verapamil has been researched along with Bilateral Headache in 29 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the treatment of angina pectoris a double-blind evaluation of verapamil (Cordilox) at two dose levels-namely, 80 mg thrice daily and 120 mg thrice daily-propranolol (Inderal) 100 mg thrice daily, and isosorbide dinitrate (Vascardin) 20 mg thrice daily has been made against a placebo." | 9.04 | Double-blind evaluation of verapamil, propranolol, and isosorbide dinitrate against a placebo in the treatment of angina pectoris. ( Campbell, RC; Catley, PF; Livesley, B; Oram, S, 1973) |
| "Ninety patients, 50 males and 40 females, and their ages ranged between 42 and 70 years, with severe hypertension were treated by either sublingual verapamil tablets 40 mg (30 patients) or 80 mg (30 patients) or sublingual nifedipine capsules 10 mg (30 patients)." | 7.70 | Efficacy of sublingual verapamil in patients with severe essential hypertension: comparison with sublingual nifedipine. ( Al-Waili, NS; Hasan, NA, 1999) |
| " A long-term, open clinical trial of verapamil therapy was conducted in ninety-three patients with coronary artery disease, selected on the basis of having stable angina pectoris and of being unsuitable for treatment with beta-adrenoceptor blocking drugs." | 7.66 | Verapamil in the long-term treatment of angina pectoris. ( Raftos, J, 1982) |
| " This verapamil formulation can be clinically titrated within a 180 to 540 mg dosing range, permitting effective once-daily administration for the treatment of chronic stable angina." | 6.68 | Placebo-controlled evaluation of three doses of a controlled-onset, extended-release formulation of verapamil in the treatment of stable angina pectoris. ( Anders, RJ; Awan, NA; Bultas, J; Cutler, NR; Jhee, SS; Lahiri, A; Sramek, JJ; Woroszylska, M, 1995) |
| "In the treatment of angina pectoris a double-blind evaluation of verapamil (Cordilox) at two dose levels-namely, 80 mg thrice daily and 120 mg thrice daily-propranolol (Inderal) 100 mg thrice daily, and isosorbide dinitrate (Vascardin) 20 mg thrice daily has been made against a placebo." | 5.04 | Double-blind evaluation of verapamil, propranolol, and isosorbide dinitrate against a placebo in the treatment of angina pectoris. ( Campbell, RC; Catley, PF; Livesley, B; Oram, S, 1973) |
| " Concomitant verapamil therapy for hypertension did not prevent the vasospastic effects of dihydroergotamine." | 3.77 | Dihydroergotamine-induced vasospastic angina in a patient taking a calcium channel blocker. ( Johnson, BD; Schenkat, DH; Schulz, LT, 2011) |
| "Hemicrania continua (HC) is a rare headache syndrome, typically responsive to indomethacin, although patients resistant to this drug have been described." | 3.73 | Hemicrania continua responsive to verapamil. ( Jacob, S; Rajabally, YA, 2005) |
| "Ninety patients, 50 males and 40 females, and their ages ranged between 42 and 70 years, with severe hypertension were treated by either sublingual verapamil tablets 40 mg (30 patients) or 80 mg (30 patients) or sublingual nifedipine capsules 10 mg (30 patients)." | 3.70 | Efficacy of sublingual verapamil in patients with severe essential hypertension: comparison with sublingual nifedipine. ( Al-Waili, NS; Hasan, NA, 1999) |
| " A long-term, open clinical trial of verapamil therapy was conducted in ninety-three patients with coronary artery disease, selected on the basis of having stable angina pectoris and of being unsuitable for treatment with beta-adrenoceptor blocking drugs." | 3.66 | Verapamil in the long-term treatment of angina pectoris. ( Raftos, J, 1982) |
| " This verapamil formulation can be clinically titrated within a 180 to 540 mg dosing range, permitting effective once-daily administration for the treatment of chronic stable angina." | 2.68 | Placebo-controlled evaluation of three doses of a controlled-onset, extended-release formulation of verapamil in the treatment of stable angina pectoris. ( Anders, RJ; Awan, NA; Bultas, J; Cutler, NR; Jhee, SS; Lahiri, A; Sramek, JJ; Woroszylska, M, 1995) |
| "Trigeminal autonomic cephalalgias (TACs) are a group of primary headache syndromes characterised by two main clinical characteristics: pain and oculofacial autonomic phenomena." | 2.42 | Strategies for the treatment of autonomic trigeminal cephalalgias. ( Broggi, G; Bussone, G; Curone, M; D'Amico, D; D'Andrea, G; Franzini, A; Grazzi, L; Leone, M; Mea, E; Tullo, V, 2004) |
| "Headaches are a common entity in the ambulatory population." | 2.40 | Diagnosis, prophylaxis, and treatment of headaches in the athlete. ( Kaplan, B; Swain, RA, 1997) |
| "Episodic cluster headache is more responsive to acute therapy than chronic." | 1.62 | Real-life treatment of cluster headache in a tertiary headache center - results from the Danish Cluster Headache Survey. ( Barloese, M; Jensen, RH; Lund, N; Petersen, AS, 2021) |
| "Headache is a significant problem with the suboccipital approach for acoustic tumor removal." | 1.30 | Medical treatment of headache after suboccipital acoustic tumor removal. ( Brandes, JL; Glasscock, ME; Hanson, MB; Jackson, CG, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (24.14) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 11 (37.93) | 29.6817 |
| 2010's | 4 (13.79) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Perez, DJ | 1 |
| Petersen, AS | 1 |
| Lund, N | 1 |
| Jensen, RH | 1 |
| Barloese, M | 1 |
| Khvan, M | 1 |
| Vento, S | 1 |
| Kaya, I | 1 |
| Eraslan, S | 1 |
| Tarhan, C | 1 |
| Bilgen, C | 1 |
| Kirazli, T | 1 |
| Gokcay, F | 1 |
| Karapolat, H | 1 |
| Celebisoy, N | 1 |
| Chia, NH | 1 |
| Kleinig, TJ | 1 |
| Fletcher, JJ | 1 |
| Kramer, AH | 1 |
| Bleck, TP | 1 |
| Solenski, NJ | 1 |
| Schenkat, DH | 1 |
| Schulz, LT | 1 |
| Johnson, BD | 1 |
| Stoeckelhuber, BM | 1 |
| Suttmann, I | 1 |
| Stoeckelhuber, M | 1 |
| Kueffer, G | 1 |
| D'Andrea, G | 2 |
| Terrazzino, S | 1 |
| Leon, A | 1 |
| Fortin, D | 1 |
| Perini, F | 1 |
| Granella, F | 1 |
| Bussone, G | 2 |
| Leone, M | 1 |
| Franzini, A | 1 |
| D'Amico, D | 1 |
| Grazzi, L | 1 |
| Mea, E | 1 |
| Curone, M | 1 |
| Tullo, V | 1 |
| Broggi, G | 1 |
| Henry, A | 1 |
| Charpiat, B | 1 |
| Vial, T | 1 |
| Franchini, S | 1 |
| Cuilleret, FJ | 1 |
| Milon, H | 1 |
| Narbone, MC | 1 |
| Gangemi, S | 1 |
| Abbate, M | 1 |
| Rajabally, YA | 1 |
| Jacob, S | 1 |
| Rozen, TD | 1 |
| Uchino, M | 1 |
| Haga, D | 1 |
| Nomoto, J | 1 |
| Mito, T | 1 |
| Kuramitsu, T | 1 |
| Ducros, A | 1 |
| Rahn, KH | 1 |
| Raftos, J | 1 |
| Resnekov, L | 1 |
| Cutler, NR | 1 |
| Anders, RJ | 1 |
| Jhee, SS | 1 |
| Sramek, JJ | 1 |
| Awan, NA | 1 |
| Bultas, J | 1 |
| Lahiri, A | 1 |
| Woroszylska, M | 1 |
| Swain, RA | 1 |
| Kaplan, B | 1 |
| Hanson, MB | 1 |
| Glasscock, ME | 1 |
| Brandes, JL | 1 |
| Jackson, CG | 1 |
| Al-Waili, NS | 1 |
| Hasan, NA | 1 |
| van Poeck, KJ | 1 |
| Evans, RW | 1 |
| Packard, RC | 1 |
| Berman, BA | 1 |
| Ross, RN | 1 |
| De Gregorio, G | 1 |
| Restivo, S | 1 |
| De Gregorio, C | 1 |
| Solomon, GD | 1 |
| Freitag, FG | 1 |
| Millstein, E | 1 |
| Mehta, N | 1 |
| Diamond, S | 1 |
| Livesley, B | 1 |
| Catley, PF | 1 |
| Campbell, RC | 1 |
| Oram, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Understanding the Role of the External Carotid Artery in the Pathophysiology of Migraine Pain[NCT03026101] | 20 participants (Anticipated) | Interventional | 2017-01-31 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for verapamil and Bilateral Headache
| Article | Year |
|---|---|
Strategies for the treatment of autonomic trigeminal cephalalgias.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Autonomic Nervous System Diseases; Calcium Channe | 2004 |
Brainstem involvement in hypertensive encephalopathy: a report of two cases and literature review.
Topics: Adult; Blood Pressure; Brain Stem; Cerebral Hemorrhage; Confusion; Headache; Humans; Hypertensive En | 2007 |
[Acute and chronic headaches].
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2006 |
Diagnosis, prophylaxis, and treatment of headaches in the athlete.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; | 1997 |
Treating coexisting cardiovascular and pulmonary disease with calcium antagonists.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Asthma, Exercise-Induced; Bronchial Spasm; Calcium; Ca | 1986 |
3 trials available for verapamil and Bilateral Headache
| Article | Year |
|---|---|
Placebo-controlled evaluation of three doses of a controlled-onset, extended-release formulation of verapamil in the treatment of stable angina pectoris.
Topics: Adult; Aged; Analysis of Variance; Angina Pectoris; Chronic Disease; Constipation; Delayed-Action Pr | 1995 |
[Cerebrovascular effects of verapamil and prevention of headache. Clinico-experimental control].
Topics: Adult; Blood Pressure; Cardiovascular Diseases; Cerebrovascular Circulation; Clinical Trials as Topi | 1987 |
Double-blind evaluation of verapamil, propranolol, and isosorbide dinitrate against a placebo in the treatment of angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Exercise Test; Female; Furan | 1973 |
21 other studies available for verapamil and Bilateral Headache
| Article | Year |
|---|---|
Empiric use of oxygen for acute atraumatic, unilateral, retro-orbital headaches.
Topics: Acute Disease; Headache; Humans; Hyperbaric Oxygenation; Male; Treatment Outcome; Verapamil; Young A | 2020 |
Real-life treatment of cluster headache in a tertiary headache center - results from the Danish Cluster Headache Survey.
Topics: Cluster Headache; Cross-Sectional Studies; Denmark; Headache; Humans; Oxygen; Sumatriptan; Surveys a | 2021 |
Successful Treatment with Verapamil and Oxygen for Hemodialysis-Related Headache in a 15 Year Old Girl.
Topics: Adolescent; Calcium Channel Blockers; Female; Headache; Humans; Oxygen; Oxygen Inhalation Therapy; R | 2016 |
Can verapamil be effective in controlling vertigo and headache attacks in vestibular migraine accompanied with Meniere's disease? A preliminary study.
Topics: Adult; Calcium Channel Blockers; Female; Headache; Humans; Male; Meniere Disease; Middle Aged; Migra | 2019 |
Verapamil-responsive coital cephalalgia as reversible cerebral vasoconstriction prodrome.
Topics: Cerebral Angiography; Female; Headache; Humans; Imaging, Three-Dimensional; Middle Aged; Vasoconstri | 2014 |
Overlapping features of eclampsia and postpartum angiopathy.
Topics: Adult; Cerebrovascular Disorders; Eclampsia; Female; Headache; Humans; Methylprednisolone; Nicardipi | 2009 |
Dihydroergotamine-induced vasospastic angina in a patient taking a calcium channel blocker.
Topics: Angina Pectoris; Calcium Channel Blockers; Coronary Vasospasm; Dihydroergotamine; Drug Interactions; | 2011 |
Comparison of the vasodilating effect of nitroglycerin, verapamil, and tolazoline in hand angiography.
Topics: Adult; Aged; Angiography; Contrast Media; Erythema; Female; Hand; Headache; Hot Temperature; Humans; | 2003 |
Elevated levels of circulating trace amines in primary headaches.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Cluster Headache; Diet; Female; Headache; H | 2004 |
Pheochromocytoma unmasked by amisulpride and tiapride.
Topics: Adult; Amisulpride; Antipsychotic Agents; Calcium Channel Blockers; Headache; Humans; Hypertension; | 2005 |
A case of SUNCT syndrome responsive to verapamil.
Topics: Brain Infarction; Cerebellum; Headache; Humans; Male; Middle Aged; Vasodilator Agents; Verapamil | 2005 |
Hemicrania continua responsive to verapamil.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Female; Headache; Humans; | 2005 |
Verapamil-responsive hemicrania continua in a patient with episodic cluster headache.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Cluster Headache; Female; | 2006 |
[Calcium antagonists in the therapy of hypertension].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Diuretics; Drug Synergism; Headache; Humans; | 1984 |
Verapamil in the long-term treatment of angina pectoris.
Topics: Angina Pectoris; Bradycardia; Calcium Channel Blockers; Constipation; Coronary Disease; Dose-Respons | 1982 |
Calcium ion blocking drugs.
Topics: Administration, Oral; Bradycardia; Calcium Channel Blockers; Diltiazem; Dizziness; Headache; Heart D | 1982 |
Medical treatment of headache after suboccipital acoustic tumor removal.
Topics: Adult; Cerebellar Neoplasms; Cerebellopontine Angle; Craniotomy; Drug Therapy, Combination; Female; | 1998 |
Efficacy of sublingual verapamil in patients with severe essential hypertension: comparison with sublingual nifedipine.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Headache; | 1999 |
[Chronic recurrent headache without neurological abnormalities. Practice guidelines of the Netherlands Society of Neurology].
Topics: Adult; Aged; Chronic Disease; Contraindications; Drug Interactions; Female; Guidelines as Topic; Hea | 1999 |
Fifteen-minute, bilateral, posttraumatic headaches.
Topics: Adult; Chronic Disease; Craniocerebral Trauma; Headache; Humans; Male; Recurrence; Time Factors; Ver | 2000 |
I.v. verapamil and negative results.
Topics: Drug Evaluation; Headache; Humans; Verapamil | 1987 |