and verapamil conjugated silver nanoparticles in tumor cells to enhance the radiosensitivity of glioma. ( Cao, Y; Chen, W; Li, D; Liu, P; Ma, J; Yang, H; Zhao, J, 2021) |
| "Membrane-modifying agents such as reserpine, calcium antagonists (nicardipine, verapamil) and calmodulin inhibitor (trifluoperazine) were found to enhance the cytotoxicity of ACNU in vitro and in vivo in ACNU-resistant C 6 (C 6/ACNU) glioma." | 3.67 | [Possibility of overcoming of ACNU resistance in an ACNU-resistant subline of C6 rat glioma]. ( Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, J | 1 |
| Li, D | 1 |
| Ma, J | 1 |
| Yang, H | 1 |
| Chen, W | 1 |
| Cao, Y | 1 |
| Liu, P | 1 |
| Hanif, F | 1 |
| Perveen, K | 1 |
| Malhi, SM | 1 |
| Jawed, H | 1 |
| Simjee, SU | 1 |
| Zanotti-Fregonara, P | 1 |
| Veronese, M | 1 |
| Pascual, B | 1 |
| Rostomily, RC | 1 |
| Turkheimer, F | 1 |
| Masdeu, JC | 1 |
| Mrozikiewicz, PM | 1 |
| Bogacz, A | 1 |
| Bartkowiak-Wieczorek, J | 1 |
| Kujawski, R | 1 |
| Mikolajczak, PL | 1 |
| Ozarowski, M | 1 |
| Czerny, B | 1 |
| Mrozikiewicz-Rakowska, B | 1 |
| Grzeskowiak, E | 1 |
| Bedford, RF | 1 |
| Dacey, R | 1 |
| Winn, HR | 1 |
| Lynch, C | 1 |
| Matsukado, K | 1 |
| Ikezaki, K | 1 |
| Nomura, T | 1 |
| Fukui, M | 1 |
| Ducharme, J | 1 |
| Abdullah, S | 1 |
| Wainer, IW | 1 |
| Straub, H | 1 |
| Köhling, R | 1 |
| Lüke, A | 1 |
| Fauteck, JD | 1 |
| Speckmann, EJ | 1 |
| Moskopp, D | 1 |
| Wassmann, H | 1 |
| Tuxhorn, I | 1 |
| Wolf, P | 1 |
| Pannek, H | 1 |
| Oppel, F | 1 |
| Saqr, HE | 1 |
| Guan, Z | 1 |
| Yates, AJ | 1 |
| Stokes, BT | 1 |
| Rieger, L | 1 |
| Rieger, J | 1 |
| Winter, S | 1 |
| Streffer, J | 1 |
| Esser, P | 1 |
| Dichgans, J | 1 |
| Meyermann, R | 1 |
| Weller, M | 1 |
| Andersson, U | 1 |
| Grankvist, K | 1 |
| Bergenheim, AT | 1 |
| Behnam-Motlagh, P | 1 |
| Hedman, H | 1 |
| Henriksson, R | 1 |
| Bowles, AP | 1 |
| Pantazis, CG | 1 |
| Wansley, W | 1 |
| Yoshida, T | 2 |
| Shimizu, K | 2 |
| Ushio, Y | 2 |
| Hayakawa, T | 1 |
| Kato, A | 1 |
| Mogami, H | 2 |
| Sakamoto, Y | 2 |
| Kaba, K | 1 |
| Tani, E | 1 |
| Morimura, T | 1 |
| Matsumoto, T | 1 |
1 trial available for verapamil and Brain Neoplasms
| Article | Year |
|---|---|
Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity.
Topics: Adult; Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Brain Neoplasms; Chromatogr | 1996 |
14 other studies available for verapamil and Brain Neoplasms
| Article | Year |
|---|---|
Increasing the accumulation of aptamer AS1411 and verapamil conjugated silver nanoparticles in tumor cells to enhance the radiosensitivity of glioma.
Topics: Aptamers, Nucleotide; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Metal Nanoparticles; Oligod | 2021 |
Verapamil potentiates anti-glioblastoma efficacy of temozolomide by modulating apoptotic signaling.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug S | 2018 |
The validity of
Topics: Animals; Biomarkers; Biopsy; Blood-Brain Barrier; Brain; Brain Neoplasms; Carbazoles; Fluorine Radio | 2019 |
Screening for impact of popular herbs improving mental abilities on the transcriptional level of brain transporters.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Neoplasms; Ginkgo biloba; Hypericum | 2014 |
Adverse impact of a calcium entry-blocker (verapamil) on intracranial pressure in patients with brain tumors.
Topics: Brain Neoplasms; Humans; Intracranial Pressure; Verapamil | 1983 |
Effect of calcium antagonists on regional cerebral blood flow in transplanted rat brain tumors.
Topics: Analysis of Variance; Animals; Brain; Brain Neoplasms; Calcium Channel Blockers; Cerebrovascular Cir | 1996 |
The effects of verapamil and flunarizine on epileptiform activity induced by bicuculline and low Mg2+ in neocortical tissue of epileptic and primary non-epileptic patients.
Topics: Astrocytoma; Bicuculline; Brain Neoplasms; Cerebral Cortex; Ependymoma; Epilepsy, Frontal Lobe; Epil | 1996 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium | 1999 |
Evidence for a constitutive, verapamil-sensitive, non-P-glycoprotein multidrug resistance phenotype in malignant glioma that is unaltered by radiochemotherapy in vivo.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, | 2000 |
Rapid induction of long-lasting drug efflux activity in brain vascular endothelial cells but not malignant glioma following irradiation.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2002 |
Use of verapamil to enhance the antiproliferative activity of BCNU in human glioma cells: an in vitro and in vivo study.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Drug Screening Assays, Antitumor; Fluorescent D | 1990 |
[Mechanism and overcoming of resistance in ACNU-resistant sublines of rat brain tumors].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Membrane Permeability; Drug Resistance; Glioma | 1986 |
[Possibility of overcoming of ACNU resistance in an ACNU-resistant subline of C6 rat glioma].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Cells, Cultured; Drug Resistance; Drug T | 1986 |
Potentiation of vincristine effect in human and murine gliomas by calcium channel blockers or calmodulin inhibitors.
Topics: Animals; Brain Neoplasms; Calcium Channel Blockers; Calmodulin; Drug Synergism; Glioma; Humans; In V | 1985 |