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verapamil and Bone Loss, Osteoclastic

verapamil has been researched along with Bone Loss, Osteoclastic in 7 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
" The dose-response curve for forskolin-induced bone mineral release (24 hrs), however, demonstrated a biphasic character, showing stimulation at 0."1.27Different roles for calcium and cyclic AMP in the action of PTH: studies in bone explants and isolated bone cells. ( Boonekamp, PM; Herrmann-Erlee, MP; Löwik, CW; van der Meer, JM; van Leeuwen, JP, 1988)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lerner, U2
Gustafson, GT1
Redlich, K1
Pietschmann, P1
Stulc, T1
Peterlik, M1
Krieger, NS1
Zheng, MH1
Wood, DJ1
Papadimitriou, JM1
Nicholson, GC1
Chagnac, A1
Gazit, D1
Zahavi, I1
Sela, J1
Levi, J1
Herrmann-Erlee, MP1
van der Meer, JM1
Löwik, CW1
van Leeuwen, JP1
Boonekamp, PM1
Fredholm, BB1
Hänström, L1

Other Studies

7 other studies available for verapamil and Bone Loss, Osteoclastic

ArticleYear
Inhibition of 1 alpha-hydroxy-vitamin D3 stimulated bone resorption in tissue culture by the calcium antagonist verapamil.
    European journal of clinical investigation, 1982, Volume: 12, Issue:2

    Topics: Animals; Bone Resorption; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Glucuronidase; H

1982
Comparative study on the effect of calcium channel blockers on basal and parathyroid hormone-induced bone resorption in vitro.
    Pharmacology & toxicology, 1997, Volume: 80, Issue:6

    Topics: Amlodipine; Animals; Bone Resorption; Calcium Channel Blockers; Gallopamil; Mice; Nifedipine; Organ

1997
Demonstration of sodium/calcium exchange in rodent osteoblasts.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:9

    Topics: Animals; Biological Transport, Active; Bone Resorption; Calcium; Carrier Proteins; Cells, Cultured;

1992
Evidence that protein kinase-A, calcium-calmodulin kinase and cytoskeletal proteins are involved in osteoclast retraction induced by calcitonin.
    Experimental and molecular pathology, 1992, Volume: 57, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Resorption; Calcitonin; Cells, Cultured

1992
Effect of verapamil on bone resorption and formation in uremic rats.
    Mineral and electrolyte metabolism, 1989, Volume: 15, Issue:5

    Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Creatinine; Hyperparathyroidism; Kidney Failure,

1989
Different roles for calcium and cyclic AMP in the action of PTH: studies in bone explants and isolated bone cells.
    Bone, 1988, Volume: 9, Issue:2

    Topics: Animals; Bone and Bones; Bone Resorption; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AM

1988
Diphenylhydantoin inhibits parathyroid hormone and prostaglandin E2-stimulated bone resorption in mouse calvaria without affecting cyclic AMP formation.
    Journal of oral pathology, 1985, Volume: 14, Issue:8

    Topics: Animals; Bone Resorption; Calcium; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Glyco

1985